Essential role for estrogen in protection against Vibrio vulnificus-induced endotoxic shock.

abstract：:Leishmania amastigotes are intracellular protozoan parasites of mononuclear phagocytes which reside within parasitophorous vacuoles of phagolysosomal origin. The pH of these compartments was studied with the aim of elucidating strategies used by these microorganisms to evade the microbicidal mechanisms of their host c...

journal_title：Infection and immunity

authors： Antoine JC,Prina E,Jouanne C,Bongrand P

更新日期：1990-03-01 00:00:00

abstract：:Streptococcus agalactiae (group B Streptococcus or GBS) is a common colonizer of the gastrointestinal and genital tracts and an important cause of invasive infections in newborn infants and in adults with predisposing chronic conditions or advanced age. Attachment to epithelial surfaces at mucosal sites is a critical ...

journal_title：Infection and immunity

authors： Park SE,Jiang S,Wessels MR

更新日期：2012-11-01 00:00:00

abstract：:Attachment and ingestion of Mycobacterium avium subsp. paratuberculosis by two epithelial cell lines were enhanced by soluble fibronectin (FN). Peptide blocking of the FN attachment protein (FAP-P) inhibited the internalization of M. avium subsp. paratuberculosis. Disruption of FAP-P expression significantly reduced a...

journal_title：Infection and immunity

authors： Secott TE,Lin TL,Wu CC

更新日期：2002-05-01 00:00:00

abstract：:Apical membrane antigen 1 (AMA-1) is an invasion-related Plasmodium antigen that is expressed during both intracellular and extracellular asexual stages of the parasite's life cycle, making it an ideal target for induction of humoral and cellular immune responses that can protect against malaria. We show here that whe...

journal_title：Infection and immunity

authors： Bouillet LÉ,Dias MO,Dorigo NA,Moura AD,Russell B,Nosten F,Renia L,Braga EM,Gazzinelli RT,Rodrigues MM,Soares IS,Bruna-Romero O

更新日期：2011-09-01 00:00:00

abstract：:Dendritic cell interactions with pathogenic microbes initiate and direct the development of subsequent adaptive responses. The protozoan pathogen Giardia lamblia infects the mammalian small intestine, leading to nutrient malabsorption and diarrhea but rarely causing inflammation. In order to begin to understand how th...

journal_title：Infection and immunity

authors： Kamda JD,Singer SM

更新日期：2009-02-01 00:00:00

abstract：:Repeated immunizations of CF1 mice with irradiated noninfectious Trypanosoma cruzi trypomastigotes resulted in partial protection against infection with live parasites. It also induced a limited number of antibody species that were reactive in Western blots with trypomastigote but not with epimastigote or amastigote p...

journal_title：Infection and immunity

authors： Zweerink HJ,Weston HD,Andersen OF,Garber SS,Hayes EC

更新日期：1984-12-01 00:00:00

abstract：:Growing Streptococcus gordonii Spp+ phase variants, which have normal levels of glucosyltransferase (GTF) activity, use sucrose to promote their accumulation on surfaces by forming a cohesive bacterium-insoluble glucan polymer mass (BPM). Spp- phase variants, which have lower levels of GTF activity, do not form BPMs a...

journal_title：Infection and immunity

authors： Vickerman MM,Jones GW

更新日期：1992-10-01 00:00:00

abstract：:Vesicular stomatitis virus (VSV) infection of beige (bg/bg) mice induced levels of natural killer cytolytic activity comparable to that of uninfected normal bg/+ controls, but considerably less than natural killer activity in VSV-infected bg/+ mice. In contrast, VSV-infected bg/bg and bg/+ mice had essentially equival...

journal_title：Infection and immunity

authors： McKinnon KP,Hale AH,Ruebush MJ

更新日期：1981-04-01 00:00:00

abstract：:In an attempt to understand the mechanism of serum resistance in Actinobacillus pleuropneumoniae, in the present study we examined various interactions among the bacterial surface constituents, serum antibodies, and complement. Analysis of swine sera revealed the presence of anticapsular antibodies in convalescent-pha...

journal_title：Infection and immunity

authors： Udeze FA,Kadis S

更新日期：1992-09-01 00:00:00

abstract：:In Vibrio cholerae, the transmembrane DNA binding proteins, ToxR and TcpP, activate expression of the regulatory gene toxT in response to specific environmental signals. The resulting enhanced level of ToxT leads to a coordinated increase in the production of a subset of virulence factors, including cholera toxin (CT)...

journal_title：Infection and immunity

authors： Krishnan HH,Ghosh A,Paul K,Chowdhury R

更新日期：2004-07-01 00:00:00

abstract：:We demonstrate that transposon-mediated mutagenesis can be used to construct mutations in the pathogen Brucella abortus. We have used both a plasmid and a bacteriophage to introduce either Tn5 or Tn5 lac into the Brucella chromosome. B. abortus is naturally sensitive to kanamycin. We have selected 22 independent kanam...

journal_title：Infection and immunity

authors： Smith LD,Heffron F

更新日期：1987-11-01 00:00:00

abstract：:Vibrio parahaemolyticus, a gram-negative marine bacterium, is an important pathogen causing food-borne gastroenteritis or septicemia. Recent genome sequencing of the RIMD2210633 strain (a Kanagawa phenomenon-positive clinical isolate of serotype O3:K6) revealed that the strain has two sets of gene clusters that encode...

journal_title：Infection and immunity

authors： Ono T,Park KS,Ueta M,Iida T,Honda T

更新日期：2006-02-01 00:00:00

abstract：:Intestinal epithelial cells (IECs), including secretory goblet cells, form essential physiochemical barriers that separate luminal bacteria from underlying immune cells in the intestinal mucosa. IECs are common targets for enteric bacterial pathogens, with hosts responding to these microbes through innate toll-like re...

journal_title：Infection and immunity

authors： Bhinder G,Stahl M,Sham HP,Crowley SM,Morampudi V,Dalwadi U,Ma C,Jacobson K,Vallance BA

更新日期：2014-09-01 00:00:00

abstract：:The nucleotide sequence of the chromosomal DNA flanking the Actinomyces naeslundii (formerly A. viscosus) T14V type 1 fimbrial structural subunit gene (fimP) was determined. Six open reading frames (ORFs), in the order 5' ORF3, ORF2, ORF1,fimP, ORF4, ORF5, ORF6 3', were identified. ORF1 encoded a protein of 408 amino ...

journal_title：Infection and immunity

authors： Yeung MK,Ragsdale PA

更新日期：1997-07-01 00:00:00

abstract：:A total of 133 Listeria monocytogenes isolates were characterized by ribotyping and allelic analysis of the virulence genes hly, actA, and inlA to uncover linkages between independent phylogenetic and specific virulence markers. PCR-restriction fragment length polymorphisms revealed 8 hly, 11 inl4, and 2 actA alleles....

journal_title：Infection and immunity

authors： Wiedmann M,Bruce JL,Keating C,Johnson AE,McDonough PL,Batt CA

更新日期：1997-07-01 00:00:00

abstract：:Rickettsia rickettsii infection of endothelial cells is manifested in very distinctive changes in cell morphology, consisting of extensive dilatation of the membranes of the endoplasmic reticulum and outer nuclear envelope and blebbing of the plasma membrane, as seen by transmission electron microscopy (D. J. Silverma...

journal_title：Infection and immunity

authors： Eremeeva ME,Silverman DJ

更新日期：1998-05-01 00:00:00

abstract：:Alpha-2,3-sialyltransferase (Lst) is expressed on the outer membrane of Neisseria gonorrhoeae and Neisseria meningitidis and sialylates surface lipooligosaccharide (LOS), facilitating resistance to complement-mediated killing. The enzyme is constitutively expressed from a single gene (lst) and does not undergo antigen...

journal_title：Infection and immunity

authors： Packiam M,Shell DM,Liu SV,Liu YB,McGee DJ,Srivastava R,Seal S,Rest RF

更新日期：2006-05-01 00:00:00

abstract：:The production of type 1 fimbriae in Salmonella enterica serovar Typhimurium is controlled, in part, by three proteins, FimZ, FimY, and FimW. Amino acid sequence analysis indicates that FimZ belongs to the family of bacterial response regulators of two-component systems. In these studies, we have demonstrated that int...

journal_title：Infection and immunity

authors： Zeiner SA,Dwyer BE,Clegg S

更新日期：2013-12-01 00:00:00

abstract：:A number of studies have substantiated the pivotal role of innate defense mechanisms in protection against invasive aspergillosis. However, experiments demonstrating increased resistance to lethal intravenous (i.v.) infection with Aspergillus fumigatus conidia in cortisone-treated or untreated mice preinfected with a ...

journal_title：Infection and immunity

authors： de Repentigny L,Petitbois S,Boushira M,Michaliszyn E,Sénéchal S,Gendron N,Montplaisir S

更新日期：1993-09-01 00:00:00

abstract：:This study was designed to define the lipopolysaccharide (LPS) sensitivity of aged mice in terms of lethality and cytokine production and to determine down-regulating responses of corticosterone and interleukin 10 (IL-10). The 50% lethal doses of LPS in young (6- to 7-week-old) and aged (98- to 102-week-old) mice were...

journal_title：Infection and immunity

authors： Tateda K,Matsumoto T,Miyazaki S,Yamaguchi K

更新日期：1996-03-01 00:00:00

abstract：:Using polystyrene microspheres coated with heparin or heparan sulfate, it was shown that coated microspheres specifically bound eukaryotic cells and were endocytosed by nonprofessional phagocytic cells. Coated microspheres displayed properties of binding to eukaryotic cells that were similar to those of chlamydiae, an...

journal_title：Infection and immunity

authors： Stephens RS,Fawaz FS,Kennedy KA,Koshiyama K,Nichols B,van Ooij C,Engel JN

更新日期：2000-03-01 00:00:00

abstract：:Chemiluminescence of human alveolar macrophages (AM) was evaluated in vitro. Unstimulated AM generated chemiluminescence that remained constant during incubation. Addition of heat-killed Staphylococcus aureus 502A (HKB) or a chemical agent, phorbol myristate acetate, produced high rates of chemiluminescence that were ...

journal_title：Infection and immunity

authors： Beall GD,Repine JE,Hoidal JR,Rasp FL

更新日期：1977-07-01 00:00:00

abstract：:Efficient utilization of heme as an iron (Fe) source by Bordetella avium requires bhuR, an Fe-regulated gene which encodes an outer membrane heme receptor. Upstream of bhuR is a 507-bp open reading frame, hereby designated rhuI (for regulator of heme uptake), which codes for a 19-kDa polypeptide. Whereas the 19-kDa po...

journal_title：Infection and immunity

authors： Kirby AE,Metzger DJ,Murphy ER,Connell TD

更新日期：2001-11-01 00:00:00

abstract：:We examined the immunobiological responses to Histoplasma capsulatum in lungs of gamma interferon (IFN-gamma) knockout mice (GKO mice). Naive GKO mice succumbed by day 9 to intranasal challenge with 2.5 x 10(6) yeasts, whereas all wild-type (WT) mice survived for 45 days. Compared to lungs of WT mice, the lungs of acu...

journal_title：Infection and immunity

authors： Allendoerfer R,Deepe GS Jr

更新日期：1997-07-01 00:00:00

abstract：:MAEBL is a type 1 membrane protein that is implicated in the merozoite invasion of erythrocytes and sporozoite invasion of mosquito salivary glands. This apical organelle protein is structurally similar to the ebl erythrocyte binding proteins, such as EBA-175, except that the tandem ligand domains of MAEBL are similar...

journal_title：Infection and immunity

authors： Preiser P,Rénia L,Singh N,Balu B,Jarra W,Voza T,Kaneko O,Blair P,Torii M,Landau I,Adams JH

更新日期：2004-06-01 00:00:00

abstract：:The two published sequences of the pertussis toxin operon differ in 3 bp in the S1 subunit gene. In this report, we provide evidence that Bordetella pertussis strains are able to produce active pertussis toxin only when they contain one of the two possible nucleotide sequences. ...

journal_title：Infection and immunity

authors： Pizza M,Bugnoli M,Pucci P,Siciliano R,Marino G,Rappuoli R

更新日期：1991-03-01 00:00:00

abstract：:Lymphocytes derived from 72- to 90-day-old fetal piglet thymuses respond in vitro to phytohemagglutinin quantitatively greater than do spleen cell lymphocytes. ...

journal_title：Infection and immunity

authors： Rodey GE,Day N,Holmes-Gray B,Good RA

更新日期：1972-03-01 00:00:00

abstract：:Leptospirosis can activate inflammatory responses through Toll-like receptors (TLRs) and may cause renal tubulointerstitial fibrosis characterized by the accumulation of extracellular matrix (ECM). We have previously demonstrated that Leptospira santorosai serovar Shermani detergent extract stimulates ECM accumulation...

journal_title：Infection and immunity

authors： Tian YC,Hung CC,Li YJ,Chen YC,Chang MY,Yen TH,Hsu HH,Wu MS,Phillips A,Yang CW

更新日期：2011-03-01 00:00:00

abstract：:Chitinases of pathogens have been proposed as potential targets of vaccines or specific inhibitors. We studied the genomic organization, transcript levels, developmental expression, and biological function of chitinases in the rodent filarial nematode Acanthocheilonema viteae, a model organism for human-pathogenic fil...

journal_title：Infection and immunity

authors： Tachu B,Pillai S,Lucius R,Pogonka T

更新日期：2008-01-01 00:00:00

abstract：:We previously showed the requirement of both T cells and gamma interferon (IFN-gamma)-producing non-T cells for the genetic resistance of BALB/c mice to the development of toxoplasmic encephalitis (TE). In order to define the role of IFN-gamma production and the perforin-mediated cytotoxicity of T cells in this resist...

journal_title：Infection and immunity

authors： Wang X,Kang H,Kikuchi T,Suzuki Y

更新日期：2004-08-01 00:00:00