Abstract:
:The liver-derived human cell line, Hep G2, has high benzo[a]pyrene-metabolizing activity and converts benzo[a]pyrene to intermediates that are mutagenic and that bind to DNA. This cell line will be useful for studying metabolic activation of polycyclic aromatic hydrocarbons and other xenobiotics by human tissue and as an activation system in short-term screening assays for identifying compounds with carcinogenic potential for humans.
journal_name
Carcinogenesisjournal_title
Carcinogenesisauthors
Diamond L,Kruszewski F,Aden DP,Knowles BB,Baird WMdoi
10.1093/carcin/1.10.871keywords:
subject
Has Abstractpub_date
1980-01-01 00:00:00pages
871-5issue
10eissn
0143-3334issn
1460-2180journal_volume
1pub_type
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