Internal and external validity of cluster randomised trials: systematic review of recent trials.

abstract：OBJECTIVE:To evaluate the association between consumption of ultra-processed foods and all cause mortality. DESIGN:Prospective cohort study. SETTING:Seguimiento Universidad de Navarra (SUN) cohort of university graduates, Spain 1999-2018. PARTICIPANTS:19 899 participants (12 113 women and 7786 men) aged 20-91 years ...

journal_title：BMJ (Clinical research ed.)

authors： Rico-Campà A,Martínez-González MA,Alvarez-Alvarez I,Mendonça RD,de la Fuente-Arrillaga C,Gómez-Donoso C,Bes-Rastrollo M

更新日期：2019-05-29 00:00:00

abstract：OBJECTIVE:To investigate whether paracetamol (acetaminophen) plus ibuprofen are superior to either drug alone for increasing time without fever and the relief of fever associated discomfort in febrile children managed at home. DESIGN:Individually randomised, blinded, three arm trial. SETTING:Primary care and househol...

journal_title：BMJ (Clinical research ed.)

authors： Hay AD,Costelloe C,Redmond NM,Montgomery AA,Fletcher M,Hollinghurst S,Peters TJ

更新日期：2008-09-02 00:00:00

abstract：:The rapid aging of populations in developing countries as compared to those in the developed world has implications for medical training in these places. Moreover, the growing globalization of employment for many health professionals means that demographic shifts have implications for the training of health professio...

journal_title：BMJ (Clinical research ed.)

authors： Ebrahim S

更新日期：1999-11-20 00:00:00

abstract：OBJECTIVE:To determine if the Food Standards Agency nutrient profiling system (FSAm-NPS), which grades the nutritional quality of food products and is used to derive the Nutri-Score front-of-packet label to guide consumers towards healthier food choices, is associated with mortality. DESIGN:Population based cohort stu...

journal_title：BMJ (Clinical research ed.)

authors： Deschasaux M,Huybrechts I,Julia C,Hercberg S,Egnell M,Srour B,Kesse-Guyot E,Latino-Martel P,Biessy C,Casagrande C,Murphy N,Jenab M,Ward HA,Weiderpass E,Overvad K,Tjønneland A,Rostgaard-Hansen AL,Boutron-Ruault MC,Manc

更新日期：2020-09-16 00:00:00

abstract：OBJECTIVE:To assess the effects of Helicobacter pylori treatment, vitamin supplementation, and garlic supplementation in the prevention of gastric cancer. DESIGN:Blinded randomized placebo controlled trial. SETTING:Linqu County, Shandong province, China. PARTICIPANTS:3365 residents of a high risk region for gastric ...

journal_title：BMJ (Clinical research ed.)

authors： Li WQ,Zhang JY,Ma JL,Li ZX,Zhang L,Zhang Y,Guo Y,Zhou T,Li JY,Shen L,Liu WD,Han ZX,Blot WJ,Gail MH,Pan KF,You WC

更新日期：2019-09-11 00:00:00

abstract：OBJECTIVE:This study updates work published in 1998, which found that of 47 rating instruments appearing on websites offering health information, 14 described how they were developed, five provided instructions for use, and none reported the interobserver reliability and construct validity of the measurements. DESIGN:...

journal_title：BMJ (Clinical research ed.)

authors： Gagliardi A,Jadad AR

更新日期：2002-03-09 00:00:00

abstract：OBJECTIVE:To investigate the risk factors for HIV infection in patients attending clinics for sexually transmitted diseases in India. DESIGN:Descriptive study of HIV serology, risk behaviour, and findings on physical examination. SUBJECTS:2800 patients presenting to outpatient clinics between 13 May 1993 and 15 July ...

journal_title：BMJ (Clinical research ed.)

authors： Rodrigues JJ,Mehendale SM,Shepherd ME,Divekar AD,Gangakhedkar RR,Quinn TC,Paranjape RS,Risbud AR,Brookmeyer RS,Gadkari DA

更新日期：1995-07-29 00:00:00

abstract：:I have attempted to adopt the perspective of a patient--albeit one with a rather atypical background--to explore what I want from health research and researchers. This has left me with the impression that health researchers could serve the interests of the public more effectively in a variety of ways, and that they wo...

journal_title：BMJ (Clinical research ed.)

authors： Chalmers I

更新日期：1995-05-20 00:00:00

abstract：OBJECTIVE:To characterise the functional morphology of the nasal microcirculation in humans in comparison with reindeer as a means of testing the hypothesis that the luminous red nose of Rudolph, one of the most well known reindeer pulling Santa Claus's sleigh, is due to the presence of a highly dense and rich nasal mi...

journal_title：BMJ (Clinical research ed.)

authors： Ince C,van Kuijen AM,Milstein DM,Yürük K,Folkow LP,Fokkens WJ,Blix AS

更新日期：2012-12-14 00:00:00

abstract：OBJECTIVE:To evaluate the clinical benefit of lipid lowering drug treatment in patients with and without diabetes mellitus, for primary and secondary prevention. DESIGN:Systematic review and meta-analysis. DATA SOURCES:Cochrane, Medline, Embase, and reference lists up to April 2004. STUDY SELECTION:Randomised, place...

journal_title：BMJ (Clinical research ed.)

authors： Costa J,Borges M,David C,Vaz Carneiro A

更新日期：2006-05-13 00:00:00

abstract：OBJECTIVE:To assess whether a strategy of endovascular repair (if aortic morphology is suitable, open repair if not) versus open repair reduces early mortality for patients with suspected ruptured abdominal aortic aneurysm. DESIGN:Randomised controlled trial. SETTING:30 vascular centres (29 UK, 1 Canadian), 2009-13. ...

journal_title：BMJ (Clinical research ed.)

authors： IMPROVE Trial Investigators.,Powell JT,Sweeting MJ,Thompson MM,Ashleigh R,Bell R,Gomes M,Greenhalgh RM,Grieve R,Heatley F,Hinchliffe RJ,Thompson SG,Ulug P

更新日期：2014-01-13 00:00:00

abstract：:Robots designed for surgery have three main advantages over humans. They have greater three dimensional spatial accuracy, are more reliable, and can achieve much greater precision. Although few surgical robots are yet in clinical trials one or two have advanced to the stage of seeking approval from the UK's Medical De...

journal_title：BMJ (Clinical research ed.)

authors： Buckingham RA,Buckingham RO

更新日期：1995-12-02 00:00:00

abstract：:Eleven euthyroid patients with severe Graves' eye disease were treated with intravenous methylprednisolone and followed up for six months or more by ophthalmological assessment, orbital computed tomography (CT), photographs, and antibody measurements. Papilloedema resolved in the single patient in whom it was present;...

journal_title：BMJ (Clinical research ed.)

authors： Kendall-Taylor P,Crombie AL,Stephenson AM,Hardwick M,Hall K

更新日期：1988-12-17 00:00:00

abstract：OBJECTIVE:To assess the association of lichen planus with liver complaints and with known aetiological factors of liver diseases. DESIGN:Multicentre case-control study. Interviews were conducted by trained medical investigators on the basis of a structured questionnaire. At the interview patients and controls were ask...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1990-01-27 00:00:00

abstract：:Hepatorenal syndrome (HRS), the extreme manifestation of renal impairment in patients with cirrhosis, is characterized by reduction in renal blood flow and glomerular filtration rate. Hepatorenal syndrome is diagnosed when kidney function is reduced but evidence of intrinsic kidney disease, such as hematuria, proteinu...

journal_title：BMJ (Clinical research ed.)

authors： Simonetto DA,Gines P,Kamath PS

更新日期：2020-09-14 00:00:00

abstract：:The World Health Organization's (WHO) definition of health as "a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity" had the merit of widening concepts of health to include psychological and social aspects, but is of no practical use. In fact, this statement m...

journal_title：BMJ (Clinical research ed.)

authors： Saracci R

更新日期：1997-05-10 00:00:00

abstract：OBJECTIVES:To determine the prevalence of drug and alcohol use among newly remanded prisoners, assess the effectiveness of prison reception screening, and examine the clinical management of substance misusers among remand prisoners. DESIGN:A consecutive case study of remand prisoners screened at reception for substanc...

journal_title：BMJ (Clinical research ed.)

authors： Mason D,Birmingham L,Grubin D

更新日期：1997-07-05 00:00:00

abstract：OBJECTIVE:To identify additional factors, such as maternal age or factors related to previous reproductive outcome or family history, and the corresponding probability of carrying a chromosome abnormality in couples with two or more miscarriages. DESIGN:Nested case-control study. SETTING:Six centres for clinical gene...

journal_title：BMJ (Clinical research ed.)

authors： Franssen MT,Korevaar JC,Leschot NJ,Bossuyt PM,Knegt AC,Gerssen-Schoorl KB,Wouters CH,Hansson KB,Hochstenbach R,Madan K,van der Veen F,Goddijn M

更新日期：2005-07-16 00:00:00

abstract：OBJECTIVES:To investigate the effect of milk supplementation on total body bone mineral acquisition in adolescent girls. DESIGN:18 month, open randomised intervention trial. SUBJECTS:82 white girls aged 12.2 (SD 0.3) years, recruited from four secondary schools in Sheffield. INTERVENTION:568 ml (one pint) of whole o...

journal_title：BMJ (Clinical research ed.)

authors： Cadogan J,Eastell R,Jones N,Barker ME

更新日期：1997-11-15 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of teaching general practitioners skills in brief cognitive behaviour therapy. DESIGN:Parallel group, cluster randomised, controlled trial of an educational package on cognitive behaviour therapy. SETTING:General practices in north London. PARTICIPANTS:84 general practitioner pr...

journal_title：BMJ (Clinical research ed.)

authors： King M,Davidson O,Taylor F,Haines A,Sharp D,Turner R

更新日期：2002-04-20 00:00:00

abstract：OBJECTIVE:To assess the impact of construction of microdams on the incidence of malaria in nearby communities in terms of possibly increasing peak incidence and prolonging transmission. DESIGN:Four quarterly cycles of malaria incidence surveys, each taking 30 days, undertaken in eight at risk communities close to dams...

journal_title：BMJ (Clinical research ed.)

authors： Ghebreyesus TA,Haile M,Witten KH,Getachew A,Yohannes AM,Yohannes M,Teklehaimanot HD,Lindsay SW,Byass P

更新日期：1999-09-11 00:00:00

abstract：OBJECTIVE:To compare the effect on prevalence of diarrhoea and mortality of household based treatment of drinking water with flocculant-disinfectant, sodium hypochlorite, and standard practices in areas with turbid water source in Africa. DESIGN:Cluster randomised controlled trial over 20 weeks. SETTING:Family compou...

journal_title：BMJ (Clinical research ed.)

authors： Crump JA,Otieno PO,Slutsker L,Keswick BH,Rosen DH,Hoekstra RM,Vulule JM,Luby SP

更新日期：2005-09-03 00:00:00

abstract：OBJECTIVE:To identify historical and clinical findings at emergency department presentation associated with severe H1N1 outcome in children presenting with influenza-like illness. DESIGN:Multicentre retrospective case-control study. SETTING:79 emergency departments of hospitals associated with the Pediatric Emergency...

journal_title：BMJ (Clinical research ed.)

authors： Dalziel SR,Thompson JM,Macias CG,Fernandes RM,Johnson DW,Waisman Y,Cheng N,Acworth J,Chamberlain JM,Osmond MH,Plint A,Valerio P,Black KJ,Fitzpatrick E,Newton AS,Kuppermann N,Klassen TP,Pediatric Emergency Research Netwo

更新日期：2013-08-12 00:00:00

abstract：OBJECTIVES:To determine the effectiveness of tai chi interventions compared with aerobic exercise, a current core standard treatment in patients with fibromyalgia, and to test whether the effectiveness of tai chi depends on its dosage or duration. DESIGN:Prospective, randomized, 52 week, single blind comparative effec...

journal_title：BMJ (Clinical research ed.)

authors： Wang C,Schmid CH,Fielding RA,Harvey WF,Reid KF,Price LL,Driban JB,Kalish R,Rones R,McAlindon T

更新日期：2018-03-21 00:00:00

abstract：:Environmental issues tend to greater political attention than do environmental health aspects. Therefore, when conflicts of interest occur with other environmental concerns, negative consequences for public health may result. For example, a strategy to substantially reduce indoor ventilation in many dwellings in Sca...

journal_title：BMJ (Clinical research ed.)

authors： Pershagen G

更新日期：1999-06-19 00:00:00

abstract：OBJECTIVE:To estimate the risk of having a low birthweight infant associated with changes in social, environmental, and genetic factors. DESIGN:Population based, historical cohort study using the Danish medical birth registry and Statistic Denmark's fertility database. SUBJECTS:All women who had a low birthweight inf...

journal_title：BMJ (Clinical research ed.)

authors： Basso O,Olsen J,Johansen AM,Christensen K

更新日期：1997-12-06 00:00:00

abstract：OBJECTIVE:To compare blood pressure control, satisfaction, and adherence to drug treatment in patients with treated hypertension followed up by their family physicians either every three months or every six months for three years. DESIGN:Randomised equivalence clinical trial. Settings 50 family practices in south east...

journal_title：BMJ (Clinical research ed.)

authors： Birtwhistle RV,Godwin MS,Delva MD,Casson RI,Lam M,MacDonald SE,Seguin R,Rühland L

更新日期：2004-01-24 00:00:00

abstract：:The results of the work of the Edinburgh Rehabilitation Medicine Service in one year were evaluated. Over 1400 new patients were seen, of whom 525 were in hospital at the time. Patients most often referred were those who had had cardiovascular accidents, back pain, lower limb amputations, and head injuries and those c...

journal_title：BMJ (Clinical research ed.)

authors： Roy CW,Arthurs Y,Hunter J,Parker S,McLaren A

更新日期：1988-09-03 00:00:00

abstract：OBJECTIVES:To quantify the relative contribution of premorbid and episode specific factors in determining the long term persistence of disabling symptoms of low back pain. DESIGN:Prospective cohort study. SETTING:Two general practices in the south Manchester area. PARTICIPANTS:180 patients, who previously participat...

journal_title：BMJ (Clinical research ed.)

authors： Thomas E,Silman AJ,Croft PR,Papageorgiou AC,Jayson MI,Macfarlane GJ

更新日期：1999-06-19 00:00:00

abstract：:Lung cancer, the most prevalent cancer in the Western world, is mainly caused by smoking. Nevertheless, only 20% of smokers develop lung cancer and while prevention is important, environmental factors are expected to contribute to the predicted rise in the incidence of lung cancer in the next 25 years. Survival of lun...

journal_title：BMJ (Clinical research ed.)

authors： Sethi T

更新日期：1997-03-01 00:00:00