Incidence and management of malignant digestive endocrine tumours in a well defined French population.

abstract：OBJECTIVE:Blood vessel epicardial substance (BVES) is a tight junction-associated protein that regulates epithelial-mesenchymal states and is underexpressed in epithelial malignancy. However, the functional impact of BVES loss on tumourigenesis is unknown. Here we define the in vivo role of BVES in colitis-associated c...

journal_title：Gut

authors： Parang B,Kaz AM,Barrett CW,Short SP,Ning W,Keating CE,Mittal MK,Naik RD,Washington MK,Revetta FL,Smith JJ,Chen X,Wilson KT,Brand T,Bader DM,Tansey WP,Chen R,Brentnall TA,Grady WM,Williams CS

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:In some infants with liver disease, 3-oxo-delta 4 bile acids are the major bile acids in urine, a phenomenon attributed to reduced activity of the delta 4-3-oxosteroid 5 beta-reductase required for synthesis of chenodeoxycholic acid and cholic acid. These patients form a heterogeneous group. Many have a know...

journal_title：Gut

authors： Clayton PT,Mills KA,Johnson AW,Barabino A,Marazzi MG

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:In this consensus statement, an international panel of experts deliver their opinions on key questions regarding the contribution of the human microbiome to carcinogenesis. DESIGN:International experts in oncology and/or microbiome research were approached by personal communication to form a panel. A structu...

journal_title：Gut

authors： Scott AJ,Alexander JL,Merrifield CA,Cunningham D,Jobin C,Brown R,Alverdy J,O'Keefe SJ,Gaskins HR,Teare J,Yu J,Hughes DJ,Verstraelen H,Burton J,O'Toole PW,Rosenberg DW,Marchesi JR,Kinross JM

更新日期：2019-09-01 00:00:00

abstract：:The nervous system in the intestine controls motility, secretion, sensory perception, and immune function. Peptidergic neurones with neurotransmitters such as substance P and nerve growth factors have been the main focus of neuroimmunomodulation research in the gut. This review summarises the present knowledge concern...

journal_title：Gut

authors： Straub RH,Wiest R,Strauch UG,Härle P,Schölmerich J

更新日期：2006-11-01 00:00:00

abstract：:The cause of a biliary tract stricture may be difficult to determine radiologically. Exfoliative biliary cytology was evaluated in 62 patients (median age 65 years, range 30-94) with biliary tract strictures presenting to the Hepatobiliary Unit between January 1984 and December 1989. Bile samples were taken during end...

journal_title：Gut

authors： Davidson B,Varsamidakis N,Dooley J,Deery A,Dick R,Kurzawinski T,Hobbs K

更新日期：1992-10-01 00:00:00

abstract：:Forty five patients with refractory oesophagitis, defined as persisting erosive changes or ulceration despite a minimum of three months' treatment with cimetidine 3.2 g daily or ranitidine 0.9 g daily, were treated in an open trial with omeprazole 40 mg daily for up to eight weeks. Endoscopically defined healing was o...

journal_title：Gut

authors： Bardhan KD,Morris P,Thompson M,Dhande DS,Hinchliffe RF,Jones RB,Daly MJ,Carroll NJ

更新日期：1990-07-01 00:00:00

abstract：:This paper reviews the experience gained over the past few years in two techniques of liver support, charcoal haemoperfusion and polyacrylonitrile membrane haemodialysis. Problems with charcoal haemoperfusion have centred around platelet aggregation and hypertension, and new carbon preparations with a variety of diffe...

journal_title：Gut

authors： Williams R

更新日期：1978-06-01 00:00:00

abstract：:The major end products of fermentation, short chain fatty acids (acetate, propionate, butyrate) were measured in portal and peripheral venous blood after the caecal instillation of lactulose at surgery in patients undergoing elective cholecystectomy. Blood samples for short chain fatty acid measurement were taken befo...

journal_title：Gut

authors： Peters SG,Pomare EW,Fisher CA

更新日期：1992-09-01 00:00:00

abstract：:Histochemical enzymatic studies were performed on 30 freshly resected large bowel carcinomas, 30 samples of normal colonic epithelium, and six samples of the histologically normal epithelium (so-called transitional epithelium) immediately adjacent to a carcinoma. Five enzymes were studied: nicotine adenine dinucleotid...

journal_title：Gut

authors： Marsden JR,Dawson IM

更新日期：1974-10-01 00:00:00

abstract：BACKGROUND:In liver regeneration after portal branch ligation we previously showed that early cellular changes are observed in both the proliferating and atrophying liver lobes. They are therefore not indicative of future proliferative response. In this study we attempted to define precisely, in the same model, the tim...

journal_title：Gut

authors： Stärkel P,Lambotte L,Sempoux C,De Saeger C,Saliez A,Maiter D,Horsmans Y

更新日期：2001-07-01 00:00:00

abstract：:This paper reports the association between severe, prolonged, watery diarrhoea and islet cell tumours of the pancreas. There appear to be significant differences between patients with these symptoms and those with the classical Zollinger-Ellison syndrome. ...

journal_title：Gut

authors： TELLING M,SMIDDY FG

更新日期：1961-03-01 00:00:00

abstract：BACKGROUND:Dyspepsia is a chronic disease with significant impact on the use of health care resources. A management strategy based on Helicobacter pylori testing has been recommended but the long term effect is unknown. AIM:To investigate the long term effect of a test and treat strategy compared with prompt endoscopy...

journal_title：Gut

authors： Lassen AT,Hallas J,Schaffalitzky de Muckadell OB

更新日期：2004-12-01 00:00:00

abstract：:There is no satisfactory biomarker yet available for predicting the likelihood of premalignant changes or carcinoma developing in Barrett's or columnar lined oesophagus. In this study we have evaluated the proliferation of squamous epithelium, columnar epithelium from columnar lined oesophagus and gastric columnar epi...

journal_title：Gut

authors： Iftikhar SY,Steele RJ,Watson S,James PD,Dilks K,Hardcastle JD

更新日期：1992-06-01 00:00:00

abstract：:By prolonged immunization of an inbred rat strain with isologous liver homogenate in Freund's complete adjuvant a low grade autoimmune ;cholangitis' with periductular fibrosis has been demonstrated. The lesion could be transferred to isogeneic animals by serial spleen cell injections and was associated with mild but v...

journal_title：Gut

authors： Maclaurin BP

更新日期：1971-06-01 00:00:00

abstract：OBJECTIVE:Conventional colonoscopy (CC) is considered the reference standard for detection of colorectal neoplasia, but it can still miss a substantial number of adenomas. The use of a transparent plastic cap may improve colonic visualisation. Cap-assisted colonoscopy (CAC) was compared with CC for adenoma detection. S...

journal_title：Gut

authors： de Wijkerslooth TR,Stoop EM,Bossuyt PM,Mathus-Vliegen EM,Dees J,Tytgat KM,van Leerdam ME,Fockens P,Kuipers EJ,Dekker E

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Gastric acid secretion is downregulated by Helicobacter pylori infection and upregulated after its eradication, but the mechanisms are still unclear. We examined the effects of H pylori eradication on the number of parietal cells and on expression of molecules functioning in acid secretion in the hu...

journal_title：Gut

authors： Osawa H,Kita H,Ohnishi H,Hoshino H,Mutoh H,Ishino Y,Watanabe E,Satoh K,Sugano K

更新日期：2006-02-01 00:00:00

abstract：:The biomechanical properties of the oesophageal wall were investigated in a rabbit model using a four electrode impedance technique. A specially designed probe with the electrodes inside a low pressure expandable insulating latex balloon was introduced in the oesophagus. Stepwise inflation and deflation was done for a...

journal_title：Gut

authors： Gregersen H,Jensen LS,Djurhuus JC

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Patients with irritable bowel syndrome (IBS) have reduced pain thresholds for rectal distension. In addition, the prevalence of sexual/physical abuse in referred IBS patients is high and is associated with greater pain reporting, poorer health status, and poorer outcome. This lead to a hypothesis that abuse ...

journal_title：Gut

authors： Ringel Y,Whitehead WE,Toner BB,Diamant NE,Hu Y,Jia H,Bangdiwala SI,Drossman DA

更新日期：2004-06-01 00:00:00

abstract：:The effect of the unconjugated bile acids, cholic, deoxycholic, chenodeoxycholic, and ursodeoxycholic acids, and of the conjugated bile acid taurocholic acid on the mucosal-to-serosal transport and tissue uptake of the naturally occurring folate derivative, 5-methyltetrahydrofolate (5-CH3H4PteGlu) was examined in ever...

journal_title：Gut

authors： Said HM,Hollander D,Strum WB

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVE:The transcriptional profile of gastric epithelial cell lines cocultured with Helicobacter pylori and the global gene expression of whole gastric mucosa has been described previously. We aimed to overcome limitations of previous studies by determining the effects of H pylori eradication on the transcriptome of...

journal_title：Gut

authors： Resnick MB,Sabo E,Meitner PA,Kim SS,Cho Y,Kim HK,Tavares R,Moss SF

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:Non-coeliac gluten sensitivity (NCGS) is characterised by intestinal and extraintestinal symptoms related to the ingestion of gluten-containing foods, in the absence of coeliac disease (CD) and wheat allergy. No biomarkers are available to diagnose NCGS and the gold standard double-blind placebo-controlled gl...

journal_title：Gut

authors： Barbaro MR,Cremon C,Morselli-Labate AM,Di Sabatino A,Giuffrida P,Corazza GR,Di Stefano M,Caio G,Latella G,Ciacci C,Fuschi D,Mastroroberto M,Bellacosa L,Stanghellini V,Volta U,Barbara G

更新日期：2020-11-01 00:00:00

abstract：:Although changes in T lymphocyte subset distribution in the peripheral blood of patients infected with human immunodeficiency virus (HIV) are well defined it is not known whether these changes reflect changes in lymphoid compartments clearly involved in HIV related disease like the intestinal mucosa. This study analys...

journal_title：Gut

authors： Schneider T,Jahn HU,Schmidt W,Riecken EO,Zeitz M,Ullrich R

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Recent reports have described a modulating influence of nitric oxide (NO) on intestinal mucosal permeability and have implicated a role for mast cells in this NO mediated process. AIMS:To assess further the contribution of mast cells to the mucosal permeability changes elicited by the NO synthase (NOS) inhi...

journal_title：Gut

authors： Komatsu S,Grisham MB,Russell JM,Granger DN

更新日期：1997-11-01 00:00:00

abstract：:Although colorectal cancer (CRC) is a common cause of cancer-related death, it is fortunately amenable to screening with faecal tests for occult blood and endoscopic tests. Despite the evidence for the efficacy of guaiac-based faecal occult blood tests (gFOBT), they have not been popular with primary care providers in...

journal_title：Gut

authors： Tinmouth J,Lansdorp-Vogelaar I,Allison JE

更新日期：2015-08-01 00:00:00

abstract：:The rate of gastric emptying of two antacids, magaldrate and Maalox, was investigated using scintigraphy. Successful labelling of the antacids was carried out with 99mTc. The stability of the 99mTc-labelled antacids was satisfactory and there was no difference in antacid capacity between the labelled and unlabelled an...

journal_title：Gut

authors： Monés J,Carrió I,Roca M,Estorch M,Calabuig R,Sainz S,Martinez-Duncker C,Vilardell F

更新日期：1991-02-01 00:00:00

abstract：:Sera from patients with Crohn's disease have been reported to show positive immunofluorescence with lymph nodes of nude mice primed with a filtrate of intestinal tissue affected with Crohn's disease. An indirect immunofluorescence assay was used to test sera of 63 unrelated patients with Crohn's disease, 21 with ulcer...

journal_title：Gut

authors： Pena AS,Kuiper I,Walvoort HC,Verspaget HW,Weterman IT,Ruitenberg EJ,Das KM

更新日期：1986-12-01 00:00:00

abstract：:In a search for past or present infection with herpes viruses, serum antibody titres to herpes simplex type 1 virus, cytomegalovirus, and varicella-zoster virus were measured by complement fixation test in 58 patients with achalasia. Serum was also taken from 40 age and sex matched patients without oesophageal symptom...

journal_title：Gut

authors： Robertson CS,Martin BA,Atkinson M

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVE:In treating patients with inflammatory bowel disease (IBD), how concomitant medications influence the response to infliximab is largely unexplored. We aim to evaluate whether proton pump inhibitors (PPIs) affect the response to infliximab therapy in patients with IBD. DESIGN:Patient-level data of adult patie...

journal_title：Gut

authors： Lu TX,Dapas M,Lin E,Peters T,Sakuraba A

更新日期：2020-12-17 00:00:00

abstract：:Water and electrolyte balance has been studied in 39 patients with a permanent ileostomy, who had had a proctocolectomy for ulcerative colitis. The findings have been compared with those in 39 healthy subjects who were matched for age and sex. The ileostomists were found to lose excessive quantities of water and sodiu...

journal_title：Gut

authors： Kennedy HJ,Al-Dujaili EA,Edwards CR,Truelove SC

更新日期：1983-08-01 00:00:00

abstract：:The aim of this study is to assess the value of jejunal manometry in the diagnosis of subacute mechanical obstruction distal to the proximal small bowel. In a retrospective review of 850 manometric tracings carried out in patients with unexplained nausea, vomiting, abdominal pain or altered bowel movements, 16 tracing...

journal_title：Gut

authors： Camilleri M

更新日期：1989-04-01 00:00:00