当前位置： SCI文献检索 > NEUROSCIENCE期刊下所有文献 > Unilateral hindpaw inflammation produces a bilateral increase in NADPH-diaphorase histochemical staining in the rat lumbar spinal cord.

Unilateral hindpaw inflammation produces a bilateral increase in NADPH-diaphorase histochemical staining in the rat lumbar spinal cord.

Abstract：

:Tissue injury results in several changes in spinal cord neurons that contribute to hyperalgesia arising from the injured tissue. In models of unilateral hindpaw inflammation, changes in the neurochemistry and electrophysiology of dorsal horn neurons ipsilateral, and to a much lesser extent contralateral, to the inflamed paw have been reported. For example, the excitability of dorsal horn neurons increases, receptive field size increases, and the content of various proteins and neuropeptides in the dorsal horn (e.g. FOS, dynorphin, enkephalin) are affected following peripheral inflammatory insult. These changes are typically interpreted on the basis of their relevance to nociception.

journal_name

Neuroscience

journal_title

Neuroscience

authors

Solodkin A,Traub RJ,Gebhart GF

doi

10.1016/0306-4522(92)90290-i

keywords:

subject

Has Abstract

pub_date

1992-12-01 00:00:00

pages

495-9

issue

3

eissn

0306-4522

issn

1873-7544

pii

0306-4522(92)90290-I

journal_volume

51

pub_type

杂志文章

相关文献

NEUROSCIENCE文献大全
  • Plasticity of tyrosine hydroxylase and vasoactive intestinal peptide messenger RNAs in visceral afferent neurons of the nodose ganglion upon axotomy-induced deafferentation.

    abstract：:The nodose ganglion contains placode-derived visceral sensory neurons of the vagus nerve. Previous study showed that axotomy-induced deafferentation reduced the number of tyrosine hydroxylase-immunoreactive and increased the number of vasoactive intestinal peptide-immunoreactive neurons in the ganglion. The present st...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(94)90555-x

    authors： Zhuo H,Sinclair C,Helke CJ

    更新日期：1994-11-01 00:00:00

  • The inhibitory effects of nicotinic antagonists on currents elicited by GABA in rat hippocampal neurons.

    abstract：:The nicotinic antagonists d-tubocurarine and trimethaphan camsylate competitively inhibit GABA-induced currents. Hexamethonium, mecamylamine and dihydro-beta-erythroidine, other nicotinic antagonists, do not affect GABA-elicited currents. The trimethaphan effect is completely reversed by a putative convulsant receptor...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(95)00011-7

    authors： Wotring VE,Yoon KW

    更新日期：1995-07-01 00:00:00

  • Mouse spinal cord compression injury is reduced by either activation of the adenosine A2A receptor on bone marrow-derived cells or deletion of the A2A receptor on non-bone marrow-derived cells.

    abstract：:Activation of the adenosine A(2A) receptor (A(2A)R) at the time of reperfusion has been shown to reduce ischemia-reperfusion injury in peripheral tissues and spinal cord. In this study we show that treating mice with the A(2A)R agonist, 4-{3-[6-amino-9-(5-cyclopropylcarbamoyl-3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-pu...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2006.05.014

    authors： Li Y,Oskouian RJ,Day YJ,Rieger JM,Liu L,Kern JA,Linden J

    更新日期：2006-09-15 00:00:00

  • Examination of the role of the pedunculopontine tegmental nucleus in radial maze tasks with or without a delay.

    abstract：:Two radial maze tasks, random foraging and delayed spatial win-shift, have been used to investigate, in rats, the functions and inter-relationships of structures connected through the corticostriatal loops, such as the prelimbic cortex, nucleus accumbens, ventral pallidum and mediodorsal thalamus. The random foraging ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(02)00108-2

    authors： Keating GL,Winn P

    更新日期：2002-01-01 00:00:00

  • Quantitative morphology of physiologically identified and intracellularly labeled neurons from the guinea-pig laterodorsal tegmental nucleus in vitro.

    abstract：:Mesopontine cholinergic neurons have been implicated in the initiation and maintenance of rapid eye movement sleep via their efferent connections to the thalamus and the medial pontine reticular formation. As a first step toward understanding how these modulatory neurons integrate synaptic input, we have investigated ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(96)00139-x

    authors： Surkis A,Taylor B,Peskin CS,Leonard CS

    更新日期：1996-09-01 00:00:00

  • Dopamine autoreceptor regulation of release and uptake in mouse brain slices in the absence of D(3) receptors.

    abstract：:The effects of the dopamine D(3) receptor, a putative autoreceptor, have been investigated by comparing behavioral and neurochemical properties of wild-type mice and mice with a genetic deletion of the D(3) receptor. The D(3) knock-out mice were modestly hyper-responsive to a novel environment relative to wild-type mi...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(02)00067-2

    authors： Joseph JD,Wang YM,Miles PR,Budygin EA,Picetti R,Gainetdinov RR,Caron MG,Wightman RM

    更新日期：2002-01-01 00:00:00

  • Rescue and regeneration of injured peripheral nerve axons by intrathecal insulin.

    abstract：:Insulin peptide, acting through tyrosine kinase receptor pathways, contributes to nerve development or repair. In this work, we examined the direction, impact and repertoire of insulin signaling in vivo during peripheral nerve regeneration in rats. First, we demonstrated that insulin receptor is expressed on lumbar do...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2005.11.065

    authors： Toth C,Brussee V,Martinez JA,McDonald D,Cunningham FA,Zochodne DW

    更新日期：2006-05-12 00:00:00

  • NK1-tachykinin receptors and prolonged, stimulus-evoked alterations in the excitability of withdrawal reflexes in the decerebrated and spinalized rabbit.

    abstract：:Intense natural or electrical stimulation of afferents from the toes or the heel results in prolonged changes in the excitability of the heel withdrawal reflex pathway in the rabbit. This study has investigated the roles played by tachykinin NK1 receptors in mediating these effects. Reflexes were evoked by electrical ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(94)00608-8

    authors： Houghton AK,Clarke RW

    更新日期：1995-06-01 00:00:00

  • Neonatal lesions of the entorhinal cortex induce long-term changes of limbic brain regions and maze learning deficits in adult rats.

    abstract：:We here investigated the effects of neonatal lesions of the entorhinal cortex (EC) in rats on maze learning and on structural alterations of its main projection region, the hippocampus, as well as other regions with anatomical connections to the EC that are involved in maze learning. Since early brain damage is consid...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2008.03.017

    authors： Harich S,Kinfe T,Koch M,Schwabe K

    更新日期：2008-06-02 00:00:00

  • Transneuronal labeling in hamster brainstem following lingual injections with herpes simplex virus-1.

    abstract：:Brainstem projections to hypoglossal motoneurons innervating the intrinsic and extrinsic muscles of the tongue were determined using the transneuronal transfer of Herpes simplex virus-1. Injections of Herpes simplex virus-1 into the intrinsic muscles of the anterior tongue, the geniohyoid and styloglossus muscles each...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(95)00203-u

    authors： Travers JB,Montgomery N,Sheridan J

    更新日期：1995-10-01 00:00:00

  • Control of rat hypothalamic pro-opiomelanocortin neurons by a circadian clock that is entrained by the daily light-off signal.

    abstract：:Previous studies have clearly demonstrated that the immediate-early gene, c-fos can regulate, through its protein product Fos, the expression of the pro-opiomelanocortin gene. In the present study, immunohistochemistry for Fos and beta-endorphin was used to assess the basal activity of hypothalamic pro-opiomelanocorti...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(99)00208-0

    authors： Jamali KA,Tramu G

    更新日期：1999-01-01 00:00:00

  • Dysfunction of fronto-limbic brain circuitry in depression.

    abstract：BACKGROUND:depression is characterized by a stable negative bias toward emotional stimuli. This bias is associated with abnormal activities in emotion-processing regions (such as the amygdala) and cognitive-control regions (such as the dorsolateral prefrontal cortex [DLPFC]). However, it remains unclear whether the emo...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2011.10.053

    authors： Liao C,Feng Z,Zhou D,Dai Q,Xie B,Ji B,Wang X,Wang X

    更新日期：2012-01-10 00:00:00

  • Interneurons transiently express the ERG K+ channels during development of mouse spinal networks in vitro.

    abstract：:During spinal cord maturation neuronal excitability gradually differentiates to meet different functional demands. Spontaneous activity, appearing early during spinal development, is regulated by the expression pattern of ion channels in individual neurons. While emerging excitability of embryonic motoneurons has been...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2005.06.040

    authors： Furlan F,Guasti L,Avossa D,Becchetti A,Cilia E,Ballerini L,Arcangeli A

    更新日期：2005-01-01 00:00:00

  • Moderate hypoglycemia aggravates effects of hypoxia in hippocampal slices from diabetic rats.

    abstract：:We recorded the effects of hypoxia combined with relative hypoglycemia on pre- and post-synaptic potentials in the CA1 area of slices from 4-month-old control and diabetic (streptozotocin-treated) Wistar rats. In experiments on slices kept in 10 or 4 mM glucose (at 33 degrees C), hypoxia was applied until the pre-syna...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(02)00154-9

    authors： Tekkök SB,Godfraind JM,Krnjević K

    更新日期：2002-01-01 00:00:00

  • Can prepared anticipatory postural adjustments be updated by proprioception?

    abstract：:Stepping over an obstacle is preceded by a center of pressure (CoP) shift, termed anticipatory postural adjustments (APAs). It provides an acceleration of the center of mass forward and laterally prior to step initiation. The APAs are characterized in the lateral direction by a force exerted by the moving leg onto the...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2008.06.021

    authors： Ruget H,Blouin J,Teasdale N,Mouchnino L

    更新日期：2008-08-26 00:00:00

  • Long-term potentiation during whole-cell recording in rat hippocampal slices.

    abstract：:Factors involved in the production of long-term potentiation in the CA1 region of rat hippocampal slices were examined using whole-cell voltage clamp recordings. The pairing of postsynaptic membrane depolarization with tetanic stimulation produced a reliable long-lasting enhancement of synaptic currents provided that ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(93)90282-k

    authors： Kato K,Clifford DB,Zorumski CF

    更新日期：1993-03-01 00:00:00

  • Effects of Intramuscular Heating-needle Stimulation in Controlling Adjuvant-induced Muscle Nociception in Rats: Differential Roles of Thalamic Purinergic P2X3 Receptors.

    abstract：:Here we investigated effects of intramuscular (i.m.) heating-needle stimulation on persistent muscle nociception evoked by i.m. injection of different doses (50-200 µl) of complete Freund's adjuvant (CFA) in rats. Paw withdrawal reflexes evoked by noxious mechanical and heat stimulation as well as hind limb swelling w...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2020.02.039

    authors： Lei J,Ye G,Pertovaara A,You HJ

    更新日期：2020-05-01 00:00:00

  • Epileptiform activity induced by pilocarpine in the rat hippocampal-entorhinal slice preparation.

    abstract：:An in vitro slice preparation of combined hippocampus and entorhinal cortex from adult rats was used to study the modalities of generation and propagation, as well as the pharmacological properties of the epileptiform activity induced by the muscarinic agonist pilocarpine (10 microM). Simultaneous field potentials rec...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(95)00534-x

    authors： Nagao T,Alonso A,Avoli M

    更新日期：1996-05-01 00:00:00

  • Neurochemical changes induced by acute and chronic administration of 1,2,3,4-tetrahydroisoquinoline and salsolinol in dopaminergic structures of rat brain.

    abstract：:The finding that endogenous tetrahydroisoquinolines may be involved in the etiology of Parkinson's disease suggests that their administration may cause changes resembling those observed in parkinsonian brain. We tested, using a high-performance liquid chromatography method, how single and chronic administration of 1,2...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(99)00533-3

    authors： Antkiewicz-Michaluk L,Romañska I,Papla I,Michaluk J,Bakalarz M,Vetulani J,Krygowska-Wajs A,Szczudlik A

    更新日期：2000-01-01 00:00:00

  • The Secretome of Microglia Regulate Neural Stem Cell Function.

    abstract：:Brain injury is associated with neuroinflammation, and microglia are key players in this process. Microglia can acquire pro-inflammatory or anti-inflammatory properties, but how this affects neural stem cells (NSCs) remains controversial. Here, NSCs were grown in conditioned media collected from either non-stimulated ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2017.10.034

    authors： Osman AM,Rodhe J,Shen X,Dominguez CA,Joseph B,Blomgren K

    更新日期：2019-05-01 00:00:00

  • Brain diffusivity pattern is individual-specific information.

    abstract：:The human brain is composed of complex networks of 100 billion neurons that underlie its higher functions. The set of neural connections in the brain has recently attracted growing interest from the scientific community. It is important to identify individual differences in these neural connections to study the backgr...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2015.06.032

    authors： Takao H,Hayashi N,Ohtomo K

    更新日期：2015-08-20 00:00:00

  • Maternal High-fat Diet Programs Offspring Emotional Behavior in Adulthood.

    abstract：:Prenatal exposure to high-fat diet (HFD) might predispose offspring to develop metabolic and mental disorders later in life. Insight into the molecular and behavioral consequences of maternal HFD on offspring is sparse but may involve both neuroinflammation and a dysregulated neuroendocrine stress axis. Thus, the aim ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2018.07.014

    authors： Winther G,Elfving B,Müller HK,Lund S,Wegener G

    更新日期：2018-09-15 00:00:00

  • Hippocampal Subgranular Zone FosB Expression Is Critical for Neurogenesis and Learning.

    abstract：:Neural proliferation in the dentate gyrus (DG) is closely linked with learning and memory, but the transcriptional programming that drives adult proliferation remains incompletely understood. Our lab previously elucidated the critical role of the transcription factor ΔFosB in the dorsal hippocampus (dHPC) in learning ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2019.03.022

    authors： Manning CE,Eagle AL,Kwiatkowski CC,Achargui R,Woodworth H,Potter E,Ohnishi Y,Leinninger GM,Robison AJ

    更新日期：2019-05-15 00:00:00

  • Cannabinoid type-1 receptors in the paraventricular nucleus of the hypothalamus inhibit stimulated food intake.

    abstract：:Cannabinoid receptor type 1 (CB1)-dependent signaling in the brain is known to modulate food intake. Recent evidence has actually shown that CB1 can both inhibit and stimulate food intake in fasting/refeeding conditions, depending on the specific neuronal circuits involved. However, the exact brain sites where this bi...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2014.01.005

    authors： Soria-Gómez E,Massa F,Bellocchio L,Rueda-Orozco PE,Ciofi P,Cota D,Oliet SH,Prospéro-García O,Marsicano G

    更新日期：2014-03-28 00:00:00

  • Fentanyl increases dopamine release in rat nucleus accumbens: involvement of mesolimbic mu- and delta-2-opioid receptors.

    abstract：:The effects of the mu-receptor agonist fentanyl on extracellular levels of dopamine in rat nucleus accumbens were studied in awake animals by in vivo brain microdialysis. Fentanyl dose-dependently increased the levels of dopamine when given intravenously (microg/kg) or via a microdialysis probe placed into the ventral...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(99)00046-9

    authors： Yoshida Y,Koide S,Hirose N,Takada K,Tomiyama K,Koshikawa N,Cools AR

    更新日期：1999-01-01 00:00:00

  • Properties of solitary tract neurons receiving inputs from the sub-diaphragmatic vagus nerve.

    abstract：:Vagal afferents ascending from the gastrointestinal tract synapse on neurons in the nucleus of the solitary tract. Although these neurons constitute a significant proportion of solitary tract cells their firing behaviour and synaptic properties are not documented. Since gastrointestinal tract afferent termination site...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(99)00416-9

    authors： Paton JF,Li YW,Deuchars J,Kasparov S

    更新日期：2000-01-01 00:00:00

  • Intracellular postsynaptic cannabinoid receptors link thyrotropin-releasing hormone receptors to TRPC-like channels in thalamic paraventricular nucleus neurons.

    abstract：:In rat thalamic paraventricular nucleus of thalamus (PVT) neurons, activation of thyrotropin-releasing hormone (TRH) receptors enhances excitability via concurrent decrease in G protein-coupled inwardly-rectifying potassium (GIRK)-like and activation of transient receptor potential cation (TRPC)4/5-like cationic condu...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2015.10.015

    authors： Zhang L,Kolaj M,Renaud LP

    更新日期：2015-12-17 00:00:00

  • Development of a water-escape motivated version of the Stone T-maze for mice.

    abstract：:Mice provide a highly valuable resource for investigating learning and memory processes; however, many of the established tasks for evaluating learning and memory were developed for rats. Behaviors of mice in these tasks appear to be driven by different motivational factors, and as a result, they often do not perform ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2009.12.029

    authors： Pistell PJ,Ingram DK

    更新日期：2010-03-10 00:00:00

  • Postweaning Enriched Environment Enhances Cognitive Function and Brain-Derived Neurotrophic Factor Signaling in the Hippocampus in Maternally Separated Rats.

    abstract：:Adverse environments during early life may lead to different neurophysiological and behavioral consequences, including depression and learning and memory deficits that persist into adulthood. Previously, we demonstrated that exposure to an enriched environment during adolescence mitigates the cognitive impairment obse...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2020.09.058

    authors： Cordier JM,Aguggia JP,Danelon V,Mir FR,Rivarola MA,Mascó D

    更新日期：2021-01-15 00:00:00

  • Treadmill exercise enhances synaptic plasticity, but does not alter β-amyloid deposition in hippocampi of aged APP/PS1 transgenic mice.

    abstract：:Several studies reveal that the beneficial effects of exercise interventions are dependent on the progression of Alzheimer's disease (AD). We have previously shown that long-term treadmill exercise begun before the onset of β-amyloid (Aβ) pathology prevents the deficits of cognition and long-term potentiation (LTP) in...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2015.04.038

    authors： Zhao G,Liu HL,Zhang H,Tong XJ

    更新日期：2015-07-09 00:00:00