Teardrop-shaped red cells in autoimmune hemolytic anemia.

abstract：:We report a case of a patient who developed a fatal adult respiratory distress syndrome (ARDS) during treatment with rh granulocyte-macrophage colony stimulating factor (rhGM-CSF) (250 mcg/m2/day s.c.) and low-dose cytosine-arabinoside (Ara-C) (20 mg/m2/day s.c.). Several mechanisms which might explain the lung tissue...

journal_title：American journal of hematology

authors： Verhoef G,Boogaerts M

更新日期：1991-04-01 00:00:00

abstract：:Human theta (theta 1)-globin gene represents a member of the alpha-like globin gene family residing on chromosome 16. theta 1-Specific transcripts have been detected so far only in erythroid tissues and in erythroleukemia K562 cells. To investigate systematically its inducible expression and developmental specificity,...

journal_title：American journal of hematology

authors： Mamalaki A,Anagnou NP,Moschonas NK

更新日期：1990-12-01 00:00:00

abstract：:The soluble form of Fas (sFas) can block apoptosis induced by the Fas ligand in vitro. A recent report demonstrated that mice injected with sFas displayed autoimmune features. Therefore, an elevated serum concentration of sFas may be associated with lymphoproliferation and autoimmune diseases. We measured the serum co...

journal_title：American journal of hematology

authors： Yufu Y,Choi I,Hirase N,Tokoro A,Noguchi Y,Goto T,Uike N,Kozuru M

更新日期：1998-08-01 00:00:00

abstract：:Chronic myeloid leukemia (CML) is considered to be a pleuripotential stem cell disorder with the capacity to differentiate into myeloid, erythroid, megakaryocytic, and lymphoid cell lines. Consequently, blast crisis (BC) involving each of the above lineages has been well described. Among lymphoblastic crises, differen...

journal_title：American journal of hematology

authors： Advani SH,Malhotra H,Kadam PR,Iyer RS,Nanjangud G,Balsara B,Saikia T,Gopal R,Nair CN

更新日期：1991-02-01 00:00:00

abstract：:Cobalamin (vitamin B12) deficiency is a common cause of megaloblastic anemia in Western populations. Laboratory evaluation of megaloblastic anemia frequently includes the assessment of patient cobalamin and folate status. Current total serum cobalamin measurements are performed in the clinical laboratory with competit...

journal_title：American journal of hematology

authors： Oberley MJ,Yang DT

更新日期：2013-06-01 00:00:00

abstract：DISEASE OVERVIEW:Chronic neutrophilic leukemia (CNL) is a rare, often aggressive myeloproliferative neoplasm (MPN) defined by persistent mature neutrophilic leukocytosis, bone marrow granulocyte hyperplasia, and frequent hepatosplenomegaly. The seminal discovery of oncogenic driver mutations in colony-stimulating facto...

journal_title：American journal of hematology

authors： Szuber N,Elliott M,Tefferi A

更新日期：2020-02-01 00:00:00

abstract：:Plasma cell dyscrasias are a group of clinically and biochemically diverse disorders of unknown etiology, characterized by the disproportionate proliferation of one or more clones of B cells, and the presence of a structurally and electrophoretically homogeneous (monoclonal) immunoglobulin or polypeptide subunit in se...

journal_title：American journal of hematology

authors： Kapoor P,Singh E,Radhakrishnan P,Mehta P

更新日期：2006-12-01 00:00:00

abstract：:Selective labeling of phagocytes in human blood can be achieved by incubation of unseparated, heparinized blood with 99mTc-sulfur colloid. We have developed a method for quantitation of granulocyte chemotaxis using granulocytes labeled by this technique. The method was found to be more accurate and less tedious to per...

journal_title：American journal of hematology

authors： English D,McPherson TA

更新日期：1977-01-01 00:00:00

abstract：:A 56-year-old man was admitted to our hospital with leukocytosis, anemia, and thrombocytopenia. Acute monoblastic leukemia was diagnosed. Two subsequent courses of consolidation chemotherapy consisted of conventional doses of cytarabine and intermediate-dose cytarabine. Intermediate-dose cytarabine was infused intrave...

journal_title：American journal of hematology

authors： Saito B,Nakamaki T,Nakashima H,Usui T,Hattori N,Kawakami K,Tomoyasu S

更新日期：2007-04-01 00:00:00

abstract：:We examined inter- and intraobserver reproducibility and concordance between histological diagnosis and independently collected clinical findings in a large series of patients with the major subtypes of myeloproliferative neoplasms (MPNs) and controls. Seven hematopathologists reviewed 272 bone marrow biopsies includi...

journal_title：American journal of hematology

authors： Madelung AB,Bondo H,Stamp I,Loevgreen P,Nielsen SL,Falensteen A,Knudsen H,Ehinger M,Dahl-Sørensen R,Mortensen NB,Svendsen KD,Lange T,Ralfkiaer E,Nielsen K,Hasselbalch HC,Thiele J

更新日期：2013-12-01 00:00:00

abstract：:This study investigated the clinical characteristics and prognostic relevance of CD34 expression in 47 patients with acute promyelocytic leukemia (APL), showing t(15;17) or PML/RARalpha. Ten (21.3%) of the APL patients were CD34(+). CD34 expression was associated with hypogranular morphology (P = 0.002) and hyperleuko...

journal_title：American journal of hematology

authors： Lee JJ,Cho D,Chung IJ,Cho SH,Park KS,Park MR,Ryang DW,Kim HJ

更新日期：2003-07-01 00:00:00

abstract：:A specialized serum ferritin assay has been developed for the detection of iron deficiency in epidemiologic studies. An enzyme immunoassay (EIA) was employed to eliminate the need for radioisotopes. The problem of low sensitivity inherent with the EIA for serum ferritin was eliminated by the use of monoclonal immunolo...

journal_title：American journal of hematology

authors： Flowers CA,Kuizon M,Beard JL,Skikne BS,Covell AM,Cook JD

更新日期：1986-10-01 00:00:00

abstract：:Acute myeloid leukemia (AML) with mutated NPM1 is a newly recognized separate entity in the revised 2016 WHO classification, and is associated with a favorable prognosis. While previous studies have evaluated NPM1 in a binary fashion, we recently demonstrated a significant independent negative prognostic effect of hig...

journal_title：American journal of hematology

authors： Patel SS,Pinkus GS,Ritterhouse LL,Segal JP,Dal Cin P,Restrepo T,Harris MH,Stone RM,Hasserjian RP,Weinberg OK

更新日期：2019-08-01 00:00:00

abstract：:Extensive extralymphatic Hodgkin disease developed in a young man with common variable immunodeficiency manifested by hypogammaglobulinemia, recurrent sinopulmonary infections, and multiple autoimmune phenomena. Both humoral and cell-mediated immune dysfunction were present prior to treatment. After two cycles of chem...

journal_title：American journal of hematology

authors： Fesus SM,Hagemeister FB,Manning J

更新日期：1989-10-01 00:00:00

abstract：:Fifteen recently diagnosed patients with acute leukemias admitted for induction chemotherapy were selected for study. When thrombocytopenic (venous platelet count less than 20 X 10(9)/l) these patients received prophylactic platelet transfusions. A total of 67 platelet transfusion therapies were administered and evalu...

journal_title：American journal of hematology

authors： Kutti J,Zaroulis CG,Safai-Kutti S,Dinsmore RE,Day NK,Good RA

更新日期：1981-11-01 00:00:00

abstract：:Withdrawal: Primary prevention of sickle cell disease using preimplantation genetic testing and in vitro fertilization is cost-effective. The above article, published online on 20 August 2020 in Wiley Online Library (wileyonlinelibrary.com) as an Accepted Article, has been withdrawn by agreement between the authors, t...

journal_title：American journal of hematology

authors： Cordeiro Mitchell CN,Pradhan A,Singh B,Naik RP,Baker VL,Lanzkron SM,Christianson MS,Pecker LH

更新日期：2020-08-20 00:00:00

abstract：:The arachidonic acid metabolites produced by human peripheral blood monocytes were studied to determine which metabolites could have a role in thrombogenesis. Monocytes were found to be free of platelets by scanning electron microscopy and by measurement of 12-HETE. Human peripheral blood monocytes produce thromboxane...

journal_title：American journal of hematology

authors： Jones CM,Hall ER,Hester JP,Wu KK

更新日期：1989-07-01 00:00:00

abstract：:"Autonomous" development of erythroid colonies in erythropoietin (EPO)-free semi-solid culture has been used as an in vitro assay for diagnosis of polycythemia vera (PV). These colonies, however, are small and poorly hemoglobinized, rendering the assay in many cases unreliable. We report here on the use of a novel ass...

journal_title：American journal of hematology

authors： Manor D,Rachmilewitz EA,Fibach E

更新日期：1997-01-01 00:00:00

abstract：:Mantle cell lymphoma (MCL) is a unique type of lymphoma with a prognosis intermediate between indolent and aggressive types. The purpose of this study was to study blood cytokine levels in newly diagnosed and relapsed MCL patients with respect to patterns of abnormalities and relationship to the MCL International Prog...

journal_title：American journal of hematology

authors： Sonbol MB,Maurer MJ,Stenson MJ,Allmer C,LaPlant BR,Weiner GJ,Macon WR,Cerhan JR,Witzig TE,Gupta M

更新日期：2014-12-01 00:00:00

abstract：:Although infectious complications represent a relevant cause of morbidity and mortality in patients with myelofibrosis (MF), little is known about their incidence, outcome and risk factors. We retrospectively evaluated a cohort of 507 MF patients, diagnosed between 1980 and 2014 in five Italian hematology centers, to ...

journal_title：American journal of hematology

authors： Polverelli N,Breccia M,Benevolo G,Martino B,Tieghi A,Latagliata R,Sabattini E,Riminucci M,Godio L,Catani L,Nicolosi M,Perricone M,Sollazzo D,Colafigli G,Campana A,Merli F,Vitolo U,Alimena G,Martinelli G,Lewis RE,V

更新日期：2017-01-01 00:00:00

abstract：:Since platelets express both platelet-specific and class I HLA antigens, serum antiplatelet reactivity assessed by most platelet antibody techniques could be due to antibodies with either or both specificities. Flow cytometric analysis of sera for detection of antiplatelet antibody commonly employs a purified platelet...

journal_title：American journal of hematology

authors： Freedman J,Hornstein A

更新日期：1991-12-01 00:00:00

abstract：:Cephalosporins are commonly used drugs that interact with red blood cell membranes. They frequently cause a positive direct antiglobulin test but rarely cause hemolysis. A case of cefotetan-induced hemolytic anemia is described in which two types of antibodies were detected. One reacted with red blood cells by a hapte...

journal_title：American journal of hematology

authors： Ehmann WC

更新日期：1992-06-01 00:00:00

abstract：:The purpose of this study was to determine if therapeutic levels of Rituximab could be achieved in a patient with renal failure being dialyzed and if Rituximab is removed by hemodialysis. A 54-year-old man with low-grade lymphoma and renal failure on hemodialysis received 8 weekly treatments of Rituximab at 375 mg/M(2...

journal_title：American journal of hematology

authors： Jillella AP,Dainer PM,Kallab AM,Ustun C

更新日期：2002-11-01 00:00:00

abstract：:Recent observations that the sickle RBC are excessively susceptible to phagocytosis by macrophages in vitro prompted me to look for evidence of in vivo erythrophagocytosis (Ep) in patients with sickle cell anemia (SS). Freshly prepared smears of unmanipulated blood of 27 patients with SS in steady state were examined ...

journal_title：American journal of hematology

authors： Solanki DL

更新日期：1985-12-01 00:00:00

abstract：:Familial and metachronous aggregations of malignant lymphoma are well-documented, but the molecular basis of a predisposition for development of lymphoma is as yet unclear. Malignant lymphomas have been described as part of the spectrum of neoplasias in Li-Fraumeni syndrome (LFS), which is associated with constitution...

journal_title：American journal of hematology

authors： Pötzsch C,Schaefer HE,Lübbert M

更新日期：1999-11-01 00:00:00

abstract：:Eight patients with severe chronic autoimmune thrombocytopenic purpura (AITP) refractory to high-dose intravenous immunoglobulin (IVIgG) and/or oral prednisone were treated with one to three infusions of high-dose methylprednisolone (HDMP) (15 mg/kg/day). The mean platelet count before treatment was 12 +/- 10 x 10(9)/...

journal_title：American journal of hematology

authors： Godeau B,Zini JM,Schaeffer A,Bierling P

更新日期：1995-04-01 00:00:00

abstract：:The Muir-Torre syndrome (MTS) is defined as the concurrent or sequential discovery of at least one sebaceous gland tumor and a minimum of one internal malignancy. A man with Hodgkin's lymphoma who subsequently developed an ocular sebaceous carcinoma in situ is described and the world literature of patients with the MT...

journal_title：American journal of hematology

authors： Cohen PR

更新日期：1992-05-01 00:00:00

abstract：:A 74-year old woman with Ph1-negative chronic myelogenous leukemia (CML) and heterozygous for glucose-6-phosphate dehydrogenase (G6PD) was studied. Both A and B types of G6PD were found in skin. In contrast, white blood cells and platelets showed only a single G6PD type A. These results provide further evidence that P...

journal_title：American journal of hematology

authors： Kaye FJ,Najfeld V,Singer J,Cuttner J,Fialkow PJ

更新日期：1984-07-01 00:00:00

abstract：:Micro-transplantation (MST) by chemotherapy, combined with granulocyte colony-stimulating factor-mobilized peripheral blood stem cell (GPBSC) infusion, from an HLA partial matched related donor has shown some encouraging effective therapy for acute myeloid leukemia (AML). However, the outcome of human leukocyte antige...

journal_title：American journal of hematology

authors： Hu KX,Du X,Guo M,Yu CL,Qiao JH,Sun QY,Zuo HL,Cai B,Huang YJ,Ai HS,Dong Z,Wang Y

更新日期：2020-06-01 00:00:00

abstract：:Twenty-eight patients undergoing cardiac surgery were prospectively studied and were assigned to two groups. The patients received 0.8- (Group L) or 2.0-fold (Group H) dose of protamine for the neutralization after cardiopulmonary bypass (CPB) which was determined by Hepcon HMS(R) assay system in which the reagent cha...

journal_title：American journal of hematology

authors： Miyashita T,Nakajima T,Hayashi Y,Kuro M

更新日期：2000-06-01 00:00:00