Persistent hexavalent chromium exposure impaired the pubertal development and ovarian histoarchitecture in wistar rat offspring.

abstract：:Effect-directed analysis (EDA) has been reported to be a powerful tool for the identification of the responsible toxicants in contaminated, hazardous environmental samples. The aim of this study was to investigate whether it also is possible to use currently available EDA methodology to identify potentially relevant t...

journal_title：Environmental toxicology

authors： Grote M,Brack W,Altenburger R

更新日期：2005-10-01 00:00:00

abstract：:Bisphenol A (BPA) has been widely reported to exert endocrine disrupting effects, including the induction of adipogenesis in cultured preadipocytes and intact animals. Because of the potential harm to human health, BPA is being substituted by structurally related bisphenols. Whether or not such BPA analogues are safe ...

journal_title：Environmental toxicology

authors： Ramskov Tetzlaff CN,Svingen T,Vinggaard AM,Rosenmai AK,Taxvig C

更新日期：2020-05-01 00:00:00

abstract：:Chlorpyrifos (CPF) is one of the most widely used organophosphorus, which has spurred renewed interest. This study was conducted to investigate the protective effect of ziziphora tenuior extract against CPF-induced liver and lung toxicity. This study conducted 8-week rat sub-chronic toxicity study and then the effect ...

journal_title：Environmental toxicology

authors： Yazdinezhad A,Abbasian M,Hojjat Hosseini S,Naserzadeh P,Agh-Atabay AH,Hosseini MJ

更新日期：2017-09-01 00:00:00

abstract：:Phenols are environmentally important compounds that are widely used in agriculture and industry. Thus, phenols are of interest to environmental toxicologists, which has led to the development of several quantitative structure-activity relationship (QSAR) models. The most successful QSARs have been established for com...

journal_title：Environmental toxicology

authors： Ren S

更新日期：2002-01-01 00:00:00

abstract：:Particulate matter 2.5 (PM2.5)-induced pulmonary inflammation has become a public concern in recent years. In which, the activation of the NLRP3/caspase-1 pathway was closely related to the inflammatory response of various diseases. However, the promotion effect of the NLRP3/caspase-1 pathway on PM2.5-induced pulmonar...

journal_title：Environmental toxicology

authors： Jia H,Liu Y,Guo D,He W,Zhao L,Xia S

更新日期：2020-09-30 00:00:00

abstract：:Previous studies indicate that exposure to perfluorooctanesulfonate (PFOS), a ubiquitous and highly persistent environmental contaminant, induces immunotoxicity in mice. However, few studies have specifically assessed the effects of PFOS on inflammation. This study utilized a standard 60-day oral exposure period to as...

journal_title：Environmental toxicology

authors： Dong GH,Zhang YH,Zheng L,Liang ZF,Jin YH,He QC

更新日期：2012-05-01 00:00:00

abstract：:Fluoride exposure is widespread, with drinking water commonly containing natural and artificially added sources of the ion. Ingested fluoride undergoes absorption across the gastric and intestinal epithelia. Previous studies have reported adverse gastrointestinal effects with high levels of fluoride exposure. Here, we...

journal_title：Environmental toxicology

authors： Amadeu de Oliveira F,MacVinish LJ,Amin S,Herath D,Jeggle P,Mela I,Pieri M,Sharma C,Jarvis GE,Levy FM,Santesso MR,Khan ZN,Leite AL,Oliveira RC,Buzalaf MAR,Edwardson JM

更新日期：2018-01-01 00:00:00

abstract：:As a widely used plasticizer in industry, di-2-ethylhexylphthalate (DEHP) can cause testicular toxicity, yet little is known about the potential mechanism. In this study, DEHP exposure dramatically inhibited cellviability and induced apoptosis of mouse GC-1 spg cells. Furthermore, DEHP significantly increased the leve...

journal_title：Environmental toxicology

authors： Gan Y,Yang D,Yang S,Wang J,Wei J,Chen J

更新日期：2020-02-01 00:00:00

abstract：:A 7 day in situ assay to assess sediment toxicity was carried out per replicate in two sites from Guadalete Estuary (Guad1 and Guad2) (South-West, Spain) using the polychaete Arenicola marina (n = 20) in benthic cages. After the exposure period, a battery of biomarkers were determined to asses the sediment toxicity. F...

journal_title：Environmental toxicology

authors： Ramos-Gómez J,Martín-Díaz ML,Rodríguez A,Riba I,DelValls TA

更新日期：2008-10-01 00:00:00

abstract：:2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) are persistent organic pollutants which coexist in environment, and human are co-exposed to these chemicals. Our present study was aimed to investigate the possible enhanced nonalcoholic fatty liver disease (NAFLD) in ApoE(-/-) mice co-exp...

journal_title：Environmental toxicology

authors： Shan Q,Huang F,Wang J,Du Y

更新日期：2015-12-01 00:00:00

abstract：:Sick building syndrome (SBS) is a set of several clinically recognizable symptoms reported by occupants of a building without a clear cause. Neuropathy target esterase (NTE) is a membrane bound serine esterase and its reaction with organophosphates (OPs) can lead to OP-induced delayed neuropathy (OPIDN) and nerve axon...

journal_title：Environmental toxicology

authors： Matsuzaka Y,Ohkubo T,Kikuti YY,Mizutani A,Tsuda M,Aoyama Y,Kakuta K,Oka A,Inoko H,Sakabe K,Ishikawa S,Kulski JK,Kimura M

更新日期：2014-10-01 00:00:00

abstract：:Dibutyltin (DBT) is the degradation products of TBT, which is generally considered higher toxicity than TBT in the immune system. In order to learn more about the mechanisms of immune-toxic of DBT, we exposed zebrafish (Danio rerio) to 0, 1, 10 and 100 ng/L DBT for 8 weeks. At the end of the experiment, we determined ...

journal_title：Environmental toxicology

authors： Zhang CN,Zhang JL,Huang Y,Ren HT,Guan SH,Zeng QH

更新日期：2018-01-01 00:00:00

abstract：:Culture-independent methods employed in fungal genetic studies using in vitro amplification (PCR) and analysis of specific genes or gene fragments have proved to be useful for detection, identification, and molecular taxonomy of various plant pathogens including Fusarium spp. This approach may be faster than culture-d...

journal_title：Environmental toxicology

authors： Bezuidenhout CC,Prinsloo M,Van der Walt AM

更新日期：2006-08-01 00:00:00

abstract：:Within the last decade, numerous epidemiological studies have demonstrated that endocrine disruptors are a possible cause for a decline in semen quality. Cypermethrin is a widely used pyrethroid insecticide, but little is known about its potentially adverse effects on male reproduction. In the present study, we invest...

journal_title：Environmental toxicology

authors： Wang H,Wang SF,Ning H,Ji YL,Zhang C,Zhang Y,Yu T,Ma XH,Zhao XF,Wang Q,Liu P,Meng XH,Xu DX

更新日期：2011-08-01 00:00:00

abstract：:Trichloroethylene (TCE) is ubiquitous in our living environment, and prenatal exposure to TCE is reported to cause congenital heart disease in humans. Although multiple studies have been performed using animal models, they have limited value in predicting effects on humans due to the unknown species-specific toxicolog...

journal_title：Environmental toxicology

authors： Jiang Y,Wang D,Zhang G,Wang G,Tong J,Chen T

更新日期：2016-11-01 00:00:00

abstract：:Malathion is one of the most commonly used insecticides. Recent findings have demonstrated that it induces oxidative stress in somatic cells, but there are not enough studies that have demonstrated this effect in germ cells. Malathion impairs porcine oocyte viability and maturation, but studies have not shown how oxid...

journal_title：Environmental toxicology

authors： Flores D,Souza V,Betancourt M,Teteltitla M,González-Márquez H,Casas E,Bonilla E,Ramírez-Noguera P,Gutiérrez-Ruíz MC,Ducolomb Y

更新日期：2017-06-01 00:00:00

abstract：:In this study, toxic effects of the cypermethrin in Allium cepa L. cells were investigated. For this aim, we investigated the changes in pigment contents, antioxidant enzymes, mitotic index and chromosomal abnormalities as indicators of toxicity. The seeds were treated with different doses (1.5, 3.0, 6.0 ppm) of cyper...

journal_title：Environmental toxicology

authors： Çavuşoğlu K,Kaya A,Yilmaz F,Yalçin E

更新日期：2012-10-01 00:00:00

abstract：:Dicrotophos is a systemic insecticide with a wide range of applications. We investigated the genotoxicity of dicrotophos using the Ames test, the chromosome aberration test in CHO-K1 cells, and the comet assay in the Hep G2 cells, while this chemicals' toxicity to both the cell lines was evaluated with the MTT assay. ...

journal_title：Environmental toxicology

authors： Wu JC,Chye SM,Shih MK,Chen CH,Yang HL,Chen SC

更新日期：2012-05-01 00:00:00

abstract：:Lake Elphinstone is a tropical inland water body in the far north of the Fitzroy Catchment in Central Queensland, Australia, and has experienced recurrent toxic cyanoprokaryote blooms since 1997. This article reports on an examination of the environmental conditions of the lake and the concurrent cyanoprokaryote speci...

journal_title：Environmental toxicology

authors： White SH,Fabbro LD,Duivenvoorden LJ

更新日期：2003-12-01 00:00:00

abstract：:Airborne particulates, especially fine particles and bound chemical compounds, are a potential mediator of adverse health effects. In this study an analysis was done of the concentration and size distribution of air particulate matter, the content of bound polycyclic aromatic hydrocarbons (PAHs), and the biological ef...

journal_title：Environmental toxicology

authors： Massolo L,Müller A,Tueros M,Rehwagen M,Franck U,Ronco A,Herbarth O

更新日期：2002-01-01 00:00:00

abstract：:Being one of the notorious weed P. hysterophorus has invaded almost every part India and is the lead cause of skin allergies and severe dermatitis among farmers and rural population. It is an invasive obnoxious weed capable of surviving extreme environmental conditions and various parts of this plant are reported to c...

journal_title：Environmental toxicology

authors： Kaur M,Gupta KB,Thakur S,Kaur S,Dhiman M

更新日期：2020-11-01 00:00:00

abstract：:The acute toxicity of cylindrospermopsin (CYN) has been established in rodents, based on diverse intraperitoneal an oral exposure studies and more recently in fish. But no data have been reported in fish after subchronic exposure to cyanobacterial cells containing this cyanotoxin, so far. In this work, tilapia (Oreoch...

journal_title：Environmental toxicology

authors： Guzmán-Guillén R,Prieto AI,Moreno I,Vasconcelos VM,Moyano R,Blanco A,Cameán Fernandez AM

更新日期：2015-03-01 00:00:00

abstract：:The prostate is an accessory reproductive gland that is sensitive to the action of exogenous compounds known as endocrine disrupters that alter normal hormonal function. Finasteride is a widely used chemical that acts to inhibit the conversion of testosterone in its most active form, dihydrotestosterone. It is known t...

journal_title：Environmental toxicology

authors： Maldarine JS,Sanches BDA,Santos VA,Amaro GM,Calmon MF,Rahal P,Góes RM,Vilamaior PSL,Taboga SR

更新日期：2020-01-01 00:00:00

abstract：:Smoking increases the risk of cardiovascular disorders and leads to damage caused by inflammation and oxidative stress. The actin cytoskeleton is a key player in the response to inflammatory stimuli and is an early target of cellular oxidative stress. The purpose of this study was to investigate the changes in actin c...

journal_title：Environmental toxicology

authors： Lin BH,Tsai MH,Lii CK,Wang TS

更新日期：2016-11-01 00:00:00

abstract：:In the present study, responses of the Chinese brown frog (Rana chensinensis) to exposure to di-2-ethylhexyl phthalate (DEHP), a common plasticizer, during the larval period were characterized. The effects of DEHP on metamorphosis rate, thyroid hormone, thyroid histology and the expression of genes involved in the ste...

journal_title：Environmental toxicology

authors： Zhang Y,Li X,Gao J,Wang H

更新日期：2018-01-01 00:00:00

abstract：:Methoxychlor (MXC), an organochloride insecticide, is a potent toxicant-targeting female reproductive system and known to cause follicular atresia by inducing apoptosis within granulosa cells. Oxidative stress plays a pivotal role in apoptosis; thus, this study focuses on the ameliorative action of N-acetyl cysteine (...

journal_title：Environmental toxicology

authors： Bhardwaj JK,Saraf P

更新日期：2017-01-01 00:00:00

abstract：:The chronic effect of p-nonylphenol on survival and reproduction for two generations of the freshwater cladoceran Daphnia galeata was examined by life table experiments. The effects on survival and reproduction were used as the intrinsic rate of natural increase, r, with the Euler-Lotka equation and were analyzed with...

journal_title：Environmental toxicology

authors： Tanaka Y,Nakanishi J

更新日期：2002-10-01 00:00:00

abstract：:Doxorubicin (DOX)-induced cardiomyopathy is a lethal disease. DOX-induced cardiotoxic effects are attributed towards increased redox status and apoptotic signaling. In this study, we show that genistein offers protection against DOX-induced cardio toxicity in the mice model. DOX-mediated increase in serum cardiac trop...

journal_title：Environmental toxicology

authors： Bai Z,Wang Z

更新日期：2019-05-01 00:00:00

abstract：:The mycotoxin citrinin (CTN), a natural contaminant in foodstuffs and animal feeds, exerts cytotoxic and genotoxic effects on various mammalian cells. CTN causes cell injury, including apoptosis. Previous studies by our group showed that CTN triggers apoptosis in mouse embryonic stem cells, as well as embryonic develo...

journal_title：Environmental toxicology

authors： Huang YT,Lai CY,Lou SL,Yeh JM,Chan WH

更新日期：2009-08-01 00:00:00

abstract：:Indium, a rare earth metal characterized by high plasticity, corrosion resistance, and a low melting point, is widely used in the electronics industry, but has been reported to be an environmental pollutant and a health hazard. We designed a study to investigate the effects of subacute exposure of indium compounds on ...

journal_title：Environmental toxicology

authors： Lee KH,Chen HL,Leung CM,Chen HP,Hsu PC

更新日期：2016-01-01 00:00:00