Correlated fast X-ray and optical variability in the black-hole candidate XTE J1118+480.

abstract：:The detection of electron spins associated with single defects in solids is a critical operation for a range of quantum information and measurement applications under development. So far, it has been accomplished for only two defect centres in crystalline solids: phosphorus dopants in silicon, for which electrical rea...

journal_title：Nature

authors： Yin C,Rancic M,de Boo GG,Stavrias N,McCallum JC,Sellars MJ,Rogge S

更新日期：2013-05-02 00:00:00

abstract：:Some surprising facts about the most productive institutions emerge when Japanese life-science research is subject to a novel type of assessment. ...

journal_title：Nature

authors： Yamazaki S

更新日期：1994-11-10 00:00:00

abstract：:Substrates of the proteasome are recognized and unfolded by the regulatory particle, and then translocated into the core particle (CP) to be degraded. A hetero-hexameric ATPase ring, containing subunits Rpt1-6, is situated within the base subassembly of the regulatory particle. The ATPase ring sits atop the CP, with t...

journal_title：Nature

authors： Park S,Roelofs J,Kim W,Robert J,Schmidt M,Gygi SP,Finley D

更新日期：2009-06-11 00:00:00

abstract：: ...

journal_title：Nature

authors： Silver A

更新日期：2019-01-01 00:00:00

abstract：:The mineral olivine dominates the composition of the Earth's upper mantle and hence controls its mechanical behaviour and seismic anisotropy. Experiments at high temperature and moderate pressure, and extensive data on naturally deformed mantle rocks, have led to the conclusion that olivine at upper-mantle conditions ...

journal_title：Nature

authors： Mainprice D,Tommasi A,Couvy H,Cordier P,Frost DJ

更新日期：2005-02-17 00:00:00

abstract：:Q beta replicase, in the absence of added template, will synthesize RNA autocatalytically. A variety of small RNa species, termed '6S RNAs' are generated. As this reaction purportedly occurs in the absence of template, it has been termed 'de novo' RNA synthesis. The question of whether Q beta replicase can polymerize ...

journal_title：Nature

authors： Hill D,Blumenthal T

更新日期：1983-01-27 00:00:00

abstract：:With the discovery1 of superconductivity at 203 kelvin in H3S, attention returned to conventional superconductors with properties that can be described by the Bardeen-Cooper-Schrieffer and the Migdal-Eliashberg theories. Although these theories predict the possibility of room-temperature superconductivity in metals th...

journal_title：Nature

authors： Drozdov AP,Kong PP,Minkov VS,Besedin SP,Kuzovnikov MA,Mozaffari S,Balicas L,Balakirev FF,Graf DE,Prakapenka VB,Greenberg E,Knyazev DA,Tkacz M,Eremets MI

更新日期：2019-05-01 00:00:00

abstract：:The best spectrographs are limited in stability by their calibration light source. Laser frequency combs are the ideal calibrators for astronomical spectrographs. They emit a spectrum of lines that are equally spaced in frequency and that are as accurate and stable as the atomic clock relative to which the comb is sta...

journal_title：Nature

authors： Wilken T,Curto GL,Probst RA,Steinmetz T,Manescau A,Pasquini L,González Hernández JI,Rebolo R,Hänsch TW,Udem T,Holzwarth R

更新日期：2012-05-30 00:00:00

abstract：:There is a clear case for drug treatments to be selected according to the characteristics of an individual patient, in order to improve efficacy and reduce the number and severity of adverse drug reactions. However, such personalization of drug treatments requires the ability to predict how different individuals will ...

journal_title：Nature

authors： Clayton TA,Lindon JC,Cloarec O,Antti H,Charuel C,Hanton G,Provost JP,Le Net JL,Baker D,Walley RJ,Everett JR,Nicholson JK

更新日期：2006-04-20 00:00:00

abstract：:More than twenty types of retinal ganglion cells conduct visual information from the eye to the rest of the brain. Each retinal ganglion cell type tessellates the retina in a regular mosaic, so that every point in visual space is processed for visual primitives such as contrast and motion. This information flows to tw...

journal_title：Nature

authors： Feinberg EH,Meister M

更新日期：2015-03-12 00:00:00

abstract：:Quantum criticality is associated with a system composed of a nearly infinite number of interacting quantum degrees of freedom at zero temperature, and it implies that the system looks on average the same regardless of the time- and length scale on which it is observed. Electrons on the atomic scale do not exhibit suc...

journal_title：Nature

authors： van der Marel D,Molegraaf HJ,Zaanen J,Nussinov Z,Carbone F,Damascelli A,Eisaki H,Greven M,Kes PH,Li M

更新日期：2003-09-18 00:00:00

abstract：:Neurons in the developing rodent cortex are generated from radial glial cells that function as neural stem cells. These epithelial cells line the cerebral ventricles and generate intermediate progenitor cells that migrate into the subventricular zone (SVZ) and proliferate to increase neuronal number. The developing hu...

journal_title：Nature

authors： Hansen DV,Lui JH,Parker PR,Kriegstein AR

更新日期：2010-03-25 00:00:00

abstract：:Membrane-enclosed organelles, a defining characteristic of eukaryotic cells, are lost during differentiation of specific cell types such as reticulocytes (an intermediate in differentiation of erythrocytes), central fibre cells of the eye lens, and keratinocytes. The degradation of these organelles must be tightly reg...

journal_title：Nature

authors： van Leyen K,Duvoisin RM,Engelhardt H,Wiedmann M

更新日期：1998-09-24 00:00:00

abstract：:Zygotic genome activation in metazoans typically occurs several hours to a day after fertilization, and thus maternal RNAs and proteins drive early animal embryo development. In plants, despite several molecular studies of post-fertilization transcriptional activation, the timing of zygotic genome activation remains a...

journal_title：Nature

authors： Del Toro-De León G,García-Aguilar M,Gillmor CS

更新日期：2014-10-30 00:00:00

abstract：:Natural visual scenes are cluttered with multiple objects whose individual features must somehow be selectively linked (or 'bound') if perception is to coincide with reality. Recent neurophysiological evidence supports a 'binding-by-synchrony' hypothesis: neurons excited by features of the same object fire synchronous...

journal_title：Nature

authors： Thiele A,Stoner G

更新日期：2003-01-23 00:00:00

abstract：:Diatoms dominate the biomass of phytoplankton in nutrient-rich conditions and form the basis of some of the world's most productive marine food webs. The diatom nuclear genome contains genes with bacterial and plastid origins as well as genes of the secondary endosymbiotic host (the exosymbiont), yet little is known a...

journal_title：Nature

authors： Allen AE,Dupont CL,Oborník M,Horák A,Nunes-Nesi A,McCrow JP,Zheng H,Johnson DA,Hu H,Fernie AR,Bowler C

更新日期：2011-05-12 00:00:00

abstract：:The travelling salesman problem is a classical problem in the field of combinatorial optimization, concerned with efficient methods for maximizing or minimizing a function of many independent variables. Given the positions of N cities, which in the simplest case lie in the plane, what is the shortest closed tour in wh...

journal_title：Nature

authors： Durbin R,Willshaw D

更新日期：1987-04-16 00:00:00

abstract：:Living organisms rely on simultaneous reactions catalysed by mutually compatible and selective enzymes to synthesize complex natural products and other metabolites. To combine the advantages of these biological systems with the reactivity of artificial chemical catalysts, chemists have devised sequential, concurrent, ...

journal_title：Nature

authors： Litman ZC,Wang Y,Zhao H,Hartwig JF

更新日期：2018-08-01 00:00:00

abstract：:A key event in the domestication and breeding of the oil palm Elaeis guineensis was loss of the thick coconut-like shell surrounding the kernel. Modern E. guineensis has three fruit forms, dura (thick-shelled), pisifera (shell-less) and tenera (thin-shelled), a hybrid between dura and pisifera. The pisifera palm is us...

journal_title：Nature

authors： Singh R,Low ET,Ooi LC,Ong-Abdullah M,Ting NC,Nagappan J,Nookiah R,Amiruddin MD,Rosli R,Manaf MA,Chan KL,Halim MA,Azizi N,Lakey N,Smith SW,Budiman MA,Hogan M,Bacher B,Van Brunt A,Wang C,Ordway JM,Sambanthamurthi

更新日期：2013-08-15 00:00:00

abstract：:Cocaine is believed to work by blocking the dopamine transporter (DAT) and thereby increasing the availability of free dopamine within the brain. Although this concept is central to current cocaine research and to treatment development, a direct relationship between DAT blockade and the subjective effects of cocaine h...

journal_title：Nature

authors： Volkow ND,Wang GJ,Fischman MW,Foltin RW,Fowler JS,Abumrad NN,Vitkun S,Logan J,Gatley SJ,Pappas N,Hitzemann R,Shea CE

更新日期：1997-04-24 00:00:00

abstract：:Several of the thousands of human long non-coding RNAs (lncRNAs) have been functionally characterized; however, potential roles for lncRNAs in somatic tissue differentiation remain poorly understood. Here we show that a 3.7-kilobase lncRNA, terminal differentiation-induced ncRNA (TINCR), controls human epidermal diffe...

journal_title：Nature

authors： Kretz M,Siprashvili Z,Chu C,Webster DE,Zehnder A,Qu K,Lee CS,Flockhart RJ,Groff AF,Chow J,Johnston D,Kim GE,Spitale RC,Flynn RA,Zheng GX,Aiyer S,Raj A,Rinn JL,Chang HY,Khavari PA

更新日期：2013-01-10 00:00:00

abstract：:An increasing body of evidence points to mitochondrial dysfunction as a contributor to the molecular pathogenesis of neurodegenerative diseases such as Parkinson's disease. Recent studies of the Parkinson's disease associated genes PINK1 (ref. 2) and parkin (PARK2, ref. 3) indicate that they may act in a quality contr...

journal_title：Nature

authors： Hasson SA,Kane LA,Yamano K,Huang CH,Sliter DA,Buehler E,Wang C,Heman-Ackah SM,Hessa T,Guha R,Martin SE,Youle RJ

更新日期：2013-12-12 00:00:00

abstract：:Selective lowering of Abeta42 levels (the 42-residue isoform of the amyloid-beta peptide) with small-molecule gamma-secretase modulators (GSMs), such as some non-steroidal anti-inflammatory drugs, is a promising therapeutic approach for Alzheimer's disease. To identify the target of these agents we developed biotinyla...

journal_title：Nature

authors： Kukar TL,Ladd TB,Bann MA,Fraering PC,Narlawar R,Maharvi GM,Healy B,Chapman R,Welzel AT,Price RW,Moore B,Rangachari V,Cusack B,Eriksen J,Jansen-West K,Verbeeck C,Yager D,Eckman C,Ye W,Sagi S,Cottrell BA,Torpey J

更新日期：2008-06-12 00:00:00

abstract：:Aquaporin (AQP) water-channel proteins are freely permeated by water but not by ions or charged solutes. Although mammalian aquaporins were believed to be located in plasma membranes, rat AQP6 is restricted to intracellular vesicles in renal epithelia. Here we show that AQP6 is functionally distinct from other known a...

journal_title：Nature

authors： Yasui M,Hazama A,Kwon TH,Nielsen S,Guggino WB,Agre P

更新日期：1999-11-11 00:00:00

abstract：:Fault strength is a fundamental property of seismogenic zones, and its temporal changes can increase or decrease the likelihood of failure and the ultimate triggering of seismic events. Although changes in fault strength have been suggested to explain various phenomena, such as the remote triggering of seismicity, the...

journal_title：Nature

authors： Taira T,Silver PG,Niu F,Nadeau RM

更新日期：2009-10-01 00:00:00

abstract：:Chronic myeloid leukaemia (CML) is caused by a defined genetic abnormality that generates BCR-ABL, a constitutively active tyrosine kinase. It is widely believed that BCR-ABL activates Akt signalling that suppresses the forkhead O transcription factors (FOXO), supporting the proliferation or inhibiting the apoptosis o...

journal_title：Nature

authors： Naka K,Hoshii T,Muraguchi T,Tadokoro Y,Ooshio T,Kondo Y,Nakao S,Motoyama N,Hirao A

更新日期：2010-02-04 00:00:00

abstract：:The peptide-loading complex (PLC) is a transient, multisubunit membrane complex in the endoplasmic reticulum that is essential for establishing a hierarchical immune response. The PLC coordinates peptide translocation into the endoplasmic reticulum with loading and editing of major histocompatibility complex class I (...

journal_title：Nature

authors： Blees A,Januliene D,Hofmann T,Koller N,Schmidt C,Trowitzsch S,Moeller A,Tampé R

更新日期：2017-11-23 00:00:00

abstract：:The central nervous system (CNS) requires a tightly controlled environment free of toxins and pathogens to provide the proper chemical composition for neural function. This environment is maintained by the 'blood-brain barrier' (BBB), which is composed of blood vessels whose endothelial cells display specialized tight...

journal_title：Nature

authors： Ben-Zvi A,Lacoste B,Kur E,Andreone BJ,Mayshar Y,Yan H,Gu C

更新日期：2014-05-22 00:00:00

abstract：:The metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. Here we have determined three different crystal structures of the extracellular ligand-binding region of mGluR1--in a complex with glutamate and in two unliganded forms. ...

journal_title：Nature

authors： Kunishima N,Shimada Y,Tsuji Y,Sato T,Yamamoto M,Kumasaka T,Nakanishi S,Jingami H,Morikawa K

更新日期：2000-10-26 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature

authors： Cai W,Ng B,Geng T,Wu L,Santoso A,McPhaden MJ

更新日期：2020-12-01 00:00:00