Cytoadherence characteristics of rosette-forming Plasmodium falciparum.

abstract：:The lack of specific T-cell help in immune responses to thymus-independent antigens results in weak, predominantly immunoglobulin M-mediated immunity with little or no memory. In the work presented here we show how the exogenous stimulation of CD40 by monoclonal antibodies can mimic T-cell help, resulting in enhanced ...

journal_title：Infection and immunity

authors： Barr TA,Heath AW

更新日期：1999-07-01 00:00:00

abstract：:The hallmarks of enteropathogenic Escherichia coli (EPEC) infection are formation of attaching and effacing (A/E) lesions on mucosal surfaces and actin-rich pedestals on cultured cells, both of which are dependent on the type III secretion system effector Tir. Following translocation into cultured cells and clustering...

journal_title：Infection and immunity

authors： Crepin VF,Habibzay M,Glegola-Madejska I,Guenot M,Collins JW,Frankel G

更新日期：2015-09-01 00:00:00

abstract：:Oral administration of polymyxin to specific-pathogen-free C3H/Law mice which with previously contaminated with gram-negative bacteria resulted in complete suppression of cecal gram-negative bacteria. Suppression of cecal gram-negative bacteria was accompanied by reduction of the cecal endotoxin concentration from 10 ...

journal_title：Infection and immunity

authors： Goris H,de Boer F,van der Waaij D

更新日期：1985-11-01 00:00:00

abstract：:The plasma level of the chemokine CCL3 is elevated in patients with chronic severe schistosomiasis mansoni. We have previously shown that CCL3(-/-) mice with experimental infection showed diminished pathology and worm burden compared to those of wild-type (WT) mice. To elucidate further the role of CC chemokines durin...

journal_title：Infection and immunity

authors： Souza AL,Souza PR,Pereira CA,Fernandes A,Guabiraba R,Russo RC,Vieira LQ,Corrêa A Jr,Teixeira MM,Negrão-Corrêa D

更新日期：2011-04-01 00:00:00

abstract：:Lipid extracts derived from a group A Streptococcus, when preincubated with tumor cells before inoculation, were shown to prevent completely the development of Ehrlich ascites tumor in mice. ...

journal_title：Infection and immunity

authors： Kigoshi S

更新日期：1971-05-01 00:00:00

abstract：:Pulmonary washings from rabbits were freed of cells and added to the monolayers of homologous alveolar macrophages (AM). At 1 h after incubation with the pulmonary washings, many more cells adhered to glass, spread out, and showed enhanced Nitro Blue Tetrazolium reduction. The maximal effect of the pulmonary washings ...

journal_title：Infection and immunity

authors： Ando M,Suga M,Shima K,Sugimoto M,Tokuomi H

更新日期：1978-05-01 00:00:00

abstract：:Changes in cell viability and in factors affecting metabolic integrity were examined after exposure of Escherichia coli LP1092 to human serum. Antibody-dependent classical pathway activity accounted for the rapid killing of strain LP1092 by complement. Removal of serum lysozyme by bentonite absorption or by neutraliza...

journal_title：Infection and immunity

authors： Taylor PW,Kroll HP

更新日期：1983-01-01 00:00:00

abstract：:The adherence and aggregation properties of 46 human oral Streptococcus salivarius isolates were examined. A total of 41% of the isolates aggregated with whole human saliva, 50% aggregated with human erythrocytes, and 85% adhered to human buccal epithelial cells. Strains that aggregated with saliva and erythrocytes us...

journal_title：Infection and immunity

authors： Weerkamp AH,McBride BC

更新日期：1980-08-01 00:00:00

abstract：:Ehrlichia chaffeensis and Anaplasma phagocytophilum are agents of human monocytic and granulocytic ehrlichioses, respectively. They are extremely sensitive to mechanical stress and are pleomorphic gram-negative bacteria. Membrane incorporation of cholesterol from the eukaryotic host is known to be essential for other ...

journal_title：Infection and immunity

authors： Lin M,Rikihisa Y

更新日期：2003-09-01 00:00:00

abstract：:Clostridium perfringens is an anaerobic, Gram-positive bacterium that causes a range of diseases in humans, including lethal gas gangrene. We have recently shown that strains of C. perfringens move across the surface of agar plates by a unique type IV pilus (TFP)-mediated social motility that had not been previously d...

journal_title：Infection and immunity

authors： Rodgers K,Arvidson CG,Melville S

更新日期：2011-08-01 00:00:00

abstract：:F1651 and the pyelonephritis-associated pili (Pap) are two members of the type P family of adhesive factors. They play a key role in establishing disease caused by extraintestinal pathogenic Escherichia coli (ExPEC) strains in animals and humans. Both F1651 and Pap are under the control of an epigenetic and reversible...

journal_title：Infection and immunity

authors： Graveline R,Lavoie R,Garneau P,Daigle F,Sénéchal S,Martin C,Harel J

更新日期：2015-05-01 00:00:00

abstract：:Pasteurella (Mannheimia) haemolytica leukotoxin (Lkt) causes cell type- and species-specific effects in ruminant leukocytes. Recent studies indicate that P. haemolytica Lkt binds to bovine CD18, the common subunit of all beta2 integrins. We designed experiments with the following objectives: to identify which member o...

journal_title：Infection and immunity

authors： Jeyaseelan S,Hsuan SL,Kannan MS,Walcheck B,Wang JF,Kehrli ME,Lally ET,Sieck GC,Maheswaran SK

更新日期：2000-01-01 00:00:00

abstract：:Representative strains of serogroup A Neisseria meningitidis were chosen from all major meningitis epidemics worldwide since 1960 and subjected to analysis for the electrophoretic variation of 15 cytoplasmic allozymes and four outer membrane proteins. The 290 strains defined 84 unique electrophoretic types which were ...

journal_title：Infection and immunity

authors： Wang JF,Caugant DA,Li X,Hu X,Poolman JT,Crowe BA,Achtman M

更新日期：1992-12-01 00:00:00

abstract：:Vibrio cholerae is a monoflagellated gram-negative bacterium that causes the severe diarrheal disease cholera. In contrast to Salmonella enterica serovar Typhimurium infection, which is accompanied by both acute diarrhea and high-level inflammation, V. cholerae infection is largely noninflammatory in human hosts. Bact...

journal_title：Infection and immunity

authors： Yoon SS,Mekalanos JJ

更新日期：2008-03-01 00:00:00

abstract：:Adult volunteers received a booster dose (4 x 10(8) CFU) of attenuated Vibrio cholerae CVD 103-HgR oral vaccine 15 or 24 months after primary immunization. The immune response was modest, presumably due to rapid clearance of the vaccine strain by a primed immune system. ...

journal_title：Infection and immunity

authors： Cryz SJ Jr,Levine MM,Losonsky G,Kaper JB,Althaus B

更新日期：1992-09-01 00:00:00

abstract：:Monoclonal antibodies have been generated to the unique distal sugar epitopes on the oligosaccharide haptens of the glycopeptidolipid antigens of clinically prominent members of the Mycobacterium avium serocomplex. Thus, antibodies are described that recognize the distal O-acetyl-alpha-L-rhamnopyranosyl residue of the...

journal_title：Infection and immunity

authors： Rivoire B,Ranchoff BJ,Chatterjee D,Gaylord H,Tsang AY,Kolk AH,Aspinall GO,Brennan PJ

更新日期：1989-10-01 00:00:00

abstract：:The data presented indicate that in experimental Pseudomonas aeruginosa infection of mice, protease enhances the virulence of the organism. Anesthetized CBA/Lü mice were subjected to a 15-s flame burn and infected with a wild-type protease-producing strain and two of its protease-deficient mutants. The average bacteri...

journal_title：Infection and immunity

authors： Pavlovskis OR,Wretlind B

更新日期：1979-04-01 00:00:00

abstract：:Recurrent pulmonary infections with Staphylococcus aureus and Pseudomonas aeruginosa are a major problem in cystic fibrosis (CF), leading to severe and progressive deterioration of the respiratory tract. Fibronectin (FN) has a binding site(s) for S. aureus and Streptococcus pyogenes. This bacterial bindings site(s) wa...

journal_title：Infection and immunity

authors： Stanislawski L,Sorin M

更新日期：1991-03-01 00:00:00

abstract：:This study was undertaken to determine the sequence of events in the microenvironment of the intestinal tract that culminate in the symptoms of cholera and to attempt to define more clearly the mechanisms involved in antibacterial immunity. The extent to which mucus occurs in the normal intestine of rabbits and the ap...

journal_title：Infection and immunity

authors： Schrank GD,Verwey WF

更新日期：1976-01-01 00:00:00

abstract：:Growing Streptococcus gordonii Spp+ phase variants, which have normal levels of glucosyltransferase (GTF) activity, use sucrose to promote their accumulation on surfaces by forming a cohesive bacterium-insoluble glucan polymer mass (BPM). Spp- phase variants, which have lower levels of GTF activity, do not form BPMs a...

journal_title：Infection and immunity

authors： Vickerman MM,Jones GW

更新日期：1992-10-01 00:00:00

abstract：:The innate and the adaptive arms of the mucosal immune system must be coordinated to facilitate the control of pathogenic invasion while maintaining immune homeostasis. Toll-like receptors, able to activate the cell to produce bactericidal and inflammatory cytokines but also able to upregulate antigen (Ag)-presenting ...

journal_title：Infection and immunity

authors： Muthukuru M,Cutler CW

更新日期：2008-02-01 00:00:00

abstract：:We have previously described a new system for the delivery of recombinant antigens in live Salmonella vaccines as genetic fusions to the C terminus of fragment C of tetanus toxin (TetC) driven by the anaerobically inducible nirB promoter. It has been reported that preimmunization with tetanus toxoid (TT) can suppress ...

journal_title：Infection and immunity

authors： Chabalgoity JA,Villareal-Ramos B,Khan CM,Chatfield SN,de Hormaeche RD,Hormaeche CE

更新日期：1995-07-01 00:00:00

abstract：:Cryptococcus neoformans is surrounded by an antiphagocytic polysaccharide capsule whose primary constituent is glucuronoxylomannan (GXM). Three prominent structural features of GXM are single xylosyl and glucuronosyl side chains and O acetylation of the mannose backbone. Isogenic pairs of O-acetyl-positive and O-acety...

journal_title：Infection and immunity

authors： Kozel TR,Levitz SM,Dromer F,Gates MA,Thorkildson P,Janbon G

更新日期：2003-05-01 00:00:00

abstract：:Cell-mediated immunity is critical in host resistance against the pathogenic fungus Histoplasma capsulatum. To explore the role of L3T4+ T cells in protection of mice against H. capsulatum infection, we examined the effect of in vivo treatment with anti-L3T4 monoclonal antibody (MAb) GK1.5 on the course of murine diss...

journal_title：Infection and immunity

authors： Gomez AM,Bullock WE,Taylor CL,Deepe GS Jr

更新日期：1988-07-01 00:00:00

abstract：:A total of 224 strains were serogrouped by coagglutination (COA) and serotyped by protein I enzyme-linked immunosorbent assay (ELISA). Of these strains, 61 were from patients with disseminated gonococcal infection, 21 were from patients with pelvic inflammatory disease, and 115 were from patients with uncomplicated go...

journal_title：Infection and immunity

authors： Sandstrom EG,Knapp JS,Buchanan TB

更新日期：1982-01-01 00:00:00

abstract：:Salmonella strains that lack or overproduce DNA adenine methylase (Dam) elicit a protective immune response to different Salmonella species. To generate vaccines against other bacterial pathogens, the dam genes of Yersinia pseudotuberculosis and Vibrio cholerae were disrupted but found to be essential for viability. O...

journal_title：Infection and immunity

authors： Julio SM,Heithoff DM,Provenzano D,Klose KE,Sinsheimer RL,Low DA,Mahan MJ

更新日期：2001-12-01 00:00:00

abstract：:By screening a genomic lambda library of Streptococcus equi subsp. zooepidemicus, we have cloned and sequenced a gene, termed fnz, encoding a fibronectin (Fn)-binding protein called FNZ. On the basis of the deduced amino acid sequence of FNZ, the mature protein has a molecular mass of approximately 61 kDa. Analysis of...

journal_title：Infection and immunity

authors： Lindmark H,Jacobsson K,Frykberg L,Guss B

更新日期：1996-10-01 00:00:00

abstract：:Inactivation of sortase gene srtA in Streptococcus pneumoniae strain R6 caused the release of beta-galactosidase and neuraminidase A (NanA) from the cell wall into the surrounding medium. Both of these surface proteins contain the LPXTG motif in the C-terminal domain. Complementation with plasmid-borne srtA reversed p...

journal_title：Infection and immunity

authors： Kharat AS,Tomasz A

更新日期：2003-05-01 00:00:00

abstract：:Pertussis toxin (PT), a virulence factor secreted by Bordetella pertussis, contributes to respiratory tract infection and disease caused by this pathogen. By comparing a wild-type (WT) B. pertussis strain to a mutant strain with an in-frame deletion of the ptx genes encoding PT (DeltaPT), we recently found that the la...

journal_title：Infection and immunity

authors： Carbonetti NH,Artamonova GV,Andreasen C,Dudley E,Mays RM,Worthington ZE

更新日期：2004-06-01 00:00:00

abstract：:Salmonella enterica serovar Typhimurium, similar to various facultative intracellular pathogens, has been shown to respond to the hostile conditions inside macrophages of the host organism by inducing stress proteins, such as DnaK. DnaK forms a chaperone machinery with the cochaperones DnaJ and GrpE. To elucidate the ...

journal_title：Infection and immunity

authors： Takaya A,Tomoyasu T,Matsui H,Yamamoto T

更新日期：2004-03-01 00:00:00