Abstract:
OBJECTIVES:Recently, a novel device to generate dental plaque in situ on a removable human enamel surface was described. The device permitted the recovery of plaque intact and undisturbed on its enamel substrate. The aim of this investigation was to determine the utility and robustness of this model for analysis of the effects of therapeutics on both enamel remineralisation and on the overlying biofilm composition. METHODS:Enamel slices were taken from extracted sound human teeth, sterilised and a 'flat' area ground on each slice. An artificial lesion was formed within this area using acidified gel and the hardness of the enamel within the area of the lesion was determined at five sites using a 'Vickers' indenter. A nylon ring was then attached over the area of the lesion with cyanoacrylate and the excess enamel removed to form the completed device. Two devices were attached to the upper molars of 22 volunteers. Each volunteer was randomly assigned to receive either a fluoride containing (1500 ppm) or a fluoride free dentifrice. The devices were retained for a 4 week period whilst undertaking normal oral hygiene. All procedures were conducted according to GCP. After a 2 week break, the volunteers were fitted with two further devices, given dentifrice of the alternate type and the procedure repeated. Plaque from each device was harvested for microbiological analyses and the enamel subject to microhardness measurement. Then for each device the change in microhardness of the enamel within the lesion over the 4 week period was calculated. RESULTS:There were no significant differences in viable counts of total aerobic bacteria, mutans streptococci or lactobacilli, nor in acidic, aciduric or arginolytic populations in plaque from patients using the two different dentifrices. However, devices subjected to the fluoride containing dentifrice demonstrated a significantly greater increase in microhardness of the enamel (P<0.025). CONCLUSIONS:These results suggest that the novel in situ device is capable of measuring the effect of 1500 ppm fluoride on remineralisation of carious enamel over a 4 week period and is also well suited to determining concomitant effects on plaque ecology.
journal_name
J Dentjournal_title
Journal of dentistryauthors
Shore RC,Kirkham J,Devine D,Marsh P,Nattress B,Robinson Cdoi
10.1016/s0300-5712(01)00033-1keywords:
subject
Has Abstractpub_date
2001-08-01 00:00:00pages
415-9issue
6eissn
0300-5712issn
1879-176Xpii
S0300-5712(01)00033-1journal_volume
29pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVES:The objectives of this study were to: (1) develop a novel multifunctional composite with nanoparticles of silver (NAg), 2-methacryloyloxyethyl phosphorylcholine (MPC), dimethylaminohexadecyl methacrylate (DMAHDM) and nanoparticles of amorphous calcium phosphate (NACP); and (2) investigate biofilm-inhibition ...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2018.12.001
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to investigate the effect of tooth age on colour adjustment potential of resin composite restorations in human teeth. METHODS:Twenty extracted human premolars with an A2 shade, extracted for orthodontic reasons from younger patients (20-28yrs) (younger teeth) and periodontal re...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2014.09.007
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVES:To validate a new questionnaire for evaluating the 'Oral aesthetic-related quality of life (OARQoL)' of prosthetically restored patients. 'OARQoL' assesses the impact of the self-perceived dental aesthetics on patients' well-being. METHODS:The 'Quality of Life associated with Dental Aesthetic Satisfaction (...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2015.08.010
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to illustrate the graded proper properties of enamel from the outer (near occlusal surface) to the inner region (near enamel-dentine junction) in a cross-sectioned surface and discuss how natural design achieve the graded functions. METHODS:Nanoindentation, Raman spectroscopes, and S...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2009.03.019
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:To investigate whether bleaching prior to placement of a composite veneer had an effect on the final shade of the restoration and whether this was affected by the thickness or shade of the veneer. METHODS:Twenty bovine teeth were collected, sectioned and divided into two groups. One group was the non-bleache...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2008.04.004
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVES:Sleep bruxism (SB), characterized by repetitive jaw-muscle activity during sleep, is often suggested as a cause of temporomandibular disorders (TMD), orofacial pain, and headache. This study aimed to challenge the relationship between jaw-muscle electromyographic (EMG) activity during sleep and jaw muscle sy...
journal_title:Journal of dentistry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jdent.2019.01.013
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to determine whether conventional black tea and a herbal tea were capable of eroding dental enamel. A further aim was to investigate whether herbal tea of the type tested eroded dental hard tissues to a greater or lesser extent than conventional black tea. METHODS:Three groups of 2...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(01)00044-6
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVES:To examine the amount of heterogeneity in patients' preferences for dental care, what factors affect their preferences, and how much they would be willing to pay for improvement in specific dental care attributes. METHODS:A discrete choice experiment (DCE) was used to elicit patients' preferences. Three alt...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2017.12.005
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:This study evaluated the effects of surface preparation and the application time of adhesives on the resin-dentine bond strengths with universal adhesives. METHODS:Sixty molars were cut to exposed mid-coronal dentine and divided into 12 groups (n=5) based on three factors; (1) adhesive: G-Premio Bond (GP, GC...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2016.02.001
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVES:Acrylic resins, used in the manufacturing of different types of intra-oral prostheses, are vulnerable to colonisation by microorganisms which potentially endanger the general health of the prostheses, wearers. The aim of this study was to investigate the influence of a novel coating (Parylene) on surface rou...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2013.06.011
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:This randomised, examiner-blind parallel group study was designed to evaluate the safety and efficacy of a rechargeable oscillating/pulsating toothbrush (Oral-B ProfessionalCare 7000, Oral-B Laboratories; PC 7000) and a battery-operated toothbrush (Crest SpinBrush Pro, Procter & Gamble Company; SBP) in the re...
journal_title:Journal of dentistry
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2005-06-01 00:00:00
abstract:OBJECTIVES:The light intensity of curing lights used in private dental offices was measured using commercial curing and heat radiometers and related to uniformity of cure depth of standardized composite specimens. METHODS:The intensity of 130 curing light from 107 dental offices was measured with curing and heat radio...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(98)00052-9
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVES:The objectives of this study were to investigate: (1) the antibacterial activity of two antibacterial monomers, dimethylaminododecyl methacrylate (DMADDM) and dimethylammoniumethyl dimethacrylate (DMAEDM), against eight different species of oral pathogens for the first time; (2) the cytotoxicity of DMAEDM an...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2013.07.006
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare the fracture strength of three techniques used to re-attach tooth fragments in sound and endodontically treated fractured teeth with or without fiber post placement. MATERIAL AND METHODS:Ninety human lower incisors were randomly divided into three groups of 30 teeth each...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2008.01.001
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVES:This study evaluated the effect of a chromium interlayer deposited by electroplating on the adhesion between titanium and porcelain by means of strain energy release rate (G-value (J/m(2)) or interfacial toughness). METHODS:Seventy rectangular specimens of commercially pure titanium (CP Ti) plates grade II ...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2010.05.003
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:The aim of this investigation was to compare the clinical survival rate of all-ceramic FPDs with failures during in vitro simulation. METHODS:40 anterior FPDs were manufactured from lithiumdisilicate ceramic and alumina-oxide ceramic. The FPDs were adhesively bonded to human teeth and artificially aged to in...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2008.09.001
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVES:To compare the accuracies of 4 laboratory scanners using a new custom-made block for complete-arch implant rehabilitation. MATERIALS AND METHODS:A block comprised 4 cylinders, with 2 in the anterior (0° angulation) and 2 in the posterior region (45° distal angulation) (Experimental group) and a standard blo...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2020.103476
更新日期:2020-11-01 00:00:00
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journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2009.02.006
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of hydrothermal aging (H), mechanical cycling (M), and the combination of hydrothermal plus mechanical cycling (H+M) on biaxial flexural strength (BFS) and microstructure of two monolithic zirconias, indicated for anterior (AMZ) or posterior restorations (PMZ) and a conventional zircon...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2017.05.021
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:The intent of this project was to evaluate the efficiency of three commercial amalgam separators based on mercury and particle removal. METHODS:Dental wastewater samples were collected from a 54-chair dental clinic and a one chair private dental office. Atomic absorption spectrometry was used to measure merc...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(02)00067-2
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:To investigate the potential use of swept-source optical coherence tomography (SS-OCT) as a new tool to evaluate marginal adaptation of composite restorations in class I cavities. METHODS:Round-shaped class I cavities (3mm diameter × 1.5mm depth) were prepared on buccal enamel of bovine teeth with cavity fl...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2011.01.011
更新日期:2011-04-01 00:00:00
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journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2009.01.003
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis, derived from a previous short-term (7-day) assessment, that the absence of conventional pulp protection is not responsible for long-term pulp complications of composite resin restorations with self-etching adhesives. METHODS:All 150 patients who received the restorations with self-etc...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2007.02.005
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVES:The study aims at demonstrating the feasibility of a novel type of coupling-agent-free resin composite based on nano-porous fillers. METHODS:The fillers were obtained by ball-milling anodic alumina membranes. Composites were prepared with standard resin at maximum loading of 50% by weight. The resin matrix ...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2013.12.001
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the risk factors associated with noncarious cervical lesions (NCCLs), cervical dentin hypersensitivity (CDH), and gingival recession (GR), besides the relationship among these conditions in a specific Brazilian sample population. METHODS:185 patients who attended the "A...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2018.06.017
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to investigate the effect of silver diamine fluoride (SDF) therapy on the oral health-related quality of life (OHRQoL) of preschool children and their families in a school-based setting. METHODS:A prospective study was conducted in six kindergartens in Hong Kong. Parents of the chil...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2018.12.004
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of shading technique and thickness on the color stability and translucency of translucent zirconia after coffee thermocycling. METHODS:Specimens in different thicknesses (1; 1.5; 2 mm) (n = 4 for each thickness) were sectioned from translucent preshaded zirconia (Pre) and externally sh...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2018.03.011
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of Halloysite® aluminosilicate clay nanotubes (HNTs) addition on selected physical, mechanical, and biological properties of experimental adhesive resins. METHODS:Experimental dentin adhesive resins were prepared by mixing Bis-GMA, TEGDMA, HEMA (50/25/25wt.%), and photo-initiators....
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2015.08.014
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:The purpose of this paper is to review current knowledge and technologies for tooth remineralisation. DATA SOURCES:The literature was searched using the "Scopus" and "Web of Knowledge" database from the year 1971, with principal key words of *miner*, teeth and enamel. Language was restricted to English. Orig...
journal_title:Journal of dentistry
pub_type: 杂志文章,评审
doi:10.1016/S0300-5712(14)50003-6
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVES:This study investigated the effects of the surface conditioning of nano-zirconia fillers with 10-methacryloyloxydecyl dihydrogen phosphate (MDP) and dipentaerythritol penta-acrylate phosphate (PENTA) on the degree of conversion and mechanical properties of Bis-GMA- and UDMA-based resin composites containing ...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2020.103306
更新日期:2020-03-01 00:00:00