Abstract:
Purpose:To analyze and report outcomes of microincision vitrectomy surgery (MIVS) for Stage 4 and 5 retinopathy of prematurity (ROP). Methods:Medical records of 202 eyes of 129 premature children undergoing MIVS for Stage 4/Stage 5 ROP between January 2012 and April 2015 were evaluated. The primary outcome measure was the proportion of eyes with anatomical success (defined as attached retina at the posterior pole at last follow-up). Complications associated with MIVS were noted and analysis of risk factors associated with poor anatomical outcome was also done using logistic regression. Results:Mean age of presentation of babies with Stage 4 ROP (2.9 ± 1.75 months) was lower than those with stage 5 disease (5.62 ± 2.55 months) (P < 0.005). One hundred seventeen eyes (56% or 58%) had Stage 5, 38 (19%) had Stage 4a, and 47 (23%) Stage 4b. Ninety-four eyes (47%) had received prior treatment (laser and/or anti-vascular endothelial growth factors [VEGF]). Lens-sparing vitrectomy (LSV) was performed in 58 (29%) eyes while lensectomy with vitrectomy (LV) was performed in 144 (71%) eyes. At a mean follow-up of 32.5 weeks, 102 (50.5%) eyes achieved anatomical success, including 74% eyes in Stage 4a and 4b and 33% in Stage 5. Complications included intraoperative break formation (19%), postoperative vitreous hemorrhage (28%), raised intraocular pressure (12.7%), and cataract progression (2.4%). Factors significantly associated with favorable anatomical outcome were Stage 4 disease (vs. Stage 5) (odds ratio [OR] 5.8; confidence interval [CI] =2.6-13.8, P < 0.005), prior treatment (laser ± anti-VEGF) (OR 2.5; CI 1.4-4.7, P < 0.005) surgery with 25G MIVS (vs. 23G) (OR: 1.7; CI = 0.98-3.00, P = 0.05) and LSV (vs. LV) (OR 7; CI = 3.4-14.6, P < 0.005). Retinal break was significantly associated with poor anatomical outcome (OR 0.21; CI = 0.09-0.5, P < 0.005). Conclusion:MIVS along with wide angle viewing systems allow surgeons to effectively manage ROP surgeries while at the same time reducing complication rate in these eyes which have complex pathoanatomy and otherwise grim prognosis.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Sen P,Bhende P,Sharma T,Gopal L,Maitray A,Shah P,Oke Ydoi
10.4103/ijo.IJO_1030_17subject
Has Abstractpub_date
2019-06-01 00:00:00pages
889-895issue
6eissn
0301-4738issn
1998-3689pii
IndianJOphthalmol_2019_67_6_889_259011journal_volume
67pub_type
杂志文章abstract::30 patients with epiphora and related complaints were investigated by Radionuclide Dacrocystography. It was possible to do this procedure easily in all age groups. The site of block in the lacrimal system could be accurately determined by this non-invasive technique. ...
journal_title:Indian journal of ophthalmology
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doi:
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
pub_type: 评论,信件
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abstract:BACKGROUND:Stimuli-sensitive hydrogels are three-dimensional, hydrophilic, polymeric networks capable of imbibing large amounts of water or biological fluids on stimulation, such as pH, temperature and ionic change. AIM:To develop hydrogels that are sensitive to stimuli, i.e. pH, in the cul-de-sac of the eye for provi...
journal_title:Indian journal of ophthalmology
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doi:10.4103/0301-4738.71677
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abstract:: ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_773_18
更新日期:2019-02-01 00:00:00
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journal_title:Indian journal of ophthalmology
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doi:10.4103/ijo.IJO_143_19
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.25834
更新日期:2006-06-01 00:00:00
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journal_title:Indian journal of ophthalmology
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doi:10.4103/0301-4738.42428
更新日期:2008-09-01 00:00:00
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journal_title:Indian journal of ophthalmology
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更新日期:2018-02-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.30704
更新日期:2007-03-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_465_20
更新日期:2020-12-01 00:00:00
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journal_title:Indian journal of ophthalmology
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更新日期:2020-01-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 评论,信件
doi:10.4103/ijo.IJO_1633_18
更新日期:2019-02-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1997-03-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_1492_19
更新日期:2020-06-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.4103/0301-4738.195590
更新日期:2016-11-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.21614
更新日期:2006-03-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.182939
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.136227
更新日期:2014-06-01 00:00:00
abstract::Pupillary block glaucoma is a common complication of cataract surgery, especially following anterior chamber intraocular lens implantation. We report a case of pupillary block glaucoma with a posterior chamber IOL that was implanted in the anterior chamber following a complicated extracapsular cataract extraction. The...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVE:Evaluation of the clinical profile and distribution of different sub-types of amblyopia in a referral eye hospital in India. METHODS:This was a prospective hospital-based observational study, evaluating the clinical profile of patients with amblyopia presenting to a referral strabismology practice. The exami...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.18903
更新日期:2005-12-01 00:00:00
abstract:: ...
journal_title:Indian journal of ophthalmology
pub_type: 评论,信件
doi:10.4103/ijo.IJO_723_18
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.64136
更新日期:2010-07-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_352_17
更新日期:2017-12-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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