Abstract:
:Single-unit recordings were made from lateral hypothalamic area (LHA) neurons of infant (8 through 21 days of age) male and female albino rats. Basal (or spontaneous) firing rates of LHA neurons were recorded for 20 min from rats 8 through 21 days of age, and mean basal firing rates did not differ across ages. Basal firing rates of LHA neurons in infant rats ranged from less than 1 spike/sec up to 27 spikes/sec, with 56% of the basal rates less than 1 spike/sec. Infant rats also received hypertonic saline injections (and control injections) to determine osmosensitivity characteristics of LHA neurons. Across ages, 56%--88% of LHA neurons were osmosensitive, with the highest percentages of osmosensitive units found in rats 14--21 days of age. Infant rats showed LHA unit electrophysiological characteristics that were quite similar to those obtained from LHA neurons in adult rats with respect to basal firing rates and osmosensitivity, however, LHA neuron activity in infants was not modulated by sensory stimuli as is frequently reported for adults. The results are discussed in terms of functional development of the LHA.
journal_name
Brain Res Bulljournal_title
Brain research bulletinauthors
Almli CR,McMullen NT,Golden GTdoi
10.1016/0361-9230(76)90081-2keywords:
subject
Has Abstractpub_date
1976-11-01 00:00:00pages
543-52issue
6eissn
0361-9230issn
1873-2747pii
0361-9230(76)90081-2journal_volume
1pub_type
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journal_title:Brain research bulletin
pub_type: 杂志文章
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journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2008.02.028
更新日期:2008-07-01 00:00:00
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journal_title:Brain research bulletin
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更新日期:2016-03-01 00:00:00
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journal_title:Brain research bulletin
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更新日期:2017-09-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章,评审
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更新日期:2001-02-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
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更新日期:2010-11-20 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章,评审
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更新日期:1997-01-01 00:00:00