Free radical scavenging activity of the alcoholic extract of Trewia polycarpa roots in arthritic rats.

Abstract:

:The alcoholic extract of Trewia polycarpa roots (TPE), which exhibited significant anti-inflammatory activity, was evaluated for the possible mode of action by studying its antioxidant potential in adjuvant-induced arthritic rats. The biological defence system constituting the superoxide dismutase, glutathione peroxidase, ascorbic acid showed a significant increase while the lipid peroxide content was found to decrease to a large extent on TPE treatment thereby indicating the extracts free radical scavenging property. Histopathological studies too supported anti-arthritic potential of the roots of Trewia polycarpa.

journal_name

J Ethnopharmacol

authors

Chamundeeswari D,Vasantha J,Gopalakrishnan S,Sukumar E

doi

10.1016/s0378-8741(03)00143-0

keywords:

subject

Has Abstract

pub_date

2003-09-01 00:00:00

pages

51-6

issue

1

eissn

0378-8741

issn

1872-7573

pii

S0378874103001430

journal_volume

88

pub_type

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