Effects of acetylcholine antagonist injection into the prefrontal cortex on the progress of lever-press extinction in rats.

abstract：:Recent reports have suggested that variants in the sortilin-related receptor gene (SORL1) increase the risk of late onset Alzheimer's disease (AD) in Northern European, Hispanic, African-American and Isreali-Arab populations. SORL1 directs trafficking of amyloid precursor protein (APP) and under-expression of SORL1 ma...

journal_title：Neuroscience letters

authors： Lee JH,Chulikavit M,Pang D,Zigman WB,Silverman W,Schupf N

更新日期：2007-09-25 00:00:00

abstract：:Previously published data have indicated that in the rat, unlike other species examined, the kidney is not supplied by sensory nerves containing substance P (SP). As part of a study of reflex control of renal function in the rat, we have now reassessed this situation. Many fine, varicose, SP-immunoreactive nerve fiber...

journal_title：Neuroscience letters

authors： Ferguson M,Bell C

更新日期：1985-09-30 00:00:00

abstract：:Corticotropin-releasing factor (CRF) is present in climbing fibers and their terminations on Purkinje neurons. To determine whether CRF may have a postsynaptic action in this pathway, CRF effects on the electrophysiological properties of cultured cerebellar Purkinje neurons were studied. CRF produced a dose-dependent ...

journal_title：Neuroscience letters

authors： Fox EA,Gruol DL

更新日期：1993-01-04 00:00:00

abstract：:The effect of various ionic solutions microinjected into the nucleus tractus solitarii (NTS) on blood pressure, heart rate and respiration rate was investigated in urethane-anesthetized rats. Unilateral microinjection of solutions containing NaCl (154 mM), NaCl (154 mM) and KCl (2.8 mM) or NaNO3 (154 mM) into a restri...

journal_title：Neuroscience letters

authors： Lukovic L,de Jong W

更新日期：1990-03-02 00:00:00

abstract：:The contribution of retinal and extraretinal signals to the coding of eye position in the head was studied in human subjects (Ss). Horizontal saccades were produced in darkness. For some trials, before returning gaze direction to the starting position, a visual signal briefly stimulated the foveal retina. Results show...

journal_title：Neuroscience letters

authors： Blouin J,Gauthier GM,Vercher JL

更新日期：1995-01-09 00:00:00

abstract：:Converging evidence demonstrates an important role for gangliosides in brain function and neurodegenerative diseases. Exogenous GM1 is broadly neuroprotective, including in rodent, feline, and primate models of Parkinson's disease, and has shown positive effects in clinical trials. We and others have shown that inhibi...

journal_title：Neuroscience letters

authors： Dhanushkodi A,Xue Y,Roguski EE,Ding Y,Matta SG,Heck D,Fan GH,McDonald MP

更新日期：2019-01-23 00:00:00

abstract：:We raised polyclonal antibodies against the C-terminal peptides of protein kinase C (PkC) subspecies alpha, beta 1, beta 2, gamma, delta, epsilon, and zeta and checked their specificity against brain extracts using Western immunoblot analysis. With equal amounts of protein applied to gels PkC subspecies beta 1, delta,...

journal_title：Neuroscience letters

authors： Gott AL,Mallon BS,Paton A,Groome N,Rumsby MG

更新日期：1994-04-25 00:00:00

abstract：:In chick brain microvessels, monoamine oxidase activity using catecholamines (dopamine and noradrenaline) and indoleamines (serotonin and tryptamine) as substrates was higher than that measured in synaptosomes and free mitochondria. In contrast, phenylalkyamines such as tyramine and 2-phenylethylamine were more deamin...

journal_title：Neuroscience letters

authors： Durand M

更新日期：1986-12-12 00:00:00

abstract：:Employing double anterograde axonal tracing in combination with intracortical microstimulation, we examined the distribution patterns of corticosubthalamic inputs from forelimb representations of the dorsal (PMd) and ventral (PMv) divisions of the premotor cortex in the macaque monkey. The inputs from the PMd and PMv ...

journal_title：Neuroscience letters

authors： Nambu A,Tokuno H,Inase M,Takada M

更新日期：1997-12-12 00:00:00

abstract：:Pulsed magnetic fields (patent pending) consisting of approximately 100 microT (peak), frequency modulated, extremely low frequency magnetic fields (ELFMF) were shown to induce a significant degree of antinociception ('analgesia') in the land snail Cepaea nemoralis. Fifteen minute exposures to a specific magnetic fiel...

journal_title：Neuroscience letters

authors： Thomas AW,Kavaliers M,Prato FS,Ossenkopp KP

更新日期：1997-01-31 00:00:00

abstract：:To differentiate the opiate (naloxone) receptor and the enkephalin receptor in rat brain, we solubilized the receptor molecules by detergent and determined the molecular weights by gel filtration. The receptor preparation was bound to [3H] naloxone or [3H] Met5-enkephalin, and was solubilized by Triton X-100. On gel c...

journal_title：Neuroscience letters

authors： Ogawa N,Yamawaki Y,Kuroda H,Nukina I,Ofuji T

更新日期：1981-12-11 00:00:00

abstract：:ATP is an important extracellular messenger in the CNS. In the hippocampus, a brain structure relevant for learning and memory processes, it acts both as a modulator and as a mediator of synaptic transmission, with implications for synaptic plasticity phenomena. Recent evidence suggests that ATP modulates activity-dep...

journal_title：Neuroscience letters

authors： da Silva BM,de Mendonça A,Ribeiro JA

更新日期：2005-08-05 00:00:00

abstract：:We evaluated the neuroprotective effects of systemically administered magnesium against N-methyl-D-aspartate (NMDA)-mediated brain injury in perinatal rats. Postnatal day (PND) 7 rats received unilateral intrastriatal injections of 25 nmol NMDA followed 15 min later by single or multiple doses of magnesium intraperito...

journal_title：Neuroscience letters

authors： McDonald JW,Silverstein FS,Johnston MV

更新日期：1990-02-05 00:00:00

abstract：:The aim of this study was to clarify whether 12-lipoxygenase (12-LOX) activation was involved in reactive oxygen species (ROS) generation, extensive poly(ADP-ribose) polymerase (PARP) activation and neuronal death induced by glucose-deprivation, followed by glucose-reload (GD/R). The decrease of neuronal viability and...

journal_title：Neuroscience letters

authors： Nagasawa K,Kakuda T,Higashi Y,Fujimoto S

更新日期：2007-12-18 00:00:00

abstract：:The fundamental pathological process(es) associated with schizophrenia (SZ) remain(s) uncertain, but multiple lines of evidence suggest that this condition is associated with excessive stimulation of striatal dopamine (DA) D2 receptors, deficient stimulation of medial prefrontal cortex (mPFC) D1 receptors as well as n...

journal_title：Neuroscience letters

authors： Zhang L,Zhou R,Xiang G

更新日期：2005-08-05 00:00:00

abstract：:The melanocortin receptor type 2 (MC2R or adrenocorticotropic hormone, ACTH receptor) gene (MC2R) encodes a protein involved in regulation of adrenal cortisol secretion, important in the physiological response to stressors. A variant of MC2R, -179A>G, results in reduction of promoter activity and less adrenal action. ...

journal_title：Neuroscience letters

authors： Proudnikov D,Hamon S,Ott J,Kreek MJ

更新日期：2008-04-25 00:00:00

abstract：:The Dex/CRH test is one of the most reliable neuroendocrine function tests for hypothalamic-pituitary-adrenocortical (HPA) system dysregulation in depression. Persistent overdrive of HPA system activity after successful antidepressant treatment predicts an enhanced risk for relapse of a depressive episode. As the reni...

journal_title：Neuroscience letters

authors： Baghai TC,Schule C,Zwanzger P,Minov C,Zill P,Ella R,Eser D,Oezer S,Bondy B,Rupprecht R

更新日期：2002-08-16 00:00:00

abstract：:The pathogenic mechanism underlying Parkinson's disease (PD) and PD- Cognitive impairment (CI) remains elusive. Its potential link to the risk factors in Alzheimer's disease (AD) is unclear. In this study, we analyzed 16 CE-associated single nucleotide polymorphisms (SNPs) in twelve genes in a Chinese cohort of 450 PD...

journal_title：Neuroscience letters

authors： Fang L,Tang BS,Fan K,Wan CM,Yan XX,Guo JF

更新日期：2018-06-11 00:00:00

abstract：:Functional recovery after experimental stroke in rats is enhanced by environmental enrichment by stimulating plastic changes in brain regions outside the lesion, but the molecular mechanisms are not known. We investigated the effect of environmental enrichment after focal cerebral ischemia on cognitive recovery and hi...

journal_title：Neuroscience letters

authors： Rönnbäck A,Dahlqvist P,Svensson PA,Jernås M,Carlsson B,Carlsson LM,Olsson T

更新日期：2005-09-09 00:00:00

abstract：:We studied event-related desynchronization (ERD) of the 8-13 Hz rhythm (mu rhythm) of the primary somatosensory cortex (SI) caused by contra- and ipsilateral median-nerve stimulation. We used whole-head magnetoencephalography (MEG) and wavelet analysis together with our newly developed color-coded single-trial ERD dis...

journal_title：Neuroscience letters

authors： Nikouline VV,Linkenkaer-Hansen K,Wikström H,Kesäniemi M,Antonova EV,Ilmoniemi RJ,Huttunen J

更新日期：2000-11-24 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) is a very important mitogenic factor with proved neurogenesis effects in the central nervous system. Intranasal administration can bypass blood-brain barrier and deliver drugs into the brain directly. We investigated whether intranasal administration of bFGF at later time points a...

journal_title：Neuroscience letters

authors： Wang ZL,Cheng SM,Ma MM,Ma YP,Yang JP,Xu GL,Liu XF

更新日期：2008-11-28 00:00:00

abstract：:Cellular origins of methylarginines are not precisely known but the presence of free methyl and dimethylarginines in the brain were reported. We have investigated the circulating concentrations of asymmetrical dimethylarginine NG,NG-dimethylarginine (ADMA), NG,NG-dimethylarginine (SDMA), nitrate and nitrite levels in ...

journal_title：Neuroscience letters

authors： Das I,Khan NS,Puri BK,Hirsch SR

更新日期：1996-09-13 00:00:00

abstract：:It is known that mice homozygous for the retinal degeneration (rd) mutation are able to synchronize their circadian rhythms to light-dark cycles. In the present experiments mice were given a choice of a dark or an illuminated living and nesting area. C3H, CBA and C57 rd/rd mice spent more time in the dark than in the ...

journal_title：Neuroscience letters

authors： Mrosovsky N,Hampton RR

更新日期：1997-02-07 00:00:00

abstract：:The endogenously synthesized nonapeptide arginine vasopressin (AVP) is thought to be involved in transduction of photic information to the pineal gland. The enhancement of circulating AVP leads to a suppression of the nocturnal melatonin surge the mechanisms of which are unknown so far. We therefore studied the effect...

journal_title：Neuroscience letters

authors： Stehle J,Reuss S,Riemann R,Seidel A,Vollrath L

更新日期：1991-02-11 00:00:00

abstract：:It is believed that subjects with high trait anxiety levels tend to present state anxiety reactions with greater intensity than individuals with low trait anxiety levels. In order to verify if this premise is valid for animal models of anxiety, the present work investigated the possible correlation between two behavio...

journal_title：Neuroscience letters

authors： Goes TC,Antunes FD,Teixeira-Silva F

更新日期：2009-02-06 00:00:00

abstract：:During neuronal development, the neuroepithelial stem cells (NSCs) initially undergo proliferative divisions, later switching to neurogenic ones whereby one NSC and a post-mitotic neuron are generated. We recently showed that a member of the PRDM family of transcriptional regulators, PRDM4/SC1, recruits a type II prot...

journal_title：Neuroscience letters

authors： Chittka A

更新日期：2013-08-29 00:00:00

abstract：:The distribution of Purkinje cells projecting to the descending vestibular nucleus was studied in lobule IX (uvula) of the cat by the retrograde wheat germ agglutinin-horseradish peroxidase method. In the transverse plane labeled Purkinje cells were seen diffusely within 1.0 mm from the midline and densely for 250-500...

journal_title：Neuroscience letters

authors： Matsushita M,Wang CL

更新日期：1986-05-23 00:00:00

abstract：:We examined the suggestion that some of the processes subserving learning through action-observation and motor-execution are different because sensory motor reafference is not available while the limb is at rest in the former condition. We confirmed the action-observation and motor-execution groups learned equally the...

journal_title：Neuroscience letters

authors： Hayes SJ,Andrew M,Elliott D,Roberts JW,Bennett SJ

更新日期：2012-01-11 00:00:00

abstract：:Survivors of bacterial meningitis frequently suffer from long-term sequelae, particularly from learning and memory deficits. For this reason, spatial memory and learning was studied in a mouse model of ceftriaxone-treated Streptococcus pneumoniae meningitis. Persistent deficits of spatial learning despite normal motor...

journal_title：Neuroscience letters

authors： Wellmer A,Noeske C,Gerber J,Munzel U,Nau R

更新日期：2000-12-22 00:00:00

abstract：:English /l/ and /r/ sounds are not distinctive for Japanese speakers and they are loosely associated with corresponding graphemes. The purpose of this study was to investigate the brain activities in the memory process for the graphemes containing 'l' and 'r' in Japanese speakers. Two functional magnetic resonance ima...

journal_title：Neuroscience letters

authors： Sumiyoshi C,Matsuo K,Kato C,Ozawa F,Takehara Y,Isoda H,Isogai S,Sakahara H,Nakai T

更新日期：2003-01-09 00:00:00