Recombinant Yersinia YopT leads to uncoupling of RhoA-effector interaction.

abstract：:A superoxide dismutase (SOD) gene from the obligate intracellular bacterium Coxiella burnetii has been cloned, and its DNA sequence has been determined and expressed in Escherichia coli. The gene was identified on pSJR50, a pHC79-derived genomic clone, by using the polymerase chain reaction with degenerate oligonucleo...

journal_title：Infection and immunity

authors： Heinzen RA,Frazier ME,Mallavia LP

更新日期：1992-09-01 00:00:00

abstract：:The gastric pathogen helicobacter pylori is one of a number of bacteria which bind specifically to gangliotetraosylceramide, gangliotriaosylceramide, and phosphatidylethanolamine in vitro at neutral pH. Since this organism encounters an acid pH during initial infection of the stomach, we have monitored the effect of p...

journal_title：Infection and immunity

authors： Huesca M,Borgia S,Hoffman P,Lingwood CA

更新日期：1996-07-01 00:00:00

abstract：:Peptic ulcer disease (PUD) occurs after a long-term Helicobacter pylori infection. However, the disease can develop earlier, and rare cases have been observed in children, suggesting that these H. pylori strains may be more virulent. We used suppressive subtractive hybridization for comparative genomics between H. pyl...

journal_title：Infection and immunity

authors： Oleastro M,Monteiro L,Lehours P,Mégraud F,Ménard A

更新日期：2006-07-01 00:00:00

abstract：:Streptococcus mutans is one of the best-known biofilm-forming organisms associated with humans. We investigated the role of the sortase gene (srtA) in monospecies biofilm formation and observed that inactivation of srtA caused a decrease in biofilm formation. Genes encoding three putative sortase-dependent proteins we...

journal_title：Infection and immunity

authors： Lévesque CM,Voronejskaia E,Huang YC,Mair RW,Ellen RP,Cvitkovitch DG

更新日期：2005-06-01 00:00:00

abstract：:Purification of the envelope antigen of Yersinia pestis EV with passive hemagglutination activity is described. The purification procedure consisted of pancreatin digestion, chromatography on human erythrocyte stroma set on Celite, and rechromatography on Sephadex G-200. Chemical, physical, and biological properties o...

journal_title：Infection and immunity

authors： Głosnicka R,Gruszkiewicz E

更新日期：1980-11-01 00:00:00

abstract：:At least 10 of 11 demonstrable antigens in unheated culture filtrates of 12 vaccine strains of BCG were shared as determined in a reference antigen-antibody immunoelectrophoresis system. Filtrates from each of the BCG strains gave equivalent skin test reactions in homologously and heterologously sensitized guinea pigs...

journal_title：Infection and immunity

authors： Chaparas SD,Hedrick SR

更新日期：1973-05-01 00:00:00

abstract：:We produced anti-idiotype antibodies to antibody to lipid A from Eikenella corrodens. The ALA-1 monoclonal antibody (immunoglobulin M [IgM] isotype), which had already been produced in our laboratory (T. Kato, I. Takazoe, and K. Okuda, Infect. Immun. 57:656-659, 1989), had reacted strongly with lipid A from E. corrode...

journal_title：Infection and immunity

authors： Kato T,Takazoe I,Okuda K

更新日期：1990-02-01 00:00:00

abstract：:We investigated the ability of using monoclonal antibodies (MAbs) against anthrax protective antigen (PA), an anthrax exotoxin component, to modulate exotoxin cytotoxic activity on target macrophage cell lines. Anthrax PA plays a critical role in the pathogenesis of Bacillus anthracis infection. PA is the cell-binding...

journal_title：Infection and immunity

authors： Mohamed N,Li J,Ferreira CS,Little SF,Friedlander AM,Spitalny GL,Casey LS

更新日期：2004-06-01 00:00:00

abstract：:The humoral and cell-mediated immune responses of murine lymphocytes exposed to lead in vivo and in vitro were investigated. In vivo Pb was administered via the drinking water (0 to 10 mM) for 1 to 10 weeks. In vivo exposure of the mice to Pb did not alter significantly their plaque-forming cell response to sheep eryt...

journal_title：Infection and immunity

authors： Lawrence DA

更新日期：1981-01-01 00:00:00

abstract：:Ambient pH signaling involves a cascade of conserved Rim or Pal products in ascomycetous yeasts or filamentous fungi, respectively. Recent evidences in the fungi Aspergillus nidulans, Saccharomyces cerevisiae, Yarrowia lipolytica, and Candida albicans suggested that components of endosomal sorting complexes required f...

journal_title：Infection and immunity

authors： Cornet M,Bidard F,Schwarz P,Da Costa G,Blanchin-Roland S,Dromer F,Gaillardin C

更新日期：2005-12-01 00:00:00

abstract：:The bactericidal and opsonizing effects of normal human serum on six strains of Salmonella typhimurium LT-2 having different lipopolysaccharide (LPS) composition were demonstrated through five indices. Complement activity in the presence of antibody was important for the opsonization of all six strains and for the bac...

journal_title：Infection and immunity

authors： Shaio MF,Rowland H

更新日期：1985-09-01 00:00:00

abstract：:Loss of the actin filament capping protein CapG has no apparent effect on the phenotype of mice maintained under sterile conditions; however, bone marrow-derived macrophages from CapG(-/-) mice exhibited distinct motility defects. We examined the ability of CapG(-/-) mice to clear two intracellular bacteria, Listeria ...

journal_title：Infection and immunity

authors： Parikh SS,Litherland SA,Clare-Salzler MJ,Li W,Gulig PA,Southwick FS

更新日期：2003-11-01 00:00:00

abstract：:Oral inoculation of calves and steers with 10(10) CFU of Escherichia coli O157:H7 induced prompt and sustained increases in serum antibodies to O157 lipopolysaccharide. Neutralizing antibodies to verotoxin 1 also increased rapidly in most steers but more gradually in calves. None of the animals developed neutralizing ...

journal_title：Infection and immunity

authors： Johnson RP,Cray WC Jr,Johnson ST

更新日期：1996-05-01 00:00:00

abstract：:Encapsulated Streptococcus pneumoniae of serotypes 2, 9N, 14, 21, and 23F and an unencapsulated variant of type 2 pneumococci were efficiently phagocytosed by both aerobically and anaerobically incubated human leukocytes. In the presence of O2, the pneumococci rapidly lost their viability, whereas during anaerobiosis,...

journal_title：Infection and immunity

authors： Thore M,Löfgren S,Tärnvik A,Monsen T,Selstam E,Burman LG

更新日期：1985-01-01 00:00:00

abstract：:To produce chronic infection, microbial pathogens must escape host immune defenses. Infection with the human pathogenic fungus Cryptococcus neoformans is typically chronic. To understand the mechanism by which C. neoformans survives in tissue after the infection of immunocompetent hosts, we systematically studied the ...

journal_title：Infection and immunity

authors： Feldmesser M,Kress Y,Novikoff P,Casadevall A

更新日期：2000-07-01 00:00:00

abstract：:Murine bone marrow-derived macrophages were infected with a panel of virulent isolates of Mycobacterium tuberculosis including laboratory strains Erdman and H37Rv and various clinical isolates in order to determine the sensitivity of each of these strains to the antimycobacterial activities of macrophage-generated rea...

journal_title：Infection and immunity

authors： Rhoades ER,Orme IM

更新日期：1997-04-01 00:00:00

abstract：:Recurrent pulmonary infections with Staphylococcus aureus and Pseudomonas aeruginosa are a major problem in cystic fibrosis (CF), leading to severe and progressive deterioration of the respiratory tract. Fibronectin (FN) has a binding site(s) for S. aureus and Streptococcus pyogenes. This bacterial bindings site(s) wa...

journal_title：Infection and immunity

authors： Stanislawski L,Sorin M

更新日期：1991-03-01 00:00:00

abstract：:ZnCl2 over a very narrow concentration range was found to be mitogenic for hamster lymph node cells but not for thymocytes or splenocytes. Maximal leucine, [3H]uridine, and [3H]thymidine incorporation. Addition of 10 micron ZnCl2 was found to greatly enhance the stimulation observed with the B-lymphocyte mitogen lipop...

journal_title：Infection and immunity

authors： Hart DA

更新日期：1978-02-01 00:00:00

abstract：:The purpose of this study was to localize antigenic regions on the flagellin protein of Campylobacter jejuni 81116. This strain has two flagellin genes, flaA and flaB, which are 95% identical; only flaA seems to be expressed in motile C. jejuni 81116 cells. Fragments of flaA and flaB were cloned in the bacterial expre...

journal_title：Infection and immunity

authors： Nuijten PJ,van der Zeijst BA,Newell DG

更新日期：1991-03-01 00:00:00

abstract：:Fimbriae are colonization factors of the human pathogen Haemophilus influenzae in that they mediate bacterial adherence to human eukaryotic cells. The contribution of the major (HifA) and putative minor (HifD and HifE) subunits of H. influenzae fimbriae to fimbria-specific adherence was studied by using mutants that w...

journal_title：Infection and immunity

authors： van Ham SM,van Alphen L,Mooi FR,van Putten JP

更新日期：1995-12-01 00:00:00

abstract：:Modulation of myelopoiesis by three synthetic muramyl peptides was investigated in vivo. Two adjuvant-active compounds (N-acetylmuramyl dipeptide [MDP] and MDP-butyl-ester) elicited significant responses in DBA/2 mice characterized by a rise in the level of monocyte-macrophage colony-stimulating activity in serum, a p...

journal_title：Infection and immunity

authors： Galelli A,Chedid L

更新日期：1983-12-01 00:00:00

abstract：:There are no vaccines against boutonneuse fever and Rocky Mountain spotted fever. Previous studies have identified a Rickettsia rickettsii surface protein as a vaccine candidate and shown that an antigenically related protein is present in R. conorii, which causes boutonneuse fever. The gene encoding the R. rickettsii...

journal_title：Infection and immunity

authors： Vishwanath S,McDonald GA,Watkins NG

更新日期：1990-03-01 00:00:00

abstract：:A 75-kilodalton major protein (75K protein) was purified to homogeneity from the cell lysate fraction and the envelope of Bacteroides gingivalis 381. The 75K protein was originally present in the outer membrane or the outermost part of this organism as a large, stable complex with an apparent molecular weight of about...

journal_title：Infection and immunity

authors： Yoshimura F,Watanabe K,Takasawa T,Kawanami M,Kato H

更新日期：1989-11-01 00:00:00

abstract：:Proteins from human polymorphonuclear leukocyte granules were extracted with 0.2 M acetate, pH 4.0, and fractionated by Sephadex G-100 column chromatography. The fractions demonstrated selective bactericidal action against a deep rough cell wall mutant of Escherichia coli O111:B4 with rough lipopolysacharide and cell ...

journal_title：Infection and immunity

authors： Modrzakowski MC,Cooney MH,Martin LE,Spitznagel JK

更新日期：1979-03-01 00:00:00

abstract：:Previous work (P. Castric, F. J. Cassels, and R. W. Carlson, J. Biol. Chem. 276:26479-26485, 2001) has shown the Pseudomonas aeruginosa 1244 pilin glycan to be covalently bound to a serine residue. N-terminal sequencing of pilin fragments produced from endopeptidase treatment and identified by reaction with a glycan-s...

journal_title：Infection and immunity

authors： Comer JE,Marshall MA,Blanch VJ,Deal CD,Castric P

更新日期：2002-06-01 00:00:00

abstract：:Vaccine antigen-specific antibody-secreting cell (ASC) responses in peripheral blood of healthy adult volunteers were studied after oral immunization with a prototype enterotoxigenic Escherichia coli (ETEC) vaccine by means of the enzyme-linked immunospot technique. Three doses of vaccine consisting of formalin-killed...

journal_title：Infection and immunity

authors： Wennerås C,Svennerholm AM,Ahrén C,Czerkinsky C

更新日期：1992-07-01 00:00:00

abstract：:[1-(14)C]acetate is incorporated into lipids more rapidly by liver from Aeromonas salmonicida-infected trout than by normal trout liver, both in vitro and in vivo. The increase was, in general, about twofold to less than threefold. ...

journal_title：Infection and immunity

authors： Shieh HS

更新日期：1976-09-01 00:00:00

abstract：:The Alexander hepatoma cell line, PLC/PRF/5, was studied for evidence of hepatitis B virus markers and alpha-fetoprotein. Only hepatitis B surface antigen and alpha-fetoprotein were detected. Induction experiments with 5-iodo-2'-deoxyuridine and inoculation of chimpanzees with whole cells or tissue culture fluid did n...

journal_title：Infection and immunity

authors： Daemer RJ,Feinstone SM,Alexander JJ,Tully JG,London WT,Wong DC,Purcell RH

更新日期：1980-11-01 00:00:00

abstract：:The protective immunity conferred by T-cell subsets against infection with Treponema pallidum subsp. pertenue was studied. We demonstrated that hamster T cells can be separated into two subsets by monoclonal antibody (MAb) GK 1.5 (anti-L3T4) and MAb 38. Eighty-five percent of hamster thymocytes were L3T4+ and 87% were...

journal_title：Infection and immunity

authors： Liu H,Alder JD,Steiner BM,Stein-Streilein J,Lim L,Schell RF

更新日期：1991-02-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) glycoprotein gC was purified by affinity chromatography with an immunosorbent column containing monoclonal antibody to HSV-1 gC, and its reactivity with rabbit antisera was measured by enzyme-linked immunosorbent assay and sodium dodecyl sulfate-polyacrylamide gel electrophoretic an...

journal_title：Infection and immunity

authors： Zweig M,Heilman CJ Jr,Bladen SV,Showalter SD,Hampar B

更新日期：1983-08-01 00:00:00