Abstract:
:Context (Background): Imiquimod (IMQ) 5% cream is an immunomodulatory and antitumorigenic agent, which was used as a topical treatment regimen, who had periocular basal cell carcinoma (BCC). AIM:This study aims to present three cases with large BCC at the medial canthal area treated with IMQ 5% cream. MATERIALS AND METHODS:IMQ 5% cream was used in three patients with ages 45, 49, and 73 who preferred medical treatment over surgery. Following incisional biopsy IMQ cream was used once a day, 5 times a week and the patients were followed up weekly during 12 week treatment period and monthly after the clearance of the lesion. RESULTS:Erythema and erosion on the surface of the lesion, injection of conjunctiva, burning and itching sensation, epiphora and punctate keratitis were seen in all patients during the treatment period. The ophthalmic side effects could be managed by topical lubricating eye drops and the inflammatory reactions resolved within 1 month after cessation of therapy. The patients were followed up for at least 3 years without tumor recurrence and the biopsies taken from the suspected area were found to be tumor free. CONCLUSION:Surgical excision of carcinoma of the eyelid at medial canthal area can be difficult without causing damage to the lacrimal system and reconstruction of the defect may need grafts or flaps. IMQ may provide an alternative therapy to surgery in certain cases.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Karabulut GO,Kaynak P,Ozturker C,Fazil K,Ocak OB,Taskapılı Mdoi
10.4103/ijo.IJO_958_16subject
Has Abstractpub_date
2017-01-01 00:00:00pages
48-51issue
1eissn
0301-4738issn
1998-3689pii
IndianJOphthalmol_2017_65_1_48_202318journal_volume
65pub_type
杂志文章abstract:Purpose:To compare different macular thickness parameters and peripapillary retinal nerve fiber layer (RNFL) thickness between recently diagnosed cases of multiple sclerosis (MS) without optic neuropathy (ON) and healthy individuals. Methods:This cross-sectional study was performed between June 2014 and June 2015. All...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_1378_18
更新日期:2019-05-01 00:00:00
abstract:PURPOSE:To assess the suitability of Brückner test as a screening test to detect significant refractive errors in children. MATERIALS AND METHODS:A pediatric ophthalmologist prospectively observed the size and location of pupillary crescent on Brückner test as hyperopic, myopic or astigmatic. This was compared with th...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.31943
更新日期:2007-05-01 00:00:00
abstract::An observational case report of electrophysiological abnormalities in a patient with anisomyopic amblyopia as a result of unilateral extensive myelinated retinal nerve fibers (MNFs) is illustrated. The electrophysiological readings revealed an abnormal pattern electroretinogram (PERG) but normal full-field electroreti...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.98724
更新日期:2012-07-01 00:00:00
abstract:Purpose:The purpose of the study was to analyze the correlation between central field index (CFI) and activity limitation in glaucoma using glaucoma activity limitation-9 (GAL-9) questionnaire. Methods:This hospital-based, cross-sectional, noninterventional study, included 50 patients diagnosed with glaucoma, with fie...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_295_18
更新日期:2018-08-01 00:00:00
abstract:Purpose:External dacryocystorhinostomy (DCR) surgeries are cost-effective with excellent success rates. The present study was designed to compare the safety and efficacy of conventional external DCR versus external DCR using Pawar silicone implant in chronic dacryocystitis. Methods:This is a prospective, comparative, ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_1889_18
更新日期:2019-07-01 00:00:00
abstract::Anterior segment infiltration in acute myeloid leukemia (AML) presenting as hypopyon uveitis is very rare. We report this case as an uncommon presentation in a patient on remission after bone marrow transplant for AML. In addition to the hypopyon, the patient presented with "red eye" caused by ocular surface disease d...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.83621
更新日期:2011-09-01 00:00:00
abstract::Retinoblastoma is a rare malignancy of the retina seen exclusively in children. It is known to cause rapid growth inside the eye and hence treatment should be started as soon as it is diagnosed. We report a case in a five-day-old infant in whom treatment (chemotherapy) was delayed by a month due to high bilirubin leve...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.67066
更新日期:2010-09-01 00:00:00
abstract:Purpose:To compare the safety and efficacy of 25-gauge pars plana vitrectomy (PPV) with either platelet-rich plasma (PRP) or inverted internal limiting membrane (ILM) flap for the treatment of large macular hole. Methods:Pseudophakic patients with idiopathic macular holes with a minimum diameter (MD) of 600-1500 μm we...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_1357_19
更新日期:2020-05-01 00:00:00
abstract::We report the clinical details and imaging findings for a case of nondecussating retinal-fugal fiber syndrome or isolated achiasma in a 4-year-old female child. Findings included the isolated absence of optic chiasm with unremarkable rest of the optic pathway and midline structures in a child presenting clinically wit...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.171970
更新日期:2015-11-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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更新日期:2011-03-01 00:00:00
abstract:PURPOSE:To establish the safety and efficacy of simultaneous bilateral primary combined trabeculotomy-trabeculectomy for developmental glaucoma. METHODS:We studied 109 consecutive patients who underwent planned simultaneous bilateral primary combined trabeculotomy-trabeculectomy for developmental glaucoma by a single ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract::Information technology has had a tremendous impact on the outlook of our professional lives. The Internet has revolutionised the speed of access to information with touch of a button. This article discusses the various aspects of information technology which are changing and enhancing our professional lives. It provid...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:2000-09-01 00:00:00
abstract:PURPOSE:To observe the effect of prophylactic intraocular pressure (IOP)-lowering medication (brinzolamide) on IOP after ranibizumab intravitreal injections (IVIs). MATERIALS AND METHODS:This prospective case-control study included 352 eyes from 352 patients (1 eye per patient) who were treated with ranibizumab intrav...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.4103/0301-4738.195006
更新日期:2016-10-01 00:00:00
abstract::The International Association of Contact Lens Educators (IACLE) is the leading provider of educational and information resources essential to contact lens educators worldwide. The New IACLE Contact Lens Course is its most important resource, used by members around the world to teach their students, the contact lens pr...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_2065_19
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:To compare modified needle drainage (MND) with conventional drainage (CD) of subretinal fluid (SRF) as described by Schepens in surgery for primary rhegmatogenous retinal detachment. METHODS:Prospective randomised clinical trial of 80 patients undergoing scleral buckling with subretinal fluid drainage for prim...
journal_title:Indian journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2004-09-01 00:00:00
abstract::Modern vitreoretinal surgery is now one of the most effective tools for treating posterior segment diseases. Recent advances in the pathogenesis and classification and better indicators of visual outcome for idiopathic macular holes have led to a renewed interest in this clinical entity. Refinements in the techniques ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1998-12-01 00:00:00
abstract:PURPOSE:To compare Humphrey Visual Field Analyzer (HVF) and Frequency Doubling Perimetry (FDP) testing in the diagnosis of early glaucoma. METHODS:We performed HVF (24-2 standard full threshold) and FDP (N-30) evaluations in 34 consecutive patients with early primary glaucoma and 96 normal subjects. Early glaucoma was...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_488_17
更新日期:2018-01-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.4103/0301-4738.44512
更新日期:2009-01-01 00:00:00
abstract::Thirty-five coagulase negative Staphylococcus (CoNS) cultured from corneal ulcer were speciated and antibiotic sensitivity tested. S epidermidis was the commonest isolate and it was sensitive to ampicillin and vancomycin. ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.15288
更新日期:2005-03-01 00:00:00
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doi:10.4103/0301-4738.133485
更新日期:2014-05-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.62652
更新日期:2010-05-01 00:00:00
abstract::To report an unusual presentation of Fuch's endothelial dystrophy (FED) and its management. A 53-year-old male patient presented with unilateral progressive painless diminution of vision. Best-corrected visual acuity of the right and left eyes were 20/20 and 20/400, respectively. Slit lamp examination of the right eye...
journal_title:Indian journal of ophthalmology
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更新日期:2020-10-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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更新日期:2019-01-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.120206
更新日期:2014-03-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.4103/ijo.IJO_469_19
更新日期:2019-06-01 00:00:00
abstract::Ocular filariasis commonly presents as subconjunctival or eyelid nodules. We report a rare case of a live, motile worm causing floaters. The worm was isolated from the vitreous cavity and revealed to be Dirofilaria repens. Correct recognition of the worm is necessary as human dirofilariasis does not present as microfi...
journal_title:Indian journal of ophthalmology
pub_type:
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更新日期:2019-09-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
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更新日期:2017-09-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.119437
更新日期:2013-09-01 00:00:00
abstract::A rare case of unilateral cryptophthalmos have unique findings is reported. The lateral part of the left eye was replaced by downward extension of the frontal hairline. The left upper eyelid, except in the lateral 4mm fully developed portion, was replaced by a fold adherent to the underlying disorganized globe (6.9 mm...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00