Abstract:
OBJECTIVES:Host modifying factors, such as genetic predisposition, may increase severity of periodontitis. Genetic polymorphisms in interleukin-4 (IL-4) genes seem to influence host response to microbial challenge. Two IL-4 polymorphisms were found in association with asthma and atopy, and later with aggressive periodontitis in Caucasians. There seems to be a trend for racial differences regarding polymorphisms. Therefore, this study aimed to evaluate if these IL-4 polymorphisms were associated with periodontal disease in a Brazilian population of African heritage. METHODS:Sixty patients were divided into two groups: periodontitis group (n = 30) and control group (n = 30) Blood samples were taken and genomic DNA was amplified by polymerase chain reaction (PCR). Identification of 70 bp repeat polymorphism in intron 2 and in the -590 position of the promoter region was performed through PCR-RFLP and electrophoresis in agarose gel. RESULTS:No significant differences were found in the genotype frequency of the polymorphisms between control and periodontitis group. Chi square test and Mann-Whitney test were used for statistical analysis. CONCLUSIONS:We concluded that the studied IL-4 polymorphisms were not related to periodontal disease susceptibility in this African-American Brazilian population.
journal_name
J Dentjournal_title
Journal of dentistryauthors
Pontes CC,Gonzales JR,Novaes AB Jr,Taba Júnior M,Grisi MF,Michel J,Meyle J,de Souza SLdoi
10.1016/j.jdent.2003.11.004keywords:
subject
Has Abstractpub_date
2004-03-01 00:00:00pages
241-6issue
3eissn
0300-5712issn
1879-176Xpii
S030057120300191Xjournal_volume
32pub_type
杂志文章abstract:OBJECTIVES:A low pH environment is created by cariogenic bacteria. This study was aimed to measure pH of carious lesions intraorally using a micro-pH sensor, and assess predominant acid-producing cariogens by qPCR to differentiate caries activities. METHODS:103 dentine lesions classified as active or arrested caries b...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2011.12.013
更新日期:2012-03-01 00:00:00
abstract:UNLABELLED:Soy beverages are water extracts of whole soybeans and are often promoted as a healthy alternative to bovine milk. Little analysis has been carried out to determine the effects of soy beverages on oral health, especially their potential acidogenicity. OBJECTIVES:The aim of this study was to determine the po...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2012.05.004
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:To evaluate the efficacy of different bleaching systems on artificially created stained-remineralized caries lesions; and to assess the susceptibility of the bleached lesions to further demineralization. METHODS:Human enamel specimens were sectioned, polished, demineralized, and randomly divided into six gr...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2018.12.008
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVES:The present study compared the efficacies of the self-etching Teeth Primer (TP: 4-META), and the etchants Red Activator (RA; 65% phosphoric acid) and Green Activator (GA; 10% citric acid with 3% ferric chloride), for bonding to enamel and dentine of human primary and permanent teeth, when used with 4-META/MM...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2014.01.007
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of application method on immediate and 6-month resin-dentin microtensile bond strength (microTBS) and nanoleakage (NL) of three one-step self-etch adhesives systems (Clearfil S(3) Bond (S3), Xeno III (XE) and Adper Prompt L-Pop (AD)). METHODS:The oclusal enamel of 30 human molar was r...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2008.09.010
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:To investigate the effect of impregnation of poly(ethyl methacrylate) and tetrahydro-furfuryl methacrylate (PEM/THFM) polymeric delivery system with chlorhexidine or fluconazole on its shear bond strength (SBS) and water sorption. METHODS:For SBS testing, 16 PEM/THFM discs impregnated with chlorhexidine (CH...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2012.04.027
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:Several studies have made comparisons in the dimensional accuracy of different elastomeric impression materials. Most have used two-dimensional measuring devices, which neglect to account for the dimensional changes that exist along a three-dimensional surface. PURPOSE:The aim of this study was to compare th...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2004.07.005
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to identify factors influencing the selection of restorative materials. METHODS:In 1992, a random sample of Finnish dentists working in the public and private health care sectors were asked to provide information on restorative treatments during a given period. The study material co...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/0300-5712(95)00070-4
更新日期:1996-07-01 00:00:00
abstract:OBJECTIVES:Root canal treatment forms an essential part of general dental practice. Sodium hypochlorite (NaOCl) is the most commonly used irrigant in endodontics due to its ability to dissolve organic soft tissues in the root canal system and its action as a potent antimicrobial agent. Although NaOCl accidents created ...
journal_title:Journal of dentistry
pub_type: 杂志文章,评审
doi:10.1016/j.jdent.2013.08.012
更新日期:2013-11-01 00:00:00
abstract::OBJECTIVES.: To compare the safety and plaque removal efficacy of two oscillating/rotating/pulsating toothbrushes (Oral-B ProfessionalCaretrade mark 7000 [PC 7000] and Oral-B 3D Excel [3DE]) and a high-frequency toothbrush (Sonicare(R) Advance, Philips Oral Healthcare; SA) in a single-use, examiner-blind, three period...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
abstract:INTRODUCTION:C. tropicalis and C. krusei have emerged as virulent species causing oral infections. Both have developed resistance to commonly prescribed azole antifungal agents. OBJECTIVE:The study aimed to determine the effect of mouth rinses containing chlorhexidine digluconate (CHX), cetylpyridinium chloride (CPC) ...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2012.04.003
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to investigate the corrosion resistance of the prototype iron-platinum (FePt) magnets and non-encapsulated neodymium-iron-boron (NdFeB) magnets in three different pH environments. METHODS:The corrosion resistance of the magnets was studied using a corrosion indicator, the bre...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2004.02.007
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVES:Recently, a novel device to generate dental plaque in situ on a removable human enamel surface was described. The device permitted the recovery of plaque intact and undisturbed on its enamel substrate. The aim of this investigation was to determine the utility and robustness of this model for analysis of the...
journal_title:Journal of dentistry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0300-5712(01)00033-1
更新日期:2001-08-01 00:00:00
abstract:OBJECTIVES:Some studies have been conducted to evaluate the effect of different topical fluoride regimens on the remineralization of initial carious lesions. This study was conducted to compare the effects of 3 topical fluoride treatments on the surface microhardness, fluoride uptake, and fluorescence lesion area in en...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2009.10.002
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVES:To measure aspects of fizzy drink consumption in a social environment to inform the development of a laboratory testing regime. METHODS:This was an observational study in which participants were invited to attend one of four pizza and soft drink parties. All such foods and drinks were served in an air condi...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2015.08.008
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVES:This study investigated the in-vitro performance and fracture force of anterior implant-supported tooth-coloured fixed dental prosthesis (FDPs). Different material types with varying flexural strength and modulus of elasticity were compared with screw-retained or bonded application. MATERIALS AND METHODS:Id...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2020.103326
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVES:Following tooth pulp exposure, pulpal repair is accomplished by dentine bridge secretion by odontoblast-like cells. However, little information is available about the hierarchy of variables, which influence odontoblast-like cell numbers. The purpose of this study was to examine correlations between pulp capp...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(02)00024-6
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVES:Three strength tests (compressive, three point flexure and biaxial) were performed on three glass ionomer (GI) restoratives to assess the most appropriate methodology in terms of validity and reliability. The influence of mixing induced variability on the data sets generated were eliminated by using encapsul...
journal_title:Journal of dentistry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jdent.2011.12.002
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVES:To determine the visual 50:50% acceptability thresholds for lightness, chroma and hue for dental ceramics using CIEDE2000(K(L):K(C):K(H)) formula, and to evaluate the formula performance using different parametric factors. METHODS:A 30-observer panel evaluated three subsets of ceramic samples: lightness sub...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2011.09.007
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVES:To assess the accuracy of a novel, non-invasive method for determining the axis of rotation of articulated dental study casts. METHOD:A 3D structured light scanner was constructed using a projector and two CMOS cameras. Dental stone casts were arbitrarily mounted on an average value articulator. With the te...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2013.11.019
更新日期:2014-02-01 00:00:00
abstract::Evidence exists that plasma F- concentrations of 1.0 part/10(6) are nephrotoxic and that much lower levels disturb enamel mineralization. Ingested F(-)-containing gels, tablets and toothpastes all raise plasma F- levels significantly, as does prolonged exposure to fluorine-containing anaesthetic gases. There is, there...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/0300-5712(90)90254-c
更新日期:1990-02-01 00:00:00
abstract:OBJECTIVES:The aetiology of orofacial pain (OFP) is not well understood. We aimed to determine the relationship between OFP and local mechanical factors in an unselected general population sample. METHODS:A cross-sectional population-based survey was conducted in the United Kingdom, involving 2504 participants (adjust...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(03)00108-8
更新日期:2003-11-01 00:00:00
abstract:INTRODUCTION:Tooth surface loss (TSL) is an increasingly recognised problem. We are therefore seeing an increase in the number and complexity of in vitro studies investigating factors that modify effects at the tooth surface. AIM:The aim of this paper is to provide a narrative review that illustrates the more commonly...
journal_title:Journal of dentistry
pub_type: 杂志文章,评审
doi:10.1016/j.jdent.2010.01.002
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the novel mesocellular siliceous foams (MCF) containing CaCO3 nanoparticles (denoted as CMCF) combined with phosphoric acid could occlude dentinal tubules through the formation of biomimetic crystal barrier. METHODS:Ultrastructures of MCF and CMCF were examined by tr...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2019.02.007
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVES:This study was performed to determine the compositions of commercial temporary restorative resins and to evaluate the leachability of plasticizer and residual monomer from them. METHODS:The chemicals in four commercial temporary restorative resins (Dura Seal, Fit Seal, Plast Seal Quick, and Poly Seal) were ...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2003.12.004
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVES:The purpose of the study was to evaluate gloss and color changes of resin composites after exposure to different bleaching agents. METHODS:Products used, were: Nite White ACP (10% carbamide peroxide gel), Crest Classic and Supreme Whitestrip (6.5% and 14% hydrogen peroxide strips, accordingly). A hybrid (He...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2010.06.006
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:To measure the tooth whitening effects delivered immediately after brushing with silica-based toothpastes containing blue covarine in vitro and in vivo. METHODS:Salivary pellicle coated human extracted teeth were brushed with either a slurry of a toothpaste containing blue covarine (BC), a formulation conta...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2017.10.014
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVES:To determine the phenotypic and molecular characteristics of Enterococcus faecalis recovered from primary endodontic infections in Brazilian patients. METHODS:Twenty isolates of E. faecalis recovered from 43 Brazilian patients with primary endodontic infections were identified by biochemical profiling (API2...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2013.07.004
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVES:This study investigated whether novel liposome formulations loaded with transforming growth factor β1 (TGF-β1) could promote the odontogenic differentiation of human dental pulp stem cells (hDPSCs) for dentine-pulp regeneration. METHODS:0-100 ng/mL of liposomal TGF-β1 was prepared using the thin-film hydrat...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2020.103501
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVES:The objectives of this study were to investigate: (1) the antibacterial activity of two antibacterial monomers, dimethylaminododecyl methacrylate (DMADDM) and dimethylammoniumethyl dimethacrylate (DMAEDM), against eight different species of oral pathogens for the first time; (2) the cytotoxicity of DMAEDM an...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2013.07.006
更新日期:2013-10-01 00:00:00