Abstract:
PURPOSE OF REVIEW:This purpose of this article is to review and provide an update of current publications on the evaluation and management of adenoid cystic carcinoma. RECENT FINDINGS:Adenoid cystic carcinoma is an uncommon salivary gland malignancy that presents insidiously and is generally advanced when diagnosed. Current effective treatment modalities include surgery and irradiation, but locoregional recurrences are frequent and may present as early as 2 years. Patients survive with recurrent and metastatic disease for several years despite not being offered any treatment. Molecular analysis of the tumors is being undertaken, with optimistic results capable of selecting high-risk patients who may benefit from adjuvant treatment such as chemotherapy SUMMARY:Little progress has been made in advancing "curative" treatment of adenoid cystic carcinoma of the head and neck. The disease is said to have a fatal outcome. The time is now opportune for a multicenter, randomized, controlled trial to identify patients who would benefit from adjuvant radiotherapy and/or chemotherapy in the control of locoregional recurrences and the prevention of distant metastases.
journal_name
Curr Opin Otolaryngol Head Neck Surgauthors
Bradley PJdoi
10.1097/00020840-200404000-00013keywords:
subject
Has Abstractpub_date
2004-04-01 00:00:00pages
127-32issue
2eissn
1068-9508issn
1531-6998pii
00020840-200404000-00013journal_volume
12pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:The identification of transcriptional activators and repressors of hair cell fates has recently been augmented by the discovery of microRNAs (miRNAs) that can function as post-transcriptional repressors in sensory hair cells. RECENT FINDINGS:miRNAs are approximately 21-nucleotide single-stranded ribo...
journal_title:Current opinion in otolaryngology & head and neck surgery
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journal_title:Current opinion in otolaryngology & head and neck surgery
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journal_title:Current opinion in otolaryngology & head and neck surgery
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更新日期:2013-04-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
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journal_title:Current opinion in otolaryngology & head and neck surgery
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journal_title:Current opinion in otolaryngology & head and neck surgery
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journal_title:Current opinion in otolaryngology & head and neck surgery
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更新日期:2016-06-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
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更新日期:2011-12-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
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doi:10.1097/MOO.0b013e32832ea999
更新日期:2009-10-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
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更新日期:2006-02-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32835ac625
更新日期:2013-02-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/00020840-200310000-00002
更新日期:2003-10-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000237
更新日期:2016-04-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000326
更新日期:2017-02-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe contemporary interpretations of 'outcomes research' in facial plastic surgery and to summarize and evaluate some of the existing validated outcome measures for use in facial plastic surgery. RECENT FINDINGS:Outcome measures can be broadly categorized into two categories - patient-reported...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3283031ac9
更新日期:2008-08-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3283465687
更新日期:2011-06-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
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更新日期:2007-06-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
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更新日期:2009-02-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
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更新日期:2009-06-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
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更新日期:2004-12-01 00:00:00
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更新日期:2020-02-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
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更新日期:2005-08-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
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更新日期:2015-04-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
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更新日期:2008-10-01 00:00:00
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journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章
doi:10.1097/MOO.0000000000000670
更新日期:2020-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Overall survival of head and neck squamous cell carcinoma patients on the whole has not dramatically improved in the last 30 years. One of the reasons is that tumour, node, metastasis classification is probably in some cases inadequate, since similar cases under a clinico-pathological point of view, m...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
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更新日期:2008-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Distraction osteogenesis is finding increasing application in the management of mandibular defects. It provides an alternative method of mandibular reconstruction in varied clinical settings, notably following trauma and ablation of malignant tumors. Many recent studies have explored modifications in ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
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更新日期:2007-08-01 00:00:00
abstract:PURPOSE OF REVIEW:The article reviews the effects of cervical osteophytosis and spine posture on swallowing, and how they can cause dysphagia. RECENT FINDINGS:Cerivical osteophytosis which is a bony overgrowth of the cervical spines, it affects the swallowing through different mechanisms, including direct mechanical c...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000488
更新日期:2018-12-01 00:00:00