Hydrocortisone-induced increase of PDGF beta-receptor expression in a human malignant mesothelioma cell line.

abstract：:Differentiation and apoptosis are precisely regulated events in early embryogenesis. Retinoic acid-induced differentiation in the embryonal carcinoma (EC) cell line NCR-G3 triggers concurrent induction of apoptosis. Using this system, which serves as a model of early embryogenesis, the expression of various bcl-2-rela...

journal_title：Experimental cell research

authors： Sano M,Umezawa A,Abe H,Akatsuka A,Nonaka S,Shimizu H,Fukuma M,Hata J

更新日期：2001-05-15 00:00:00

abstract：:Distal-less homeobox 5 (Dlx5) is a pro-osteogenic but anti-adipogenic transcription factor that regulates lineage commitment in mesenchymal stem cells. Although the expression of Dlx5 is known to be decreased by adipogenic stimuli, the mechanism of Dlx5 down-regulation has not yet been clarified. MicroRNAs (miRNAs) ar...

journal_title：Experimental cell research

authors： Qadir AS,Woo KM,Ryoo HM,Baek JH

更新日期：2013-08-15 00:00:00

abstract：:Osteoporosis due to unloading-induced bone loss is a critical issue in the modern aging society. Although the mechanisms underlying this phenomenon are largely unknown, osteopontin (OPN) is one of the critical mediators required for unloading-induced bone loss [M. Ishijima, S.R. Rittling, T. Yamashita, K. Tsuji, H. Ku...

journal_title：Experimental cell research

authors： Ishijima M,Ezura Y,Tsuji K,Rittling SR,Kurosawa H,Denhardt DT,Emi M,Nifuji A,Noda M

更新日期：2006-10-01 00:00:00

abstract：:Esophageal squamous cell carcinoma (ESCC) is one of the most malignant tumors in China with a poor prognosis. Most ESCC patients were diagnosed at advanced stages, losing the opportunity for surgical excision. Hence, it remains a pressing work to identify biomarkers for early detection, prognosis prediction and target...

journal_title：Experimental cell research

authors： Yuan H,Zhou W,Yang Y,Xue L,Liu L,Song Y

更新日期：2018-06-01 00:00:00

abstract：:Two HL60 clones (C12 and C13) totally insensitive to differentiation induction by dimethylsulfoxide (Me2SO) are described. They have been growing continuously in the presence of the inducer for more than 6 months. The morphological and cytochemical features of the two populations are quite similar to those of the orig...

journal_title：Experimental cell research

authors： Ferrero D,Gallo E,Lanfrancone L,Tarella C

更新日期：1983-08-01 00:00:00

abstract：:In order to explore the potential value of Chinese hamster ovary (CHO) cells for the isolation of peroxisomal mutants defective in the peroxisomal fatty acid oxidation system, some characteristics of their peroxisomes were studied. Catalase was detected biochemically and histochemically in peroxisome-like particles in...

journal_title：Experimental cell research

authors： Santos MJ,Garrido J,Oliver C,Robbins AR,Leighton F

更新日期：1985-11-01 00:00:00

abstract：:Drosophila sHSPs (small heat shock proteins) are expressed in the absence of stress in specific regions of the central nervous system and in gonads of young adults flies. In these two organs, the sHSPs show a cell-specific and developmental stage-specific pattern of expression suggesting distinct regulation and functi...

journal_title：Experimental cell research

authors： Marin R,Landry J,Tanguay RM

更新日期：1996-02-25 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are non-immunogenic, multipotent cells with at least trilineage differentiation potential. They promote wound healing, improve regeneration of injured tissue, and mediate numerous other health effects. MSCs migrate to sites of injury and stimulate repair either through direct differentiat...

journal_title：Experimental cell research

authors： Naaldijk Y,Johnson AA,Ishak S,Meisel HJ,Hohaus C,Stolzing A

更新日期：2015-10-15 00:00:00

abstract：:Proteolysis of corneodesmosin, a 52- to 56-kDa basic protein located in the extracellular part of the modified desmosomes (corneodesmosomes) of human cornified epithelia, is thought to be a key event of desquamation. Three monoclonal antibodies specific for human corneodesmosin were used to search for the expression o...

journal_title：Experimental cell research

authors： Montézin M,Simon M,Guerrin M,Serre G

更新日期：1997-02-25 00:00:00

abstract：:Nucleoporins (Nups) are a large and diverse family of proteins that mediate nucleocytoplasmic transport at interphase of vertebrate cells. Nups also function in mitosis progression. However, whether Nups are involved in oocyte meiosis progression is still rarely known. In this study, we delineated the roles and regula...

journal_title：Experimental cell research

authors： Chen F,Jiao XF,Zhang JY,Wu D,Ding ZM,Wang YS,Miao YL,Huo LJ

更新日期：2018-10-15 00:00:00

abstract：:Prenucleolar bodies (PNBs) are transitory structures which serve as building blocks for nucleoli at the transition mitosis/interphase. The assembly of PNBs and their pathway are not clearly understood. To better understand these events, the behavior of the PNB-containing PM-Scl 100 protein was compared with that of ot...

journal_title：Experimental cell research

authors： Fomproix N,Hernandez-Verdun D

更新日期：1999-09-15 00:00:00

abstract：:Invasion processes underlie or accompany several pathological processes but only a limited number of high-throughput capable phenotypic models exist to test anti-invasive compounds in vitro. We here evaluated 3D co-cultures as a high-content phenotypic screening system for fibrotic invasive processes. 3D multicellular...

journal_title：Experimental cell research

authors： Wenzel C,Otto S,Prechtl S,Parczyk K,Steigemann P

更新日期：2015-11-15 00:00:00

abstract：:Cytoplasts derived from senescent and quiescent human diploid cells inhibit DNA synthesis initiation when fused with cells capable of proliferation. When the cytoplasts were subjected to a variety of conditions (trypsin and cycloheximide treatment and growth on fibronectin), this inhibitory activity was lost, suggesti...

journal_title：Experimental cell research

authors： Pereira-Smith OM,Fisher SF,Smith JR

更新日期：1985-10-01 00:00:00

abstract：:TGFβ contributes to mesangial cell hypertrophy and matrix protein increase in various kidney diseases including diabetic nephropathy. Deptor is an mTOR-interacting protein and suppresses mTORC1 and mTORC2 activities. We have recently shown that TGFβ-induced inhibition of deptor increases the mTOR activity. The mechani...

journal_title：Experimental cell research

authors： Maity S,Bera A,Ghosh-Choudhury N,Das F,Kasinath BS,Choudhury GG

更新日期：2018-03-01 00:00:00

abstract：:Megakaryocytes (Mks) are unique cells in the human body in that they carry a single and polyploid nucleus. It is therefore of interest to understand their nuclear ultrastructure. PML oncogenic domains (PODs) were described in several types of eukaryotic cells using human autoantibodies which recognize nuclear antigens...

journal_title：Experimental cell research

authors： Drouin A,Schmitt A,Massé JM,Cieutat AM,Fichelson S,Cramer EM

更新日期：2001-12-10 00:00:00

abstract：:Hispidin, a phenolic compound from Phellinus linteus (a medicinal mushroom), has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties. However, the cardioprotective efficacy of hispidin has not yet been investigated. In the present study, we investigated the protective ef...

journal_title：Experimental cell research

authors： Kim DE,Kim B,Shin HS,Kwon HJ,Park ES

更新日期：2014-10-01 00:00:00

abstract：:NRK rat cells infected with a transformation-defective, temperature-sensitive (ts) mutant of the avian sarcoma virus could not proliferate in Ca2+-deficient medium at a nonpermissive temperature (40 degrees C) that inactivated the viral pp60v-src-transforming product and rendered the cells phenotypically untransformed...

journal_title：Experimental cell research

authors： Durkin JP,Whitfield JF

更新日期：1985-04-01 00:00:00

abstract：:Progressive pathophysiologic modifications of endothelial cells are associated with aging. In vitro, endothelial cell senescence is accompanied by the failure to proliferate as well as by perturbations in gene expression. Here we show that (i) senescence enhances monoblastoid U937 cell adhesion to the endothelial mono...

journal_title：Experimental cell research

authors： Maier JA,Statuto M,Ragnotti G

更新日期：1993-09-01 00:00:00

abstract：:The human neuroblastoma cell line SK-N-BE can be induced to differentiate by retinoic acid (RA) or by alpha-difluoromethylornithine (DFMO). The former inducer produces neurite outgrowth, 60% reduction of growth rate, overexpression of neural antigens, and enhanced gamma-aminobutyric acid (GABA) and acetylcholinesteras...

journal_title：Experimental cell research

authors： Melino G,Farrace MG,Ceru' MP,Piacentini M

更新日期：1988-12-01 00:00:00

abstract：OBJECTIVE:To investigate whether transmyocardial drilling revascularization combined with heparinized basic fibroblast growth factor (bFGF)-incorporating degradable stent implantation (TMDRSI) can promote myocardial regeneration after acute myocardial infarction (AMI). METHODS:A model of AMI was generated by ligating ...

journal_title：Experimental cell research

authors： Zhang GW,Wen T,Gu TX,Li-Ling J,Wang C,Zhao Y,Liu J,Wang Y,Liu TJ,Lü F

更新日期：2012-02-15 00:00:00

abstract：:Tumor cell adhesion within host organ microvasculature, its stabilization and invasion into host organ parenchyma appear to be important steps during formation of distant metastasis. These interactions of circulating tumor cells with the host organs occur in the presence of fluid shear forces and soluble and cellular ...

journal_title：Experimental cell research

authors： Korb T,Schlüter K,Enns A,Spiegel HU,Senninger N,Nicolson GL,Haier J

更新日期：2004-09-10 00:00:00

abstract：:Myosin phosphatase target subunit 1 (MYPT1), together with catalytic subunit of type1 delta isoform (PP1cdelta) and a small 20-kDa regulatory unit (M20), form a heterotrimeric holoenzyme, myosin phosphatase (MP), which is responsible for regulating the extent of myosin light chain phosphorylation. Here we report the i...

journal_title：Experimental cell research

authors： Twomey E,Li Y,Lei J,Sodja C,Ribecco-Lutkiewicz M,Smith B,Fang H,Bani-Yaghoub M,McKinnell I,Sikorska M

更新日期：2010-01-01 00:00:00

abstract：:Phosphorylation of types III and IV intermediate filaments (IFs) is known to regulate their organization and function. Phosphorylation of the amino-terminal head domain sites on types III and IV IF proteins plays a key role in the assembly/disassembly of IF subunits into 10 nm filaments, and influences the phosphoryla...

journal_title：Experimental cell research

authors： Sihag RK,Inagaki M,Yamaguchi T,Shea TB,Pant HC

更新日期：2007-06-10 00:00:00

abstract：:Thyroid hormone (T3) and estradiol (Est) modulate biological processes by binding to nuclear receptor proteins that, through interactions with specific response elements in the regulatory regions of genes, modulate gene transcription. Est stimulation of estrogen receptor (ER)-positive breast carcinoma cell growth occu...

journal_title：Experimental cell research

authors： Shao ZM,Sheikh MS,Rishi AK,Dawson MI,Li XS,Wilber JF,Feng P,Fontana JA

更新日期：1995-05-01 00:00:00

abstract：:Autophagy is a major catabolic process allowing the renewal of intracellular organelles by which cells maintain their homeostasis. We have previously shown that autophagy is controlled by two transduction pathways mediated by a heterotrimeric Gi3 protein and phosphatidylinositol 3-kinase activities in the human colon ...

journal_title：Experimental cell research

authors： Bauvy C,Gane P,Arico S,Codogno P,Ogier-Denis E

更新日期：2001-08-15 00:00:00

abstract：:Autophagy has been shown to be critically associated with the central mechanisms underlying Parkinson's disease (PD), while the mechanisms contributing to the imbalance of autophagy remain unclear. Small nucleolar RNA host gene 1 (SNHG1), a well-studied long noncoding RNA, has been reported to be significantly increas...

journal_title：Experimental cell research

authors： Qian C,Ye Y,Mao H,Yao L,Sun X,Wang B,Zhang H,Xie L,Zhang H,Zhang Y,Zhang S,He X

更新日期：2019-11-01 00:00:00

abstract：:The replication kinetics and cytological changes of normal human oral keratinocytes (NHOK) isolated from the basal surface of oral epithelial sheet and cultured as dispersed cells in low (0.15 mM) Ca(2+) medium without serum were analyzed. Replicating NHOK were quantitated by cell count and identified by [(3)H]thymidi...

journal_title：Experimental cell research

authors： Kang MK,Bibb C,Baluda MA,Rey O,Park NH

更新日期：2000-08-01 00:00:00

abstract：:Accumulating evidence indicates that elevated S100P promotes the pathogenesis of cancers, including colon cancer. S100P exerts its effects by binding to and activating the Receptor for Advance Glycation End-products (RAGE). The effects of up-regulated S100P/RAGE signaling on cell functions are well documented. Despite...

journal_title：Experimental cell research

authors： Onyeagucha BC,Mercado-Pimentel ME,Hutchison J,Flemington EK,Nelson MA

更新日期：2013-08-01 00:00:00

abstract：:The precise distribution of DNA within the resting human T lymphocyte nucleolus has been investigated, at the ultrastructural level, by cytochemical and molecular immunocytochemical techniques. The nucleolus is partially enveloped by a layer of condensed chromatin which, at several places, penetrates into the nucleola...

journal_title：Experimental cell research

authors： Vandelaer M,Thiry M,Goessens G

更新日期：1993-04-01 00:00:00

abstract：:Lamin A is a component of the nuclear envelope that is synthesized as a precursor prelamin A molecule and then processed into mature lamin A through sequential steps of posttranslational modifications and proteolytic cleavages. Remarkably, over 400 distinct point mutations have been so far identified throughout the LM...

journal_title：Experimental cell research

authors： Reddy S,Comai L

更新日期：2012-01-01 00:00:00