Chronic lead exposure enhances the sympathoexcitatory response associated with P2X4 receptor in rat stellate ganglia.

abstract：:Toxicity of lead on male reproductive functions has raised wide public concern as environmental lead contamination remains common worldwide. Conflicting and controversial data are available regarding effects of lead on male fertility. More importantly, our knowledge on effects of lead on sperm DNA integrity is signifi...

journal_title：Environmental toxicology

authors： Li C,Zhao K,Zhang H,Liu L,Xiong F,Wang K,Chen B

更新日期：2018-05-01 00:00:00

abstract：:In the present study, the modulatory effect of phytol against benzo(a)pyrene [B(a)P] induced lung carcinogenesis was investigated in Swiss albino mice. During the experimental period, phytol treatment showed no adverse toxic effect and mortality to the experimental animals. Lung tumor was observed in B(a)P treated gro...

journal_title：Environmental toxicology

authors： Sakthivel R,Sheeja Malar D,Archunan G,Pandima Devi K

更新日期：2019-04-01 00:00:00

abstract：:The correlation between the content of three microcystins (types LR, RR and YR) and the cell cycle of an axenic strain of Microcystis viridis, NIES-102, was investigated under conditions of high (16 mg L(-1)) and low (1.0 mg L(-1)) nitrate (NO(3)-N) concentrations. Each phase of the cell cycle was identified using a f...

journal_title：Environmental toxicology

authors： Kameyama K,Sugiura N,Inamori Y,Maekawa T

更新日期：2004-02-01 00:00:00

abstract：:Biotransformation enzymatic activities, such as the cytochrome P450 one, have been used as biomarkers for pollution assessment for a long time. Nevertheless, such biochemical tools are destructive processes, because they are performed on fish liver or total larvae homogenates. Moreover, the adaptation of this bioassay...

journal_title：Environmental toxicology

authors： Noury P,Geffard O,Tutundjian R,Garric J

更新日期：2006-08-01 00:00:00

abstract：:Metal oxide nanoparticles and carbon nanoparticles, as common nanoparticles (NPs), can cause autophagy in certain cells, which will lead to biohealth risk issues. This study determined the difference in autophagy induced by zinc oxide nanoparticles (ZnO NPs) and single-walled carbon nanotubes (SWCNTs) in respiratory e...

journal_title：Environmental toxicology

authors： Zhang H,Chen F,Li Y,Shan X,Yin L,Hao X,Zhong Y

更新日期：2021-02-01 00:00:00

abstract：:Ouabain, a cardiotonic steroid, was used for the treatment of heart failure and atrial fibrillation and induces cancer cell apoptosis in many human cancer cells including human leukemia cells. However, there are no reports to show the effects on immune responses in a leukemia mouse model. In this study, WEHI-3 cell ge...

journal_title：Environmental toxicology

authors： Shih YL,Shang HS,Chen YL,Hsueh SC,Chou HM,Lu HF,Lee MZ,Hou HT,Chuang YY,Lee MH,Chen KW,Chung JG

更新日期：2019-05-01 00:00:00

abstract：:Casticin, a polymethoxyflavone, is one of the major active components obtained from Fructus viticis, which have been shown to have anticancer activities including induce cell apoptosis in human cancer cells. The aim of this study was to investigate the molecular mechanisms by which casticin inhibits cell migration and...

journal_title：Environmental toxicology

authors： Shih YL,Chou HM,Chou HC,Lu HF,Chu YL,Shang HS,Chung JG

更新日期：2017-09-01 00:00:00

abstract：:Manganese (Mn) plays a critical role in individual growth and development, yet excessive exposure can result in neurotoxicity, especially cognitive impairment. Neuronal apoptosis is considered as one of the mechanisms of Mn-induced neurotoxicity. Recent evidence suggests that cAMP-PKA-CREB signaling regulates apoptosi...

journal_title：Environmental toxicology

authors： Yang Y,Ma S,Wei F,Liang G,Yang X,Huang Y,Wang J,Zou Y

更新日期：2019-09-01 00:00:00

abstract：:Laboratory toxicity tests were performed to obtain more data on the toxicity of ammonia to saltwater organisms. The standards for in-stream ammonia limits in marine environments presently are based on toxicity tests involving both freshwater and saltwater organisms. Acute tests (48 and 96 h) were performed at 20 degre...

journal_title：Environmental toxicology

authors： Boardman GD,Starbuck SM,Hudgins DB,Li X,Kuhn DD

更新日期：2004-04-01 00:00:00

abstract：:An important disturbance of anthropogenic origin frequently occurring in freshwater ecosystems is a rise in the concentration of heavy metals in solution, among which copper stands out due to its known toxicity. However, the study of the chemical behavior of copper in solution is highly dependent on pH. In this study,...

journal_title：Environmental toxicology

authors： Gagneten AM,Vila I

更新日期：2001-10-01 00:00:00

abstract：:Human exposure to bisphenol A (BPA) could favor obesity and related metabolic disorders such as hepatic steatosis. Investigations in rodents have shown that these deleterious effects are observed not only when BPA is administered during the adult life but also with different protocols of perinatal exposure. Whether pe...

journal_title：Environmental toxicology

authors： Bucher S,Jalili P,Le Guillou D,Begriche K,Rondel K,Martinais S,Zalko D,Corlu A,Robin MA,Fromenty B

更新日期：2017-03-01 00:00:00

abstract：:Methoxychlor (MXC), an organochloride insecticide, is a potent toxicant-targeting female reproductive system and known to cause follicular atresia by inducing apoptosis within granulosa cells. Oxidative stress plays a pivotal role in apoptosis; thus, this study focuses on the ameliorative action of N-acetyl cysteine (...

journal_title：Environmental toxicology

authors： Bhardwaj JK,Saraf P

更新日期：2017-01-01 00:00:00

abstract：:Acetaminophen (APAP) is one of the few recommended analgesic and antipyretic drugs in some critical cases such as viral disease COVID-19. However, the unrestricted use of APAP develops liver disorders. Hepatotoxicity and liver injury can also be induced by ionizing radiation (IR) during radiotherapy. The data of the c...

journal_title：Environmental toxicology

authors： Eassawy MMT,Salem AA,Ismail AFM

更新日期：2020-12-17 00:00:00

abstract：:Adrenomedullin (AdM) is synthesized and secreted by a number of cells and tissue. AdM is a potent vasodilator but it is also considered a neuromodulator, an angiogenic factor, and a hormone regulator. AdM possess antiapoptotic, antioxidant, and antimicrobial properties. Heavy metals such as cadmium and lead are found ...

journal_title：Environmental toxicology

authors： Yurekli M,Esrefoglu M,Ilker Doğru M,Doğru A,Gul M,Whidden M

更新日期：2009-06-01 00:00:00

abstract：:Although marine and coastal environments which are contaminated with xenobiotic organic compounds often become hypoxic during the summer, the interactive effects of hypoxia and xenobiotic exposure on marine species such as teleost fishes remain poorly understood. The expression and activity of monooxygenase enzyme cyt...

journal_title：Environmental toxicology

authors： Rahman MS,Thomas P

更新日期：2018-04-01 00:00:00

abstract：:This study assessed the potential hepatoprotective effect of telmisartan (TLM), a selective angiotensin II type 1 (AT1 ) receptor blocker, on carbon tetrachloride (CCl4 )-induced acute hepatotoxity in rats. Intraperitoneal injection of male Wistar rats with CCl4 1 mL kg-1 , 1:1 mixture with corn oil for 3 days increas...

journal_title：Environmental toxicology

authors： Atawia RT,Esmat A,Elsherbiny DA,El-Demerdash E

更新日期：2017-02-01 00:00:00

abstract：:Chronic inhalation bioassays in rodents are used to assess pulmonary carcinogenicity for purposes of hazard identification and potentially for risk characterization. Numerous studies have been confirmed that exposure to titanium dioxide nanoparticles (TiO2 NPs) may result in chronic pulmonary inflammation in both mice...

journal_title：Environmental toxicology

authors： Hong F,Ji L,Zhou Y,Wang L

更新日期：2017-05-01 00:00:00

abstract：:Environmental estrogens are major cause of endocrine disruption in vertebrates, including aquatic organisms. Teleosts are valuable and popular models for studying the effects of endocrine disrupting chemicals (EDCs) in the environment. In the present study, we investigated the changes caused by exposure to the synthet...

journal_title：Environmental toxicology

authors： Sridevi P,Chaitanya RK,Prathibha Y,Balakrishna SL,Dutta-Gupta A,Senthilkumaran B

更新日期：2015-04-01 00:00:00

abstract：:So far, little is known on the distribution of hepatotoxic microcystin (MC) in various organs of bivalves, and there is no study on MC accumulation in bivalves from Chinese waters. Distribution pattern and seasonal dynamics of MC-LR, -YR and -RR in various organs (hepatopancreas, intestine, visceral mass, gill, foot, ...

journal_title：Environmental toxicology

authors： Chen J,Xie P

更新日期：2005-12-01 00:00:00

abstract：:7,12-Dimethylbenz[α]anthracene (DMBA) is a hazardous component present in polluted environments. DMBA has been used as an experimental tool for in vivo tumor formation owing to its carcinogenic effects, but the detailed molecular mechanism of DMBA has not been fully established. To comprehend the carcinogenic mechanis...

journal_title：Environmental toxicology

authors： Kwon YJ,Ye DJ,Baek HS,Chun YJ

更新日期：2018-07-01 00:00:00

abstract：:Cardiomyocyte apoptosis is the major risk factor for the development of heart failure (HF). The purpose of this study was to evaluate the effects of Gamma-aminobutyric acid (GABA) tea on hypertension-induced cardiac apoptotic pathways in spontaneously hypertensive rats (SHR). In order to reveal the mechanisms, 36 male...

journal_title：Environmental toxicology

authors： Chen BC,Hung MY,Wang HF,Yeh LJ,Pandey S,Chen RJ,Chang RL,Viswanadha VP,Lin KH,Huang CY

更新日期：2018-07-01 00:00:00

abstract：:Tributyltin (TBT) and dibutyltin (DBT) are widespread environmental contaminants found in food, beverages, and human blood samples. Both of these butyltins (BTs) interfere with the ability of human natural killer (NK) cells to lyse target cells and alter secretion of the pro-inflammatory cytokine tumor necrosis factor...

journal_title：Environmental toxicology

authors： Lawrence S,Reid J,Whalen M

更新日期：2015-05-01 00:00:00

abstract：:Culture-independent methods employed in fungal genetic studies using in vitro amplification (PCR) and analysis of specific genes or gene fragments have proved to be useful for detection, identification, and molecular taxonomy of various plant pathogens including Fusarium spp. This approach may be faster than culture-d...

journal_title：Environmental toxicology

authors： Bezuidenhout CC,Prinsloo M,Van der Walt AM

更新日期：2006-08-01 00:00:00

abstract：:Domestic exposure to biomass smoke represents the second cause of chronic obstructive lung disease. Previous studies have shown that exposure of guinea pigs to wood smoke is capable of generating oxidative stress in lung tissue, and this may involve a failure at a mitochondrial level, given its close relation with the...

journal_title：Environmental toxicology

authors： Granados-Castro LF,Rodríguez-Rangel DS,Montaño M,Ramos C,Pedraza-Chaverri J

更新日期：2015-04-01 00:00:00

abstract：:The chronic effect of p-nonylphenol on survival and reproduction for two generations of the freshwater cladoceran Daphnia galeata was examined by life table experiments. The effects on survival and reproduction were used as the intrinsic rate of natural increase, r, with the Euler-Lotka equation and were analyzed with...

journal_title：Environmental toxicology

authors： Tanaka Y,Nakanishi J

更新日期：2002-10-01 00:00:00

abstract：:2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) are persistent organic pollutants which coexist in environment, and human are co-exposed to these chemicals. Our present study was aimed to investigate the possible enhanced nonalcoholic fatty liver disease (NAFLD) in ApoE(-/-) mice co-exp...

journal_title：Environmental toxicology

authors： Shan Q,Huang F,Wang J,Du Y

更新日期：2015-12-01 00:00:00

abstract：:Polybrominated diphenyl ethers (PBDEs) are ubiquitous and prolific contaminant in both the abiotic and biotic environment because of the wide industrial applications of these chemicals. In the present study, the effects of 2,2',4,4'-tetrabrominateddiphenyl ether (BDE-47) and 2,2',4,4',5,5'-hexabromodiphenyl ether (BDE...

journal_title：Environmental toxicology

authors： Meng S,Chen X,Gyimah E,Xu H,Chen J

更新日期：2020-11-01 00:00:00

abstract：:The toxicity of petroleum hydrocarbons to marine aquatic organisms has been widely investigated; however, the effects on freshwater environments have largely been ignored. Selected biomarkers were measured in a freshwater species, the crimson-spotted rainbowfish (Melanotaenia fluviatilis). Fish were exposed to either ...

journal_title：Environmental toxicology

authors： Pollino CA,Holdway DA

更新日期：2003-02-01 00:00:00

abstract：:Hexavalent chromium (CrVI) is a highly toxic metal and a major environmental pollutant. Several studies indicate that CrVI exposure adversely affects reproductive function. We reported that maternal Cr exposure resulted in Cr accumulation in the reproductive organs of female offsprings. CrVI can cross the placental ba...

journal_title：Environmental toxicology

authors： Samuel JB,Stanley JA,Sekar P,Princess RA,Sebastian MS,Aruldhas MM

更新日期：2014-05-01 00:00:00

abstract：:Survival of juvenile freshwater mussels (Echyridella menziesii (Gray, 1843) formerly known as Hyridella menziesi) and crayfish (Paranephrops planifrons, White, 1842) decreased after four days exposure to microcystin-containing cell-free extracts (MCFE) of Microcystis sp. at concentrations typical of severe cyanobacter...

journal_title：Environmental toxicology

authors： Clearwater SJ,Wood SA,Phillips NR,Parkyn SM,Van Ginkel R,Thompson KJ

更新日期：2014-05-01 00:00:00