Abstract：
:Endocrine Disrupting Chemicals (EDCs) have the potential to alter hormone pathways that regulate reproductive processes in wildlife and fishes. In this research the hypothesis that Mediterranean top predator species (such as large pelagic fish) are potentially at risk due to EDCs is investigated. These marine organisms tend to accumulate high concentrations of EDCs such as polyhalogenated aromatic hydrocarbons (PHAHs). The potential effects of EDCs on a fish species of commercial interest, the top predator Xiphias gladius (swordfish), were investigated using vitellogenin (Vtg) and Zona radiata proteins (Zrp) as diagnostic and prognostic biomarkers. Dramatic induction of typically female proteins (Vtg and Zrp) was detected by ELISA and Western Blot in adult males of the species. These results are the first warning of the potential risk for reproductive function of Mediterranean top predators, and suggest the need for continuous monitoring of this fragile marine environment.
journal_name
Mar Environ Resjournal_title
Marine environmental researchauthors
Fossi MC,Casini S,Ancora S,Moscatelli A,Ausili A,Notarbartolo-di-Sciara Gdoi
10.1016/s0141-1136(01)00107-6keywords:
subject
Has Abstractpub_date
2001-12-01 00:00:00pages
477-83issue
5eissn
0141-1136issn
1879-0291pii
S0141-1136(01)00107-6journal_volume
52pub_type
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