Activity of HDV ribozymes to trans-cleave HCV RNA.

abstract：AIM:To study the expression of a disintegrin and metalloproteinase 17 (ADAM17) mRNA in hepatocellular carcinoma (HCC) and to evaluate the relationship between ADAM17 mRNA expression and clinicopathological features of HCC. METHODS:Hepatocellular carcinomas (HCC) from 31 cases were divided into small HCC (SHCC), nodula...

journal_title：World journal of gastroenterology

authors： Ding X,Yang LY,Huang GW,Wang W,Lu WQ

更新日期：2004-09-15 00:00:00

abstract：:A 57-year-old man consulted a local hospital because of a persistent slight fever. At the age of 37 years he was diagnosed having B-type hepatitis, but left the liver dysfunction untreated. Twenty years later, he was diagnosed having chronic hepatitis B, hepatocellular carcinoma (HCC) and macrocytic anemia, and referr...

journal_title：World journal of gastroenterology

authors： Okada T,Kubota K,Kita J,Kato M,Sawada T

更新日期：2007-08-28 00:00:00

abstract：AIM:To elucidate the effect of p27(KIP1) on cell cycle and apoptosis regulation in gastric carcinoma cells. METHODS:The whole length of p27(KIP1) cDNA was transfected into human gastric cancer cell line SCG7901 by lipofectamine. Expression of p27(KIP1) protein or mRNA was analyzed by Western blot and RNA dot blotting,...

journal_title：World journal of gastroenterology

authors： Zheng JY,Wang WZ,Li KZ,Guan WX,Yan W

更新日期：2005-12-07 00:00:00

abstract：AIM:To investigate the association of serum gamma-glutamyl transferase (GGT) levels with chronic hepatitis B infection and hepatitis B e antigen (HBeAg) seroconversion. METHODS:A retrospective study was performed on clinical data collected from patients who had been positive for hepatitis B surface antigen for > 6 mo ...

journal_title：World journal of gastroenterology

authors： Huang R,Yang CC,Liu Y,Xia J,Su R,Xiong YL,Wang GY,Sun ZH,Yan XM,Lu S,Wu C

更新日期：2015-09-14 00:00:00

abstract：:Data from genome wide association studies and geoepidemiological studies established that a combination of genetic predisposition and environmental stimulation is required for the loss of tolerance in primary biliary cholangitis (PBC). The serologic hallmark of PBC are the presence of high titer anti-mitochondrial aut...

journal_title：World journal of gastroenterology

authors： Wang J,Yang G,Dubrovsky AM,Choi J,Leung PS

更新日期：2016-01-07 00:00:00

abstract：AIM:To study the predictive value of the vegetative-depressive symptoms of the Zung Depression Rating Scale for the occurrence of depression during treatment with peg-interferon alpha-2b of chronic hepatitis C (CHC) patients. METHODS:The predictive value of vegetative-depressive symptoms at 4 wk of treatment for the o...

journal_title：World journal of gastroenterology

authors： Robaeys G,De Bie J,Wichers MC,Bruckers L,Nevens F,Michielsen P,Van Ranst M,Buntinx F

更新日期：2007-11-21 00:00:00

abstract：:The use of thiopurines as immunosuppression for the treatment of refractory or chronic active inflammatory bowel disease is established for both Crohn's disease and ulcerative colitis. Nevertheless, many questions remain concerning the optimal treatment regimens of azathioprine, 6-mercaptopurine and thioguanine. We wi...

journal_title：World journal of gastroenterology

authors： Frei P,Biedermann L,Nielsen OH,Rogler G

更新日期：2013-02-21 00:00:00

abstract：AIM:Granuloma is considered the hallmark of microscopic diagnosis in Crohn's disease (CD), but granulomas can be detected in only 21-60% of CD patients. The aim of this study was to evaluate the frequency of granulomas by multiple endoscopic biopsies in patients with CD and to examine whether group of patients with or ...

journal_title：World journal of gastroenterology

authors： Molnár T,Tiszlavicz L,Gyulai C,Nagy F,Lonovics J

更新日期：2005-05-28 00:00:00

abstract：:A primary clear cell adenocarcinoma of the colon is a rare oncologic entity. We herein report a case of such a tumor of the sigmoid colon in a 71-year-old woman who was successfully treated by an endoscopic polypectomy in our hospital. We also reviewed the published reports regarding cases of primary clear cell tumors...

journal_title：World journal of gastroenterology

authors： Soga K,Konishi H,Tatsumi N,Konishi C,Nakano K,Wakabayashi N,Mitsufuji S,Kataoka K,Okanoue T,Mukaisho K,Hattori T

更新日期：2008-02-21 00:00:00

abstract：:Although gastric cancer (GC) is one of the leading causes of cancer-related death, major therapeutic advances have not been made, and patients with GC still face poor outcomes. The prognosis of GC also remains poor because the molecular mechanisms of GC progression are incompletely understood. MicroRNAs (miRNAs) are n...

journal_title：World journal of gastroenterology

authors： Ishiguro H,Kimura M,Takeyama H

更新日期：2014-05-21 00:00:00

abstract：:AIM:To compare the features of gastroesophageal reflux disease between elderly and younger patients.METHODS:Twenty-four hour pH-monitoring and endoscopy were performed for the 66 elderly patients with typical gastroesophageal reflux symptoms, and the results were compared with 112 symptomatic younger patients.RESULTS:...

journal_title：World journal of gastroenterology

authors： Huang X,Zhu HM,Deng CZ,Porro GB,Sangaletti O,Pace F

更新日期：1999-10-01 00:00:00

abstract：AIM:To investigate the association between TP53 Arg72Pro polymorphism and esophageal cancer (EC) risk using meta-analysis. METHODS:All eligible studies published before March 1, 2010 were selected by searching PubMed using keywords "p53" or "TP53", "polymorphism" or "variation", "esophageal" and "cancer" or "carcinoma...

journal_title：World journal of gastroenterology

authors： Jiang DK,Yao L,Wang WZ,Peng B,Ren WH,Yang XM,Yu L

更新日期：2011-03-07 00:00:00

abstract：:The management of intraductal papillary mucinous neoplasms (IPMN) is presently evolving as a result of the improved understanding of the natural history and biological behavior of the different pancreatic cystic neoplasms; and better preoperative diagnosis of these neoplasms due to advancement in preoperative diagnost...

journal_title：World journal of gastroenterology

authors： Goh BK

更新日期：2015-09-14 00:00:00

abstract：AIM:To investigate the agreement and prognostic value of different measures of covert hepatic encephalopathy (CHE). METHODS:One-hundred-and-thirty-two cirrhotic outpatients underwent electroencephalography (EEG), paper-and-pencil psychometry (PHES) and critical flicker frequency, scored on the original/modified (CFFo/...

journal_title：World journal of gastroenterology

authors： Montagnese S,Balistreri E,Schiff S,De Rui M,Angeli P,Zanus G,Cillo U,Bombonato G,Bolognesi M,Sacerdoti D,Gatta A,Merkel C,Amodio P

更新日期：2014-11-14 00:00:00

abstract：AIM:To investigate the effect of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expression of epidermal growth factor receptor (EGFR) gene in gastric mucosal cells. METHODS:The stress-induced gastric mucosal injury in rat model was established by water-immersion and restra...

journal_title：World journal of gastroenterology

authors： Yang ZB,Yan J,Zou XP,Yi SX,Chang XR,Lin YP,Li XP

更新日期：2006-09-14 00:00:00

abstract：:Inflammatory bowel diseases (IBD) can be really considered to be systemic diseases since they are often associated with extraintestinal manifestations, complications, and other autoimmune disorders. Indeed, physicians who care for patients with ulcerative colitis and Crohn's disease, the two major forms of IBD, face a...

journal_title：World journal of gastroenterology

authors： Danese S,Semeraro S,Papa A,Roberto I,Scaldaferri F,Fedeli G,Gasbarrini G,Gasbarrini A

更新日期：2005-12-14 00:00:00

abstract：AIM:To evaluate the diagnostic value and safety mainly regarding incidents of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for pancreatic cystic lesions (PCLs). METHODS:A total of 150 consecutive patients with suspected PCLs were prospectively enrolled from April 2015 to November 2016. We finally enro...

journal_title：World journal of gastroenterology

authors： Du C,Chai NL,Linghu EQ,Li HK,Sun YF,Xu W,Wang XD,Tang P,Yang J

更新日期：2017-08-14 00:00:00

abstract：:Small cell neuroendocrine carcinoma of the ampulla of Vater is extremely rare and different from the common ampullary adenocarcinoma. The ampullary adenoma is also a rare neoplasm and has the potential to develop an adenocarcinoma. Their coexistence has been rarely reported in the literature. We herein describe an unu...

journal_title：World journal of gastroenterology

authors： Sun JH,Chao M,Zhang SZ,Zhang GQ,Li B,Wu JJ

更新日期：2008-08-07 00:00:00

abstract：AIM:To elucidate the role of contrast-enhanced endoscopic ultrasonography (CE-EUS) in the diagnosis of branch duct intraductal papillary mucinous neoplasm (BD-IPMN). METHODS:A total of 50 patients diagnosed with BD-IPMN by computed tomography (CT) and endoscopic ultrasonography (EUS) at our institute were included in ...

journal_title：World journal of gastroenterology

authors： Harima H,Kaino S,Shinoda S,Kawano M,Suenaga S,Sakaida I

更新日期：2015-05-28 00:00:00

abstract：AIM:To determine risk factors associated with hepatitis C virus (HCV) treatment failure after direct acting antivirals in patients with complex treatment histories. METHODS:All HCV mono-infected patients who received treatment at our institution were queried. Analysis was restricted to patients who previously failed t...

journal_title：World journal of gastroenterology

authors： Hartman J,Bichoupan K,Patel N,Chekuri S,Harty A,Dieterich D,Perumalswami P,Branch AD

更新日期：2015-11-21 00:00:00

abstract：AIM:To measure the normal space between the posterior wall of the vagina and the anterior wall of the respectively rectum using computed tomography (CT) and reveal its were relationship to rectocele. METHODS:A total of twenty female volunteers without rectocele were examined by CT scan. We performed a middle level con...

journal_title：World journal of gastroenterology

authors： Liu J,Zhai LD,Li YS,Liu WX,Wang RH

更新日期：2009-06-28 00:00:00

abstract：AIM:To investigate the protective effect and mechanism of rebamipide on small intestinal permeability induced by diclofenac in mice. METHODS:Diclofenac (2.5 mg/kg) was administered once daily for 3 d orally. A control group received the vehicle by gavage. Rebamipide (100 mg/kg, 200 mg/kg, 400 mg/kg) was administered i...

journal_title：World journal of gastroenterology

authors： Diao L,Mei Q,Xu JM,Liu XC,Hu J,Jin J,Yao Q,Chen ML

更新日期：2012-03-14 00:00:00

abstract：:Thiopurine analogs and anti-tumor necrosis factor (TNF) agents have dramatically changed the therapeutics of inflammatory bowel diseases (IBD), improving short and long-term outcomes. Unfortunately some patients do not respond to therapy and others lose response over time. The pharmacokinetic properties of these drugs...

journal_title：World journal of gastroenterology

authors： Yarur AJ,Abreu MT,Deshpande AR,Kerman DH,Sussman DA

更新日期：2014-04-07 00:00:00

abstract：AIM:To study the effect of aprotinin used in orthotopic liver transplantation (OLT) on the intraoperative requirement for blood products and on the incidence of laparotomy for bleeding, thrombotic events and mortality. METHODS:A systematic review of the literature in the electronic database Medline and the Clinic Tria...

journal_title：World journal of gastroenterology

authors： Liu CM,Chen J,Wang XH

更新日期：2008-03-07 00:00:00

abstract：:Neuroendocrine carcinoma (NEC) of the gallbladder is a rare subtype of gallbladder tumor. Here, we report two cases of NEC in two patients initially suspected to have gallbladder carcinoma. No specific symptoms or abnormal blood test results were observed preoperatively. Abdominal computed tomography scans indicated i...

journal_title：World journal of gastroenterology

authors： Chen H,Shen YY,Ni XZ

更新日期：2014-09-07 00:00:00

abstract：:Primary biliary cirrhosis (PBC) is an autoimmune disease of the liver characterized by progressive bile duct destruction eventually leading to cirrhosis and liver failure. The serological hallmark of the disease is the presence of circulating antimitochondrial antibodies (AMA). These reflect the presence of autoreacti...

journal_title：World journal of gastroenterology

authors： Lleo A,Invernizzi P,Mackay IR,Prince H,Zhong RQ,Gershwin ME

更新日期：2008-06-07 00:00:00

abstract：AIM:To observe expression of CD14 protein and CD14 gene in rat liver sinusoidal endothelial cells (LSECs) during endotoxemia, and the role of CD14 protein in the activation of lipopolysaccharide (LPS)-induced LSECs. METHODS:Wistar rat endotoxemia model was established first by injection of a dose of LPS (5mg/kg, Esche...

journal_title：World journal of gastroenterology

authors： Gong JP,Dai LL,Liu CA,Wu CX,Shi YJ,Li SW,Li XH

更新日期：2002-06-01 00:00:00

abstract：AIM:Trace elements (TE) metabolism is altered in inflammatory bowel diseases. TE (zinc and copper) are constituents of antioxidant enzymes. Iron is involved in the pathogenesis of chronic inflammation. The aim was to evaluate zinc and copper status and the effects of iron manipulation in experimental colitis. METHODS:...

journal_title：World journal of gastroenterology

authors： Barollo M,D'Inca R,Scarpa M,Medici V,Cardin R,Bortolami M,Ruffolo C,Angriman I,Sturniolo GC

更新日期：2005-07-28 00:00:00

abstract：AIM:To assess the diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index (APRI), and liver stiffness measurement (LSM) in patients with hepatitis B virus infection who have persistently normal alanine transaminase (PNALT). METHODS:We enrolled 245 patients with chronic hepatitis B: 95 in PNALT gr...

journal_title：World journal of gastroenterology

authors： Tan YW,Zhou XB,Ye Y,He C,Ge GH

更新日期：2017-08-21 00:00:00

abstract：AIM:To explore hemodynamics and vasoactive substance levels during renal vein congestion that occurs in the anhepatic phase of liver transplantation. METHODS:New Zealand rabbits received ligation of the hepatic pedicle, supra-hepatic vena cava and infra-hepatic vena cava [anhepatic phase group (APH); n = 8], the renal...

journal_title：World journal of gastroenterology

authors： Li ZX,Wang MC,Zhang YC,Mao J,Chen M,Ni R,Wei FX,Wang GN,Zhang LY

更新日期：2015-05-14 00:00:00