Early detection of oral cancers: current status and future prospects.

Abstract:

PURPOSE OF REVIEW:This article reviews the current literature and summarizes the latest developments in screening and early detection of oral cancers and looks at the future possibilities. RECENT FINDINGS:Oral cancer is the best model for screening and prevention. The screening for oral cancer can be population based, opportunistic, or targeted. A long-term 15-year follow-up data of a randomized controlled study from a developing country setting indicated a sustained reduction in oral cancer mortality in high-risk individuals. Visual oral examination remains the mainstay in the screening. Several adjunctive techniques have been described to aid in the clinical examination of these lesions. A Cochrane review revealed that there is no evidence to recommend these adjuncts in clinically visible lesions. Salivary biomarkers seem to be promising as a tool for screening in the future. A Targeted Evidence Update for the US Preventive Services Task Force found no evidence on screening either in the general or selected high-risk population for oral cancer in the United States or on benefit of any adjunctive device affecting the performance of the screening examination. SUMMARY:Current evidence shows that community based screening has a value in reducing the oral cancer mortality in high-risk group of population. But this evidence may not be universally applicable.

authors

Iyer S,Thankappan K,Balasubramanian D

doi

10.1097/MOO.0000000000000237

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

110-4

issue

2

eissn

1068-9508

issn

1531-6998

pii

00020840-201604000-00005

journal_volume

24

pub_type

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