Abstract:
:We describe a unique case of adult T-cell leukemia/lymphoma (ATL). The patient had typical clinicohematological features as ATL, but showed a lack of antibody to human T-cell leukemia virus type-1 (HTLV-1) and was negative for HTLV-1 proviral DNA in the peripheral mononuclear cells by means of polymerase chain reaction. The phenotype of tumor cells revealed CD7+, CD5+, CD2+, CD3+, WT31-, TcR delta 1-, CD4-, CD8-, CD25-, and the karyotype showed a 5q-, t(12;18). HTLV-1 unrelated ATL is very rare, and the karyotype as in our case has not been reported previously.
journal_name
Am J Hematoljournal_title
American journal of hematologyauthors
Nakase K,Hasegawa M,Tsuji K,Ikeda T,Tamaki S,Tanigawa M,Miyanishi E,Shiku Hdoi
10.1002/(sici)1096-8652(200005)64:1<64::aid-ajh11>keywords:
subject
Has Abstractpub_date
2000-05-01 00:00:00pages
64-6issue
1eissn
0361-8609issn
1096-8652pii
10.1002/(SICI)1096-8652(200005)64:1<64::AID-AJH11>journal_volume
64pub_type
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