[The value of serum tissue polypeptide specific antigen TPS concentration in therapeutic monitoring of patients with epithelial malignant ovarian neoplasms].

Abstract:

DESIGN:The aim of this study was compare the concentrations TPS and CA 125 in serum 37 patients with ovarian carcinoma in order to evaluate the usefulness of markers in monitoring therapy. MATERIAL AND METHODS:The concentrations of TPS and CA 125 were determined prior to surgery, 1 week after surgery, prior chemotherapy, after 3 and 6 course chemotherapy next every 3 months for the first year and every 6 month for the next 2 years. RESULTS:The concentration of TPS decreased above cutoff values in all patients with remission after 3 course chemotherapy, CA 125 after 6 course chemotherapy. In patients with remission the increase of TPS preceded 3 to 12 months, of CA 125 1 to 3 month the reoccurence of the disease. In of patients with progressive disease the TPS levels decreased during therapy and next rise. CONCLUSIONS:The current observations demonstrate that serial measurements of TPS appear to be useful for the evaluation of therapy and monitoring of patients.

journal_name

Ginekol Pol

journal_title

Ginekologia polska

authors

Zakrzewska I,Borawska R

keywords:

subject

Has Abstract

pub_date

2000-12-01 00:00:00

pages

1523-31

issue

12

eissn

0017-0011

issn

2543-6767

journal_volume

71

pub_type

临床试验,杂志文章
  • [Gelatinolitic and proteolytic activity of Wharton's jelly in EPH-gestosis (preeclampsia)].

    abstract::EPH-gestosis is accompanied by an extensive remodeling of the extracellular matrix of Wharton's jelly. The gelatinolytic and proteolytic activities were measured. A decrease in gelatinolityc activity and an increase in proteolytic activity in EPH-gestosis were observed. The decrease in gelatinase activity in EPH-gesto...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Sobolewski K,Galewska Z,Wolańska M,Jaworski S

    更新日期:2002-05-01 00:00:00

  • [Influence of hormone replacement therapy (oral and transdermal) on activity of erythrocyte Zn/Cu superoxide dismutase (Zn/Cu-SOD) in postmenopausal women].

    abstract:OBJECTIVE:The aim of the study was to determine the effect of hormone replacement therapy (oral and transdermal) on the erythrocyte antioxidant enzyme activity in postmenopausal women. DESIGN:Prospective clinical study. MATERIAL AND METHODS:The erythrocyte Cu/Zn superoxide dismutase activity was measured in 14 postme...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Radowicki S,Jankowska S,Kunicki M

    更新日期:2003-04-01 00:00:00

  • [The course of pregnancy with placenta praevia diagnosed in the 2nd and 3rd trimester].

    abstract::Selected clinical features of the course of pregnancy in 118 gravidas with placenta praevia diagnosed ultrasonographically on the first breeding were compared. The clinical features significantly connected with bleeding and the prognostic features for the way of delivery were stated. The longest bleeding was observed ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Schilling J

    更新日期:1992-02-01 00:00:00

  • [Comparison of the frequency of selected gynecologic operations conducted as laparotomy and laparoscopy during 1993-1997].

    abstract:UNLABELLED:The aim of the study was to compare frequency of four gynecological operations: myomectomy, tubal surgery, cystectomy and operative management of ectopic pregnancy, performed by laparotomy or laparoscopy, by the same team of surgeons. In the years 1994-1997 in Division of Reproduction Poznań University Medic...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Jedrzejczak P,Kubiaczyk B,Pisarski T,Skrzypczak J,Szymanowski K,Wilczak M,Pawelczyk L

    更新日期:2001-04-01 00:00:00

  • Increased oxidative stress is associated with insulin resistance and infertility in polycystic ovary syndrome.

    abstract:OBJECTIVES:The present study aims to investigate the role of oxidant-antioxidant status in young women with polycystic ovary syndrome (PCOS). MATERIAL AND METHODS:Seventy-one women with PCOS and 53 healthy controls are compared in aspect of demographic characteristics, biochemical data, hormones, and oxidant-antioxida...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.2016.0079

    authors: Özer A,Bakacak M,Kıran H,Ercan Ö,Köstü B,Kanat-Pektaş M,Kılınç M,Aslan F

    更新日期:2016-01-01 00:00:00

  • Smoking reduces ovarian stromal blood flow in polycystic ovary syndrome patients.

    abstract:OBJECTIVES:The objective of the current research is to compare hormonal, metabolic and ovarian stromal blood flow outcomes in smoking versus non-smoking polycystic ovary syndrome (PCOS) patients. MATERIAL AND METHODS:79 PCOS women (Group 1) and 79 healthy subjects (Group 2) were recruited. Both groups were subdivided ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.2020.0041

    authors: Emekçi Özay Ö,Özay AC

    更新日期:2020-01-01 00:00:00

  • The effectiveness of a pre-pubic four-arm NAZCA-TC mesh in treating cystocele and stress urinary incontinence simultaneously - results controlled with a pelvic floor ultrasound. A preliminary study.

    abstract:OBJECTIVES:It is controversial whether pelvic organ prolapse and stress urinary incontinence (SUI) should be treated simultaneously with a single surgery or separately with two procedures. The pre-pubic four-arm NAZCA-TC® mesh was invented to treat cystocele and SUI with a single procedure. The objective of this study ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.a2017.0105

    authors: Wlaźlak E,Kluz T,Wróbel A,Krzycka M,Surkont G

    更新日期:2017-01-01 00:00:00

  • Prospective clinical study of the association between plasma level of free IGF-1 and myometrial invasion min patients with endometrial adenocarcinoma.

    abstract:INTRODUCTION:Endometrial carcinoma is a common malignancy of the female genital tract. There is a strong correlation between myometrial invasion and clinical prognosis. Increasing myometrial penetration is associated with an increasing risk of pelvic and para-aortic lymph node metastasis, adnexal metastasis, positive p...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Baloglu A,Bezircioglu I,Cetinkaya B,Hicyilmaz L

    更新日期:2010-07-01 00:00:00

  • [A comparative analysis of selected parameters of vascular angiogenesis in placentas from dizygotic twin pregnancies].

    abstract:INTRODUCTION:Most of preIntroduction: Most pregnancies after assisted reproduction techniques are dizygotic twin gestations. There is a close relationship between the development and functioning of the placenta and the growth of both fetuses in dizygotic twin pregnancies. Angiogenesis is the process of creating new cap...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.17772/gp/1663

    authors: Orłowska K,Kowalska-Koprek U,Karowicz-Bilińska A

    更新日期:2013-11-01 00:00:00

  • [Screening for ovarian cancer in BRCA1/BRCA2 mutations carriers].

    abstract::Worldwide screening for early detection of ovarian cancer in both, the general population and the group of women at high risk for ovarian cancer including BRCA genes mutations carriers, has proven to be ineffective. The recommended screening methods, including a pelvic examination, transvaginal ultrasound, and CA125 p...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:10.17772/gp/1735

    authors: Synowiec A,Wcisło G,Bodnar L,Gasowska-Bodnar A,Szczylik C

    更新日期:2014-05-01 00:00:00

  • [Activity of endogenous anticoagulants (antithrombin III, protein C and protein S) in women after menopause treated with hormone replacement therapy (transdermal 17 beta-OH estradiol and oral medroxyprogesterone acetate)].

    abstract::The influence of hormone replacement therapy (HRT) on coagulation system has not been completely explained yet. We measured plasma activities of antithrombin III, protein C and protein S before and after 6 and 12 months of HRT in 48 postmenopausal women. HRT consisted of transdermal estradiol and orally medroxyprogest...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Ciepłuch R,Czestochowska E

    更新日期:1996-08-01 00:00:00

  • Regenerative medicine- techniques and methods of administering autologous derived stem cells in urinary incontinence.

    abstract::The aim of the work is to present regenerative medicine achievement as an alternative SUI treatment and the variety of injected cells type as well as injection techniques itself with the analysis of their quality and possible the mechanism in which they reduce urinary incontinence symptoms. For over a decade numerous ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:10.17772/gp/60973

    authors: Stangel-Wojcikiewicz K,Petko M,Kobus K,Majka M,Gołąbek T,Chłosta P,Basta A

    更新日期:2016-01-01 00:00:00

  • The risk of hyperbilirubinemia in term neonates after placental transfusion - a randomized-blinded controlled trial.

    abstract:OBJECTIVE:We aimed to demonstrate non-inferiority of delayed cord clamping (DCC) and cord milking (CM) in comparison to early cord clamping (ECC) in the incidence of hyperbilirubinemia requiring phototherapy. MATERIAL AND METHODS:467 of maternal-foetal dyads were screened for eligibility. 389 term infants, of breastfe...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.a2020.0096

    authors: Seliga-Siwecka JP,Puskarz-Gasowska J,Tolloczko J

    更新日期:2020-01-01 00:00:00

  • [Human papilloma virus infection in pregnant women with normal pap-smears, HPV oncogenity and risk factors].

    abstract:UNLABELLED:The process of carcinogenesis in both types of cervical carcinoma is dependent on the infection of oncogenic types of HPV. HPV infection could be diagnosed on the basis of whether or not the DNA virus in present. In pregnant women the latent-persistent infection easily changes into its active form. This proc...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Nowak Z,Karowicz-Bilińska A

    更新日期:2007-09-01 00:00:00

  • [Fertility after adnexal surgery].

    abstract::Among 64 women undergoing tubal-ovarian surgery 40.6% became pregnant spontaneously. Because of 47% of the remainder patients demonstrated anovulation the induction of ovulation was performed except the cases with hypergonadotrophic hypogonadism (9.4%). After treatment the total population with ovulatory cycles increa...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Jakowicki J,Putowski L,Tomaszewski J

    更新日期:1993-12-01 00:00:00

  • [Fibronectin gene expression in preneoplastic states and female genital neoplasms].

    abstract::In this paper the fibronectin gene expression level (Northern blotting) in 33 endometrial samples (residua post abortum, endometrium proliferativum, secretivum and involutivum, hyperplasia glandularis endometrii, adenocarcinoma endometrii) was measured and compared. Higher level of fibronectin gene expression level in...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Wójcicka-Bartłomiejczyk B,Sikorski R,Wojcierowski J

    更新日期:1995-08-01 00:00:00

  • [The clinical value of laboratory tests for detection of HPV infection in prevention and treatment of cervical cancer].

    abstract::The retrospective and prospective epidemiological studies were conducted in centres all over the world and showed that the main etiological factor in cervical cancer is human papillomavirus infection. The problem of detection of HPV infection is being currently under discussion. The selection of method of HPV detectio...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Łukaszuk K,Liss J

    更新日期:2002-08-01 00:00:00

  • [Prognostic value of ultrasonography of the yolk sac in singleton pregnancy].

    abstract:OBJECTIVES:The aim of the research was evaluation of the clinical usefulness of chosen ultrasonographic morphological parameters of the yolk sac in the first trimester of unifetal pregnancies. MATERIAL AND METHOD:Analysis has been done on 391 cases of unifetal pregnancies in the first trimester. Parameters of ultrason...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Roman G,Malinowski W

    更新日期:2004-08-01 00:00:00

  • Survivin--prognostic tumor biomarker in human neoplasms--review.

    abstract::Accurate diagnosis and proper monitoring of cancer patients remain important obstacles for successful cancer treatment. The search for cancer biomarkers is carried out in order to quickly identify tumor cells and predict treatment response, ultimately leading to a favorable therapeutic outcome. One such prognostic mar...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Waligórska-Stachura J,Jankowska A,Waśko R,Liebert W,Biczysko M,Czarnywojtek A,Baszko-Błaszyk D,Shimek V,Ruchała M

    更新日期:2012-07-01 00:00:00

  • [Cryopreservation of embryos--used for treatment of infertility by means of assisted reproductive techniques (ART)].

    abstract::Freezing of the human embryos has been routinely used in the world for over 10 years in the treatment of infertility by the ART. Excessive fertilized oocytes and embryos can be frozen and preserved in the temperature of liquid nitrogen. The risk of multiple pregnancies is reduced and enhancement of pregnancy rates can...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Wołczyński S

    更新日期:1996-05-01 00:00:00

  • [Insulin resistance in the pathogenesis of polycystic ovarian disease (PCOD)].

    abstract::In polycystic ovarian disease there is a strong association between hyperinsulinemia and hyperandrogenism but not with obesity alone. The magnitude of peripheral insulin resistance is similar to that seen in non-insulin-dependent diabetes mellitus. Mild hyperinsulinemia in PCOD patients is not impair the carbohydrate ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Jakowicki J

    更新日期:1994-10-01 00:00:00

  • [Acute complete uterine inversion--care report].

    abstract:OBJECTIVES:Acute puerperal uterine inversion is a rare but very feared obstetrical complication. It determines an almost immediate shock and serious metrorrhagia. It is a introflexion of parietes uteri which takes place during the third stage of labor or during the first hours of puerperium. It can be distinguished in ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Studziński Z,Branicka D

    更新日期:2001-11-01 00:00:00

  • [The role of gonadotropins, cyclic AMP, 22-R-OH-cholesterol and cofactors in regulating endocrine functions of the Leydig cells in rats. III. Mechanisms responsible for "desensitization" of the Leydig cells of rats caused by high doses of hCG].

    abstract::Two groups of rats (a control group and the group examined) were administered intraperitoneally supraphysiological doses of hCG in order to induce a "down regulation" effect on the level of receptors LH and to achieve the desensibilization of Leydig cells. The authors tried to find out at which stage of sequence of ch...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Grochowski D,Szamatowicz M

    更新日期:1989-05-01 00:00:00

  • [Treatment outcome in women suffering from recurrent miscarriages and antiphospholipid syndrome].

    abstract:OBJECTIVE:To evaluate the outcomes of treatment in patients suffering from recurrent spontaneous abortion and antiphospholipid syndrome. MATERIALS AND METHODS:148 observed women suffering from recurrent abortion with presence of lupus anticoagulant antibodies (LA) and/or high moderate concentration of anticardiolipin ...

    journal_title:Ginekologia polska

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Malinowski A,Dyński MA,Maciołek-Blewniewska G,Głowacka E,Pawłowski T,Babula G

    更新日期:2003-10-01 00:00:00

  • [Effect of immunotherapy on the level of immunoglobulin in serum of women with pruritus of the vulva].

    abstract::This study was performed in 52 women in their early postmenopausal period, divided into two equal groups. The control group included women with menopausal symptoms only, women in the study group demonstrated also pruritus. All women were on estrogen replacement therapy, additionally a bacterial auto-vaccine was admini...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Stanosz S,Sycz G,Borowiak M

    更新日期:1992-01-01 00:00:00

  • [Value of chorionic gonadotropin detection in urine samples in the diagnosis of hydatid mole (serologic technic)].

    abstract::32 patients with hydatid mole were subjected to serological tests to determine the concentration of chorionic gonadotropin (HCG) in the urine. The patients were divided into 2 groups, depending on the duration of the amenorrhea. Group 1 (20 cases) showed a uterus size not exceeding the volume of the 12th week of ges...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Wawryk J

    更新日期:1976-09-01 00:00:00

  • [An attempt to apply Spielberg's self-assessment questionnaire in cases of premenstrual syndrome in girls].

    abstract::The premenstrual syndrome occurs in the second phase of period and strain, sensitivity, nervousness, anxiety, sleeplessness, headaches, sickness, swollen breasts are the typical symptoms of the syndrome. 143 high school girls have been subjected to the anonymous questionnaire. They were divided into two groups: A--tho...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Ciszek V,Watorska H

    更新日期:1993-08-01 00:00:00

  • [The relationship between the levels of proinflammatory cytokines, and AFI value in pregnancies complicated by premature rupture of membranes].

    abstract:OBJECTIVE:The aim of the study was to test the relationship between maternal serum proinflammatory cytokines level and AFI (amniotic fluid index) in pregnancies complicated by premature rupture of membranes (PROM). MATERIALS AND METHODS:The maternal serum levels of IL-6, IL-1 beta and TNF-alfa were assessed in patient...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Poniedziałek-Czajkowska E,Leszczyńska-Gorzelak B,Oleszczuk J

    更新日期:2001-12-01 00:00:00

  • [Microvessel density index as a prognostic factor in a low histological differentiation stage of endometrial carcinoma].

    abstract:OBJECTIVE:Angiogenesis in malignant tumors is a prognostic factor associated with tumor growth and metastasis. Studies of angiogenesis in breast, prostate and lung cancer showed that neovascularisation correlates with likelihood of metastasis and recurrence. Our study was to evaluate microvessel density as a prognostic...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Szymański W,Fórmaniak J,Szymański M,Grabiec M

    更新日期:2002-11-01 00:00:00

  • [Emergency and elective cesarean section and selected elements of immunological system of full-term neonates].

    abstract:AIM OF STUDY:To define a relationship between emergency and elective indications for cesarean section and quantitative changes of percentage and quantity of T and B lymphocytes and their subpopulations in healthy full-term neonates. MATERIAL AND METHODS:The study included 43 healthy neonates born in the years 1998 - 2...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Echolc B,Mazur B,Królak-Olejnik B,Kwiecińska M,Karpe J,Grzonka D

    更新日期:2009-10-01 00:00:00