Abstract：
:Despite considerable interest in enhancing, preserving, and rehabilitating working memory (WM), efforts to elicit sustained behavioral improvements have been met with limited success. Here, we paired WM training with transcranial direct current stimulation (tDCS) to the frontoparietal network over four days. Active tDCS enhanced WM performance by modulating interactions between frontoparietal theta oscillations and gamma activity, as measured by pre- and post-training high-density electroencephalography (EEG). Increased phase-amplitude coupling (PAC) between the prefrontal stimulation site and temporo-parietal gamma activity explained behavioral improvements, and was most effective when gamma occurred near the prefrontal theta peak. These results demonstrate for the first time that tDCS-linked WM training elicits lasting changes in behavior by optimizing the oscillatory substrates of prefrontal control.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Jones KT,Johnson EL,Berryhill MEdoi
10.1016/j.neuroimage.2020.116615subject
Has Abstractpub_date
2020-05-01 00:00:00pages
116615eissn
1053-8119issn
1095-9572pii
S1053-8119(20)30102-6journal_volume
211pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract：:Human brain imaging studies have suggested that posterior temporo-parietal regions are involved in auditory spatial processing. We used electroencephalography to investigate the dynamics of temporo-parietal networks during working memory for moving sounds. A delayed matching-to-sample task required a decision on the i...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/s1053-8119(03)00233-7
更新日期：2003-08-01 00:00:00
abstract：:Adolescence is a complex period of concurrent mental and physical development that facilitates adult functioning at multiple levels. Despite the growing number of neuroimaging studies of cognitive development in adolescence focusing on regional activation patterns, there remains a paucity of information about the func...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2018.04.013
更新日期：2018-07-15 00:00:00
abstract：:Recent models of visual recognition have suggested that perceptual analysis may start with a parallel extraction of different spatial frequencies (SF), using a preferential coarse-to-fine (low-to-high SF) sequence of processing. A rapid extraction of low spatial frequency (LSF) information may thus provide an initial ...
journal_title：NeuroImage
pub_type： 临床试验,杂志文章
doi：10.1016/j.neuroimage.2005.06.006
更新日期：2005-11-01 00:00:00
abstract：:In conjunction with the ISBI 2015 conference, we organized a longitudinal lesion segmentation challenge providing training and test data to registered participants. The training data consisted of five subjects with a mean of 4.4 time-points, and test data of fourteen subjects with a mean of 4.4 time-points. All 82 dat...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2016.12.064
更新日期：2017-03-01 00:00:00
abstract：:Large-scale brain functional networks (measured with functional magnetic resonance imaging, fMRI) are organized into separated but interacting modules, an architecture supporting the integration of distinct dynamical processes. In this work we study how the aforementioned modular architecture changes with the progress...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2012.12.073
更新日期：2013-04-15 00:00:00
abstract：:In fMRI, time courses with similar temporal "activation" patterns may belong to different brain regions (i.e., these regions are functionally connected, coactivated). A group of time courses (TCs) corresponding to a particular type of temporal activation pattern should be maximally self-consistent (homogeneous). We de...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1006/nimg.2000.0729
更新日期：2001-04-01 00:00:00
abstract：INTRODUCTION:The safety of magnetic resonance imaging (MRI) for deep brain stimulation (DBS) patients is of great importance to both movement disorders clinicians and to radiologists. The present study utilized the Deep Brain Stimulation Brain Tissue Network's (DBS-BTN's) clinical and neuropathological database to sear...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2010.09.014
更新日期：2011-01-01 00:00:00
abstract：:Previous PET and fMRI brain imaging studies targeting neural networks processing itch sensation have used histamine as the sole itch inducer. In contrast with histamine, cowhage-induced itch is mediated via proteinase activated receptors PAR2 and is transmitted through a separate spinothalamic pathway, therefore imagi...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2011.10.099
更新日期：2012-02-15 00:00:00
abstract：:Perception of speech at multiple temporal scales is important for the efficient extraction of meaningful phonological elements. Individuals with developmental dyslexia have difficulty in the accurate neural representation of phonological aspects of speech, across languages. Recently, it was proposed that these difficu...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2011.09.075
更新日期：2012-02-01 00:00:00
abstract：:Animal studies suggest that N-methyl-D-aspartate receptor (NMDAR) dependent signalling in limbic and prefrontal regions is critically involved in both cognitive and emotional functions. In humans, ketamine-induced transient, and disorder associated chronic NMDAR hypofunction (i.e. in schizophrenia) has been associated...
journal_title：NeuroImage
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.neuroimage.2017.02.049
更新日期：2017-04-15 00:00:00
abstract：:Unilateral sensory stimulation reliably elicits contralateral somatotopic activation of primary (SI) and secondary (SII) somatosensory cortex. There is an ongoing debate about the occurrence and nature of concomitant ipsilateral SI and SII activation. Here we used functional magnetic resonance imaging (fMRI) in health...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2007.05.038
更新日期：2007-09-01 00:00:00
abstract：:Processing speed is an important construct in understanding cognition. This study was aimed to control task specificity for understanding the neural mechanisms underlying cognitive processing speed. Forty young adult subjects performed attention tasks of two modalities (auditory and visual) and two levels of task rule...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2020.117556
更新日期：2021-02-01 00:00:00
abstract：:The robust characterization of real-time brain activity carries potential for many applications. However, the contamination of measured signals by various instrumental, environmental, and physiological sources of noise introduces a substantial amount of signal variance and, consequently, challenges real-time estimatio...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2018.04.042
更新日期：2018-08-01 00:00:00
abstract：:Past animal and human studies robustly report that the cholinergic system plays an essential role in both top-down and bottom-up attentional control, as well as other aspects of cognition (see Ballinger et al., 2016 for a recent review). However, current understanding of how two major cholinergic pathways in the human...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2017.12.012
更新日期：2019-04-15 00:00:00
abstract：:Neuroimagingstudies with positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) have begun to describe the functional neuroanatomy of emotion. Taken separately, specific studies vary in task dimensions and in type(s) of emotion studied and are limited by statistical power and sensitivity. ...
journal_title：NeuroImage
pub_type： 杂志文章,meta分析
doi：10.1006/nimg.2002.1087
更新日期：2002-06-01 00:00:00
abstract：:Instantaneous phase of brain oscillations in electroencephalography (EEG) is a measure of brain state that is relevant to neuronal processing and modulates evoked responses. However, determining phase at the time of a stimulus with standard signal processing methods is not possible due to the stimulus artifact masking...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2020.116761
更新日期：2020-07-01 00:00:00
abstract：:Pre-stimulus α power has been shown to correlate with the behavioral accuracy of perceptual decisions. In most cases, these correlations have been observed by comparing α power for different behavioral outcomes (e.g. correct vs incorrect trials). In this paper we investigate such covariation within the context of beha...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2013.10.041
更新日期：2014-02-15 00:00:00
abstract：:Friston et al. (1995, NeuroImage 2:45-53) presented a method for detecting activations in fMRI time-series based on the general linear model and a heuristic analysis of the effective degrees of freedom. In this communication we present corrected results that replace those of the previous paper and solve the same probl...
journal_title：NeuroImage
pub_type： 评论,杂志文章
doi：10.1006/nimg.1995.1023
更新日期：1995-09-01 00:00:00
abstract：:The entwined nature of perceptual and conceptual processes renders an understanding of the interplay between perceptual recognition and conceptual access a continuing challenge. Here, to disentangle perceptual and conceptual processing in the brain, we combine magnetoencephalography (MEG), picture and word presentatio...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2020.116913
更新日期：2020-10-01 00:00:00
abstract：:Schizophrenia is associated with fronto-temporal dysconnectivity, but it is not clear whether this is a risk factor for the disorder or is a consequence of the established illness. The aim of the present study was to use fMRI to investigate fronto-temporal connectivity in subjects with prodromal signs of schizophrenia...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2009.08.038
更新日期：2010-01-01 00:00:00
abstract：:The neural mechanisms underlying conscious visual perception have been extensively investigated using bistable perception paradigms. Previous functional magnetic resonance imaging (fMRI) and transcranial magnetic stimulation (TMS) studies suggest that the right anterior superior parietal (r-aSPL) and the right posteri...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2014.12.018
更新日期：2015-02-15 00:00:00
abstract：:The length of a vocal tract is reflected in the sound it is producing. The length of the vocal tract is correlated with body size and humans are very good at making size judgments based on the acoustic effect of vocal tract length only. Here we investigate the underlying mechanism for processing this main auditory cue...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2006.02.045
更新日期：2006-08-01 00:00:00
abstract：:Repetitive head impacts represent a risk factor for neurological impairment in team-sport athletes. In the absence of symptoms, a physiological basis for acute injury has not been elucidated. A basic brain function that is disrupted after mild traumatic brain injury is the regulation of homeostasis, instantiated by ac...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2020.117306
更新日期：2020-12-01 00:00:00
abstract：:Models of healthy brain function and psychiatric conditions assume that excitatory and inhibitory activity are balanced in the human brain at multiple spatial and temporal scales. In human neuroimaging, concentrations of the major excitatory (glutamate) and inhibitory (γ-aminobutyric acid, GABA) neurotransmitters are ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2020.117112
更新日期：2020-10-15 00:00:00
abstract：:General cognitive ability (GCA) has substantial explanatory power for behavioral and health outcomes, but its cortical substrate is still not fully established. GCA is highly polygenic and research to date strongly suggests that its cortical substrate is highly polyregional. We show in map-based and region-of-interest...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2016.01.049
更新日期：2016-04-01 00:00:00
abstract：:Recent multi-voxel pattern classification (MVPC) studies have shown that in early visual cortex patterns of brain activity generated during mental imagery are similar to patterns of activity generated during perception. This finding implies that low-level visual features (e.g., space, spatial frequency, and orientatio...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2014.10.018
更新日期：2015-01-15 00:00:00
abstract：:Recent hemodynamic imaging studies have shown that processing of low probability task-relevant target stimuli (i.e., oddballs) and low probability task-irrelevant novel stimuli elicit widespread activity in diverse, spatially distributed cortical and subcortical systems. The nature of this distributed response support...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2004.12.035
更新日期：2005-04-15 00:00:00
abstract：:Intraoperative Thermal Imaging (ITI) is a novel neuroimaging technique that can potentially locate the margins of primary and metastatic brain tumors. As a result, the additional real-time anatomical and pathophysiological information may significantly contribute to an improved extent of tumor resection. Our objective...
journal_title：NeuroImage
pub_type： 杂志文章,评审
doi：10.1016/j.neuroimage.2009.03.043
更新日期：2009-08-01 00:00:00
abstract：INTRODUCTION:The brain representation of visceral stimulation bears important similarities to that of somatic stimulation. However, the role of the primary (S1) and secondary (S2) somatosensory cortices in mediating gastric sensation is uncertain. MATERIALS AND METHODS:Eighteen healthy, right-handed volunteers (age 32...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2006.07.033
更新日期：2007-01-15 00:00:00
abstract：:This study aimed to determine regional pattern of tissue perfusion in the normal-appearing white matter (NAWM) of patients with primary-progressive (PP), relapsing-remitting (RR) multiple sclerosis (MS) and healthy controls, and to investigate the association between perfusion abnormalities and clinical disability. Us...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2006.08.008
更新日期：2006-12-01 00:00:00
