[Insulin resistance in the pathogenesis of polycystic ovarian disease (PCOD)].

Abstract:

:In polycystic ovarian disease there is a strong association between hyperinsulinemia and hyperandrogenism but not with obesity alone. The magnitude of peripheral insulin resistance is similar to that seen in non-insulin-dependent diabetes mellitus. Mild hyperinsulinemia in PCOD patients is not impair the carbohydrate metabolism. The elimination of the cause of hyperandrogenism by bilateral oophorectomy, long-acting Gn-RH agonist or antiandrogen cyproterone acetate did not improve the associated insulin resistance. In opposition to insulin resistance in the tissues responsible for metabolism of carbohydrate, the ovary remains sensitive to the effects of pancreatic hormone. Presumably this mechanism involved the interaction with IGF-I receptors to stimulate thecal and stromal androgen production. Insulin may sensitize the stroma to the stimulatory effect of LH. In the mechanism of follicular arrest take part increased level of binding proteins for IGF-I, mainly IGFBP 2, -4 and 5 inhibit FSH and IGF-I action.

journal_name

Ginekol Pol

journal_title

Ginekologia polska

authors

Jakowicki J

subject

Has Abstract

pub_date

1994-10-01 00:00:00

pages

582-6

issue

10

eissn

0017-0011

issn

2543-6767

journal_volume

65

pub_type

杂志文章,评审
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    authors: Czubalski A,Barwijuk A,Dziag R

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    authors: Szamatowicz J,Tomaszewska I,Szamatowicz M

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    abstract::Preterm labor remains to be one of the most important challenges of contemporary perinatology and constitutes the main reason of perinatal mortality and prematurity of neonates. Studies on preterm labor have confirmed the mutual interactions of several different hormonal systems while the activation of hypothalamic- p...

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    doi:

    authors: Krzyzanowski A,Karwasik-Kajszczarek K,Dymanowska-Dyjak I,Kondracka A,Kwaśniewska A

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  • [Activin A as a possible marker for hypoxia and intraventricular haemorrhage in newborns].

    abstract::The article presents general information about activin A, a glycoprotein that belongs to the transforming growth factor beta superfamily. Structure, mechanism and role of activin as a possible marker of hypoxia and intraventricular haemorrhage were described. ...

    journal_title:Ginekologia polska

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    doi:

    authors: Fiala M,Baumert M,Walencka Z

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  • Comparison of the effectiveness of cytodiagnostics, molecular identification of HPV HR and CINtecPLUS test to identify LG SIL and HG SIL.

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    authors: Rokita W,Kedzia W,Pruski D,Friebe Z,Nowak-Markwitz E,Spaczyński R,Karowicz-Bilińska A,Spaczyński M

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  • [Bilateral adnexal masses in a pregnant woman--laparoscopic management].

    abstract::A case of a 30 years old pregnant woman suffering from bilateral ovary tumour was presented. When she was sixteen weeks pregnant she had both tumours enucleated using the method of laparoscopy. Diagnostic and therapeutic process have been described. Authors are convinced that laparoscopy as a method of treatment can b...

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    doi:

    authors: Maciołek-Blewniewska G,Malinowski A,Cieślak J,Pawłowski T,Woźniak P

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  • [Tissue reaction to polypropylene mono-or multi-filament tapes used in surgical techniques of stress urinary incontinence treatment].

    abstract:OBJECTIVES:The "gold standard" in surgical treatment of stress urinary incontinence (SUI) is sling operation with polypropylene tape appliance under the mid urethra. There are two types of polypropylene tape which are the most popular nowadays. These two tapes are differently knitted so they have different biomechanica...

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    pub_type: 杂志文章

    doi:

    authors: Rechberger T,Wróbel A,Adamiak A,Skomra D,Korobowicz E,Tomaszewski J,Czuczwar M,Skorupski P

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    abstract::The prevalence of asthma has been rising in recent decades. It is the most common disease among pregnant women andaffects ca. 12% of this population. The course of asthma in pregnancy may change. In 1/3 of patients, it worsens; in 1/3 ofpatients, the symptoms are milder; in 1/3 of patients, it remains unchanged. Well-...

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    doi:10.5603/GP.2019.0080

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    更新日期:2019-01-01 00:00:00

  • [Transvaginal ultrasonography and diagnostic hysteroscopy in infertile women].

    abstract::Sensibility and specificity of transvaginal ultrasonography and diagnostic hysteroscopy were compared in 211 infertile women. Examinations were performed between 1996-2000 in I-st Department of Obstetrics and Gynecology Warsaw Medical University--Poland. Comparing results we concluded high compatibility of transvagina...

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    doi:

    authors: Bartkowiak R,Kamiński P,Marianowski L

    更新日期:2001-12-01 00:00:00

  • Iatrogenic and spontaneous late preterm twins--which are at higher risk of neonatal complications?

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  • [Chlamydia trachomatis infection and bacterial analysis in pregnant women in II and III trimester of pregnancy].

    abstract:UNLABELLED:Chlamydia trachomatis (CT) infection during pregnancy might be the reason of an increased risk of preterm delivery and premature rupture of membranes. CT could also be responsible for the presence of intrauterine growth restriction, chorionamnionitis and post partum endometritis. It is the most common sexual...

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    pub_type: 杂志文章

    doi:

    authors: Karowicz-Bilińiska A,Kuś E,Kazimiera W,Maścidło A,Brzozowski M,Niedźwiecka B,Kowalska-Koprek U

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  • [The premenstrual syndrome frequency and the intensity of its symptoms in young women and teenagers living in the Upper Silesian Industrial region].

    abstract::Contemporary home and world medical literatures deal at length with somatic and psychopathologic symptoms connected with changes taking place during the menstrual cycle. The symptoms bring about changes in women's behaviour, life activities and interpersonal relations. The majority of women suffer during the premenstr...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Ciszek-Doniec V,Poreba R,Zogała K,Olszówka P

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  • The higher risk for sperm DNA damage in infertile men.

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    authors: Gill K,Rosiak-Gill A,Jakubik J,Patorski L,Lukaszuk M,Piasecka M

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  • [Usefulness of fetal echocardiography in the prenatal diagnosis of Down syndrome based on material from the Department for Diagnosis of Congenital Malformation's of the Institute "Polish Mother's Memorial Hospital' in Lodz between 1994-1999. Part I].

    abstract::Between 1994-1999 at the Department for Diagnosis of Congenital Malformations at the PPMH Institute there were ultrasound and echocardiography examinations performed in 40 fetuses with Down Syndrome. In our study most of the cases come from low risk groups of pregnant women. Congenital heart defects (AV-canal in 13/18...

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    authors: Krasoń A,Kaczmarek P,Janiak K,Piotrowicz M,Nowicki G,Respondek-Liberska M

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  • SDF-1alpha/CXCL12 and dendritic cells in ovarian cancer microenvironment.

    abstract:AIM:To evaluate the a-chemokine stromal cell-derived factor-1 (SDF-1)/CXCL12 levels in the peritoneal fluid (PF) and plasma of patients with epithelial ovarian cancer (EOC, n=101), serous cyst (n=34) or normal controls (n=20). SDF-1alpha concentrations were correlated to myeloid (M) and lymphoid (L) dendritic cells (DC...

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    doi:

    authors: Wertel I,Polak G,Tarkowski R,Kotarska M

    更新日期:2011-06-01 00:00:00

  • [Cord blood insulin and erythropoietin levels in relation to the mode of delivery].

    abstract:UNLABELLED:The aim of the study was evaluation, whether cord blood insulin (Ic) and erythropoietin (EPO) levels differ in accordance with mode of delivery: cesarean section (CS) or vaginal delivery (VD). MATERIAL AND METHODS:The study was performed in the diabetic group consisted of 148 newborns of diabetic mothers (N...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Czeszyńska MB,Ronin-Walknowska E

    更新日期:1999-10-01 00:00:00

  • [Estimated results of prophylactic physical examinations detecting cervical cancer in Center of Oncology in Bydgoszcz in years 2001-2003].

    abstract:OBJECTIVES:Kujawsko-pomorskie province is a region with high morbidity and death-rate from uterine cervix cancer. One of the methods of improve this situation is to perform prophylactic physical examinations to find the least advanced stages as possible. DESIGN:The aim of the study was to estimate the results of proph...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Mierzwa T,Grabiec M,Walentowicz M

    更新日期:2005-09-01 00:00:00

  • [Curettage immediately after delivery].

    abstract::The purpose of the study was to compare indications for curettage directly after delivery with histologic findings. Only in 51% there was a histologic confirmation of placental or membrane tissue. Residences indications of the suspected retained placenta were wrong in 70% cases. The curetting of 75% of the patients ex...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Marcyniak M,Czajkowski K,Deregowski K,Hamela-Olkowska A,Jalinik K

    更新日期:2002-12-01 00:00:00

  • [Surgical treatment of uterine myoma: need for surgery and long-term results].

    abstract::We analysed the indications to myomectomy in females in reproductive age and estimated efficasy of this treatment. 112 patients aged 23-45 were analysed. Most common indication to this procedure were: menorrhagia--45.54%, myoma found at gynecological examination--21.43%, adnexal mass--20.54% and pelvic pain--15.18%. 5...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Płoszyński A,Gniadek R,Adamcio-Deptulska M,Mielnik J

    更新日期:1997-09-01 00:00:00

  • [Assessment of three-level selective perinatal care based on the analysis of early perinatal death rates and cesarean sections in Poland in 2008].

    abstract:AIM:The aim of the following work was to assess three-level selective perinatal care in Polish voivodeships in 2008 on the basis of the following parameters: birth rates as well as perinatal death rates, divided into three classes of neonatal weights, in hospitals on each of the three levels. The goal of selective peri...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Troszyński M,Niemiec T,Wilczyńska A

    更新日期:2009-09-01 00:00:00

  • [Agenesis of the ductus venosus--an irrelevant anomaly or a severe clinical problem?].

    abstract:BACKGROUND:Ductus venosus is the fetal blood vessel connecting the abdominal portion of the umbilical vein with the inferior vena cava. Numerous studies have confirmed the important role of this vessel in fetal circulation. There are, however cases when finding the ductus venosus during an ultrasound examination is imp...

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    pub_type: 杂志文章

    doi:10.17772/gp/1623

    authors: Cnota W,Włoch A,Czuba B,Wójtowicz D,Sodowski K

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  • [SARS-CoV infection and pregnancy].

    abstract::SARS is a highly contagious infection, caused by new coronavirus SARS-CoV. Immunopathological mechanisms responsible for the reaction to SARS-CoV infection have not yet been fully elucidated. Cytokine profile of SARS patients showed marked elevation of Th1 cytokine, interferon gamma, inflammatory cytokines for at leas...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Ksiezakowska K,Laszczyk M,Wilczyński J,Nowakowska D

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  • [Hormone replacement therapy and cardio-vascular disease].

    abstract::The results of large randomized trials such as the Women's Health Initiative (WHI), Heart and Estrogen / Progestin Replacement Study (HERS) or Estrogen Replacement and Atherosclerosis Study (ERAS) as well as the Million Women Study (MWS) which does not meet criteria RCT, concerning, among others the impact of HRT on b...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:10.17772/gp/61022

    authors: Lesiak M,Mariola RL,Podkowa N

    更新日期:2016-01-01 00:00:00

  • [Hysterectomy after caesarean section].

    abstract:OBJECTIVES:The indications for hysterectomy after caesarean section, postoperative period, and pathological examination of women. In whom hysterectomy hampered operated delivery, are being hereby analysed. MATERIALS AND METHODS:The study group consisted of 15 patients who gave birth in I Clinic Medical Academy in Wars...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Gajewska M,Marianowski L,Szymańska K

    更新日期:2003-06-01 00:00:00

  • [Nasal bone (NB) length measurement in the first trimester of pregnancy in Polish population and its validity as fetal aneuploidy indicator].

    abstract:OBJECTIVES:Dynamic development of prenatal diagnostics is mostly directed towards search for non-invasive screening. The main role of the screening methods is to select high-risk fetal aneuploidy group of pregnant women. The base for the prenatal screening in modern obstetrics is ultrasound scanning. DESIGN:The aim of...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Sieroszewski P,Baś-Budecka E,Perenc M

    更新日期:2007-08-01 00:00:00

  • [Emergency cerclage with concomitant amniocentesis as a method of treatment of membranes prolapse--case report].

    abstract::Emergency cerclage was performed on 27 years old patient with membrane prolapse in 21 weeks' gestation. Ultrasonographically guided amniocentesis was performed intraoperatively in order to decrease intraamniotic pressure. Aggressive prophylactic management (wide spectrum antibiotics and tocolysis-nifedipine) resulted ...

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    pub_type: 杂志文章

    doi:

    authors: Rechberger T,Pietras G,Adamiak A

    更新日期:2001-12-01 00:00:00

  • [Peculiarities of multiple pregnancy: complications].

    abstract::Multiple pregnancies are considered high risk. This qualification is associated with the multitude of conditions which are known to complicated these pregnancies. Early diagnosis of these complications is the fundamental element of clinical managements. In numerous cases therapeutic protocols are widely known and in m...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Leszczyńska-Gorzelak B,Oleszczuk JJ,Machin GA,Sawulicka-Oleszczuk H,Kiczyńska A,Keith LG

    更新日期:2000-11-01 00:00:00

  • [Influence of betamethasone on glucose consumption in the human placenta perfused in vitro].

    abstract::The study was carried out on 48 human placentas perfused in vitro. Betamethasone was administered into the arterial systems in the following single doses: 0.4 mg, 2 mg and 10 mg. The authors found a highly significant or statistically insignificant decreased glucose consumption after administering each dose of betamet...

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    pub_type: 杂志文章

    doi:

    authors: Kraczkowski J,Grudzień M,Zrubek H,Oleszczuk J,Billewicz-Kraczkowska A,Szuba M

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  • [Laparoscopy in clinical practice. II. Usefulness in diagnosis of sterility].

    abstract::The paper presents results of 1099 laparoscopies performed in sterility. Laparoscopy was made in the second phase of the menstrual cycle, 5 to 7 days after probable ovulation, as a last stage in diagnosis of sterility. Normal state of genital organs and minor pelvis was noted in 20.9% of investigated patients. In the ...

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    pub_type: 杂志文章

    doi:

    authors: Blecharz A,Rzempołuch J,Horak S,Szustak J,Wolf A,Kruk M

    更新日期:1993-04-01 00:00:00

  • [Prenatal ultrasound findings in complete trisomy 9].

    abstract::This case report describes a 40-year-old woman, primigravida. On 13,3 weeks of gestation we diagnosed an abnormal flow pattern in the umbilical artery and abnormal hyperechogenic structure in fetal abdomen. In next sonographic examination on 16 weeks of gestation we diagnosed ventriculomegaly and ahydramnion. We also ...

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    pub_type: 杂志文章

    doi:

    authors: Borowski D,Hincz P,Wyrwas D,Kunert A,Szaflik K,Ałaszewski W,Grzesiak M,Jakubowski L,Bielak A,Wilczyński J

    更新日期:2006-05-01 00:00:00