Abstract:
:It is a common clinical practice to estimate FSH, LH and testosterone levels in patients with unilateral undescended testis (U/L UDT) as a prognostic pointer to fertility potential. Is this practice correct? To ascertain this aspect, new born rats were operated to create experimental U/L UDT by gubernaculectomy and anchoring the gubernaculum to anterior abdominal wall. Fertility and hormone levels were evaluated later in adult life. Though fertility of rats with U/L UDT was significantly less (p < 0.01) than the controls, no significant alterations were found in the levels of serum testosterone, FSH and LH. Even though variations in the hormone levels may be responsible, to a certain extent, for the decrease in fertility potential in U/L UDT, estimation of sex hormone levels in U/L UDT is not a sensitive indicator of fertility potential. U/L UDT may additionally be affecting fertility through non-endocrinological mechanisms.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Srinivas M,Agarwala S,Jha P,Misro MM,Mitra DKdoi
10.1007/BF02761205keywords:
subject
Has Abstractpub_date
1999-03-01 00:00:00pages
193-6issue
2eissn
0019-5456issn
0973-7693journal_volume
66pub_type
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