Abstract：
:The multixenobiotic resistance (MXR) mechanism, mediated by activity of the transmembrane P-glycoprotein, represents a basic biological defence system in aquatic organisms. Here we investigate the MXR transport activity in an aquatic vertebrate, the common carp (Cyprinus carpio). We measured the accumulation rate of a model MXR substrate, the fluorescent dye rhodamine B (RB), in gills, lateral muscles, liver and bile. Results obtained using this method showed a significant increase of RB accumulation in tissues of fish exposed for I h to 3 microM RB in the presence of the model MXR inhibitors cyclosporin A (CA, 5 microM) or verapamil (VER, 10 microM), when compared with specimens exposed without inhibitors. The highest increase in RB accumulation detected in the liver (VER 54%, CA 170%) indicates that among the tissues analysed within this study, liver is the most prominent candidate organ for the functional detection of MXR activity in C. carpio.
journal_name
Mar Environ Resjournal_title
Marine environmental researchauthors
Smital T,Sauerborn Rdoi
10.1016/s0141-1136(02)00155-1keywords:
subject
Has Abstractpub_date
2002-09-01 00:00:00pages
449-53issue
3-5eissn
0141-1136issn
1879-0291pii
S0141-1136(02)00155-1journal_volume
54pub_type
杂志文章abstract：:The option of storing CO(2) in subsea rock formations to mitigate future increases in atmospheric CO(2) may induce problems for animals in the deep sea. In the present study the deep-sea bivalve Acesta excavata was subjected to environmental hypercapnia (pHSW 6.35, P(CO₂) =33,000 μatm) corresponding to conditions repo...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2011.07.002
更新日期：2011-09-01 00:00:00
abstract：:In future global change scenarios the surface ocean will experience continuous acidification and rising temperatures. While effects of both stressors on marine, benthic communities are fairly well studied, consequences of the interaction of both factors remain largely unknown. We performed a short-term microcosm exper...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2017.11.002
更新日期：2018-02-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2015.02.001
更新日期：2015-04-01 00:00:00
abstract：:The Water Framework Directives aims a reduction in concentration of hazardous substances in the marine environment. Consequently, there is a need to distinguish between anthropogenically influenced metal concentrations from natural background levels. To better achieve this goal in the Portuguese coast, dissolved and p...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2012.05.010
更新日期：2012-08-01 00:00:00
abstract：:Pelagic seabirds exhibit plasticity in foraging characteristics in relation to oceanographic conditions. This should be particularly relevant in tropical marine environments where food resources are naturally more unpredictable. We studied how inter-annual variations (2013-2018) in tropical oceanographic conditions (d...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2020.105165
更新日期：2020-12-01 00:00:00
abstract：:The conspicuous, red harpacticoid Metis holothuriae grows to a large size (∼600 μm length) and accounts for 29.51% of the numerical meiofaunal abundance within blooms of the toxic, benthic cyanobacterium Lyngbya majuscula. Despite this, the meiobenthic juvenile trumpeter whiting, Sillago maculata, consume M. holothuri...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2011.12.001
更新日期：2012-03-01 00:00:00
abstract：:Ostreopsis blooms regularly occur in many Mediterranean coastal areas in late summer-autumn. In the northern Adriatic Sea, Ostreopsis blooms affect diatom-dominated microphytobenthic communities. In this study, the effects of the filtrates of some diatom species, both benthic (Tabularia affinis, Proschkinia complanato...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2017.09.016
更新日期：2017-10-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2015.03.006
更新日期：2015-05-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(99)00077-x
更新日期：2000-04-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2004.03.100
更新日期：2004-08-01 00:00:00
abstract：:To investigate the biological impact of polycyclic aromatic hydrocarbons (PAHs) on reproductive system, scallops Chlamys farreri were continuously exposed to benzo[a]pyrene (BaP) (0.5, 3, 10microgL(-1)) during 15 days. DNA damage and histological alterations were examined in female gonad. DNA strand break levels signi...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2008.10.006
更新日期：2009-02-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2020.105011
更新日期：2020-07-01 00:00:00
abstract：:The influence of nutrient availability and light conditions on phytoplankton size-structure, nutritional strategy and production was studied in a phosphorus-poor estuary in the northern Baltic Sea receiving humic-rich river water. The relative biomass of mixotrophic nanophytoplankton peaked in spring when heterotrophi...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2019.104778
更新日期：2019-10-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2004.03.053
更新日期：2004-08-01 00:00:00
abstract：:This work evaluates the impact of phytoplankton blooms on metal availability driven by dredging, in an area of the Sado estuary (Portugal), subject to ongoing dredging operations during the entire sampling period. In situ changes of chlorophyll a concentration, bioavailable trace metals (Cr, Mn, Co, Ni, Cu, Zn, Cd and...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2019.104837
更新日期：2019-11-06 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2011.09.012
更新日期：2012-04-01 00:00:00
abstract：:The indiscriminate use of plastic has greatly increased microplastic contamination risk in the marine environment. Microplastics can affect all marine life via the food web, from primary producers (e.g., microalgae) to final consumers (e.g., carnivorous fish). Thus, several studies have attempted to evaluate microplas...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2019.104838
更新日期：2019-11-09 00:00:00
abstract：:Mounting evidence suggests that the P-glycoprotein (pgp) efflux pump may be a modulator of bioavailability and a mode of excretion for xenobiotics. Immunohistochemistry was utilized to examine the distribution and inducibility of a pgp like protein in catfish. Immunoreactivity to the MDR C-219 monoclonal antibody was ...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(00)00116-1
更新日期：2000-07-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2017.10.015
更新日期：2017-12-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2013.08.013
更新日期：2013-12-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2010.01.005
更新日期：2010-01-01 00:00:00
abstract：:Faunal assemblages of subtidal sedimentary environments are key components of coastal ecosystems. Benthic communities inhabiting the coastal zone near urban centers in Concepción Bay (Chile) have been described as highly disturbed (i.e. impoverished in diversity and species richness). This is due to the frequent prese...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2017.07.022
更新日期：2017-09-01 00:00:00
abstract：:Habitat mapping is essential for the management and conservation of coastal marine habitats. However, accurate and up-to-date habitat maps are rarely available for the marine realm. In this study, we mapped the coastal marine habitats of >400 km of coastline in the north-western United Arab Emirates (UAE) using a comb...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2020.105095
更新日期：2020-10-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2014.02.004
更新日期：2014-05-01 00:00:00
abstract：:Aquatic organisms are constantly exposed to both physical (e.g. temperature and salinity variations) and chemical (e.g. endocrine disruptor chemicals, heavy metals, hydrocarbons, diatom toxins, and other toxicants) stressors which they react to by activating a series of defense mechanisms. This paper reviews the liter...
journal_title：Marine environmental research
pub_type： 杂志文章,评审
doi：10.1016/j.marenvres.2011.09.015
更新日期：2012-05-01 00:00:00
abstract：:The macroalga Caulerpa prolifera colonized the Mar Menor coastal lagoon after the enlargement of the main inlet in 1972, coexisting now with the previous Cymodocea nodosa meadows. The physiological response and the photoacclimation capacity of both species were studied. For this purpose in vivo chlorophyll a fluoresce...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2012.05.001
更新日期：2012-08-01 00:00:00
abstract：:Coastal sediments subjected to high anthropogenic impacts can accumulate large amounts of polycyclic aromatic hydrocarbons (PAHs) and metals, demanding effective and eco-sustainable remediation solutions. In this study, we carried out bioremediation experiments on marine sediments highly contaminated with PAHs and met...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2020.105101
更新日期：2020-12-01 00:00:00
abstract：:Metal transport in mollusk extrapallial fluid (EPF) that acts as a "bridge" between soft tissues and shell has surprisingly received little attention until now. Using ultrafiltration and radiotracer techniques we determined silver concentrations and speciation in the EPF of the blue mussel Mytilus edulis after short-t...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2010.09.004
更新日期：2011-02-01 00:00:00
abstract：:In this study, new DNA markers were explored for the flounder Platichthys flesus. cDNA and genomic sequences of the genes encoding the glyceraldehyde-3-phosphate-deshydrogenase (GAPDH), the cytosolic creatine kinase (CK), the prostaglandin D synthase (PGDS) and the betaine homocysteine methyltransferase (BHMT) were ch...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2010.05.002
更新日期：2010-08-01 00:00:00
abstract：:The methods of proteomics, the study of the protein complement of the genome, are applicable to environmental testing. Sets of proteins specific to different stressors can be isolated using computer imaging software. Individual proteins can be identified by mass spectrometry. The Protein Expression Signatures (PES) ob...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(02)00115-0
更新日期：2002-09-01 00:00:00
