Patterns of spread in biological invasions dominated by long-distance jump dispersal: Insights from Argentine ants.

abstract：:Canonical Wnt signaling plays an important role in development and disease, regulating transcription of target genes and stabilizing many proteins phosphorylated by glycogen synthase kinase 3 (GSK3). We observed that the MiT family of transcription factors, which includes the melanoma oncogene MITF (micropthalmia-asso...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Ploper D,Taelman VF,Robert L,Perez BS,Titz B,Chen HW,Graeber TG,von Euw E,Ribas A,De Robertis EM

更新日期：2015-02-03 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV), etiologically associated with Kaposi's sarcoma, uses integrins (α3β1, αVβ3, and αVβ5) and associated signaling to enter human dermal microvascular endothelial cells (HMVEC-d), an in vivo target of infection. KSHV infection activated c-Cbl, which induced the selective tra...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Chakraborty S,Veettil MV,Bottero V,Chandran B

更新日期：2012-05-08 00:00:00

abstract：:Cellular transformation by the BCR/ABL oncogene depends on the ABL-encoded tyrosine kinase activity. To block BCR/ABL function, we created a unique tyrosine phosphatase by fusing the catalytic domain of SHP1 (SHP1c) to the ABL binding domain (ABD) of RIN1, an established binding partner and substrate for c-ABL and BCR...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Lim YM,Wong S,Lau G,Witte ON,Colicelli J

更新日期：2000-10-24 00:00:00

abstract：:Molecular mechanisms that initiate meiosis have been studied in fungi and mammals, but little is known about the mechanisms directing the meiosis transition in other organisms. To elucidate meiosis initiation in plants, we characterized and cloned the ameiotic1 (am1) gene, which affects the transition to meiosis and p...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Pawlowski WP,Wang CJ,Golubovskaya IN,Szymaniak JM,Shi L,Hamant O,Zhu T,Harper L,Sheridan WF,Cande WZ

更新日期：2009-03-03 00:00:00

abstract：:The nucleotide cyclic di-3',5'- adenosine monophosphate (c-di-AMP) was recently identified as an essential and widespread second messenger in bacterial signaling. Among c-di-AMP-producing bacteria, altered nucleotide levels result in several physiological defects and attenuated virulence. Thus, a detailed molecular un...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Huynh TN,Luo S,Pensinger D,Sauer JD,Tong L,Woodward JJ

更新日期：2015-02-17 00:00:00

abstract：:Although an inverse relationship is expected in ancient DNA samples between the number of surviving DNA fragments and their length, ancient DNA sequencing libraries are strikingly deficient in molecules shorter than 40 bp. We find that a loss of short molecules can occur during DNA extraction and present an improved s...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Dabney J,Knapp M,Glocke I,Gansauge MT,Weihmann A,Nickel B,Valdiosera C,García N,Pääbo S,Arsuaga JL,Meyer M

更新日期：2013-09-24 00:00:00

abstract：:Male white Swiss mice that had previously been made aggressive by several weeks of individual housing were allowed to fight for 5 to 10 minutes each day for 5, 10, or 14 consecutive days; fighting caused a marked enlargement of their adrenals, spleens, and hearts, and a large increase in adrenal catecholamines; brain ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Welch BL,Welch AS

更新日期：1969-09-01 00:00:00

abstract：:We image macroscopic transient pores in mechanically stretched giant vesicles. Holes open above a critical radius r(c1), grow up to a radius r(c2), and close. We interpret the upper limit r(c2) by a relaxation of the membrane tension as the holes expand. The closing of the holes is caused by a further relaxation of th...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Sandre O,Moreaux L,Brochard-Wyart F

更新日期：1999-09-14 00:00:00

abstract：:T cells react to extremely small numbers of activating agonist peptides. Spatial organization of T-cell receptors (TCR) and their peptide-major histocompatibility complex (pMHC) ligands into microclusters is correlated with T-cell activation. Here we have designed an experimental strategy that enables control over the...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Manz BN,Jackson BL,Petit RS,Dustin ML,Groves J

更新日期：2011-05-31 00:00:00

abstract：:Chromosomal RNA was isolated from several rat tissues by a new technique. It is shown by RNA-DNA hybridization that each tissue contains a distinct population of chromosomal RNA sequences. This finding is compatible with the proposal that chromosomal RNA is involved in the process of gene activation. ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Mayfield JE,Bonner J

更新日期：1971-11-01 00:00:00

abstract：:Neonates suffer high morbidity and mortality in infection, presumably because of the lack of a fully developed adaptive and innate immune system. Evidence of poor innate responses in neonates has been shown by using a model that sensitizes the host to Toll-like receptor (TLR)-mediated inflammation with d-galactosamine...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Zhao J,Kim KD,Yang X,Auh S,Fu YX,Tang H

更新日期：2008-05-27 00:00:00

abstract：:After more than two decades of study, many fundamental questions remain unanswered about the dynamics of glass-forming materials confined to thin films. Experiments and simulations indicate that free interfaces enhance dynamics over length scales larger than molecular sizes, and this effect strengthens at lower temper...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Ivancic RJS,Riggleman RA

更新日期：2020-10-13 00:00:00

abstract：:The harvest of wildlife for human consumption is valued at several billion dollars annually and provides an essential source of meat for hundreds of millions of rural people living in poverty. This harvest is also considered among the greatest threats to biodiversity throughout Africa, Asia, and Latin America. Economi...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Brashares JS,Golden CD,Weinbaum KZ,Barrett CB,Okello GV

更新日期：2011-08-23 00:00:00

abstract：:Irrigation of the dog's oxyntic glandular mucosa contained in a chronically prepared, vagally denervated, separated pouch of the dog's stomach with a solution (0.5 mg ml-1) of lyophilized venom of the hooded cobra (Naja naja) increases the permeability of the mucosa. If irrigation with venom solution is repeated at we...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Davenport HW

更新日期：1976-03-01 00:00:00

abstract：:In 1989, populations of North American gypsy moth, Lymantria dispar, in seven contiguous northeastern states were severely reduced by a fungal pathogen. Based on morphology, development, and pathology, this organism appeared to be Entomophaga maimaiga. We have now used allozyme and restriction fragment length polymorp...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hajek AE,Humber RA,Elkinton JS,May B,Walsh SR,Silver JC

更新日期：1990-09-01 00:00:00

abstract：:The G12 subfamily of heterotrimeric G proteins, comprised of the alpha-subunits Galpha12 and Galpha13, has been implicated as a signaling component in cellular processes ranging from cytoskeletal changes to cell growth and oncogenesis. In an attempt to elucidate specific roles of this subfamily in cell regulation, we ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Meigs TE,Fields TA,McKee DD,Casey PJ

更新日期：2001-01-16 00:00:00

abstract：:The formation and migration of disconnections (line defects constrained to the grain boundary [GB] plane with both dislocation and step character) control many of the kinetic and dynamical properties of GBs and the polycrystalline materials of which they are central constituents. We demonstrate that GBs undergo a fini...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Chen K,Srolovitz DJ,Han J

更新日期：2020-12-29 00:00:00

abstract：:The hypothesis that intracellular Ca2+ is an essential component of the intracellular mechanism of insulin action in the adipocyte was evaluated. Cells were loaded with the Ca2+ chelator quin-2, by preincubating them with quin-2 AM, the tetrakis(acetoxymethyl) ester of quin-2. Quin-2 loading inhibited insulin-stimulat...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Pershadsingh HA,Shade DL,Delfert DM,McDonald JM

更新日期：1987-02-01 00:00:00

abstract：:Some trypanosomatid protozoa (order Kinetoplastida) are well known to harbor bacterial endosymbionts. Their phylogenetic positions and evolutionary relationships with the hosts were deduced by comparing the rRNA gene sequences. Earlier, we observed that these symbionts from three Crithidia spp. are identical and are c...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Du Y,Maslov DA,Chang KP

更新日期：1994-08-30 00:00:00

abstract：:This report provides direct evidence that strigolactone (SL) positively regulates drought and high salinity responses in Arabidopsis. Both SL-deficient and SL-response [more axillary growth (max)] mutants exhibited hypersensitivity to drought and salt stress, which was associated with shoot- rather than root-related t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Ha CV,Leyva-González MA,Osakabe Y,Tran UT,Nishiyama R,Watanabe Y,Tanaka M,Seki M,Yamaguchi S,Dong NV,Yamaguchi-Shinozaki K,Shinozaki K,Herrera-Estrella L,Tran LS

更新日期：2014-01-14 00:00:00

abstract：:Replication of HIV-1 and N-tropic murine leukemia virus (N-MLV) is restricted in a number of different primate cells. In some cell lines, cross-saturation experiments suggest that the two viruses are interacting with the same restriction factor. Recently, Trim5alpha protein from rhesus monkey was found to restrict HIV...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yap MW,Nisole S,Lynch C,Stoye JP

更新日期：2004-07-20 00:00:00

abstract：:The present investigation studied the influence of the blastocyst's state of activity on the "window" of implantation in the receptive uterus in the mouse. The receptive state of the uterus is defined as the limited time when the uterine milieu is favorable to blastocyst acceptance and implantation. In the mouse, impl...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Paria BC,Huet-Hudson YM,Dey SK

更新日期：1993-11-01 00:00:00

abstract：:An endogenous circadian biological clock controls the temporal aspects of life in most organisms, including rhythmic control of genes involved in clock output pathways. In the fungus Neurospora crassa, one pathway known to be under control of the clock is asexual spore (conidia) development. To understand more fully t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Bell-Pedersen D,Shinohara ML,Loros JJ,Dunlap JC

更新日期：1996-11-12 00:00:00

abstract：:Granulocyte-colony stimulating factor (G-CSF) promotes mobilization of CD11b(+)Gr1(+) myeloid cells and has been implicated in resistance to anti-VEGF therapy in mouse models. High G-CSF production has been associated with a poor prognosis in cancer patients. Here we show that activation of the RAS/MEK/ERK pathway reg...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Phan VT,Wu X,Cheng JH,Sheng RX,Chung AS,Zhuang G,Tran C,Song Q,Kowanetz M,Sambrone A,Tan M,Meng YG,Jackson EL,Peale FV,Junttila MR,Ferrara N

更新日期：2013-04-09 00:00:00

abstract：:Cytochrome c maturation in Escherichia coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperone that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. In this work we addressed the functions of the ccmABCD...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Schulz H,Fabianek RA,Pellicioli EC,Hennecke H,Thöny-Meyer L

更新日期：1999-05-25 00:00:00

abstract：:Natural killer (NK) cells are key players in the innate response to viruses, including herpesviruses. In particular, the variety of viral strategies to modulate the recognition of certain herpesviruses witnesses the importance of NK cells in the control of this group of viruses. Still, NK evasion strategies have remai...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Grauwet K,Cantoni C,Parodi M,De Maria A,Devriendt B,Pende D,Moretta L,Vitale M,Favoreel HW

更新日期：2014-11-11 00:00:00

abstract：:Arguably the most foundational principle in perception research is that our experience of the world goes beyond the retinal image; we perceive the distal environment itself, not the proximal stimulation it causes. Shape may be the paradigm case of such "unconscious inference": When a coin is rotated in depth, we infer...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Morales J,Bax A,Firestone C

更新日期：2020-06-30 00:00:00

abstract：:Repeated within-day testing on a texture discrimination task leads to retinotopically specific decreases in performance. Although perceptual learning has been shown to be highly specific to the retinotopic location and characteristics of the trained stimulus, the specificity of perceptual deterioration has not been st...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Mednick SC,Arman AC,Boynton GM

更新日期：2005-03-08 00:00:00

abstract：:The minimal size of the recombination site required for efficient FLP recombinase-catalyzed recombination in vitro is no more than 28 base pairs, which includes parts of two 13-base-pair inverted repeats and all of an 8-base-pair spacer. The FLP recombinase cleaves the DNA at the boundaries of the spacer, becomes cova...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Senecoff JF,Bruckner RC,Cox MM

更新日期：1985-11-01 00:00:00

abstract：:Humans are consciously aware of some memories and can make verbal reports about these memories. Other memories cannot be brought to consciousness, even though they influence behavior. This conspicuous difference in access to memories is central in taxonomies of human memory systems but has been difficult to document i...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hampton RR

更新日期：2001-04-24 00:00:00