当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF PHARMACEUTICS期刊下所有文献 > Dual-stimuli-responsive hydrogels based on poly(N-isopropylacrylamide)/chitosan semi-interpenetrating networks.

Dual-stimuli-responsive hydrogels based on poly(N-isopropylacrylamide)/chitosan semi-interpenetrating networks.

Abstract：

:The synthesis and characterisation of semi-interpenetrating polymeric networks obtained by the radical-induced polymerisation of N-isopropylacrylamide in the presence of chitosan using tetraethyleneglycoldiacrylate as the crosslinker is described. The influence of the degree of crosslinking and that of the ratio of chitosan to poly(N-isopropylacrylamide) on the "pH/temperature induced" phase transition behaviour and swelling characteristics of the hydrogel system are investigated. The ability of the same system to act as a controlled release vehicle for pilocarpine hydrochloride is evaluated.

journal_name

Int J Pharm

journal_title

International journal of pharmaceutics

authors

Verestiuc L,Ivanov C,Barbu E,Tsibouklis J

doi

10.1016/j.ijpharm.2003.09.031

keywords:

subject

Has Abstract

pub_date

2004-01-09 00:00:00

pages

185-94

issue

1

eissn

0378-5173

issn

1873-3476

pii

S0378517303005349

journal_volume

269

pub_type

杂志文章

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