Ectopic osteogenesis with biphasic ceramics of hydroxyapatite and tricalcium phosphate in rabbits.

abstract：:Autophagy has attracted a great deal of research interest in tumor therapy in recent years. An attempt was made in this direction and now we report that iron oxide NPs synthesized by us selectively induce autophagy in cancer cells (A549) and not in normal cells (IMR-90). It was also noteworthy that autophagy correlate...

journal_title：Biomaterials

authors： Khan MI,Mohammad A,Patil G,Naqvi SA,Chauhan LK,Ahmad I

更新日期：2012-02-01 00:00:00

abstract：:Approximately 285 million people worldwide suffer from diabetes, with insulin supplementation as the most common treatment measure. Regenerative medicine approaches such as a bioengineered pancreas has been proposed as potential therapeutic alternatives. A bioengineered pancreas will benefit from the development of a ...

journal_title：Biomaterials

authors： Goh SK,Bertera S,Olsen P,Candiello JE,Halfter W,Uechi G,Balasubramani M,Johnson SA,Sicari BM,Kollar E,Badylak SF,Banerjee I

更新日期：2013-09-01 00:00:00

abstract：:In order to develop a more effective self-etching primer, with a longer lasting shelf life, we designed a self-etching primer comprised of methacrylamide, N-methacryloyl glycine, NMGly. In this study, the hydrolytic stability of the amide portion in the NMGly was examined. The difference in the hydrolytic stability be...

journal_title：Biomaterials

authors： Nishiyama N,Suzuki K,Yoshida H,Teshima H,Nemoto K

更新日期：2004-03-01 00:00:00

abstract：:Macropores in tissue engineering scaffolds provide space for vascularization, cell-proliferation and cellular interactions, and is crucial for successful tissue regeneration. Modulating the size and density of macropores may promote desirable cellular processes at different stages of tissue development. Most current t...

journal_title：Biomaterials

authors： Han LH,Lai JH,Yu S,Yang F

更新日期：2013-06-01 00:00:00

abstract：:Methyl methacrylate (MMA) is a volatile liquid widely used in the manufacture of acrylic polymers. In modern dentistry, MMA is the mainstream material in denture bases. MMA has been implicated as primary irritant and sensitizer, which can cause allergic eczematous reaction on the oral mucosa as well as skin. To date, ...

journal_title：Biomaterials

authors： Yang HW,Chou LS,Chou MY,Chang YC

更新日期：2003-08-01 00:00:00

abstract：:This study examines the early shrinkage behaviour of dental composite resins, and in particular the interfacial stresses around the margins of a composite restoration. The development of stresses at the restoration-tooth interface can have a detrimental effect on the longevity of a restoration. The influence of this i...

journal_title：Biomaterials

authors： Ensaff H,O'Doherty DM,Jacobsen PH

更新日期：2001-12-01 00:00:00

abstract：:Ex-vivo blood-brain barrier (BBB) model is of great value for studying brain function and drug development, but it is still challenging to engineer macroscale three-dimensional (3D) tissue constructs to recapitulate physiological and functional aspects of BBB. Here, we describe a delicate 3D vascularized neural constr...

journal_title：Biomaterials

authors： Yue H,Xie K,Ji X,Xu B,Wang C,Shi P

更新日期：2020-07-01 00:00:00

abstract：:In vitro solubility tests of hydroxyapatite, tetracalcium phosphate or tricalcium phosphate particles were performed in lactate, citrate, Gomoris or Michaelis buffer with pH 6.2 or 7.2 and in aqua destillata. The results showed that in general the solubility decreased in the order tetracalcium phosphate greater than t...

journal_title：Biomaterials

authors： Klein CP,de Blieck-Hogervorst JM,Wolke JG,de Groot K

更新日期：1990-09-01 00:00:00

abstract：:Despite serving as the clinical "gold standard" treatment for critical size bone defects, decellularized allografts suffer from long-term failure rates of ~60% due to the absence of the periosteum. Stem and osteoprogenitor cells within the periosteum orchestrate autograft healing through host cell recruitment, which i...

journal_title：Biomaterials

authors： Li Y,Hoffman MD,Benoit DSW

更新日期：2021-01-01 00:00:00

abstract：:Immunotherapy has shown promising treatment effects for a variety of cancers. However, the immune treatment efficiency for solid tumors is limited owing to insufficient infiltration of immune cells into solid tumors. The conversion of tumor-supportive macrophages to tumor-suppressive macrophages, inducing the function...

journal_title：Biomaterials

authors： Wang Y,Lin YX,Qiao SL,An HW,Ma Y,Qiao ZY,Rajapaksha RP,Wang H

更新日期：2017-01-01 00:00:00

abstract：:Bone tissue is an anisotropic non-homogeneous composite material composed of inorganic, bone mineral fibres (hydroxyapatite) embedded in an organic matrix (type I collagen and non-collagenous proteins). Factors contributing to the overall mechanical behaviour include constituent volume fraction, mechanical properties,...

journal_title：Biomaterials

authors： Walsh WR,Guzelsu N

更新日期：1994-01-01 00:00:00

abstract：:A range of poly(alkyl methacrylate)s in the range C5 to C13 with varying degrees of crosslinking, have been studied with respect to stress-strain behaviour. Where the extensions to break were sufficiently high, stress-strain properties conformed well to the statistical theory of rubber elasticity, the Mooney/Rivlin C2...

journal_title：Biomaterials

authors： Davy KW,Braden M

更新日期：1987-09-01 00:00:00

abstract：:Crystalline carbonate- and sodium-and-carbonate-substituted hydroxyapatite (CO3HAp and NaCO3HAp) powders were prepared at room temperature via a heterogeneous reaction between Ca(OH)2/CaCO3/Na2CO3 and (NH4)2HPO4 aqueous solution using the mechanochemical hydrothermal route. X-ray diffraction, infrared spectroscopy, th...

journal_title：Biomaterials

authors： Suchanek WL,Shuk P,Byrappa K,Riman RE,TenHuisen KS,Janas VF

更新日期：2002-02-01 00:00:00

abstract：:Natural particles ranging from various cell membranes to nascent proteins are highly optimized for their specific functions in vivo and possess features that are desired in drug delivery carriers. However, the current endeavor in research on bioparticles is still seeking the appropriate strategy to shield multiple age...

journal_title：Biomaterials

authors： Wang R,Zhang C,Li J,Huang J,Opoku-Damoah Y,Sun B,Zhou J,Di L,Ding Y

更新日期：2019-11-01 00:00:00

abstract：:Redox-sensitive non-viral delivery systems exploit intracellular reducing environment to improve the efficacy of the delivery of nucleic acids by selectively releasing the cargo in the subcellular space. Bcl-2 overexpression is frequently observed in human cancers and is closely associated with increased resistance to...

journal_title：Biomaterials

authors： Manickam DS,Hirata A,Putt DA,Lash LH,Hirata F,Oupický D

更新日期：2008-06-01 00:00:00

abstract：:IR-780 iodide is a near-infrared (NIR) fluorescence dye with higher and more stable fluorescence intensity than clinically applied dye indocyanine green (ICG). Meanwhile, IR-780 can be utilized in photothermal therapy with laser irradiation. IR-780 is an important theranostic agent but its lipophilicity limited its ap...

journal_title：Biomaterials

authors： Yue C,Liu P,Zheng M,Zhao P,Wang Y,Ma Y,Cai L

更新日期：2013-09-01 00:00:00

abstract：:A number of neurodegenerative disorders may potentially be treated by the delivery of therapeutic genes to neurons. Nonviral gene delivery systems, however, typically provide low transfection efficiency in post-mitotic differentiated neurons. To uncover mechanistic reasons for this observation, we compared gene transf...

journal_title：Biomaterials

authors： Suk JS,Suh J,Choy K,Lai SK,Fu J,Hanes J

更新日期：2006-10-01 00:00:00

abstract：:Excessive production of reactive oxygen species (ROS) is a hallmark feature in nanomaterials (NMs) induced cellular toxicity. However, the inter-relationship between NMs induced ROS generation and the cells innate ability to regulate intracellular ROS level in effecting a particular cellular outcome is currently under...

journal_title：Biomaterials

authors： Setyawati MI,Tay CY,Leong DT

更新日期：2013-12-01 00:00:00

abstract：:The anodic behaviour of Ni-Cr dental alloys used as porcelain substrates has been investigated in both as-cast and thermal treated conditions. Polarization curves and scratching at constant potentials in synthetic salivas have shown that breakdown potentials are not influenced by the elimination of passive films cover...

journal_title：Biomaterials

authors： de De Micheli SM,Riesgo O

更新日期：1982-10-01 00:00:00

abstract：:Patient-derived tumor organoids offer potentially useful models of cancer tissue physiology. Yet, conventional organoid cultures utilize generic matrices that are difficult to tailor for various unique tumor microenvironments. Here, we employ synthetic, enzymatically crosslinked hydrogels to define mechanical and bioc...

journal_title：Biomaterials

authors： Ng S,Tan WJ,Pek MMX,Tan MH,Kurisawa M

更新日期：2019-10-01 00:00:00

abstract：:A pH-sensitive molecularly imprinted polymer (MIP) nanospheres/hydrogel composite exhibiting controlled release of dexamethasone-21 phosphate disodium (DXP) was developed as a potential coating for implantable biosensors to improve their biocompatibility. The molecularly imprinted pH-sensitive nanospheres were prepare...

journal_title：Biomaterials

authors： Wang C,Javadi A,Ghaffari M,Gong S

更新日期：2010-06-01 00:00:00

abstract：:Photopolymerized hydrogels are being investigated for a number of tissue engineering applications because of the ability to form these materials in situ in a minimally invasive manner such as by injection. In addition, hydrogels, three-dimensional networks of hydrophilic polymers that are able to swell large amounts o...

journal_title：Biomaterials

authors： Nguyen KT,West JL

更新日期：2002-11-01 00:00:00

abstract：:Ectopic expression of heme oxygenase-1 (HO-1) in ischemic tissue protects the tissue from apoptosis and necrosis and promotes angiogenesis. However, apoptosis and necrosis will decrease HO-1 gene transfection efficacy. We hypothesized that fibroblast growth factor-2 (FGF2) would attenuate ischemic damage during the in...

journal_title：Biomaterials

authors： Bhang SH,Kim JH,Yang HS,La WG,Lee TJ,Sun AY,Kim GH,Lee M,Kim BS

更新日期：2009-10-01 00:00:00

abstract：:The influence of processing-introduced flaws and heat treatment on the strength degradation of the dental core material has recently been observed. However, there are insufficient studies which investigate the role of grinding, grinding orientation, sandblasting, polishing and heat treatment on the strength of In-Cera...

journal_title：Biomaterials

authors： Guazzato M,Albakry M,Quach L,Swain MV

更新日期：2004-05-01 00:00:00

abstract：:The FRP wires 0.5 mm in diameter with a multiple fiber structure were fabricated by drawing the fiber polymer complex at 250 degrees C for an esthetic, transparent orthodontic wire. Biocompatible CaO-P2O5-SiO2-Al2O3 (CPSA) glass fibers of 8-20 microm in diameter were oriented unidirectionally in the longitudinal direc...

journal_title：Biomaterials

authors： Imai T,Watari F,Yamagata S,Kobayashi M,Nagayama K,Toyoizumi Y,Nakamura S

更新日期：1998-12-01 00:00:00

abstract：:Bioelectrical phenomenon in natural bone has been well recognized for its role in bone development and fracture healing. For example, the piezoelectricity induced modulation in cellular functionality assists in the repair and regeneration of bone tissue. Against this backdrop, we review here the origin of dielectric a...

journal_title：Biomaterials

authors： Khare D,Basu B,Dubey AK

更新日期：2020-11-01 00:00:00

abstract：:Here, we report the safety, tumor accumulation and potential of polyethylene glycol-grafted graphene oxide (pGO) as a multimodal nanocarrier of photosensitizers and synergistic anticancer agents. First, both graphene oxide (GO) and pGO were synthesized, and their in vitro and in vivo toxicities were tested. When 80 mg...

journal_title：Biomaterials

authors： Miao W,Shim G,Lee S,Lee S,Choe YS,Oh YK

更新日期：2013-04-01 00:00:00

abstract：:Matrix remodeling plays a fundamental role in physiological and pathological processes, as well as in tissue engineering applications. In this paper, optical coherence tomography (OCT), a non-destructive optical imaging technology, was used to image collagen gel remodeling by smooth muscle cells (SMCs). The optical sc...

journal_title：Biomaterials

authors： Levitz D,Hinds MT,Ardeshiri A,Hanson SR,Jacques SL

更新日期：2010-11-01 00:00:00

abstract：:One of the potential factors that may affect the results of mesenchymal stem cell (MSC)-based therapy is the age of donors and recipients. However, there have been no controlled studies to investigate the influence of skeletal maturity on the MSC-based repair of cartilage. The purpose of this study was to compare the ...

journal_title：Biomaterials

authors： Shimomura K,Ando W,Tateishi K,Nansai R,Fujie H,Hart DA,Kohda H,Kita K,Kanamoto T,Mae T,Nakata K,Shino K,Yoshikawa H,Nakamura N

更新日期：2010-11-01 00:00:00

abstract：:The ability of different calcium phosphate to activate the complement system is studied by crossed immunoelectrophoresis demonstrating conversion of C3 to C3b. Complement consumption is determined by a haemolytic assay CH50. Hydroxyapatite powders after sintering induce a significant conversion of C3 and reduction of ...

journal_title：Biomaterials

authors： Klein CP,de Groot K,van Kamp G

更新日期：1983-07-01 00:00:00