An extract of Hydrilla verticillata and associated epiphytes induces avian vacuolar myelinopathy in laboratory mallards.

abstract：:Colorectal cancer (CC) is an important human malignancy with high cancer related death worldwide. The chemotherapy using doxorubicin hydrochloride is one of the most common cancer therapeutic methods. However, drug resistance lowers the treatment efficacy in CC patients. The combination therapies seem to be more promi...

journal_title：Environmental toxicology

authors： Jadid MFS,Aghaei E,Taheri E,Seyyedsani N,Chavoshi R,Abbasi S,Khorrami A,Goleij P,Hajazimian S,Taefehshokr S,Isazadeh A,Shanehbandi D

更新日期：2021-01-28 00:00:00

abstract：:Hypothyroxinemia induced by maternal mild iodine deficiency causes neurological deficits and impairments of brain function in offspring. Hypothyroxinemia is prevalent in developing and developed countries alike. However, the mechanism underlying these deficits remains less well known. Given that the myelin plays an im...

journal_title：Environmental toxicology

authors： Wei W,Wang Y,Dong J,Wang Y,Min H,Song B,Shan Z,Teng W,Xi Q,Chen J

更新日期：2015-11-01 00:00:00

abstract：:Although marine and coastal environments which are contaminated with xenobiotic organic compounds often become hypoxic during the summer, the interactive effects of hypoxia and xenobiotic exposure on marine species such as teleost fishes remain poorly understood. The expression and activity of monooxygenase enzyme cyt...

journal_title：Environmental toxicology

authors： Rahman MS,Thomas P

更新日期：2018-04-01 00:00:00

abstract：:di-N-butylphthalate (DBP) is a ubiquitous environmental pollutant used for plastic coating and in the cosmetics industry. It has toxic effects on body health, especially the male reproductive system. Here, we investigated the effects of DBP on the male reproductive system of pubertal mice and explored the protective r...

journal_title：Environmental toxicology

authors： Jiang XP,Tang JY,Xu Z,Han P,Qin ZQ,Yang CD,Wang SQ,Tang M,Wang W,Qin C,Xu Y,Shen BX,Zhou WM,Zhang W

更新日期：2017-07-01 00:00:00

abstract：:As a widely used plasticizer in industry, di-2-ethylhexylphthalate (DEHP) can cause testicular toxicity, yet little is known about the potential mechanism. In this study, DEHP exposure dramatically inhibited cellviability and induced apoptosis of mouse GC-1 spg cells. Furthermore, DEHP significantly increased the leve...

journal_title：Environmental toxicology

authors： Gan Y,Yang D,Yang S,Wang J,Wei J,Chen J

更新日期：2020-02-01 00:00:00

abstract：:Methoxychlor (MXC), an organochloride insecticide, is a potent toxicant-targeting female reproductive system and known to cause follicular atresia by inducing apoptosis within granulosa cells. Oxidative stress plays a pivotal role in apoptosis; thus, this study focuses on the ameliorative action of N-acetyl cysteine (...

journal_title：Environmental toxicology

authors： Bhardwaj JK,Saraf P

更新日期：2017-01-01 00:00:00

abstract：:Indium, a rare earth metal characterized by high plasticity, corrosion resistance, and a low melting point, is widely used in the electronics industry, but has been reported to be an environmental pollutant and a health hazard. We designed a study to investigate the effects of subacute exposure of indium compounds on ...

journal_title：Environmental toxicology

authors： Lee KH,Chen HL,Leung CM,Chen HP,Hsu PC

更新日期：2016-01-01 00:00:00

abstract：:Perfluorooctane sulfonate (PFOS) is an animal carcinogen. However, the underlying mechanism in cancer initiation is still largely unknown. Recently identified microRNAs (miRNAs) may play an important role in toxicant exposure and in the process of toxicant-induced tumorigenesis. We used PFOS to investigate PFOS-induce...

journal_title：Environmental toxicology

authors： Wang F,Liu W,Jin Y,Wang F,Ma J

更新日期：2015-05-01 00:00:00

abstract：:Particulate matter the environmental toxicant, with a diameter less than or equal to 2.5 μm (PM2.5 ) is a common cause of several respiratory diseases. In recent years, several studies have suggested that PM2.5 can influence diverse diseases, such as respiratory diseases, cardiovascular diseases, metabolic diseases, d...

journal_title：Environmental toxicology

authors： Kim W,Cho Y,Song MK,Lim JH,Kim JY,Gye MC,Ryu JC

更新日期：2018-11-01 00:00:00

abstract：:Manganese (Mn) plays a critical role in individual growth and development, yet excessive exposure can result in neurotoxicity, especially cognitive impairment. Neuronal apoptosis is considered as one of the mechanisms of Mn-induced neurotoxicity. Recent evidence suggests that cAMP-PKA-CREB signaling regulates apoptosi...

journal_title：Environmental toxicology

authors： Yang Y,Ma S,Wei F,Liang G,Yang X,Huang Y,Wang J,Zou Y

更新日期：2019-09-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used therapeutic agents; however, their pharmacological actions raise concerns about potential risks to the reproductive health of aquatic vertebrates. In the present study, a medaka ovulation assay was applied as an in vitro model to evaluate NSAID-induced anti...

journal_title：Environmental toxicology

authors： Yokota H,Eguchi S,Hasegawa S,Okada K,Yamamoto F,Sunagawa A,Tanaka M,Yamamoto R,Nakano E

更新日期：2016-12-01 00:00:00

abstract：:Toxins in cyanobacteria are a recognized risk in the treatment of drinking-water treatment. Cyanotoxins can occur in two modifications: cell bound and dissolved in water. The process of toxin release may occur naturally, but it also may be induced through the processes of drinking-water treatment. Both causes of relea...

journal_title：Environmental toxicology

authors： Schmidt W,Willmitzer H,Bornmann K,Pietsch J

更新日期：2002-01-01 00:00:00

abstract：:Patulin is a mold toxin secreted mainly by fungi of the Penicillium species. Exposure generally results from consumption of moldy fruits and fruit products. Since recent studies identified mold exposure as a risk factor for allergic diseases, we examined the effects of patulin on human peripheral blood mononuclear cel...

journal_title：Environmental toxicology

authors： Luft P,Oostingh GJ,Gruijthuijsen Y,Horejs-Hoeck J,Lehmann I,Duschl A

更新日期：2008-02-01 00:00:00

abstract：:Antioxidative enzymes (superoxide dismutase (SOD), peroxidase (POD), catalase (CAT), ascorbate peroxidase (APX)), as well as lipid peroxidation and proline were studied in moss Brachythecium piligerum Card. collected from different sites in Shanghai, China, to validate the physiological parameters as biomarkers of atm...

journal_title：Environmental toxicology

authors： Sun SQ,He M,Wang GX,Cao T

更新日期：2011-10-01 00:00:00

abstract：:We hypothesized that chronic exposure to arsenic would deplete the reduced glutathione (GSH) and methionine in vivo, thereby impair the methylation capacity of inorganic arsenic (iAs) ingested. Our experiment was designed to explore the effects of exogenous GSH and methionine on arsenic methylation in mice exposed to ...

journal_title：Environmental toxicology

authors： Jin Y,Zhao F,Zhong Y,Yu X,Sun D,Liao Y,Lv X,Li G,Sun G

更新日期：2010-08-01 00:00:00

abstract：:In the present study, responses of the Chinese brown frog (Rana chensinensis) to exposure to di-2-ethylhexyl phthalate (DEHP), a common plasticizer, during the larval period were characterized. The effects of DEHP on metamorphosis rate, thyroid hormone, thyroid histology and the expression of genes involved in the ste...

journal_title：Environmental toxicology

authors： Zhang Y,Li X,Gao J,Wang H

更新日期：2018-01-01 00:00:00

abstract：:Cyanotoxins are a group of compounds produced by cyanobacteria that can have severe physiological effects on other organisms, including humans. The potential allelopathic effects of Microcystis aeruginosa, a toxic cyanobacterium, on the duckweed plant, Lemna gibba L., were examined using three experimental methods: (1...

journal_title：Environmental toxicology

authors： LeBlanc S,Pick FR,Aranda-Rodriguez R

更新日期：2005-02-01 00:00:00

abstract：:Throughout life, the human eye is continuously exposed to sunlight and artificial lighting. Ambient light exposure can lead to visual impairment and transient or permanent blindness. To mimic benign light stress conditions, Mus musculus eyes were exposed to low-energy UVB radiation, ensuring no severe morphological ch...

journal_title：Environmental toxicology

authors： An MJ,Kim CH,Nam GY,Kim DH,Rhee S,Cho SJ,Kim JW

更新日期：2018-01-01 00:00:00

abstract：:Melamine is a heterocyclic, aromatic amine and nitrogen-enriched environmental toxicant, found in not only adulterated foodstuffs but also industrial household tableware and paints. Previous studies demonstrated adverse effects of high-dose melamine on human infants and pregnant animals, but effects of low-dose melami...

journal_title：Environmental toxicology

authors： Chu CY,Tang LY,Li L,Shum AS,Fung KP,Wang CC

更新日期：2017-01-01 00:00:00

abstract：:Endotoxins exist anywhere including in water pools, dust, humidifier systems, and machining fluids. The major causal factor is endotoxins in many serious diseases, such as fever, sepsis, multi-organ failure, meningococcemia, and severe morbidities like neurologic disability, or hearing loss. Endotoxins are also called...

journal_title：Environmental toxicology

authors： Huang YC,Horng CT,Chen ST,Lee SS,Yang ML,Lee CY,Kuo WH,Yeh CH,Kuan YH

更新日期：2016-02-01 00:00:00

abstract：:A 7 day in situ assay to assess sediment toxicity was carried out per replicate in two sites from Guadalete Estuary (Guad1 and Guad2) (South-West, Spain) using the polychaete Arenicola marina (n = 20) in benthic cages. After the exposure period, a battery of biomarkers were determined to asses the sediment toxicity. F...

journal_title：Environmental toxicology

authors： Ramos-Gómez J,Martín-Díaz ML,Rodríguez A,Riba I,DelValls TA

更新日期：2008-10-01 00:00:00

abstract：:Casticin, a polymethoxyflavone, is one of the major active components obtained from Fructus viticis, which have been shown to have anticancer activities including induce cell apoptosis in human cancer cells. The aim of this study was to investigate the molecular mechanisms by which casticin inhibits cell migration and...

journal_title：Environmental toxicology

authors： Shih YL,Chou HM,Chou HC,Lu HF,Chu YL,Shang HS,Chung JG

更新日期：2017-09-01 00:00:00

abstract：:Effects of perchlorate on sodium-iodide symporter (NIS) and pendrin gene expression in deer mice kidney and stomach were investigated. This was accomplished by isolating a partial cDNA sequence of deer mice NIS gene of 425 bps, and quantitatively analyzing NIS mRNA expression in various deer mouse tissues. The highest...

journal_title：Environmental toxicology

authors： Cheng Q,Smith EE,Liu F,Gentle A,Hooper MJ,Anderson TA

更新日期：2007-08-01 00:00:00

abstract：:Irradiation of polycyclic aromatic hydrocarbons (PAHs) in aqueous solution with simulated solar radiation (SSR; a light source with a visible light: UV-A:UV-B ratio similar to that of sunlight) can greatly enhance their toxicity. Two microbial toxicity tests with Vibrio fischeri were used to investigate the effect of ...

journal_title：Environmental toxicology

authors： el-Alawi YS,Dixon DG,Greenberg BM

更新日期：2001-06-01 00:00:00

abstract：:Kupffer cells (KCs) are important in hepatic homeostasis and responses to xenobiotics. KCs are activated on interaction with endotoxin, releasing cytokines, and reactive oxygen species normally associated with increased gene expression, cellular growth, or hepatic injury. Ethanol-induced endotoxemia is one means of KC...

journal_title：Environmental toxicology

authors： Owumi SE,Corthals SM,Uwaifo AO,Kamendulis LM,Klaunig JE

更新日期：2014-08-01 00:00:00

abstract：:Exposure to sublethal hexavalent chromium (as 2 and 4 mg L⁻¹ potassium dichromate for 1 and 2 months) during late preparatory to mid prespawning phase of annual reproductive cycle severely affected the pituitary-ovarian axis of a teleost Channa punctatus. Gonadosomatic index (GSI), ovarian histopathology, immunocytoch...

journal_title：Environmental toxicology

authors： Mishra AK,Mohanty B

更新日期：2012-07-01 00:00:00

abstract：:7,12-Dimethylbenz[α]anthracene (DMBA) is a hazardous component present in polluted environments. DMBA has been used as an experimental tool for in vivo tumor formation owing to its carcinogenic effects, but the detailed molecular mechanism of DMBA has not been fully established. To comprehend the carcinogenic mechanis...

journal_title：Environmental toxicology

authors： Kwon YJ,Ye DJ,Baek HS,Chun YJ

更新日期：2018-07-01 00:00:00

abstract：:Particulate matter 2.5 (PM2.5)-induced pulmonary inflammation has become a public concern in recent years. In which, the activation of the NLRP3/caspase-1 pathway was closely related to the inflammatory response of various diseases. However, the promotion effect of the NLRP3/caspase-1 pathway on PM2.5-induced pulmonar...

journal_title：Environmental toxicology

authors： Jia H,Liu Y,Guo D,He W,Zhao L,Xia S

更新日期：2020-09-30 00:00:00

abstract：:Di(2-ethylhexyl) phthalate, which is a ubiquitous environmental contaminant because of its extensive use as a plasticizer, is a potential nongenotoxic carcinogen. To assess the effects of DEHP exposure on the cytoskeleton of Chironomus, we characterized full-length cDNA sequences of the calponin gene from Chironomus r...

journal_title：Environmental toxicology

authors： Park K,Kwak IS

更新日期：2009-12-01 00:00:00

abstract：:We cloned the full-length cDNA sequence of xenobiotic metabolizing cytochrome P4501A (CYP1A) gene from the yellow catfish (Pelteobagrus fulvidraco, Siluriformes, Bagridae). P. fulvidraco is a commercially important fish generally distributed in Southeast Asian countries and Korea. This is the first report of any xenob...

journal_title：Environmental toxicology

authors： Kim JH,Hwang DS,Son KH,Raisuddin S,Ki JS,Lee JS,Han KN

更新日期：2008-06-01 00:00:00