Maternal lung adenocarcinoma metastatic to the scalp of a fetus. Case report.

Abstract:

:Maternal malignancy metastatic to the fetus is a rare event, with most neoplasms being either melanocytic or hematopoietic in origin. This report is the first known case of a maternal lung adenocarcinoma metastatic to a fetus. At 2 months of age, this male infant developed multiple scalp masses that were locally resected but rapidly recurred. The histology of the scalp lesions and that of a biopsy of the mother's tumor were both adenocarcinoma and were remarkably similar in appearance. In situ hybridization of tumor cells from this male infant found many large nuclei with XX signals indicating that the tumor was of maternal origin. This patient is alive, well and free of malignancy 5 years after a wide local resection of the scalp and skin grafting.

journal_name

Pediatr Neurosurg

journal_title

Pediatric neurosurgery

authors

Harpold TL,Wang MY,McComb JG,Monforte HL,Levy ML,Reinisch JF

doi

10.1159/000050384

keywords:

subject

Has Abstract

pub_date

2001-07-01 00:00:00

pages

39-42

issue

1

eissn

1016-2291

issn

1423-0305

pii

50384

journal_volume

35

pub_type

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