Abstract:
AIM:To evaluate the effectiveness of Novalis radiosurgery (RS) in children with optic gliomas. METHODS:Four pediatric patients (1 male and 3 female) were treated for optic gliomas with Novalis RS in our institution between February 2002 and July 2002. Their mean age was 12 (range 5-16) years at presentation for Novalis RS. The mean target dose was 44 (range 41-45) Gy, with a mean fractionation dose of 1.58 (range 1.5-1.65) Gy. Follow-up included magnetic resonance imaging and ophthalmologic and endocrine examinations. RESULTS:The mean follow-up period was 54 (range 50-58) months. During the follow-up period, all patients were alive. Local control of the tumor was obtained in all patients. None of the patients showed clinically relevant morbidity, especially endocrine dysfunction. CONCLUSIONS:Novalis RS may be an excellent treatment method for optic gliomas in children. However, long-term follow-up is required for further evaluation of efficacy and potential side effects.
journal_name
Pediatr Neurosurgjournal_title
Pediatric neurosurgeryauthors
Han SR,Yoon SW,Yee GT,Choi CY,Sohn MJ,Lee DJ,Whang CJdoi
10.1159/000103305subject
Has Abstractpub_date
2007-01-01 00:00:00pages
251-7issue
4eissn
1016-2291issn
1423-0305pii
000103305journal_volume
43pub_type
杂志文章abstract:OBJECTIVE/AIM:Hydrocephalus is defined as an incapacitating neurological disorder characterized by ventricular enlargement in children, but the effects of melatonin on this hydrocephalus have not yet been fully elucidated. In the present experiment, we attempted to investigate the effects of exogenous melatonin adminis...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000488497
更新日期:2018-01-01 00:00:00
abstract::We report a case of a 7-year-old child with a cranial deformity secondary to a craniotomy for an intracranial hematoma. He suffered from an acute epidural hematoma with a lineal fracture of the right temporal bone following a severe head injury. A large question mark-shaped skin flap with the periosteum and temporal m...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000452804
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:We review our experience of endoscopic third ventriculocisternostomy (ETV) in children with hydrocephalus from central nervous system (CNS) infection or intraventricular hemorrhage to better elucidate success rates and predictors of success in these children. METHODS:We performed a retrospective review of 12...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000072871
更新日期:2003-11-01 00:00:00
abstract:INTRODUCTION:An international multicenter randomized trial comparing standard pressure differential valves, Orbis Sigma valves and PS Medical Delta valves, for children with newly diagnosed hydrocephalus failed to show a difference in the time to first shunt failure (power 80%). In order to avoid observer bias, the pri...
journal_title:Pediatric neurosurgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000028764
更新日期:1999-02-01 00:00:00
abstract:BACKGROUND/AIMS:Central nervous system germ cell tumors (CNS-GCTs) are relatively rare. While their incidence was thought to be higher in East Asia than the USA, recent evidence suggests the difference between Japan and the USA is not statistically significant. The aim of this study was to determine the rate of pediatr...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,多中心研究
doi:10.1159/000358806
更新日期:2013-01-01 00:00:00
abstract::This is a report of a prenatal sonographic diagnosis of a lateral ventricle choroid plexus papilloma in an in vitro fertilization (IVF)-induced pregnancy of a 40-year-old woman. The baby was delivered at 35 weeks of gestation and surgery was performed 5 days later with a good outcome. Several cases of malignancies ass...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000066210
更新日期:2002-11-01 00:00:00
abstract::Prepontine arachnoid cysts are rare developmental anomalies that occur almost exclusively in children. The symptomatic child typically suffers from hydrocephalus, visual impairment, endocrine dysfunction and/or cranial neuropathies. Some cysts, however, are discovered incidentally upon prenatal or postnatal imaging fo...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000064394
更新日期:2002-09-01 00:00:00
abstract::A three-year old girl who initially presented at 16 months with epistaxis from an anterior skull base vascular anomaly returned with near-fatal epistaxis despite embolization of the internal maxillary artery at the time of initial presentation. Repeat angiography demonstrated blood supply to the vascular lesion coming...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000050432
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:As prior studies analysed predictive factors for various post-laminectomy spinal deformities in mixed spinal regions, age groups or pathologies, their validity and conclusions were unclear. The objective of this study was to determine predictive factors for worsened cervical or thoracic spinal sagi...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000050444
更新日期:2001-12-01 00:00:00
abstract::For over 60 years congenital kyphotic deformities of the spine have been categorized into two distinct groups, depending on the developmental defect. Those arising from a failure of formation of the vertebral bodies were classified as type 1, while those arising from a failure of segmentation were referred to as type ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121178
更新日期:1997-03-01 00:00:00
abstract::We report two children with hemihypertrophy and Chiari I malformation (CIM) and review the extant medical literature regarding CIM and overgrowth disorders. We propose that these two entities do not represent a spurious association but rather share a common dysembryology of mesoderm. ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000069820
更新日期:2003-05-01 00:00:00
abstract::Although extra-axial hematomas are a well-known complication of ventricular shunting, epidural hematomas are uncommon in this setting. We report an unusual case of multiple epidural hematomas in a patient with hydrocephalus treated by ventriculoperitoneal shunt. The patient became symptomatic 5 days after shunting and...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120704
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND:Interictal 18F-fluorodeoxyglucose-positron emission topography (FDG-PET) hypometabolism is routinely used in the presurgical workup of children with medically intractable epilepsy (MIE). FDG-PET hypermetabolism, however, is rarely seen, and the significance of this finding in the epilepsy workup is not well ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000487088
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Histiocytoses are rare diseases affecting mainly children and can occur in any organ of the body. They are divided into Langerhans type and non-Langerhans type. Langerhans cell histiocytosis (LCH) mainly affects skin, bones, and lymph nodes but can also affect the hematopoietic system. Bone lesions can be cr...
journal_title:Pediatric neurosurgery
pub_type:
doi:10.1159/000508940
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:There are currently no clear guidelines for the management and radiological monitoring of pediatric patients with epidural hematomas (EDH). We aim to compare clinical and radiographic characteristics of pediatric EDH patients managed with observation alone versus surgical evacuation and to describe results o...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000363143
更新日期:2013-01-01 00:00:00
abstract::Sylvian arachnoid cysts pose considerable management dilemmas. Surgical options include cyst fenestration, either endoscopically or microsurgically, and cysto-peritoneal shunt. One of the rare complications after rapid decompression of the arachnoid cysts is haemorrhage in the surrounding brain as well as in remote ar...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000452224
更新日期:2017-01-01 00:00:00
abstract::Meningeal melanocytoma is an infrequent neoplasm of the central nervous system (CNS), especially in childhood and infancy. It was first described as an entity different from pigmented meningiomas and schwannomas in 1972, and few cases have been published so far. In this article, a 5-month-old male patient with meninge...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000028945
更新日期:2000-05-01 00:00:00
abstract::A needle for intravenous fluid administration in a newborn was accidentally placed in the sagittal sinus and resulted in dural sinus air embolism. CT findings are described and the risks for venous air embolism are discussed. ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120606
更新日期:1991-01-01 00:00:00
abstract:UNLABELLED:Since 1990, 110 retrograde ventriculo-sinus (RVS) shunts were implanted; 98 patients (89.1%) benefited - 1 of them (0.9%) after shunt revision. The manifestations of high intra cranial pressure (ICP) disappeared, there were no problems related to improper cerebrospinal fluid (CSF) drainage, and the transcran...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000088733
更新日期:2005-11-01 00:00:00
abstract::Primary spinal primitive neuroectodermal tumor (PSPNET) is extremely rare and only 25 cases have been reported in the world literature so far. Three patients of 8, 9 and 18 years of age, who presented with variable grades of neurological deficit were diagnosed as having a dorsal intramedullary lesion, a holocord lesio...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000097517
更新日期:2007-01-01 00:00:00
abstract::A 3-month-old female patient presented with a meningomyelocele at the lumber region associated with congenital hydrocephalus. She underwent ventriculoperitoneal (V-P) shunt surgery using the Sophy system. The shunt system was replaced due to a malformation. Following replacement, the patient presented with cerebrospin...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028752
更新日期:1999-01-01 00:00:00
abstract::Focal intracranial infections due to Salmonella are rare. So far, around 80 cases have been reported in the world literature. The authors present their experience of 6 cases of intracranial Salmonella infections, mainly subdural empyema in 5 and effusion in 1. In 1 case, subdural empyema was bilateral, and in another ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000048342
更新日期:2002-01-01 00:00:00
abstract::An 18th century report of a device for repeated extracranial drainage of cerebrospinal fluid in the treatment of congenital hydrocephalus is reviewed. On 15th October 1744, the French surgeon Claude-Nicolas Le Cat (1700-1768) introduced a specially invented canula into the lateral ventricle of a newborn boy with hydro...
journal_title:Pediatric neurosurgery
pub_type: 传,历史文章,杂志文章
doi:10.1159/000070872
更新日期:2003-07-01 00:00:00
abstract::Blunt carotid injury (BCI) is an uncommon yet potentially devastating entity which has received little attention in the pediatric literature. In an attempt to better characterize pediatric BCI, a review of the National Pediatric Trauma Registry was performed. Records were obtained from all children diagnosed with inte...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000028804
更新日期:1999-05-01 00:00:00
abstract::In contrast to neoplasia, lesions of focal cerebral dysplasia are thought to be completed developmental processes of abnormal neuronal migration. We present three children with seizures resulting from brain lesions which pathologically demonstrate regions of both clearcut focal cortical dysplasia and also hypercellula...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028662
更新日期:1998-05-01 00:00:00
abstract::Osteoblastomas and aneurysmal bone cysts are uncommon benign tumors of the spine. Their presentation can vary between diffuse pain, restriction of neck movements, torticollis, radiculopathy, and myelopathy. Complete excision is the best treatment to achieve a cure, but recurrence is not uncommon. A combination of the ...
journal_title:Pediatric neurosurgery
pub_type:
doi:10.1159/000495065
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:Nondysraphic intramedullary lipomas of the spinal cord are rare lesions. They are most commonly seen in the second or third decade of life. Their occurrence in the pediatric age group is even rarer. CASE REPORT:The authors describe a 14-month-old child who presented with delayed motor milestones involving...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000334258
更新日期:2011-01-01 00:00:00
abstract::It is essential that various factors be considered when determining the differential diagnosis of congenital scalp lesions, including lesion size, appearance, intracranial extension, underlying medical condition and the embryological germ layer involved. We present the case of a newborn diagnosed as having a sebaceous...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000113118
更新日期:2008-01-01 00:00:00
abstract::Intracranial and intraspinal ependymomas are uncommon tumors of the central nervous system. These tumors have a variety of imaging characteristics, some of which are fairly specific for ependymoma. We discuss the MRI features of ependymomas for each of the typical locations within the neuraxis, and provide MR imaging ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028630
更新日期:1998-02-01 00:00:00
abstract::Ten children with a tethered cord and also an anorectal malformation are reported in this document. The anorectal malformations comprised 5 vesicointestinal fissures, 2 cloacal exstrophies, 2 rectovesical fistulas and 1 rectobulbar fistula. All of the patients underwent colostomy in advance of surgery for untethering ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000068048
更新日期:2003-02-01 00:00:00