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Gastrin releasing peptide (GRP) receptor targeted radiopharmaceuticals: a concise update.

Abstract：

:The gastrin releasing peptide (GRP) receptor is becoming an increasingly attractive target for development of new radiolabeled peptides with diagnostic and therapeutic potential. The attractiveness of the GRP receptor as a target is based upon the functional expression of GRP receptors in several tumors of neuroendocrine origin including prostate, breast, and small cell lung cancer. This concise review outlines some of the efforts currently underway to develop new GRP receptor specific radiopharmaceuticals by employing a variety of radiometal chelation systems.

journal_name

Nucl Med Biol

journal_title

Nuclear medicine and biology

authors

Smith CJ,Volkert WA,Hoffman TJ

doi

10.1016/s0969-8051(03)00116-1

keywords:

subject

Has Abstract

pub_date

2003-11-01 00:00:00

pages

861-8

issue

8

eissn

0969-8051

issn

1872-9614

pii

S0969805103001161

journal_volume

30

pub_type

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