Abstract:
:A cell-free system derived from Dictyostelium discoideum has been used to study the kinetics of inhibition of RNase P by puromycin, amicetin and blasticidin S. Detailed kinetic analysis showed that the type of inhibition of RNase P activity by puromycin is simple competitive, whereas the type of inhibition by amicetin and blasticidin S is simple non-competitive. On the basis of Ki values amicetin is stronger inhibitor than puromycin and blasticidin S.
journal_name
Mol Biol Repjournal_title
Molecular biology reportsauthors
Kalavrizioti D,Vourekas A,Tekos A,Tsagla A,Stathopoulos C,Drainas Ddoi
10.1023/a:1022290110116keywords:
subject
Has Abstractpub_date
2003-03-01 00:00:00pages
9-14issue
1eissn
0301-4851issn
1573-4978journal_volume
30pub_type
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