Abstract:
:The Smith-Etherington extrathoracic (ET) clearance model has been developed to describe clearance from the human nasal passage as observed for 1.5, 3 and 6 microm monodisperse particles inhaled by participants while sitting or at light exercise. Model parameter values have been determined for 22 sets of nasal clearance data from which typical nasal clearance parameter values have been derived. In this investigation, the faecal excretion of 5 microm activity median aerodynamic diameter (AMAD) Type S 239Pu was calculated for three sets of model parameter values, i.e. typical values and those determined for two experiments that respectively exhibited particularly rapid and slow clearance. The study has shown that a greater fraction of material deposited in ET is cleared to the GI tract, and that this clearance takes place over a longer period than assumed by the Human Respiratory Tract Model for Radiological Protection. The study has also shown that deliberate nose blow sampling might potentially be developed to determine the order of magnitude of intakes.
journal_name
Radiat Prot Dosimetryjournal_title
Radiation protection dosimetryauthors
Smith JRdoi
10.1093/oxfordjournals.rpd.a006205keywords:
subject
Has Abstractpub_date
2003-01-01 00:00:00pages
119-22issue
1-4eissn
0144-8420issn
1742-3406journal_volume
105pub_type
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
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