Novalis radiosurgery of optic gliomas in children: preliminary report.

Abstract:

AIM:To evaluate the effectiveness of Novalis radiosurgery (RS) in children with optic gliomas. METHODS:Four pediatric patients (1 male and 3 female) were treated for optic gliomas with Novalis RS in our institution between February 2002 and July 2002. Their mean age was 12 (range 5-16) years at presentation for Novalis RS. The mean target dose was 44 (range 41-45) Gy, with a mean fractionation dose of 1.58 (range 1.5-1.65) Gy. Follow-up included magnetic resonance imaging and ophthalmologic and endocrine examinations. RESULTS:The mean follow-up period was 54 (range 50-58) months. During the follow-up period, all patients were alive. Local control of the tumor was obtained in all patients. None of the patients showed clinically relevant morbidity, especially endocrine dysfunction. CONCLUSIONS:Novalis RS may be an excellent treatment method for optic gliomas in children. However, long-term follow-up is required for further evaluation of efficacy and potential side effects.

journal_name

Pediatr Neurosurg

journal_title

Pediatric neurosurgery

authors

Han SR,Yoon SW,Yee GT,Choi CY,Sohn MJ,Lee DJ,Whang CJ

doi

10.1159/000103305

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

251-7

issue

4

eissn

1016-2291

issn

1423-0305

pii

000103305

journal_volume

43

pub_type

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