Abstract:
:The acute toxicity of fatty acids (C14 to C18) commonly found in wood was determined by the standard algal growth inhibition test using the freshwater green alga Selenastrum capricornutum. Toxicity, quantified as IC50 values, varied depending on the number of total carbons and double bonds. Of the tested acids, oleic (cis-9-octadecenoic) acid showed the highest toxicity (72-h IC50 = 0.47 mg/L) to the alga, and triolein, a triglyceride of oleic acid, showed no apparent toxicity. Further examination of a series of C18:1 acids with a double bond at the 6, 11, or 12 position revealed that both double-bond position and cis or trans configuration affected toxicity. The 72-h IC50 data for these fatty acids and related compounds seemed to correlate well with the melting point (mp), showing two separate linear relationships: at mp < 35 degrees C toxicity increased with increasing melting point, and at mp > 40 degrees C toxicity decreased with melting point.
journal_name
Environ Toxicoljournal_title
Environmental toxicologyauthors
Kamaya Y,Kurogi Y,Suzuki Kdoi
10.1002/tox.10127keywords:
subject
Has Abstractpub_date
2003-10-01 00:00:00pages
289-94issue
5eissn
1520-4081issn
1522-7278journal_volume
18pub_type
杂志文章abstract::Indium, a rare earth metal characterized by high plasticity, corrosion resistance, and a low melting point, is widely used in the electronics industry, but has been reported to be an environmental pollutant and a health hazard. We designed a study to investigate the effects of subacute exposure of indium compounds on ...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.22022
更新日期:2016-01-01 00:00:00
abstract::Acute toxicities of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) were tested on four freshwater species and three plant species. PFOS was more toxic than PFOA for all species tested in this study. Similar time-response patterns of PFOS and PFOA toxicity were observed for each tested species. Valu...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.20396
更新日期:2009-02-01 00:00:00
abstract::Fascinating super paramagnetic uniqueness of iron oxide particles at nano-scale level make them extremely useful in the state of the art therapies, equipments, and techniques. Cobalt ferrite (CoFe2 O4 ) magnetic nanoparticles (MNPs) are extensively used in nano-based medicine and electronics, results in extensive disc...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.22206
更新日期:2016-12-01 00:00:00
abstract::There is increasing worldwide interest in developing of markers for tumor diagnosis and identification of individuals who are at high cancer risk. Cancer, like other diseases accompanied by metabolic disorders, causes characteristic effects on cell turnover rate, activity of modifying enzymes, and RNA/DNA modification...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.21970
更新日期:2015-07-08 00:00:00
abstract::Butein is a flavonoid isolated from various medicinal plants. It is known to have different biological activities including anti-inflammation, anti-adipogenesis, and anti-angiogenesis. In the study, we demonstrated the anti-proliferative effect of butein in human osteosarcoma U-2 OS cells. Our data showed that butein ...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.23079
更新日期:2020-12-16 00:00:00
abstract::Inflammation generated by environmental toxicants including pesticides could be one of the factors underlying neuronal cell damage in neurodegenerative diseases. In this study, we investigated the mechanisms by which inflammatory responses contribute to apoptosis in PC12 cells treated with diquat. We found that diquat...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.22552
更新日期:2018-10-01 00:00:00
abstract::So far, little is known on the distribution of hepatotoxic microcystin (MC) in various organs of bivalves, and there is no study on MC accumulation in bivalves from Chinese waters. Distribution pattern and seasonal dynamics of MC-LR, -YR and -RR in various organs (hepatopancreas, intestine, visceral mass, gill, foot, ...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.20146
更新日期:2005-12-01 00:00:00
abstract::Di(2-ethylhexyl) phthalate, which is a ubiquitous environmental contaminant because of its extensive use as a plasticizer, is a potential nongenotoxic carcinogen. To assess the effects of DEHP exposure on the cytoskeleton of Chironomus, we characterized full-length cDNA sequences of the calponin gene from Chironomus r...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.20463
更新日期:2009-12-01 00:00:00
abstract::Avian vacuolar myelinopathy (AVM) is a neurological disease affecting bald eagles (Haliaeetus leucocephalus), American coots (Fulica americana), waterfowl, and other birds in the southeastern United States. The cause of the disease is unknown, but is thought to be a naturally produced toxin. AVM is associated with aqu...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.20424
更新日期:2009-08-01 00:00:00
abstract::Airborne particulates, especially fine particles and bound chemical compounds, are a potential mediator of adverse health effects. In this study an analysis was done of the concentration and size distribution of air particulate matter, the content of bound polycyclic aromatic hydrocarbons (PAHs), and the biological ef...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.10054
更新日期:2002-01-01 00:00:00
abstract::Domestic exposure to biomass smoke represents the second cause of chronic obstructive lung disease. Previous studies have shown that exposure of guinea pigs to wood smoke is capable of generating oxidative stress in lung tissue, and this may involve a failure at a mitochondrial level, given its close relation with the...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.21922
更新日期:2015-04-01 00:00:00
abstract::Oral submucous fibrosis (OSF) has been indicated as one of the oral potentially malignant disorders. Epidemiological studies have attributed this pathological fibrosis to the habit of areca nuts chewing, which causes chronic inflammation and persistent activation of myofibroblasts in the oral cavity. Hence, it is cruc...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.22489
更新日期:2018-01-01 00:00:00
abstract::The toxicity and chemical quality of surface water and sediment in the River Traun in Austria were studied because of recurrent fish mortality in some alpine rivers over the last few years. The analyses were carried out on samples collected during winter and summer upstream and downstream of two municipal wastewater t...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.20027
更新日期:2004-08-01 00:00:00
abstract::The chronic effect of p-nonylphenol on survival and reproduction for two generations of the freshwater cladoceran Daphnia galeata was examined by life table experiments. The effects on survival and reproduction were used as the intrinsic rate of natural increase, r, with the Euler-Lotka equation and were analyzed with...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.10083
更新日期:2002-10-01 00:00:00
abstract::In the present study, the modulatory effect of phytol against benzo(a)pyrene [B(a)P] induced lung carcinogenesis was investigated in Swiss albino mice. During the experimental period, phytol treatment showed no adverse toxic effect and mortality to the experimental animals. Lung tumor was observed in B(a)P treated gro...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.22690
更新日期:2019-04-01 00:00:00
abstract::Recent epidemiological studies have revealed significant positive associations between exposure to organochlorine (OC) pesticides and occurrence of the metabolic syndrome and there are a growing number of animal-based studies to support causality. However, the cellular mechanisms linking OC compound exposure and metab...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.22583
更新日期:2018-09-01 00:00:00
abstract::Hydroponics studies were conducted to investigate the antioxidant adaptations, ascorbate and glutathione metabolism in hyperaccumulating ecotype of Sedum alfredii (HE) exposed to high Cd environment, when compared with its nonhyperaccumulating ecotype (NHE). Exposure to Cd induced a burst of oxidative stress in both e...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.20362
更新日期:2008-08-01 00:00:00
abstract::Fluorescent pseudomonads were a major component [log (10) 4.2-6.1 colony-forming units mL-1] of the culturable heterotrophic gram-negative bacterioplankton observed in three Mississippi Delta oxbow lakes in this study. Pure cultures of fluorescent pseudomonads were isolated from three Mississippi Delta oxbow lakes (18...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/1522-7278(2001)16:1<9::aid-tox20>3.0.co;2-
更新日期:2001-01-01 00:00:00
abstract::Chronic lead exposure causes peripheral sympathetic nerve stimulation, including increased blood pressure and heart rate. Purinergic receptors are involved in the sympathoexcitatory response induced by myocardial ischemia injury. However, whether P2X4 receptor participates in sympathoexcitatory response induced by chr...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.22547
更新日期:2018-06-01 00:00:00
abstract::Hypothyroxinemia induced by maternal mild iodine deficiency causes neurological deficits and impairments of brain function in offspring. Hypothyroxinemia is prevalent in developing and developed countries alike. However, the mechanism underlying these deficits remains less well known. Given that the myelin plays an im...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.21997
更新日期:2015-11-01 00:00:00
abstract::Seasonal changes in developmental stages, condition factor (CF), gonadosomatic index, and plasma vitellogenin (Vtg) concentrations in male and female hornyhead turbot were examined at the wastewater outfall (T1) of the Orange County Sanitation District, and two farfield sites T11 (7.7 km northwest of the outfall) and ...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.20287
更新日期:2007-10-01 00:00:00
abstract::Ecological risk assessments are, in part, based on results of toxicity tests conducted under standard exposure conditions. Global climate change will have a wide range of effects on estuarine habitats, including potentially increasing water temperature and salinity, which may alter the risk assessment of estuarine pol...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.20726
更新日期:2013-07-01 00:00:00
abstract::Tributyltin (TBT), a proven endocrine-disrupting chemical, is well known to induce imposex in female gastropods. Herein we demonstrate the effects of low doses of tributyltin chloride (TBTCl) on the female offspring of KM mice. Pregnant mice were administered by gavage with 0, 1, 10, or 100 μg TBTCl/kg body weight/day...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.21756
更新日期:2012-11-01 00:00:00
abstract::Acetaminophen (APAP) is one of the few recommended analgesic and antipyretic drugs in some critical cases such as viral disease COVID-19. However, the unrestricted use of APAP develops liver disorders. Hepatotoxicity and liver injury can also be induced by ionizing radiation (IR) during radiotherapy. The data of the c...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.23077
更新日期:2020-12-17 00:00:00
abstract::Effects of perchlorate on sodium-iodide symporter (NIS) and pendrin gene expression in deer mice kidney and stomach were investigated. This was accomplished by isolating a partial cDNA sequence of deer mice NIS gene of 425 bps, and quantitatively analyzing NIS mRNA expression in various deer mouse tissues. The highest...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.20271
更新日期:2007-08-01 00:00:00
abstract::An enormous quantity of pharmacologically active principles are currently being introduced into the environment, with consequent escalation of environmental problems, but only a small number of studies are focusing on an assessment of their genotoxic effects. The aim of this article is to assess the genotoxic effects ...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.20685
更新日期:2012-10-01 00:00:00
abstract::Rheumatoid arthritis (RA) is the most common type of chronic inflammatory disease which is triggered by dysfunction in the immune system which in turn affects synovial joints. Current treatment of RA with NSAIDs and DMRDs is limited by their side effect. As a result, the interest in alternative, well tolerated anti-in...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.22264
更新日期:2017-02-01 00:00:00
abstract::Safrole is one of important food-borne phytotoxin that exhibits in many natural products such as oil of sassafras and spices such as anise, basil, nutmeg, and pepper. This study was performed to elucidate safrole-induced apoptosis in human tongue squamous carcinoma SCC-4 cells. The effect of safrole on apoptosis was m...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.20658
更新日期:2012-07-01 00:00:00
abstract::Several estuaries along the Pacific Ocean coast of North America were identified recently as having elevated 4-nonylphenol (4-NP) in sediments and biota, raising concerns about reproductive impacts for wildlife given 4-NP's established estrogenic activity as an endocrine-disrupting compound. Here we characterize 4-NP ...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.22371
更新日期:2017-05-01 00:00:00
abstract::The aim of this study was to examine the occurrence of endocrine disruption close to sewage treatment plant effluent discharges along the Finnish Baltic Sea coast using a set of reproductive biomarkers present in adult three-spined stickleback (Gasterosteus aculeatus). Possible variation and sensitivity of the biomark...
journal_title:Environmental toxicology
pub_type: 杂志文章
doi:10.1002/tox.20715
更新日期:2013-04-01 00:00:00