Vitamin E co-treatment reduces Aroclor 1254-induced impairment of reproductive neuroendocrine function in Atlantic croaker.


:We have shown previously that exposure of Atlantic croaker to a PCB mixture (Aroclor 1254) results in impaired reproductive neuroendocrine function. In addition, we have identified hypothalamic tryptophan hydroxylase (TPH), the rate-limiting enzyme in serotonin (5-hydroxytryptamine) synthesis, as a target of PCB neuroendocrine toxicity. In order to further elucidate the mechanisms of PCB neurotoxicity, the present study investigated whether PCB-induced decrease in hypothalamic TPH activity resulted from degradation of the enzyme protein. Fish were exposed to Aroclor 1254 in the diet (0.1 mg/100 g body weight (BW)/day) for 30 days. The PCB exposure elicited a significant decrease in hypothalamic TPH protein content, which could be at least partially responsible for the reduced TPH activity. To test whether a similar PCB exposure could cause oxidative damage in croaker hypothalamic tissues, we examined the formation of malondialdehyde (MDA) protein adducts as a marker of lipid peroxidation (LPO). The same dose of PCB increased the MDA-protein adduct formation in the hypothalamus. In a separate experiment, the role of vitamin E, an antioxidant, to prevent or decrease the effect of PCB on hypothalamic TPH activity and gonadal growth was examined. The vitamin E co-treatments (1 and 10 mg/100 g BW/day) with PCB significantly reduced the effects of PCB on TPH activity and gonadal growth. These results suggest possible involvement of oxidative processes in PCB neurotoxicity.


Mar Environ Res


Khan IA,Thomas P





Has Abstract


2004-08-01 00:00:00














  • Vitellogenin as biomarker for estrogenicity in flounder Platichthys flesus in the field and exposed to 17α-ethinylestradiol via food and water in the laboratory.

    abstract::The ability of 17α-ethinylestradiol (EE2) to elevate vitellogenin levels were investigated in male flounder Platichthys flesus and vitellogenin concentrations in flounders from the Danish coastal environment were determined. Male flounders were exposed to 17α-ethinylestradiol (EE2) via food or water. Average vitelloge...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Madsen LL,Korsgaard B,Pedersen KL,Bjerregaard LB,Aagaard T,Bjerregaard P

    更新日期:2013-12-01 00:00:00

  • Correlative changes in metabolism and DNA damage in turbot (Scophthalmus maximus) exposed to benzo[a]pyrene.

    abstract::Juvenile turbot (Scophthalmus maximus) were injected intraperitoneally with either corn oil or 5 mg/kg benzo[a]pyrene (BaP) dissolved in corn oil and sampled I and 3 days after injection. After 1 day, no elevation of 7-ethoxyresorufin O-deethylase (EROD) activity was observed, however bile metabolites (BaP-7,8 dihydro...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Telli-Karakoç F,Ruddock PJ,Bird DJ,Hewer A,Van Schanke A,Phillips DH,Peters LD

    更新日期:2002-09-01 00:00:00

  • Urogenital papilla feminization in male Pomatoschistus minutus from two estuaries in northwestern Iberian Peninsula.

    abstract::Recently, male urogenital papilla feminization (UGPF) in the sand goby Pomatoschistus minutus was reported in several UK estuaries with high levels of estrogenic compounds. The fact that this species is also common in southern European estuaries, together with its life-cycle characteristics, prompted us to investigate...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Rodrigues P,Reis-Henriques MA,Campos J,Santos MM

    更新日期:2006-07-01 00:00:00

  • Effects of natural current pH variability on the sea urchin Paracentrotus lividus larvae development and settlement.

    abstract::One of the most important environmental factors controlling the distribution, physiology, morphology and behaviour of marine invertebrates is ocean pH. In the last decade, the effects of decreasing ocean pH as a result of climate change processes (i.e. ocean acidification) on marine organisms have been target of much ...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: García E,Clemente S,Hernández JC

    更新日期:2018-08-01 00:00:00

  • The behaviors of microplastics in the marine environment.

    abstract::Despite the pollution of microplastics being internationally recognized, the understanding of their behaviors in marine environment is still developing. Microplastics are ubiquitous in the marine environment, with the potential to cause harm to marine ecosystem. Here, we would classify the behaviors of microplastics a...

    journal_title:Marine environmental research

    pub_type: 杂志文章,评审


    authors: Wang J,Tan Z,Peng J,Qiu Q,Li M

    更新日期:2016-02-01 00:00:00

  • Measurement of DNA single-strand breaks in gill and hemolymph cells of mussels, Mytilus sp., collected on the French Atlantic Coast.

    abstract::DNA single-strand breaks were measured by the comet assay in both gill and hemolymph cells of mussels collected in 3 sampling areas of the French coast (Pointe du Castelli, Pen Bron and Saint-Nazaire Harbour). Whole mussel tissue samples were also collected for the chemical determination of PAH, PCB and heavy metal co...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Akcha F,Tanguy A,Leday G,Pelluhet L,Budzinski H,Chiffoleau JF

    更新日期:2004-08-01 00:00:00

  • Physiological effects of hypercapnia in the deep-sea bivalve Acesta excavata (Fabricius, 1779) (Bivalvia; Limidae).

    abstract::The option of storing CO(2) in subsea rock formations to mitigate future increases in atmospheric CO(2) may induce problems for animals in the deep sea. In the present study the deep-sea bivalve Acesta excavata was subjected to environmental hypercapnia (pHSW 6.35, P(CO₂) =33,000 μatm) corresponding to conditions repo...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Hammer KM,Kristiansen E,Zachariassen KE

    更新日期:2011-09-01 00:00:00

  • Effects of man-made structures on sedimentary oxygenation: extent, seasonality and implications for offshore renewables.

    abstract::The number of man-made structures to be placed in the marine environment is set to increase massively in the near future as a consequence of the wide-scale adoption and commercialisation of offshore electricity generation. Marine renewable energy devices (MREDs) interact with their receiving environment and are de-fac...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Wilding TA

    更新日期:2014-06-01 00:00:00

  • Effects of vehicle, diet and gender on the expression of PMP70- and CYP2K1/2M1-like proteins in the mummichog.

    abstract::The mummichog (Fundulus heteroclitus) has been shown to be responsive to peroxisome proliferating agents (PPAs). Peroxisomes function as important sites for fatty acid beta-oxidation. Peroxisome proliferation by PPAs or starvation can lead to changes in the size and number of peroxisomes and the expression of omega-hy...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Haasch ML

    更新日期:2002-09-01 00:00:00

  • Applying an integrated approach to coastal marine habitat mapping in the north-western United Arab Emirates.

    abstract::Habitat mapping is essential for the management and conservation of coastal marine habitats. However, accurate and up-to-date habitat maps are rarely available for the marine realm. In this study, we mapped the coastal marine habitats of >400 km of coastline in the north-western United Arab Emirates (UAE) using a comb...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Mateos-Molina D,Antonopoulou M,Baldwin R,Bejarano I,Burt JA,García-Charton JA,Al-Ghais SM,Walgamage J,Taylor OJS

    更新日期:2020-10-01 00:00:00

  • In vivo and in vitro effects of benzothiazole on sheepshead minnow (Cyprinodon variegatus).

    abstract::Benzothiazole, a common chemical associated with tire manufacturing and industrial wastewater, is a principal component of both fresh water and estuarine tire leachate, a neurotoxicant to larval sheepshead minnows (Cyprinodon variegatus) in in vivo estuarine studies. The neurotoxic potential of benzothiazole was inves...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Evans JJ,Shoemaker CA,Klesius PH

    更新日期:2000-07-01 00:00:00

  • Bacterial community dynamic associated with autochthonous bioaugmentation for enhanced Cu phytoremediation of salt-marsh sediments.

    abstract::Autochthonous bioaugmentation for metal phytoremediation is still little explored, particularly its application to estuarine salt marshes, but results obtained so far are promising. Nevertheless, understanding the behaviour of the microbial communities in the process of bioaugmentation and their role in improving meta...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Almeida CMR,Oliveira T,Reis I,Gomes CR,Mucha AP

    更新日期:2017-12-01 00:00:00

  • Accumulation of dietary organochlorines and vitamins in Baltic seals.

    abstract::We studied the accumulation of polychlorinated biphenyls (PCBs), 1,1,1.trichloro-2,2-bis[p-chlorophenyl]ethane (DDT) and its metabolites, and vitamins A and E in the top levels of the Baltic Sea food web. The investigation focused on the transfer of contaminants and vitamins to the ringed seal (Phoca hispida baltica) ...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Routti H,Nyman M,Bäckman C,Koistinen J,Helle E

    更新日期:2005-09-01 00:00:00

  • Caprella watch: a new approach for monitoring butyltin residues in the ocean.

    abstract::A comparative study on the butyltin levels in various organisms showed that marked bioaccumulation occurs in certain lower trophic levels; i.e. from seawater to phytoplankton and into caprellid amphipods, Caprella spp. Caprella spp., which inhabit algal communities and aquaculture beds in the subtidal zone, are small ...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Takeuchi I,Takahashi S,Tanabe S,Miyazaki N

    更新日期:2001-08-01 00:00:00

  • Trophic links and nutritional condition of fish early life stages in a temperate estuary.

    abstract::The physiological and nutritional condition of fish larvae affect their survival and thus, the success of estuaries as nursery areas. Fatty acid composition has been useful to determine fish nutritional condition, as well as trophic relationships in marine organisms. The present study analyses the fatty acid (FA) comp...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Primo AL,Correia C,Marques SC,Martinho F,Leandro S,Pardal M

    更新日期:2018-02-01 00:00:00

  • Trophic ecology of the sea urchin Spatangus purpureus elucidated from gonad fatty acids composition analysis.

    abstract::Irregular sea urchins such as the spatangoid Spatangus purpureus are important bioturbators that contribute to natural biogenic disturbance and the functioning of biogeochemical cycles in soft sediments. In the coastal waters of the Balearic Islands S. purpureus occurs in soft red algal beds, and can reach high densit...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Barberá C,Fernández-Jover D,López Jiménez JA,González Silvera D,Hinz H,Moranta J

    更新日期:2011-05-01 00:00:00

  • Cloning and expression of MDR transporters from marine bivalves, and their potential use in biomonitoring.

    abstract::Multidrug resistance transporters (MDRs) are excellent candidates for molecular-level biomonitoring - they function in exporting xenobiotic compounds and their expression is inducible. However, currently available MDR sequence information from aquatic invertebrates is partial and mostly biased towards the conserved AT...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Feldstein T,Nelson N,Mokady O

    更新日期:2006-07-01 00:00:00

  • Modelling produced water dispersion and its direct toxic effects on the production and biomass of the marine copepod Calanus finmarchicus.

    abstract::Zooplankton is a key group in North Atlantic and Arctic food chains, and assessment and minimization of adverse effects from petroleum activities to this resource are important. The potential direct effects of produced water discharges on the biomass of Calanus finmarchicus were evaluated using a fully coupled, high r...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Broch OJ,Slagstad D,Smit M

    更新日期:2013-03-01 00:00:00

  • How complementary are epibenthic assemblages in artificial and nearby natural rocky reefs?

    abstract::The present study analyses the composition, structure and trophic function of epibenthic assemblages in two artificial reefs (ARs) 16 years after deployment and in nearby natural reefs (NRs), aiming at providing insights on the complementarity between both habitats. Current findings suggest that after 16 years the ARs...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Carvalho S,Moura A,Cúrdia J,Cancela da Fonseca L,Santos MN

    更新日期:2013-12-01 00:00:00

  • Spatial analysis of grain size in Santa Monica Bay.

    abstract::Maps are useful scientific tools for presenting environmental information, but the statistical techniques necessary to prepare scientifically rigorous maps have primarily focused on terrestrial habitats. This study compares three popular techniques (triangulation, kriging, and co-kriging) to map sediment grain size in...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Leecaster M

    更新日期:2003-07-01 00:00:00

  • Climate change effects on marine protected areas: Projected decline of benthic species in the North Sea.

    abstract::Climate change is a global threat for marine ecosystems, their biodiversity and consequently ecosystem services. In the marine realm, marine protected areas (MPAs) were designated to counteract regional pressures, but they might be ineffective to protect vulnerable species and habitats, if their distribution is affect...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Weinert M,Mathis M,Kröncke I,Pohlmann T,Reiss H

    更新日期:2021-01-01 00:00:00

  • Comparison of artificially weathered Macondo oil with field samples and evidence that weathering does not increase environmental acute toxicity.

    abstract::Macondo source oils and artificially weathered oil residues from 150 °C+ to 300 °C+, including artificially photo oxidized oils, were prepared and used for generating low energy water accommodated fractions (LE-WAFs) in order to assess the impact of oil weathering on WAF chemistry composition and toxicity to marine or...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Faksness LG,Altin D,Størseth TR,Nordtug T,Hansen BH

    更新日期:2020-05-01 00:00:00

  • Self-assembled monolayer-based immunoassays for okadaic acid detection in seawater as monitoring tools.

    abstract::Rapid and cost-effective methods to monitor the presence of diarrhetic shellfish poisoning (DSP) toxins in seawater samples in an easy and reliable manner are required to protect human health and avoid economic losses to shellfish industry. Immunoassays for the detection of okadaic acid (OA) and dinophysistoxin-1 and ...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Leonardo S,Toldrà A,Rambla-Alegre M,Fernández-Tejedor M,Andree KB,Ferreres L,Campbell K,Elliott CT,O'Sullivan CK,Pazos Y,Diogène J,Campàs M

    更新日期:2018-02-01 00:00:00

  • Spatial variations of dimethylsulfide and dimethylsulfoniopropionate in the surface microlayer and in the subsurface waters of the South China Sea during springtime.

    abstract::Spatial variations in dimethylsulfide (DMS) and dimethylsulfoniopropionate (DMSP) were surveyed in the surface microlayer and in the subsurface waters of the low productivity South China Sea in May 2005. Overall, average subsurface water concentrations of DMS and DMSP of dissolved (DMSPd) and particulate (DMSPp) fract...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Yang GP,Jing WW,Kang ZQ,Zhang HH,Song GS

    更新日期:2008-02-01 00:00:00

  • Indications of future performance of native and non-native adult oysters under acidification and warming.

    abstract::Globally, non-native species (NNS) have been introduced and now often entirely replace native species in captive aquaculture; in part, a result of a perceived greater resilience of NSS to climate change and disease. Here, the effects of ocean acidification and warming on metabolic rate, feeding rate, and somatic growt...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Lemasson AJ,Hall-Spencer JM,Fletcher S,Provstgaard-Morys S,Knights AM

    更新日期:2018-11-01 00:00:00

  • Fish-habitat associations on a subsea pipeline within an Australian Marine Park.

    abstract::Subsea pipelines have been installed in all major hydrocarbon basins across the globe to support the offshore Oil & Gas (O&G) industry. These artificial structures provide hard substratum that can be colonised and utilised by sessile and mobile organisms. The present study utilises industry-collected remotely operated...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: McLean DL,Vaughan BI,Malseed BE,Taylor MD

    更新日期:2019-10-10 00:00:00

  • The effects of power station entrainment passage on three species of marine planktonic crustacean, Acartia tonsa (Copepoda), Crangon crangon (Decapoda) and Homarus gammarus (Decapoda).

    abstract::Experiments have been undertaken exposing larval common shrimp (Crangon crangon) and lobster (Homarus gammarus) and adult copepods (Acartia tonsa) to the key stresses of entrainment within power-station cooling-water systems. The apparatus has enabled the testing of mechanical, thermal, chlorine and realistic pressure...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Bamber RN,Seaby RM

    更新日期:2004-05-01 00:00:00

  • Lindane toxicity: histopathological, behavioural and biochemical changes in Etroplus maculatus (Bloch, 1795).

    abstract::The effects of sub-lethal concentrations of lindane on behavioral, hematological and histological parameters in Etroplus maculatus were investigated. The LC₅₀ value of lindane for E. maculatus was estimated using the Probit method and was found to be 0.028 mg/L. The red blood cell count (RBC) and the hemoglobin (Hb), ...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Bijoy Nandan S,Nimila PJ

    更新日期:2012-05-01 00:00:00

  • Multi-marker eDNA metabarcoding survey to assess the environmental impact of three offshore gas platforms in the North Adriatic Sea (Italy).

    abstract::The environmental DNA (eDNA) metabarcoding represents a new promising tool for biomonitoring and environmental impact assessment. One of the main advantages of eDNA metabarcoding, compared to the traditional morphotaxonomy-based methods, is to provide a more holistic biodiversity information that includes inconspicuou...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Cordier T,Frontalini F,Cermakova K,Apothéloz-Perret-Gentil L,Treglia M,Scantamburlo E,Bonamin V,Pawlowski J

    更新日期:2019-04-01 00:00:00

  • Functional analysis of xenobiotic response elements (XREs) in CYP 1A of the European Flounder (Platichthys flesus).

    abstract::The induction of hepatic cytochrome P450 1A (CYP 1A) is an important step in the response to contaminants such as polycyclic aromatic hydrocarbons (PAHs), and has been used as a biomarker of exposure in fish. Several consensus response elements have been identified, including eight potential xenobiotic response elemen...

    journal_title:Marine environmental research

    pub_type: 杂志文章


    authors: Lewis N,Williams TD,Chipman K

    更新日期:2004-08-01 00:00:00