Management of holocord pilocytic astrocytomas in children and adolescents: an update.

Abstract:

:Holocord intramedullary low-grade astrocytomas in children and adolescents - involving most or all of the cervical and thoracic spinal cord - are a rare finding. Most of the tumors seem to be pilocytic astrocytomas. Surgical management strategies might not be as clear as in small and circumscribed intramedullary tumors. On the basis of 20 previously published cases and 3 own patients, we summarize and discuss possible treatment options and their risks and benefits. Surgery should be performed soon after establishment of the diagnosis, which per se is often delayed despite a long-standing presence of attributable symptoms or signs in most cases. Following multilevel laminotomy, excellent results can be achieved by electrophysiologically guided microsurgical tumor removal in a single-staged or multistaged approach. The surgical goal is resection as gross total as possible provided intraoperative monitoring indicates preservation of function. Small tumor remnants often remain stable in the due course. In case of unresectable regrowth or recurrence, chemotherapy or radiotherapy are the adjuvant treatment options.

journal_name

Pediatr Neurosurg

journal_title

Pediatric neurosurgery

authors

Ebner FH,Schittenhelm J,Roser F,Scheel-Walter H,Tatagiba M,Schuhmann MU

doi

10.1159/000345593

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

133-40

issue

3

eissn

1016-2291

issn

1423-0305

pii

000345593

journal_volume

48

pub_type

杂志文章,评审
  • Intracranial nasal dermoid sinus cyst associated with colloid cyst of the third ventricle. Case report and new concepts.

    abstract::A case of a 16-year-old male with both a nasal dermoid sinus cyst (NDSC) and a third ventricle colloid cyst is presented. The NDSC was excised via a single-stage combined intracranial-extracranial approach and the third ventricle colloid cyst was resected endoscopically. The pathogenetic theories of NDSC and third ven...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000028862

    authors: Cheng ML,Chang SD,Pang D,Adler JR

    更新日期:1999-10-01 00:00:00

  • Intracranial hypertension after cranial vault decompression for craniosynostosis.

    abstract::A 3-year-old boy with chronic papilledema, bilateral coronal synostosis and Pfeiffer syndrome underwent an orbitofrontal advancement. One month postoperatively, his papilledema had resolved, however, his vision progressively deteriorated over the ensuing 3 months to legal blindness. He had no symptoms or signs of incr...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000120913

    authors: Campbell JW,Albright AL,Losken HW,Biglan AW

    更新日期:1995-01-01 00:00:00

  • Use of bipedicular advancement flaps for intrauterine closure of myeloschisis.

    abstract::Several groups have begun to explore the feasibility and utility of intrauterine closure of myelomeningocele. A subset of these fetuses have defects which fall into the category of myeloschisis, and therefore have inadequate skin to enable primary closure. After considerable discussion, it was decided to utilize biped...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000028898

    authors: Mangels KJ,Tulipan N,Bruner JP,Nickolaus D

    更新日期:2000-01-01 00:00:00

  • Hemihypertrophy and the Chiari I malformation.

    abstract::We report two children with hemihypertrophy and Chiari I malformation (CIM) and review the extant medical literature regarding CIM and overgrowth disorders. We propose that these two entities do not represent a spurious association but rather share a common dysembryology of mesoderm. ...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000069820

    authors: Tubbs RS,Smyth MD,Wellons JC 3rd,Oakes WJ

    更新日期:2003-05-01 00:00:00

  • Endoscopic third ventriculostomy: the Lebanese experience.

    abstract:BACKGROUND:Endoscopic third ventriculostomy (ETV) has gained wide popularity as a first-line treatment for obstructive hydrocephalus (OHC). We have been performing ETV since 1998. We report our experience with this technique in the management of OHC. METHODS:Between 1998 and 2007, we performed 49 ETV procedures in 46 ...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000257525

    authors: Rahme R,Rahme RJ,Hourani R,Moussa R,Nohra G,Okais N,Samaha E,Rizk T

    更新日期:2009-01-01 00:00:00

  • Pineal tumors and associated lesions: the effect of ethnicity on tumor type and treatment.

    abstract::Pineal region lesions consist of a wide variety of rare tumor types, including deep midline cysts, intrinsic pineal tumors, germ cell tumors and vascular lesions. Advances in microsurgical, endoscopic and stereotactic techniques have helped to lower morbidity and mortality in the care of patients harboring these lesio...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1159/000070415

    authors: Knierim DS,Yamada S

    更新日期:2003-06-01 00:00:00

  • Spontaneous thrombosis of vein of Galen aneurysmal malformation.

    abstract::Two cases of aneurysmal malformations of the vein of Galen (AVG) with spontaneous thrombosis are reported. Angiogram and MRI before thrombosis demonstrated AVGs with slow arteriovenous shunts and associated stagnation of contrast in the venous sac secondary to severe outflow restriction. Based on these findings, one p...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1159/000028828

    authors: Nikas DC,Proctor MR,Scott RM

    更新日期:1999-07-01 00:00:00

  • Meckel-Gruber Syndrome: A Case Who Lived for 5 Months.

    abstract::The Meckel-Gruber syndrome is a rare, congenital, and lethal malformation characterized by typical manifestations such as encephalocele, polycystic kidneys, and polydactyly. Herein, we present a case of a patient with the typical triad as well as facial, ocular, liver, and genital abnormalities who lived for almost 5 ...

    journal_title:Pediatric neurosurgery

    pub_type:

    doi:10.1159/000500766

    authors: Aydin Ozturk P,Asena M,Katar S,Ozturk U

    更新日期:2019-01-01 00:00:00

  • Giant Cavernous Malformations in Childhood: A Case Report and Review of the Literature.

    abstract::Cavernous malformations (CMs) of the central nervous system are benign, angiographically occult vascular lesions and are diagnosed by magnetic resonance imaging techniques. Giant CMs do not differ from smaller-sized CMs in their clinical, surgical or histopathological presentation but may be radiologically different. ...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1159/000447407

    authors: Ozsoy KM,Oktay K,Gezercan Y,Cetinalp NE,Olguner SK,Erman T

    更新日期:2017-01-01 00:00:00

  • Chiasmal cavernoma: a rare cause of acute visual loss improved by prompt surgery.

    abstract::We report a 16-year-old healthy boy who presented with sudden loss of vision in both eyes, accompanied by a mild headache. Magnetic resonance imaging showed a chiasmal apoplexy. An urgent craniotomy revealed a cavernous malformation of the chiasm, which was evacuated. There was a subsequent dramatic improvement in bil...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000149911

    authors: Newman H,Nevo M,Constantini S,Maimon S,Kesler A

    更新日期:2008-01-01 00:00:00

  • Transient Horizontal Gaze Palsy in a One-Month-Old Boy after a Fall.

    abstract::A 1-month-old boy was evaluated after a fall from a height of 3 feet and found to have right parietal skull fracture as well as right and left frontal traumatic hemorrhage. Ten days after the injury, he represented with a persistent left gaze preference. Further workup including MRI and EEG determined that this findin...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000441680

    authors: Bourne SK,Duhaime AC

    更新日期:2016-01-01 00:00:00

  • Extradural hematomas in children.

    abstract::The authors studied 58 patients, under 12 years of age, admitted to the Emergency Room of the Sao Paulo University Hospital between September 1987 and November 1991 with the diagnosis of traumatic extradural hematoma. Emphasis was given to the etiology of injury, the time interval from head injury to emergency room ev...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000120814

    authors: dos Santos AL,Plese JP,Ciquini Júnior O,Shu EB,Manreza LA,Marino Júnior R

    更新日期:1994-01-01 00:00:00

  • A case of cerebellar capillary hemangioma with multiple cysts.

    abstract::Intracranial capillary hemangiomas are very rare, though several spinal capillary hemangiomas have recently been reported. We report here a case of intracranial capillary hemangioma with multiple cysts and review the current literature of similar cases. A 4-month-old girl was referred to our hospital for treatment of ...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000138375

    authors: Uyama A,Kawamura A,Akiyama H,Nakamizo S,Yamamoto K,Nagashima T,Uetani T,Takeda H,Yoshida M

    更新日期:2008-01-01 00:00:00

  • Selective functional posterior rhizotomy for treatment of spastic cerebral palsy in children. Review of 50 consecutive cases.

    abstract::Fifty consecutive children are described with spastic cerebral palsy treated with selective functional lumbar and sacral rhizotomy and followed for a minimum of 6 months. In all patients, spasticity improved postoperatively, but this was not necessarily accompanied by a functional improvement. Eighteen children who co...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000120639

    authors: Steinbok P,Reiner A,Beauchamp RD,Cochrane DD,Keyes R

    更新日期:1992-01-01 00:00:00

  • Update on Endoscopic Third Ventriculostomy in Children.

    abstract::Endoscopic third ventriculostomy (ETV) provides a physiological restoration of cerebrospinal fluid and a shunt-free option for hydrocephalus children. Continuous developments in techniques and instruments have improved ETV as the first-line treatment. This paper focuses on the recent advances in surgical techniques, i...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1159/000491638

    authors: Feng Z,Li Q,Gu J,Shen W

    更新日期:2018-01-01 00:00:00

  • Prognostic significance of molecular genetic markers in childhood brain tumors.

    abstract::Molecular genetic analysis of several common cancers has yielded information concerning their etiology and prognosis. Restriction fragment length polymorphism (RFLP) studies showing consistent loss of specific DNA sequences in tumor tissue have identified genes, known as tumor suppressors, associated with the etiology...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1159/000120605

    authors: Cogen PH

    更新日期:1991-01-01 00:00:00

  • Experimental split cord malformations.

    abstract:OBJECTIVE:To induce experimental split cord malformations (SCMs) produced through the surgical induction of a dorsal midline fistula. METHODS:In addition, the theory of embryogenesis of SCMs was verified by examining the developmental process of this experimentally induced anomaly. In Cynopus pyrrhogaster (amphibian) ...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000058425

    authors: Emura T,Asashima M,Furue M,Hashizume K

    更新日期:2002-05-01 00:00:00

  • Focal cortical dysplasia with glioproliferative changes causing seizures: report of 3 cases.

    abstract::In contrast to neoplasia, lesions of focal cerebral dysplasia are thought to be completed developmental processes of abnormal neuronal migration. We present three children with seizures resulting from brain lesions which pathologically demonstrate regions of both clearcut focal cortical dysplasia and also hypercellula...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000028662

    authors: Madsen JR,Vallat AV,Poussaint TY,Scott RM,De Girolami U,Anthony DC

    更新日期:1998-05-01 00:00:00

  • The first description of a device for repeated external ventricular drainage in the treatment of congenital hydrocephalus, invented in 1744 by Claude-Nicolas Le Cat.

    abstract::An 18th century report of a device for repeated extracranial drainage of cerebrospinal fluid in the treatment of congenital hydrocephalus is reviewed. On 15th October 1744, the French surgeon Claude-Nicolas Le Cat (1700-1768) introduced a specially invented canula into the lateral ventricle of a newborn boy with hydro...

    journal_title:Pediatric neurosurgery

    pub_type: 传,历史文章,杂志文章

    doi:10.1159/000070872

    authors: Kompanje EJ,Delwel EJ

    更新日期:2003-07-01 00:00:00

  • Regressing intracranial carotid occlusions in childhood.

    abstract::Though detected with increasing frequency, intracranial carotid artery dissection remains less common in infancy. We report on 3 otherwise healthy children aged 8, 12 and 15 years who presented with focal headache and stroke secondary to intracranial carotid occlusive disease consistent with arterial dissection. In 2 ...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000120844

    authors: Pozzati E,Galassi E,Godano U,Cordella L

    更新日期:1994-01-01 00:00:00

  • Robot-assisted endoscopic intrauterine myelomeningocele repair: a feasibility study.

    abstract:BACKGROUND:Animal experiments have suggested that the intrauterine environment causes secondary injury to the congenitally dysplastic spinal cord. This in turn suggests that early closure of the myelomeningocele sac might prevent secondary injury and therefore improve neurologic outcome. This study was designed to exam...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000048358

    authors: Aaronson OS,Tulipan NB,Cywes R,Sundell HW,Davis GH,Bruner JP,Richards WO

    更新日期:2002-02-01 00:00:00

  • Conventional and diffusion-weighted magnetic resonance imaging findings in a pediatric patient with a posterior fossa brain tumor and papilledema.

    abstract::We present a case report of a 21-month-old female patient to highlight magnetic resonance (MR) imaging findings associated with papilledema in a pediatric patient with an intracranial tumor. The MR findings included optic disc elevation, dilated perioptic subarachnoid spaces, optic nerve tortuosity and restricted diff...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000270156

    authors: Pakzad-Vaezi K,Cochrane D,Sargent M,Singhal A

    更新日期:2009-01-01 00:00:00

  • Are dermoid and epidermoid tumors preventable complications of myelomeningocele repair?

    abstract::Dermoids and epidermoids found at reoperation for tethered cord following myelomeningocele repair have been attributed to inadequate excision of cutaneous elements and 'implantation' in the repair site. This study reviews the pathological findings in excised placodes from fresh myelomeningoceles and specimens from tet...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1159/000120780

    authors: Storrs BB

    更新日期:1994-01-01 00:00:00

  • Delayed diagnosis of neurological bladder following spinal cord injury without radiological abnormality.

    abstract::Spinal cord injuries are a well-known cause of neurological bladder and a well-known complication of high-velocity trauma. They can, however, be difficult to diagnose in young children, in whom the absence of initial neurological symptoms and normality of the radiological workup can be falsely reassuring. Management o...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000360402

    authors: Abbo O,Mouttalib S,L'Kaissi M,Sauvat F,Accadbled F,Harper L

    更新日期:2013-01-01 00:00:00

  • Tethered cord associated with anorectal malformation.

    abstract::Ten children with a tethered cord and also an anorectal malformation are reported in this document. The anorectal malformations comprised 5 vesicointestinal fissures, 2 cloacal exstrophies, 2 rectovesical fistulas and 1 rectobulbar fistula. All of the patients underwent colostomy in advance of surgery for untethering ...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000068048

    authors: Morimoto K,Takemoto O,Wakayama A

    更新日期:2003-02-01 00:00:00

  • Treatment of craniosynostosis by distraction osteogenesis.

    abstract:PURPOSE:Craniosynostosis patients treated with one-stage cranioplasty often have bleeding from the dura mater, fluid collection in the extradural space, and poor wound healing due to skin overstretching. To avoid these complications, we began using distraction osteogenesis. To determine the advantages and disadvantages...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000094064

    authors: Akai T,Iizuka H,Kawakami S

    更新日期:2006-01-01 00:00:00

  • Pediatric hemifacial spasm: the efficacy of microvascular decompression.

    abstract::Hemifacial spasm (HFS), generally a disease of the elderly, is caused by vascular compression of the seventh nerve. Vascular compression is thought to result from atherosclerotic changes within the vessels of the posterior fossa, and therefore rarely presents in childhood. Here we describe our experience with 12 patie...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000121260

    authors: Levy EI,Resnick DK,Jannetta PJ,Lovely T,Bissonette DJ

    更新日期:1997-11-01 00:00:00

  • Contemporary chemotherapy issues for children with brainstem gliomas.

    abstract::Radiotherapy has remained the mainstay of treatment for children with intrinsic, diffuse pontine tumors in spite of over 20 years of clinical trials attempting to validate the additional role of chemotherapy. Conventional phase II clinical trials conducted in patients with recurrent or progressive brainstem gliomas us...

    journal_title:Pediatric neurosurgery

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1159/000121024

    authors: Allen JC,Siffert J

    更新日期:1996-01-01 00:00:00

  • Inflicted traumatic brain injury: relationship of developmental outcome to severity of injury.

    abstract::Inflicted traumatic brain injury (TBI) is a frequent consequence of physical child abuse in infants and children. Twenty-eight children who were 2-42 months of age when hospitalized for moderate to severe TBI were enrolled in a prospective, longitudinal study of neurobehavioral outcome following acquired brain injury....

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000028872

    authors: Ewing-Cobbs L,Prasad M,Kramer L,Landry S

    更新日期:1999-11-01 00:00:00

  • Tuberculoma of the Cavernous Sinus and Meckel's Cave in a Child.

    abstract::Tuberculous infection of the cavernous sinus and Meckel's cave is extremely rare. In this report, we describe a patient with tuberculoma of the cavernous sinus and Meckel's cave, extending to the petrous apex. The patient underwent microsurgical excision of the lesion and antitubercular chemotherapy resulting in a goo...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000369030

    authors: Kumar VR,Madhugiri VS,Verma SK,Barathi SD,Yadav AK,Bidkar P

    更新日期:2013-01-01 00:00:00