Abstract:
:Recent data from lesion and brain imaging studies have questioned the well-established assumption of a close functional-anatomic link between syntax and Broca's area and semantics and Wernicke's area. In the present study we used functional magnetic resonance imaging (fMRI) to investigate the neuroanatomical correlates of semantic and syntactic functions and possible interdependencies between the related brain systems. In a completely crossed design we varied syntactic processing demands (easy vs difficult to process word order sequences) and the meaningfulness of sentences (real- vs pseudo-word sentences). In comparison to a backward speech condition we found an activation of the left perisylvian region, including the left inferior frontal cortex and the left superior and middle temporal gyri. Semantic in contrast to pseudo-word sentences elicited a stronger activation in both the anterior and the posterior perisylvian cortex. Syntactic difficulty had its strongest effect within the left inferior frontal region and this effect was more pronounced for semantic than nonsemantic speech. These results suggest that semantic and syntactic language functions are mediated by partly specialized brain systems but that there nevertheless exists a substantial functional overlap of the involved brain structures.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Röder B,Stock O,Neville H,Bien S,Rösler Fdoi
10.1006/nimg.2001.1026keywords:
subject
Has Abstractpub_date
2002-04-01 00:00:00pages
1003-14issue
4eissn
1053-8119issn
1095-9572pii
S1053811901910262journal_volume
15pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract::The suggested revision of the NINCDS-ADRDA criterion for the diagnosis of Alzheimer's disease (AD) includes at least one abnormal biomarker among magnetic resonance imaging (MRI), positron emission tomography (PET) and cerebrospinal fluid (CSF). We aimed to investigate if the combination of baseline MRI and CSF could ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.04.056
更新日期:2012-08-01 00:00:00
abstract::The large amount of imaging data collected in several ongoing multi-center studies requires automated methods to delineate brain structures of interest. We have previously reported on using artificial neural networks (ANN) to define subcortical brain structures. Here we present several automated segmentation methods u...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.05.063
更新日期:2008-01-01 00:00:00
abstract::We established a strategy to perform cross-validation of serial optical coherence scanner imaging (SOCS) and diffusion tensor imaging (DTI) on a postmortem human medulla. Following DTI, the sample was serially scanned by SOCS, which integrates a vibratome slicer and a multi-contrast optical coherence tomography rig fo...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.06.032
更新日期:2014-10-15 00:00:00
abstract::Nonrigid registration and atlas-based parcellation methods were used to compare the volume of the ventricular system and the cross-sectional area of the midsagittal corpus callosum on brain MRIs from 272 subjects in four groups: patients with HIV infection, with and without alcoholism comorbidity, alcoholics, and cont...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.05.052
更新日期:2006-10-15 00:00:00
abstract::Repetition has been shown to activate the so-called 'dorsal stream', a network of temporo-parieto-frontal areas subserving the mapping of acoustic speech input onto articulatory-motor representations. Among these areas, a region in the posterior Sylvian fissure at the temporo-parietal boundary (also called 'area Spt')...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.07.025
更新日期:2012-01-02 00:00:00
abstract::An essential task of our perceptual systems is to bind together the distinctive features of single objects and events into unitary percepts, even when those features are registered in different sensory modalities. In cases where auditory and visual inputs are spatially incongruent, they may still be perceived as belon...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.04.077
更新日期:2014-09-01 00:00:00
abstract::Depression is the most frequent psychiatric disorder in Parkinson's disease (PD). Although evidence suggests that depression in PD is related to the degenerative process that underlies the disease, further studies are necessary to better understand the neural basis of depression in this population of patients. In orde...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.04.059
更新日期:2009-08-15 00:00:00
abstract::Throughout infancy, childhood, and adolescence, our brains undergo remarkable changes. Processes including myelination and synaptogenesis occur rapidly across the first 2-3 years of life, and ongoing brain remodeling continues into young adulthood. Studies have sought to characterize the patterns of structural brain d...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2017.12.097
更新日期:2018-11-15 00:00:00
abstract::Proton magnetic resonance spectroscopy (1H-MRS) has provided valuable information about the neurochemical profile of Alzheimer's disease (AD). However, its clinical utility has been limited in part by the lack of consistent information on how metabolite concentrations vary in the normal aging brain and in carriers of ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2017.03.031
更新日期:2017-05-15 00:00:00
abstract::Growing neurophysiological evidence points to a role of alpha oscillations in divergent thinking (DT). In particular, studies have shown a consistent EEG alpha synchronization during performance on the Alternative Uses Task (AUT), a well-established DT task. However, there is a need for investigating the brain dynamic...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2019.116385
更新日期:2020-02-15 00:00:00
abstract::We have recently performed simultaneous intracranial EEG and fMRI recordings (icEEG-fMRI) in patients with epilepsy. In this technical note, we examine limited thermometric data for potential electrode heating during our protocol and found that heating was ≤0.1 °C in-vitro at least 10 fold less than in-vivo limits. We...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.05.056
更新日期:2012-10-15 00:00:00
abstract::Neuroimaging studies suggest that categorical perception of speech phonemes in adults is primarily subserved by a pathway from bilateral primary auditory areas to association areas in the left middle superior temporal cortex, but the neural substrates underlying categorical speech perception in children are not yet kn...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.11.055
更新日期:2014-04-01 00:00:00
abstract::The ability to mentally imagine the performance of automatic movements has been well-established being employed in sports and physiotherapy as a tool for motor learning and rehabilitation. This is probably mediated by engagement of the same brain areas as during real motor performance. Here we investigated the effect ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.10.073
更新日期:2013-02-01 00:00:00
abstract::The serotonin transporter (SERT) modulates the entire serotonergic system in the brain and influences both the dopaminergic and norepinephrinergic systems. These three systems are intimately involved in normal physiological functioning of the brain and implicated in numerous pathological conditions. Here we use high-r...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.03.026
更新日期:2009-07-15 00:00:00
abstract::Despite considerable interest in enhancing, preserving, and rehabilitating working memory (WM), efforts to elicit sustained behavioral improvements have been met with limited success. Here, we paired WM training with transcranial direct current stimulation (tDCS) to the frontoparietal network over four days. Active tD...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.116615
更新日期:2020-05-01 00:00:00
abstract::Empathy may allow interindividual sharing not only of emotions (e.g., joy, sadness, disgust) but also of sensations (e.g., touch, itching, pain). Although empathy for pain may rely upon both sensory and affective components of the pain experience, neuroimaging studies indicate that only the affective component of the ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.03.010
更新日期:2006-08-01 00:00:00
abstract::The James-Lange theory of emotion proposes that automatically generated bodily reactions not only color subjective emotional experience of stimuli, but also necessitate a mechanism by which these bodily reactions are differentially generated to reflect stimulus quality. To examine this putative mechanism, we simultane...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.neuroimage.2004.10.013
更新日期:2005-02-01 00:00:00
abstract::Temporal connectives (before/after) give us the freedom to describe a sequence of events in different orders. Studies have suggested that 'before-initiating' sentences, in which events are expressed in an order inconsistent with their actual order of occurrence, might need additional computation(s) during comprehensio...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.11.039
更新日期:2012-02-15 00:00:00
abstract::Grey matter (GM) maturation has not been previously studied in healthy preterm children. The purpose of this study was to evaluate the age dependency of GM development in 116 GM areas in preterm subjects. Sixty one preterm infants (corrected age: 13.7+/-9.92 months, gestational age: 33.4+/-1.9 weeks) with normal struc...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.03.072
更新日期:2009-10-01 00:00:00
abstract::Correction for multiple comparisons in neuroimaging data is an important area of research. Recently, wavelet-based methods have gained popularity and have been reported to achieve better sensitivity compared to spatial domain methods. However, these techniques produce smoothed statistical maps which are difficult to i...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1016/j.neuroimage.2006.06.033
更新日期:2006-10-15 00:00:00
abstract::Activity of the prefrontal cortex (PFC) has been observed in previous block-design brain imaging studies of self-initiated movements. However, the meaning of these activations remained unclear. A functional MRI experiment was carried out, which utilized an epoch and an event-related analysis approach to the data. We h...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2005.06.044
更新日期:2005-11-15 00:00:00
abstract::The neural bases of the different processes involved in task switching remain poorly identified. Whether distinct brain regions are involved according to the overall structure of the task sequence and the predictability of task timing during task switching is unknown. To address this question, we used functional magne...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2002.1169
更新日期:2002-09-01 00:00:00
abstract::In this study, we examined the impact of goal-directed processing on the response to emotional pictures and the impact of emotional pictures on goal-directed processing. Subjects (N=22) viewed neutral or emotional pictures in the presence or absence of a demanding cognitive task. Goal-directed processing disrupted the...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.11.048
更新日期:2007-03-01 00:00:00
abstract::EEG mu rhythms (8-13 Hz) recorded at fronto-central electrodes are generally considered as markers of motor cortical activity in humans, because they are modulated when participants perform an action, when they observe another's action or even when they imagine performing an action. In this study, we analyzed the time...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.01.018
更新日期:2015-04-01 00:00:00
abstract::In humans and monkeys the mirror neuron system transforms seen actions into our inner representation of these actions. Here we asked if this system responds also if we see an industrial robot perform similar actions. We localised the motor areas involved in the execution of hand actions, presented the same subjects bl...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.02.003
更新日期:2007-05-01 00:00:00
abstract::The dopaminergic system plays a key role in attention-deficit/hyperactivity disorder (ADHD). Methylphenidate (MP), a dopamine (DA) reuptake inhibitor, is a drug of first choice for treating ADHD. This cross-over study investigated alterations in DA metabolism in young males with ADHD who had never been pharmacological...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.02.025
更新日期:2008-07-01 00:00:00
abstract::Functional imaging studies consistently support the role of the medial prefrontal cortex to be a part of a functional network of reflective self-awareness. The current study introduces a new linguistic task which (1) directly compares self-reference and other-reference, and (2) separates pre-reflective from reflective...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.01.060
更新日期:2008-08-01 00:00:00
abstract::Embodiment theory predicts that mental imagery of object words recruits neural circuits involved in object perception. The degree of visual imagery present in routine thought and how it is encoded in the brain is largely unknown. We test whether fMRI activity patterns elicited by participants reading objects' names in...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.06.093
更新日期:2015-10-15 00:00:00
abstract::The abilities to monitor performance outcomes and, when appropriate, impose strategic adjustments in behavior, are core features of the intact human cognitive control system. Errors committed in choice reaction time tasks are typically followed by two scalp potentials, the error negativity (Ne) and error positivity (P...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.04.028
更新日期:2014-08-15 00:00:00
abstract::Deep brain stimulation (DBS) of the subgenual cingulate gyrus (area CG25) is beneficial in treatment resistant depression. Though the mechanisms of action of Cg25 DBS remain largely unknown, it is commonly believed that Cg25 DBS modulates limbic activity of large networks to achieve thymic regulation of patients. To i...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.10.018
更新日期:2017-02-01 00:00:00