[The plasma-protein-binding of Clindamycin Cephazolin and Cephradin in neonates and adults (author's transl)].

abstract：:The secretory IgA system is common to all mucosal membranes and is presumably of great importance for their defense. In addition to the secretory IgA antibodies produced in a mucosa in response to a local antigenic stimulus there is a spread of this type of IgA response via committed lymphocytes. They originate from c...

journal_title：Klinische Padiatrie

authors： Hanson LA,Andersson B,Carlsson B,Dahlgren U,Mellander L,Porras O,Svanborg Edén C,Söderström T

更新日期：1985-07-01 00:00:00

abstract：:Central nervous system (CNS) tumors account for the highest mortality among pediatric malignancies. Accurate diagnosis is essential for optimal clinical management. The increasing use of molecular diagnostics has opened up novel possibilities for more precise classification of CNS tumors. We here report a single-insti...

journal_title：Klinische Padiatrie

authors： Bächli H,Ecker J,van Tilburg C,Sturm D,Selt F,Sahm F,Koelsche C,Grund K,Sutter C,Pietsch T,Witt H,Herold-Mende C,von Deimling A,Jones D,Pfister S,Witt O,Milde T

更新日期：2018-10-01 00:00:00

abstract：:CML is a rare malignancy in childhood not yet being treated by an established protocol of the Society of Pediatric Oncology and Hematology (GPOH). Up to now only allogeneic bone marrow transplantation (BMT) offers a curative treatment option. After being enrolled into the study "CML-päd" patients with a matched siblin...

journal_title：Klinische Padiatrie

authors： Suttorp M,Lion T,Creutzig U,Klingebiel T,Gadner H

更新日期：1996-07-01 00:00:00

abstract：:The therapy of complicated Kaposiform hemangioendothelioma (KHE) is still difficult. We present the first case of laryngomalacia with simultaneous mammalian target of Rapamycin (mTOR)-positive KHE of the neck and thoracic inlet and concurrent Kasabach-Meritt Phenomenon (KMP) in an 11-month-old boy suffering life-threa...

journal_title：Klinische Padiatrie

authors： Schroeder U,Lauten M,Stichtenoth G,Gebhard MP,Buchholz M,Kaiser MM

更新日期：2014-11-01 00:00:00

abstract：:On our opinion one important indication for sonographic diagnosis in future are masses in the larynx area: in infancy or childhood mainly laryngeal papillomatosis. In one of our boy patients with massive laryngeal papillomatosis laser surgery was first performed at 15 months of age. After a second and third procedure ...

journal_title：Klinische Padiatrie

authors： Grunert D,Schöning M,Stier B,Klingebiel T

更新日期：1989-05-01 00:00:00

abstract：:Infectious complications are a major cause of morbidity and mortality in pediatric and adult patients undergoing hematopoietic stem cell transplantation. The incidence and the severity code of infections depend on the function of the host's immune system. This function is strongly correlated to the application of immu...

journal_title：Klinische Padiatrie

authors： Schuster FR,Laws HJ

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Acute viral bronchiolitis is a frequent disease in infancy. There is little knowledge on medical care of severely affected infants in different European countries. PATIENTS:Infants (n=146) with bronchiolitis requiring respiratory support in winter season 2015/2016 treated in either one of two regions in Cen...

journal_title：Klinische Padiatrie

authors： Dohna-Schwake C,Mücher K,Stehling F,Rothoeft T,Roll C,Brevis Nuńez F,Seiffert P,Heister P,Hofmann M,Stein A,Jacobs A,Zuzak T,Durand P,Felderhoff-Müser U,Tissières P

更新日期：2018-09-01 00:00:00

abstract：:Analysis of the cellular DNA content was carried out in 162 children with ALL and 34 children with AML admitted to the university children's hospital Münster between 1979 and 1984. DNA aneuploidies were identified at a similar frequency in ALL (40%) and AML (44%). However, the degree of DNA aneuploidies (DNA-index) wa...

journal_title：Klinische Padiatrie

authors： Ritter J,Hiddemann W,Wörmann B,Büchner T,Schellong G

更新日期：1985-05-01 00:00:00

abstract：:The investigation of Immunoglobulins-and Total protein concentrations in saliva of healthy children shows an agreement with literature, a maturation in individual development of the saliva-producing organs in the mouth. ...

journal_title：Klinische Padiatrie

authors： Tympner KD,Dörfler S

更新日期：1980-09-01 00:00:00

abstract：:Crohn's Disease and Ulcerative Colitis play a vital role in the differential diagnosis of inflammatory diseases of the colon during childhood. Pediatricians, radiologists, pediatric surgions and pediatric pathologists have been frequently confronted with the problem of distinguishing the two diseases. Morphologically,...

journal_title：Klinische Padiatrie

authors： Födisch HJ,Toledo R

更新日期：1978-03-01 00:00:00

abstract：:In the period from 1965 to 1979 biopsies from the oropharynx of 11 children with non-Hodgkin's lymphoma were collected at the Lymph Node Registry in Kiel. Palatine tonsil tissue was examined in all cases and, in addition, specimens from the retrolingual region of one child and the epipharynx of two patients. All biops...

journal_title：Klinische Padiatrie

authors： Schwarze EW,Mrowietz B,van Ackeren G

更新日期：1983-05-01 00:00:00

abstract：:The control of severe infectious complications by preventive strategies, early diagnosis of infections and empiric broad-spectrum antibiotic therapy contributed to a marked improvement of survival in children with cancer over the last 20 years. This article overviews of the importance of prevention of infectious compl...

journal_title：Klinische Padiatrie

authors： Fleischhack G,Simon A

更新日期：2001-09-01 00:00:00

abstract：:An eight-year old girl showing a X/X-translocation (45,X/46,Xt(X;X)(q26;p11)) is presented. Besides short stature and congenital heart-anomaly no other phenotypical abnormalities were present. In all cells containing the abnormal X-chromosome, the latter was late labeling as shown by autoradiography and BrdU-labeling....

journal_title：Klinische Padiatrie

authors： Wagenbichler P,Frisch H,Schnedl W

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:One of the strongest predictive factors for therapy outcome in childhood acute lymphoblastic leukaemia (ALL), treated according to ALL-BFM protocols, is the response to initial prednisone treatment. Prednisone response is characterized by the peripheral leukaemic blast count. The threshold value for the char...

journal_title：Klinische Padiatrie

authors： Lauten M,Stanulla M,Zimmermann M,Welte K,Riehm H,Schrappe M

更新日期：2001-07-01 00:00:00

abstract：:Neurological symptoms developed in a girl aged three-and-a-half years during treatment with nalidixic acid. The symptoms progressed even after the preparation had been discontinued, and culminated in the development of a transient intracranial pressure increase. ...

journal_title：Klinische Padiatrie

authors： Lorenz R

更新日期：1979-07-01 00:00:00

abstract：:In 55 high-risk neonates of different birth-weight and gestational age, transcutaneous pO2 (tcpO2) was continuously monitored during transports from the Obstetric Units to the Neonatal Intensive Care Units. We were able to demonstrate that the need for oxygen was overestimated in most of the children and thus FiO2 cou...

journal_title：Klinische Padiatrie

authors： Genz T,Genz S,Schöber JG,Bühlmeyer K

更新日期：1986-11-01 00:00:00

abstract：:The aetiology and pathogenesis of the Duchenne-type muscular dystrophy (pseudohypertrophic muscular dystrophy) are still largely unknown. The possibilities of treating the disease are rather limited. Treatment is the more successful, the earlier diagnosis was possible, and the earlier treatment is initiated. The CK-Sc...

journal_title：Klinische Padiatrie

authors： Beckmann R

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:Late effects become progressively more important for the evaluation of therapeutic success in paediatric oncology. Thus, in 1998, the Late Effects Surveillance System (LESS) started to register and assess multicentrally, prospectively and longitudinally late effects of treatment for the group of Ewing's, sof...

journal_title：Klinische Padiatrie

authors： Langer T,Stöhr W,Paulides M,Kremers A,Dörr HG,Göbel U,Beck JD

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:  Despite a reduction in hospitalizations due to acute alcohol intoxication in minors, alcohol consumption among children and adolescents still presents an alarming social and clinical phenomenon. This is amplified by presumably more severe clinical symptoms of the alcohol intoxication in children and adoles...

journal_title：Klinische Padiatrie

authors： Lozada CAQ,Bartels MB,Kieslich M

更新日期：2020-09-01 00:00:00

abstract：:The present clinical observation is related to a 14-year-old girl suffering from acute myeloid leukemia. The clinical course was complicated by episodes of severe enterocolitis, E. coli- septicemia, pancreatitis and pneumonia. In the course of continued cytostatic and antibiotic treatment a persistent asymptomatic Lac...

journal_title：Klinische Padiatrie

authors： Majcher-Peszynska J,Heine W,Richter I,Eggers G,Mohr C

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:First-line treatment in AML commonly included high cumulative doses of anthracyclines with an increasing risk of cardiotoxicity. Liposomal daunorubicin (L-DNR) is thought to be less cardiotoxic without impairment of efficacy. METHODS:The AML-BFM REZ 97 study included two reinduction blocks with L-DNR (2 x 6...

journal_title：Klinische Padiatrie

authors： Reinhardt D,Hempel G,Fleischhack G,Schulz A,Boos J,Creutzig U

更新日期：2002-07-01 00:00:00

abstract：:Corticosteroids for treatment or prevention of pulmonary disease are milestones in the management of preterm infants nowadays. Prenatal maternal administration as well as postnatal treatment of the mechanically ventilated preterm infant with bronchopulmonary dysplasia (BPD) are considered to be established concepts. H...

journal_title：Klinische Padiatrie

authors： Krause M

更新日期：1997-09-01 00:00:00

abstract：:A two month old boy with Fournier's Gangrene of the scrotum as a result of unnecessary needle puncture of the hydrocele is being reported. The importance of appropriate diagnosis operation and drug-therapy is also described. ...

journal_title：Klinische Padiatrie

authors： Heemann KF,Homann W,Pistor K

更新日期：1984-11-01 00:00:00

abstract：:A case of a severe heroin withdrawal syndrom in a newborn infant is reported. Diagnostic and therapeutic aspects of the disease are reviewed. ...

journal_title：Klinische Padiatrie

authors： Petrich C,Voss HV,Bretschneider A,Göbel U

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:In the German guidelines for prophylaxis of group B streptococcal (GBS) early onset sepsis in neonates (EOS), GBS screening of all pregnant women has been recommended, but is not yet included in the Maternity Directives. Aim of the study was to identify temporal trends in incidence of EOS and their associati...

journal_title：Klinische Padiatrie

authors： Sorg AL,Obermeier V,Armann J,Klemme M,von Kries R

更新日期：2021-01-01 00:00:00

abstract：:Neurofibromatosis type 1 is the most common of the phakomatoses and the clinical follow-up is an interdisciplinary challenge. The data of 27 patients with NF1 were systematically reviewed and compared to data from the literature. All of our patients had clinical signs of NF1. Besides the classic criteria café-au-lait ...

journal_title：Klinische Padiatrie

authors： Syrbe S,Eberle K,Strenge S,Bernhard MK,Herbertz S,Bierbach U,Hirsch W,Froster UG,Kiess W,Merkenschlager A

更新日期：2007-11-01 00:00:00

abstract：:Lysozyme levels were determined in the mucosa of gut in 80 children with chronic inflammatory bowel disease, malabsorption and acrodermatitis enteropathica.l Levels of lysozyme in the mucosa of colon were found to be significantly higher in cases with chronic inflammatory bowel disease, whereas in children with malabs...

journal_title：Klinische Padiatrie

authors： Dick W,Braun OH,Grosse KP,Riemann JF,Schmidt H

更新日期：1984-01-01 00:00:00

abstract：:Five patients with arteriovenous angiomas in the head (2 galea angiomas, 1 mixed form with extracranial and intracranial localization of the arteriovenous fistulas and 2 intracranial arteriovenous fistulas) were described. Four patients were examined as newborns or infants. Oximetric data, intracardial pressure and ci...

journal_title：Klinische Padiatrie

authors： Pohl V

更新日期：1976-05-01 00:00:00

abstract：:Radio-labelled antimyosin-monoclonal antibodies (AMA) have been introduced to demonstrate myocardial necrosis after cardiac infarction or in cardiac allograft transplants. As rhabdomyosarcoma (RMS) and leiomyosarcoma (LMS) are tumors of myogenic origin, thus often containing myosin, we decided to use the 111In-labelle...

journal_title：Klinische Padiatrie

authors： Koscielniak E,Reuland P,Schilling F,Feine U,Treuner J

更新日期：1990-07-01 00:00:00

abstract：:The case is described of a 6 months old infant who developed purulent pericarditis during the course of pneumonia. Pericarditis probably developed in this condition by contiguous spread from the pleura. Diagnosis of impending cardiac tamponade was masked by the occurrence of massive unilateral empyema. The management ...

journal_title：Klinische Padiatrie

authors： Beitzke A,Trittenwein G,Rigler B,Grubbauer HM,Suppan C

更新日期：1982-09-01 00:00:00