Abstract：
PURPOSE:To report our experience with the diagnosis and management of Familial Exudative Vitreoretinopathy (FEVR) in a predominantly older Indian population.. METHODS:This prospective interventional non-comparative case series included 38 patients of FEVR and their 23 family members. The diagnosis was established by clinical examination, fluorescein angiography and family screening. Prophylactic photocoagulation/cryotherapy or surgical treatment was done depending on the severity of the disease. RESULTS:The mean age of the patients was 23.6 years. The fundus/fluorescein angiographic findings in 116 eyes of our 61 patients (6 eyes phthisical) were as follows: forty eight (41.4%) eyes had only peripheral avascular zone, 8 (6.9%) eyes had peripheral new vessels, and 35 (30.1%) eyes had retinal detachments (RD)--10 (8.6%) exudative, 5 (4.3%) tractional and 20 (17.2%) rhegmatogenous. Prophylactic photocoagulation or cryotherapy was done in 34 eyes for retinal holes, local exudative detachments and bleeding new vessels. All the eyes retained stable vision over a mean follow-up of 16 months. Only 14 RDs were suitable for surgery: scleral buckling, vitrectomy or both. The reattachment rate was 85.7% (12 of 14) and the best-corrected visual acuity (BCVA) improved to 5/60 or better in 50% of these eyes over a 2-year follow-up. CONCLUSIONS:FEVR appears to be more common than reported. Timely diagnosis and intervention is essential in view of the lifelong progression of the disease, late exacerbations, frequent involvement of family members, and poor surgical results. A high index of suspicion, family screening and early prophylaxis are recommended to prevent avoidable blindness from this underdiagnosed disease.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Shukla D,Singh J,Sudheer G,Soman M,John RK,Ramasamy K,Perumalsamy Nkeywords:
subject
Has Abstractpub_date
2003-12-01 00:00:00pages
323-8issue
4eissn
0301-4738issn
1998-3689journal_volume
51pub_type
杂志文章abstract：:The aim of the study was to compare the central corneal thickness (CCT), intraocular pressure (IOP), and tear insulin-like growth factor-1 (IGF-1) levels of 2 patients with acromegaly before and after the surgical treatment of the disease. CCTs, IOP levels, and tear IGF-1 values showed a decrease after the treatment i...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.170984
更新日期：2015-09-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.4103/0301-4738.176028
更新日期：2015-12-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.4103/ijo.IJO_1709_20
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.73691
更新日期：2011-01-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.4103/0301-4738.49390
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_958_16
更新日期：2017-01-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.182939
更新日期：2016-04-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
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pub_type： 杂志文章
doi：10.4103/0301-4738.171505
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：1999-09-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_1839_19
更新日期：2020-11-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_507_18
更新日期：2018-11-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.4103/0301-4738.73700
更新日期：2011-01-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_166_18
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_880_16
更新日期：2017-03-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.4103/0301-4738.126178
更新日期：2014-01-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_1030_17
更新日期：2019-06-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.91337
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.4103/ijo.IJO_1077_18
更新日期：2018-12-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.4103/0301-4738.195590
更新日期：2016-11-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_1730_20
更新日期：2020-12-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2002-09-01 00:00:00
abstract：:Toric intraocular lenses (IOLs) are the procedure of choice to correct corneal astigmatism of 1 D or more in cases undergoing cataract surgery. Comprehensive literature search was performed in MEDLINE using "toric intraocular lenses," "astigmatism," and "cataract surgery" as keywords. The outcomes after toric IOL impl...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.4103/ijo.IJO_810_17
更新日期：2017-12-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：1996-09-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
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更新日期：2010-07-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：CONTEXT:There are few reports on the management of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type (MALT), which are based on the experience of a single institution, as opposed to large multicenter randomized trials. AIM:The aim of this study was to report on the clinical experience ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.81993
更新日期：2011-07-01 00:00:00
