Biliary lipid output during three meals and an overnight fast. II. Effect of chenodeoxycholic acid treatment in gallstone subjects.

abstract：BACKGROUND AND AIM:The lymphatic network plays a major role in maintaining tissue fluid homoeostasis. Therefore several pathological conditions associated with oedema formation result in deficient lymphatic function. However, the role of the lymphatic system in the pathogenesis of ascites and oedema formation in cirrho...

journal_title：Gut

authors： Ribera J,Pauta M,Melgar-Lesmes P,Tugues S,Fernández-Varo G,Held KF,Soria G,Tudela R,Planas AM,Fernández-Hernando C,Arroyo V,Jiménez W,Morales-Ruiz M

更新日期：2013-01-01 00:00:00

abstract：:Large numbers of cells are shed from small intestinal mucosa but they are so rapidly destroyed that there is little direct information about their morphological types. Material obtained by washing the human and rat small intestine was immediately processed and examined by light and electron microscopy. Small intestina...

journal_title：Gut

authors： Pink IJ,Croft DN,Creamer B

更新日期：1970-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The authors have previously isolated a putative oncogene, eukaryotic initiation factor 5A2 (EIF5A2) from 3q26. In this study, EIF5A2 was characterised for its role in colorectal carcinoma (CRC) aggressiveness and underlying molecular mechanisms. METHODS:The expression dynamics of EIF5A2 were examin...

journal_title：Gut

authors： Zhu W,Cai MY,Tong ZT,Dong SS,Mai SJ,Liao YJ,Bian XW,Lin MC,Kung HF,Zeng YX,Guan XY,Xie D

更新日期：2012-04-01 00:00:00

abstract：:Oral disodium cromoglycate (200 mg qds) has been tested in 26 patients with ulcerative colitis that was resistant to medical treatment. In a double-blind crossover trial disodium cromoglycate and placebo were added to conventional treatment in random order, each for four weeks. There was no significant difference in t...

journal_title：Gut

authors： Buckell NA,Gould SR,Day DW,Lennard-Jones JE,Edwards AM

更新日期：1978-12-01 00:00:00

abstract：:Synchronous cancers of the oesophagus and stomach diagnosed in a patient showing pronounced leucocytosis were examined for production of granulocyte colony stimulating factor (G-CSF) and expression of G-CSF receptor. Whereas enzyme immunoassay of tissue extracts showed that the oesophageal carcinoma produced G-CSF, th...

journal_title：Gut

authors： Ichiishi E,Yoshikawa T,Kogawa T,Yoshida N,Kondo M

更新日期：2000-03-01 00:00:00

abstract：:The HGT-1 gastric cancer cell line was used to determine the actions of protein kinase C on the stimulation of adenylate cyclase by the human histamine H2 receptor, and the receptors for gastric inhibitory polypeptide and truncated glucagon like peptide 1 (TGLP-1). Suspensions of HGT-1 cells were preincubated with the...

journal_title：Gut

authors： McKenna P,Williams JM,Gespach CP,Hanson PJ

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:Osteopontin (OPN) has been found to be valuable in diagnosis and predicting the prognosis of a variety of malignancies. The aims of the present study are to evaluate the usefulness of plasma OPN level for predicting gastric cancer development, invasion and survival. PATIENTS AND METHODS:One hundred and thirt...

journal_title：Gut

authors： Wu CY,Wu MS,Chiang EP,Wu CC,Chen YJ,Chen CJ,Chi NH,Chen GH,Lin JT

更新日期：2007-06-01 00:00:00

abstract：:With oral and intravenous doses of metoclopramide there was no constant effect on the gastric emptying of test meals of glucose or sodium citrate, nor was secretion of acid by the stomach in response to test meals of glucose or sodium citrate affected. Apomorphine, in subnauseous doses (0.25 mg intravenously) slowed t...

journal_title：Gut

authors： Ramsbottom N,Hunt JN

更新日期：1970-12-01 00:00:00

abstract：OBJECTIVE:To present comparative data about the performance of colorectal cancer (CRC) screening programmes in the European Union Member States (EU MSs). DESIGN:Cross-sectional study. We analysed key performance indicators-participation rate, positivity rate (PR), detection rate (DR) and positive predictive value for ...

journal_title：Gut

authors： Senore C,Basu P,Anttila A,Ponti A,Tomatis M,Vale DB,Ronco G,Soerjomataram I,Primic-Žakelj M,Riggi E,Dillner J,Elfström MK,Lönnberg S,Sankaranarayanan R,Segnan N

更新日期：2019-07-01 00:00:00

abstract：:Spirits from areas of high and low incidence of cancer of the oesophagus were examined for volatile nitrosamines using a chemiluminescent detector. No nitrosamines were found, the detection limit being 0.001 microng/ml. ...

journal_title：Gut

authors： Gough TA

更新日期：1977-04-01 00:00:00

abstract：:THE SMOOTH MUSCLE SPHINCTERIC ACTIVITY OF THE ANUS IN CATS IS BASED ON TWO DISTINCT MECHANISMS: a typical anal component, characterized by anal slow pressure waves not related to spike potentials in the internal anal sphincter, and an intestinal-like pressure component related to spiking activity in the internal sphin...

journal_title：Gut

authors： Kerremans R,Penninckx F

更新日期：1970-08-01 00:00:00

abstract：:Because of the increasing use of immunosuppressive and biological drugs, the occurrence of opportunistic infections has become a key safety issue for patients with inflammatory bowel disease (IBD). Consequently, improvement of healthcare workers' knowledge of this domain is urgent. In this review, the preventive measu...

journal_title：Gut

authors： Viget N,Vernier-Massouille G,Salmon-Ceron D,Yazdanpanah Y,Colombel JF

更新日期：2008-04-01 00:00:00

abstract：:The effects of different bile salts on the absorption of fluid, electrolytes, and monosaccharides have been investigated in the rat small intestine in vivo. In the jejunum, deoxycholate (1 mM) impaired absorption of water and potassium, but not of sodium or glucose; at higher concentrations (2.5 and 5 mM) secretion of...

journal_title：Gut

authors： Harries JT,Sladen GE

更新日期：1972-08-01 00:00:00

abstract：CLINICAL PRESENTATION:A 28-year-old woman presented with a 3-year history of chronic watery diarrhoea along with abdominal pain and bloating, which could mostly be alleviated after defecation. Her symptom of diarrhoea, at least three times a day, could be relieved by neither probiotics nor antidiarrhoeal agents. She ha...

journal_title：Gut

authors： Zhou CB,Lu H,Chen YX,Fang JY

更新日期：2019-03-01 00:00:00

abstract：:p53 mutations are a common genetic finding in hepatocellular carcinoma from areas of high aflatoxin exposure. Recent small studies have shown that p53 gene mutations may be less common in areas with a low prevalence of hepatocellular carcinoma such as Great Britain. The protein product of mutant p53 can be detected im...

journal_title：Gut

authors： Collier JD,Carpenter M,Burt AD,Bassendine MF

更新日期：1994-01-01 00:00:00

abstract：:Proximal diversion has commonly been used for severe perianal Crohn's disease in an attempt to relieve local symptoms, whether the primary intestinal disease is in the colon or small bowel. Two patients are presented in whom diversion led to severe symptomatic disease in the previously normal defunctioned bowel. In ea...

journal_title：Gut

authors： Williamson ME,Hughes LE

更新日期：1994-08-01 00:00:00

abstract：:Some patients with diarrhoea predominant irritable bowel syndrome have increased rectal sensitivity. It is uncertain, however, whether the diarrhoea is a consequence of the rectal sensitivity or if it is sensitising the rectum in some way. The aim of this study was to assess whether inducing diarrhoea in normal health...

journal_title：Gut

authors： Houghton LA,Wych J,Whorwell PJ

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Pancreatic cancer is among the most dismal of human malignancies. Current therapeutic strategies are virtually ineffective in controlling advanced, metastatic disease. Recent evidence suggests that the Hedgehog signalling pathway is aberrantly reactivated in the majority of pancreatic cancers, and t...

journal_title：Gut

authors： Feldmann G,Habbe N,Dhara S,Bisht S,Alvarez H,Fendrich V,Beaty R,Mullendore M,Karikari C,Bardeesy N,Ouellette MM,Yu W,Maitra A

更新日期：2008-10-01 00:00:00

abstract：INTRODUCTION:In pancreatic cancer, preoperative biliary drainage (PBD) increases complications compared with surgery without PBD, demonstrated by a recent randomised controlled trial (RCT). This outcome might be related to the plastic endoprosthesis used. Metal stents may reduce the PBD-related complications risk. MET...

journal_title：Gut

authors： Tol JA,van Hooft JE,Timmer R,Kubben FJ,van der Harst E,de Hingh IH,Vleggaar FP,Molenaar IQ,Keulemans YC,Boerma D,Bruno MJ,Schoon EJ,van der Gaag NA,Besselink MG,Fockens P,van Gulik TM,Rauws EA,Busch OR,Gouma DJ

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Although peroxisome proliferator activated receptor gamma (PPARgamma) agonists have been implicated in differentiation and growth inhibition of cancer cells, the potential therapeutic and chemopreventive effects on gastric cancer are poorly defined. We examined the in vitro and in vivo effects of PP...

journal_title：Gut

authors： Leung WK,Bai AH,Chan VY,Yu J,Chan MW,To KF,Wu JR,Chan KK,Fu YG,Chan FK,Sung JJ

更新日期：2004-03-01 00:00:00

abstract：:Using 24 hour pH monitoring as a reference standard, the usefulness of the acid perfusion (AP) test in predicting gastro-oesophageal reflux disease (GORD) was assessed in 71 non-cardiac chest pain (NCCP) patients and 23 endoscopic oesophagitis patients. Of the 71 NCCP patients, 35 had a positive AP test (of whom 20 ha...

journal_title：Gut

authors： Hewson EG,Sinclair JW,Dalton CB,Wu WC,Castell DO,Richter JE

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:Lynch syndrome is caused by germline mutations in DNA mismatch repair genes leading to microsatellite instability (MSI) and colorectal cancer. Mesalazine, commonly used for the treatment of UC, reduces MSI in vitro. Here, we tested natural compounds for such activity and applied mesalazine and thymoquinone in...

journal_title：Gut

authors： Kortüm B,Campregher C,Lang M,Khare V,Pinter M,Evstatiev R,Schmid G,Mittlböck M,Scharl T,Kucherlapati MH,Edelmann W,Gasche C

更新日期：2015-12-01 00:00:00

abstract：AIM:Recurrent bleeding after initial haemostasis is an important factor that directly relates to the outcome in the management of peptic ulcer bleeding. Conflicting reports have been published concerning the effectiveness of scheduled second therapeutic endoscopy on ulcer rebleeding. We investigate the use of scheduled...

journal_title：Gut

authors： Chiu PW,Lam CY,Lee SW,Kwong KH,Lam SH,Lee DT,Kwok SP

更新日期：2003-10-01 00:00:00

abstract：:A chronic colitis has been induced in rabbits having many of the histological features of human ulcerative colitis. Animals were first immunised with the common enterobacterial antigen of Kunin and haemagglutinating antibodies demonstrated in high titre. An immune complex colitis was then established by the injection ...

journal_title：Gut

authors： Mee AS,McLaughlin JE,Hodgson HJ,Jewell DP

更新日期：1979-01-01 00:00:00

abstract：:A study of HLA-DR antigen in 75 patients with primary biliary cirrhosis has been carried out in order to test the hypothesis that genetic factors related to genes controlling immune responses might be important in the pathogenesis of primary biliary cirrhosis. The frequencies of HLA-DR locus antigens was not significa...

journal_title：Gut

authors： Bassendine MF,Dewar PJ,James OF

更新日期：1985-06-01 00:00:00

abstract：:Multinucleated giant cells are an important feature of the granulomatous reaction in Crohn's disease (CD) but their cellular origin is poorly understood. The aim of this study was to discover if intestinal macrophages are capable of generating multinucleated giant cells in vitro in response to cytokine stimulation. Hu...

journal_title：Gut

authors： Fais S,Pallone F

更新日期：1995-12-01 00:00:00

abstract：:This is a clinical study of 81 patients (32 male and 49 female), who are not alcoholics, with jaundice of hepato-cellular type lasting longer than three months. Forty-nine of these patients were under 21 years of age. The natural history of the condition and the response to corticosteroid therapy is described; good sy...

journal_title：Gut

authors： READ AE,SHERLOCK S,HARRISON CV

更新日期：1963-12-01 00:00:00

abstract：:Thirty-two patients with diarrhoea, on average four years following truncal vagotomy and drainage, were studied. A comparison was made with 24 patients without postvagotomy diarrhoea. The incidence of bacterial colonization of the upper small intestine was no different in the two groups, though patients with a gastroe...

journal_title：Gut

authors： Browning GG,Buchan KA,Mackay C

更新日期：1974-08-01 00:00:00

abstract：BACKGROUND:Hydrogen sulphide (H(2)S) is a potent toxin normally present in the colonic lumen which may play a role in ulcerative colitis (UC). Two enzymes, thiol methyltransferase (TMT) and rhodanese (RHOD), are thought to be responsible for sulphide removal but supportive evidence is lacking. AIMS:To determine the di...

journal_title：Gut

authors： Picton R,Eggo MC,Merrill GA,Langman MJ,Singh S

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND AIMS:There are no available effective therapies for fatigue associated with chronic hepatitis C (CHC). The serotonin antagonist ondansetron has been shown to be effective in the chronic fatigue syndrome. In this randomised, placebo controlled, double blind trial, we investigated the effect of orally admi...

journal_title：Gut

authors： Piche T,Vanbiervliet G,Cherikh F,Antoun Z,Huet PM,Gelsi E,Demarquay JF,Caroli-Bosc FX,Benzaken S,Rigault MC,Renou C,Rampal P,Tran A

更新日期：2005-08-01 00:00:00