Effect of hydralazine on vascular mechanics in a canine lobar preparation of pulmonary embolism.

abstract：INTRODUCTION:Lung cancer is the leading cause of cancer death in the USA, claiming more than 140,000 deaths annually. Delays in diagnosis and treatment can lead to missed opportunities for both curative and life prolonging therapies. This study aimed to evaluate duration of time to diagnosis and first treatment, as wel...

journal_title：Lung

authors： Albano D,Bilfinger T,Feraca M,Kuperberg S,Nemesure B

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Sildenafil was the only phosphodiesterase-5 inhibitor available for the treatment of pulmonary arterial hypertension (PAH) until the approval and availability of once-daily tadalafil. Since no direct comparative study is likely to be performed between these agents, we sought to evaluate the feasibility of tr...

journal_title：Lung

authors： Shlobin OA,Brown AW,Weir N,Ahmad S,Lemma M,Nathan SD

更新日期：2012-10-01 00:00:00

abstract：:Tracheobronchopathia osteochondroplastica (TO) is a rare disorder of the large airways characterized by the development of submucosal cartilaginous and bony nodules. The nodules involve the anterior and lateral walls and typically spare the posterior membranous wall. The clinical presentation of TO is variable and ran...

journal_title：Lung

authors： Abu-Hijleh M,Lee D,Braman SS

更新日期：2008-11-01 00:00:00

abstract：:Treatment of allergic asthma with inhaled corticosteroids results in local down-regulation of proinflammatory cytokine synthesis and in marked decrease in tissue eosinophilia. Blood concentrations of inhaled corticosteroids, although significantly lower than those measured in the lung, may still have antiinflammatory ...

journal_title：Lung

authors： Lantero S,Oddera S,Silvestri M,Gonzalez Rodriguez R,Morelli MC,Rossi GA

更新日期：1999-01-01 00:00:00

abstract：:Binding characteristics of the alpha 1-adrenergic radioloigand [3H]prazosin, and the muscarinic cholinergic radioligand, [3H]quinuclidinyl benzilate, were determined both in intact cell preparations of rat alveolar type II pneumocytes (TIIPs) and in membrane preparations of rat lung tissue. Binding in adult and neonat...

journal_title：Lung

authors： Keeney SE,Oelberg DG

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Transbronchial lung biopsy (TBBX) is a common respiratory diagnostic procedure performed to investigate several lung diseases. There are different types of forceps used to perform this procedure. The alligator and cupped (oval) forceps are most commonly used ones. To date, there are few studies that have com...

journal_title：Lung

authors： Almadani A,Ping MNY,Deenadayalu A,Saunders J,O'Brien A

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Sarcoidosis is a systemic disease in which the personal environment seems to drive a differentiated disease frequency and clinical expression. The main epidemiological studies suggest a key influence of potential environmentally linked exposures related to the type of occupation, the household, life style, s...

journal_title：Lung

authors： Ramos-Casals M,Kostov B,Brito-Zerón P,Sisó-Almirall A,Baughman RP,Autoimmune Big Data Study Group.

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:Lymphangioleiomyomatosis (LAM) is a rare, progressive, frequently lethal cystic lung disease that almost exclusively affects women. Prognostic information in LAM has been limited by small numbers and heterogeneous study methodology. Early retrospective cohorts cited 5- and 10-year mortality of 40 and 80 %, resp...

journal_title：Lung

authors： Oprescu N,McCormack FX,Byrnes S,Kinder BW

更新日期：2013-02-01 00:00:00

abstract：:The role of leukotrienes in hypoxic vasoconstriction remains controversial. Our previous study using the lipoxygenase inhibitor BW 755C in dogs failed to show a substantive role for leukotrienes in hypoxic vasoconstriction. To clarify further the role of leukotrienes, we designed 3 protocols. In the first protocol, we...

journal_title：Lung

authors： Thomas HM 3rd,Sourour MS,Lopez D,Foster SH

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:Pulmonary hypertension (PH) due to COPD has dismal prognosis. We reviewed the long-term effect of PH-target therapy in severe PH-COPD. METHOD:Patients attending our PH-clinic were reviewed for PH-COPD receiving PH-target therapy. Baseline characteristics, death/transplantation until 2014, therapy, NYHA functio...

journal_title：Lung

authors： Fossati L,Müller-Mottet S,Hasler E,Speich R,Bloch KE,Huber LC,Ulrich Somaini S

更新日期：2014-12-01 00:00:00

abstract：:Pneumocystis carinii pneumonia (PCP) is the most common presenting symptom in patients with the acquired immunodeficiency syndrome (AIDS). Clinical trials have shown that inhaled pentamidine, delivered by nebulizer, is an effective prophylaxis for PCP in high-risk patients, and can be used to treat mild to moderate ep...

journal_title：Lung

authors： Newman SP,Simonds AK

更新日期：1990-01-01 00:00:00

abstract：:The aim of our study was to evaluate clinical diagnoses in symptomatic persons exposed to aerosols from humidifiers or air conditioners. In addition, we tried to identify the causative antigens. Results of clinical investigations, including inhalation challenge tests, demonstrated a typical hypersensitivity pneumoniti...

journal_title：Lung

authors： Baur X,Behr J,Dewair M,Ehret W,Fruhmann G,Vogelmeier C,Weiss W,Zinkernagel V

更新日期：1988-01-01 00:00:00

abstract：:The transmission of forces from the respiratory muscles to the lung across the extremely thin pleural space has been poorly understood because of the difficulty of accurately measuring pleural liquid and pleural surface pressure (lung static recoil or transpulmonary pressure). Recent results using relatively noninvasi...

journal_title：Lung

authors： Lai-Fook SJ

更新日期：1987-01-01 00:00:00

abstract：INTRODUCTION:Sarcoidosis is a systemic granulomatous disease which predominantly affects the lungs, although granulomas can also involve all other organs, including the heart. Cardiac sarcoidosis (CS) may occur at any stage of the disease and may be the cause of sudden cardiac death, even in a previously asymptomatic p...

journal_title：Lung

authors： Martusewicz-Boros MM,Boros PW,Wiatr E,Kempisty A,Piotrowska-Kownacka D,Roszkowski-Śliż K

更新日期：2016-02-01 00:00:00

abstract：:While the care of cystic fibrosis (CF) patients has been mainly the province of pediatricians, great improvements in the therapy and life span of CF patients often results in their transition to care by adult physicians. In this review of CF, we begin with an overview of the epidemiology and genetics of the disease, w...

journal_title：Lung

authors： Bye MR,Ewig JM,Quittell LM

更新日期：1994-01-01 00:00:00

abstract：:Antidromic stimulation of vagal sensory nerves is known to produce plasma extravasation in the rat trachea. This neurogenic inflammation is thought to be mediated by substance P or other tachykinins released from sensory nerve endings. We sought to determine whether calcitonin gene-related peptide (CGRP), which is als...

journal_title：Lung

authors： Brokaw JJ,White GW

更新日期：1992-01-01 00:00:00

abstract：:Eosinophils have been shown to play a role in allergen-induced airway responses. The aim in this study was to examine the effects of TAK-661, a newly developed product as a specific inhibitory agent of eosinophil chemotaxis, on antigen-induced asthmatic responses in allergic sheep model. Seven Ascaris-sensitive, "dual...

journal_title：Lung

authors： Fujimoto K,Tsunoda T,Koizumi T,Kubo K

更新日期：2002-01-01 00:00:00

abstract：:Recent research showed group B patients express higher mortality compared to group C patients when GOLD A-D grouping is used. We aimed to compare the prognostic accuracy of three GOLD classification systems, I-IV ("pre-2011"), A-D ("2011-2016") and A-D ("2017-present") in relation to mortality, exacerbation risk, qual...

journal_title：Lung

authors： Plutinsky M,Brat K,Svoboda M,Zatloukal J,Popelkova P,Koblizek V

更新日期：2019-04-01 00:00:00

abstract：:This study evaluated the extracellular matrix (collagen and elastic fibers) in pleurodesis induced by intrapleural talc (TL) or silver nitrate (SN). Study subjects were 420 rabbits divided into two groups and sacrificed from 15 min to 12 months after the injection of the sclerosing agents at intervals previously defin...

journal_title：Lung

authors： Antonangelo L,Vargas FS,Teixeira LR,Acencio MM,Vaz MA,Filho MT,Marchi E

更新日期：2006-03-01 00:00:00

abstract：:To explore further the possible etiologic role of mycobacteria in the development of sarcoidosis, we measured free, nonbound tuberculostearic acid (TSA, 10-methyloctadecanoic), a component of mycobacteria, in the sera of subjects with sarcoidosis or active untreated pulmonary tuberculosis and in healthy controls by us...

journal_title：Lung

authors： Almenoff PL,Brooks JB,Johnson A,Lesser M

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:TB nanodiagnostics have witnessed considerable development. However, most of the published reports did not proceed beyond proof-of-concept. Our objectives are to evaluate the diagnostic accuracy of a novel nanogold assay in detecting patients with active pulmonary TB based on results of BACTEC MGIT (reference t...

journal_title：Lung

authors： El-Samadony H,Azzazy HME,Tageldin MA,Ashour ME,Deraz IM,Elmaghraby T

更新日期：2019-04-01 00:00:00

abstract：:Acid glycosaminoglycans (GAG) were quantitated and partially characterized in pleural effusions in guinea pigs with experimental allergic pleurisy. Increase of GAG in the pleural effusion preceded the increase of effusion volume. Effusion was associated with the presence of cuboidal mesothelial cells on visceral pleur...

journal_title：Lung

authors： Satoh K,Arai H,Nagai H,Ito M,Sato H,Motomiya M,Konno K

更新日期：1987-01-01 00:00:00

abstract：:Patients with untreated obstructive sleep apnea hypopnea (OSAH) are predisposed to developing hypertension, and therapy with continuous positive airway pressure (CPAP) may reduce blood pressure (BP). The purpose of this study was to assess the impact of CPAP therapy on BP in patients with OSAH. We performed a comprehe...

journal_title：Lung

authors： Alajmi M,Mulgrew AT,Fox J,Davidson W,Schulzer M,Mak E,Ryan CF,Fleetham J,Choi P,Ayas NT

更新日期：2007-03-01 00:00:00

abstract：:The normal balance between coagulation and fibrinolysis in the pleural cavity is poorly understood despite the critical role of the pleura in the movement of the lungs. To determine the fibrinolytic activity and the interaction between plasminogen activators and their inhibitors in the normal pleural space, we tested ...

journal_title：Lung

authors： Li XY,Brown GM,Lamb D,Donaldson K

更新日期：1990-01-01 00:00:00

abstract：RATIONALE:The clinical characteristics and prognostic impact of radiographic patterns of patients with nontuberculous mycobacterial lung disease (NTM-LD) are rarely evaluated. DESIGN:Patients with NTM-LD from 2007 to 2009 in a single medical center in Taiwan were identified. Their radiographic patterns were reviewed a...

journal_title：Lung

authors： Shu CC,Lee CH,Hsu CL,Wang JT,Wang JY,Yu CJ,Lee LN,TAMI Group.

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:To investigate inpatient prevalence, expenditures, and comorbidities of hospitalized patients with sarcoidosis in the USA. METHODS:Patients with sarcoidosis were identified within the Nationwide Inpatient Sample (NIS) database for the years 2013 and 2014 using the respective ICD-9 diagnostic code. Data on pati...

journal_title：Lung

authors： Ungprasert P,Wijarnpreecha K,Cheungpasitporn W,Thongprayoon C,Manatsathit W,Kröner PT

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Red cell distribution width (RDW) has been shown to be associated with adverse outcomes in left-sided heart failure, pulmonary hypertension, and in patients in the ICU. However, the role of RDW is unknown in patients with obstructive sleep apnea syndrome (OSAS), especially in OSAS patients with cardiovascula...

journal_title：Lung

authors： Ozsu S,Abul Y,Gulsoy A,Bulbul Y,Yaman S,Ozlu T

更新日期：2012-06-01 00:00:00

abstract：:The effect of tetraethylammonium (TEA) and K+ on contractions to histamine and acetylcholine have been compared in the pig isolated trachea using organ bath and sucrose-gap techniques. Histamine elicited weak contractions, compared with acetylcholine; however, these contractions were markedly potentiated by pretreatme...

journal_title：Lung

authors： Mitchell HW

更新日期：1987-01-01 00:00:00

abstract：:Lung cancer screening (LCS) is currently advocated in a subset of current or former smokers with a thirty pack-year smoking history or higher. Studies report that few patients meeting the criteria for screening are undergoing LCS. We conducted a survey to assess if barriers to LCS (race, ethnicity, and socioeconomic s...

journal_title：Lung

authors： Stephens SE,Foley KL,Miller D,Bellinger CR

更新日期：2019-12-01 00:00:00

abstract：:Pulmonary histiocytosis X is characterized by an accumulation of CD-1-positive histiocytosis X cells in the lung, which also can be found in the bronchoalveolar lavage fluid (BALF). However, it has recently been demonstrated that CD-1-positive cells can also be detected in BALF of patients with other interstitial lung...

journal_title：Lung

authors： Auerswald U,Barth J,Magnussen H

更新日期：1991-01-01 00:00:00