Abstract：
OBJECTIVES:To study whether orogastric tube (OGT) insertion elicits a painful response in preterm neonates, and the role of oral sucrose in reducing this pain. METHODS:This double blinded, randomized control trial was conducted in the neonatal intensive care units of Kalawati Saran Children's Hospital. Clinically stable preterms within the first 7 postnatal days, who had not received painful stimulus 30 min prior to intervention, and who required routine OGT insertion were included. Lingual 24 % sucrose or distilled water (1 ml) was administered 2 min before OGT insertion. The primary outcome was painful response assessed by Premature Infant Pain Profile scale (PIPP), while the secondary outcomes were heart rate and SpO2 changes. The trial is registered with ClinicalTrials.gov ( REGISTRATION NUMBER:NCT 00949104) RESULTS: Sixty preterms were randomized in each group. Final analysis was carried out on 52 subjects in the placebo group and 53 in the sucrose group. The mean intra-procedure PIPP scores were significantly higher than the mean pre-procedure PIPP scores, in the gestational age groups of more than 34 wk, and 32 wk to 33 wk, 6 d, in both the placebo (7.25 vs. 3, and 8.14 vs. 3.14, respectively) and sucrose arm (8.06 vs. 3.21, and 7.18 vs. 4.18, respectively). The mean PIPP scores assessed at 30 s post procedure in the sucrose group were significantly lower than the placebo group (4.32 vs. 5.6, p = 0.014). No significant adverse events were seen. CONCLUSIONS:OGT insertion causes pain in preterms and single dose lingual 24 % sucrose may alleviate this pain.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Pandey M,Datta V,Rehan HSdoi
10.1007/s12098-012-0924-4subject
Has Abstractpub_date
2013-06-01 00:00:00pages
476-82issue
6eissn
0019-5456issn
0973-7693journal_volume
80pub_type
杂志文章,随机对照试验abstract：OBJECTIVE:To investigate the changes in lymphocyte subsets that are caused by infection with different pathogens in children with hand, foot, and mouth disease. METHODS:T lymphocyte subsets were measured in the patients' peripheral blood, and serum, throat swab, and fecal samples were tested for enterovirus. RESULTS:...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-016-2198-8
更新日期：2017-02-01 00:00:00
abstract：:Fevers in children are mainly due to infection, malignancy or inflammatory conditions. Rheumatologists have an important role in the care of inflammatory conditions, many of which are associated with fevers. Seven conditions, the hereditary recurrent fever syndromes, have been defined with the presenting symptom of re...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-010-0206-y
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVE:To develop a height and weight based equation to estimate total body water (TBW) in Sri Lankan children. METHODS:Cross sectional descriptive study done involving 5-15 year old healthy children. Height and weight were measured. TBW was assessed using isotope dilution method (D(2)O) and fat free mass (FFM) cal...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-009-0333-5
更新日期：2010-02-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to determine if attention deficit and hyperactivity disorder (ADHD)/ learning disability (LD) adolescents are more prone to accidents and to investigate the parental mode of coping with that risk. METHODS:One hundred and eight high school pupils diagnosed with ADHD/LD and studying in...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02825823
更新日期：2006-04-01 00:00:00
abstract：:We studied 2447 asymptomatic school children by microscopic examination of urine and culture of a clear voided midstream specimen of urine. Only three children had bacteriuria (0.12%). Urographic abnormalities were detected in both the cases, which could be investigated. This study has shown that asymptomatic bacteriu...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02749724
更新日期：1989-01-01 00:00:00
abstract：:Hypophosphatemic rickets (HR) has generated a lot of interest in recent times. There is need to recognize this disorder and differentiate it from the more common nutritional rickets because the therapy is different. It is also important to emphasize that a detailed clinical examination with pedigree analysis and easil...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02723852
更新日期：1999-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy and safety of Bifilac on reducing the episodes (frequency) and duration of diarrhea induced by rotaviral infection and to evaluate the efficacy of Bifilac to ameliorate the associated symptoms like dehydration and duration of rotaviral shedding in faeces. METHODS:80 children aged bet...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s12098-008-0134-2
更新日期：2008-07-01 00:00:00
abstract：:During the last eight years a total of nine cases of isolated congenital coronary arteriovenous fistula (CAVF) have been diagnosed at our centre. Age of these patients ranged from 11 days to 22 years (mean 6.4 +/- 4.2 years). There were seven male and two female patients. Right and left coronary arteries were the site...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02762180
更新日期：2000-09-01 00:00:00
abstract：:Paracetamol (acetaminophen) has become an antipyretic drug of choice. Due to its widespread use, toxicity secondary to overdose has increased in recent years. Children are especially vulnerable to accidental exposure due to non availability of child proof containers in India. The main clinical features of acute toxici...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF02761132
更新日期：1998-05-01 00:00:00
abstract：OBJECTIVE:To measure the economic output/input ratios for the various options of prevention of rheumatic fever/rheumatic heart disease (RF/RHD) and check the viability of primary prevention vis-à-vis secondary and tertiary preventions. METHODS:Cost accounting of the various prevention options was calculated for each v...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-007-0094-y
更新日期：2007-06-01 00:00:00
abstract：OBJECTIVE:To assess Ankle-Foot-Orthosis (AFO) requirement and ambulation in Duchenne Muscular Dystrophy (DMD) patients seen over a period of 4 y at a multi-disciplinary Neuromuscular disorders clinic (NMD). METHODS:A study was conducted in university quaternary research hospital with DMD patients confirmed by MLPA (mu...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-016-2251-7
更新日期：2017-03-01 00:00:00
abstract：:A large number of complications in thalassemia major are due mainly to iron overload. Deferoxamine in iron-overloaded patients has established that chelation therapy, when given at an adequate dose, reduces iron-related complications. Parenteral administration and the daily nuisance of an infusion pump hinder the opti...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-007-0134-7
更新日期：2007-08-01 00:00:00
abstract：:Asthma is fairly common in pediatric age group and the suffering due to asthma continues to increase despite excellent treatments available. One of the four major components of asthma management is patient education and is critical to the success of asthma management. Reasons for continued suffering include that our m...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,病人教育讲义,评审
doi：
更新日期：2001-09-01 00:00:00
abstract：:Pulmonary actinomycosis is rarely reported in pediatric age. An 11-year-old girl with history of two-month back pain was admitted to our hospital. On physical examination respiratory sounds were diminished on the left upper lung. Chest radiograph revealed a mass in the left upper lobe. Computed tomography showed solit...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-008-0233-0
更新日期：2009-02-01 00:00:00
abstract：:In the pediatric patient, computed tomography (CT) scan as an imaging modality for evaluation of the abdomen is to be used judiciously. The use of correct scanning protocols, single phase scanning, scanning only when required are key factors to minimize radiation doses to the child, while providing diagnostic quality....
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-016-2030-5
更新日期：2016-07-01 00:00:00
abstract：:Epilepsy surgery is safe and effective treatment in children who fail to respond to antiepileptic medications. After failure of two appropriate antiepileptic medications, chances that the child will become seizure free with more or different medications is <5%, and she should be diagnosed with "refractory epilepsy". A...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-014-1541-1
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVE:To find out the incidence and natural history of IgMN in India. METHODS:Renal biopsies of children ≤12 y age of last 6 y were retrospectively evaluated. Their clinical and biochemical presentation were correlated. Patients with systemic diseases/disorders were excluded from the study. RESULTS:Immunoglobulin...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-012-0693-0
更新日期：2012-08-01 00:00:00
abstract：:Advances in diagnosis and treatment along with improved supportive care have contributed to the current survival rates for pediatric malignancies. Recent concept of a truly "cured child" in pediatric oncology envisages not only a biological cure of the disease but a child on par with peers in growth and development ph...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02723807
更新日期：2003-10-01 00:00:00
abstract：:While head injuries are not common in youth sports, they may have catastrophic results. Concussion is also referred to as mild traumatic brain injury (MTBI). Although the occurrence of head injuries has been studied more extensively in American football, the findings have wider application for any MTBI. Recently, more...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF02820676
更新日期：2000-05-01 00:00:00
abstract：:Treatment with tyrosine kinase inhibitors (TKI) is an effective therapy for children and adolescents with chronic phase of chronic myeloid leukemia (CML). For the majority of patients with CML in low- and middle-income countries (LMIC), imatinib is the TKI of choice for reasons of cost, availability, and experience. C...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-020-03234-x
更新日期：2020-06-01 00:00:00
abstract：:Allgrove syndrome consists of triad of Adrenal hypoplasia, Achalasia cardia and Alacrimia. Often the first manifestation of adrenal hypoplasia is Addisonian crisis precipitated by infection or trauma. We present case of a 9-year-old boy who presented in shock due to adrenal failure later confirmed to have Allgove synd...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-007-0179-7
更新日期：2007-10-01 00:00:00
abstract：:The clinical disappearance of the murmur of rheumatic mitral regurgitation after period of time has been documented by many researchers. However no studies have related the disappearance of the murmur with the functional or anatomical state of the mitral valve. This study was done to elucidate the mitral valve status ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02825126
更新日期：1995-11-01 00:00:00
abstract：OBJECTIVE:To study the new ISPAE guidelines in neonates with congenital hypothyroidism and present authors' experience in managing these neonates. METHODS:A retrospective review of all babies who were screened for congenital hypothyroidism in the institution over a period of 5 y was conducted. Details pertaining to ma...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-020-03555-x
更新日期：2020-11-20 00:00:00
abstract：:Despite evidence about the value of high quality postnatal services for the survival, health and wellbeing of the mother and neonate, sub-optimal use of the available services delivered through public sector remains a persistent challenge in India and most low-middle income countries. An extensive search till Dec 31, ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-019-03101-4
更新日期：2020-03-01 00:00:00
abstract：:In this review, the clinical features and management of most commonly encountered acyanotic, left-to-right shunt lesions are discussed. Patients with small defects, especially in childhood, are usually asymptomatic while moderate to large defects in infancy may present with symptoms. Hyperdynamic precordium, widely sp...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF02724429
更新日期：2005-06-01 00:00:00
abstract：OBJECTIVE:Jaundice is a common clinical problem in neonatal period which may result in brain damage even in healthy full term newborns, when it is severe. The aim of this study was to characterize the therapeutic effect of clofibrate in full term neonates who present with nonhemolytic jaundice. METHODS:A clinical cont...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s12098-007-0184-x
更新日期：2007-11-01 00:00:00
abstract：OBJECTIVES:To understand how decisions are made in Intensive Care Unit (ICU) settings where critically-ill children require life-support decisions and what are the perceptions of health professionals and parents. METHODS:In this qualitative study, in-depth, semi-structured, face to face interviews with 8 doctors, 9 nu...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-014-1431-6
更新日期：2014-12-01 00:00:00
abstract：:When a child is diagnosed with epilepsy, counseling regarding the same is done by the treating doctor. Most parents are frightened and have poor knowledge about epilepsy. Therapeutic advice including drug dosage, administration and side effects takes up the major part of physician's time, thereby neglecting important ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-019-02946-z
更新日期：2019-07-01 00:00:00
abstract：:A cross-sectional study was conducted on the children of 146 randomly selected families in Abha, Saudi Arabia. Counting of teeth and examination for caries teeth of children under 12 years of age were done by family visits. The results showed that no child developed teeth before 5 months. By 12 months there were on an...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02722141
更新日期：1990-01-01 00:00:00
abstract：OBJECTIVE:To document the immunization rates, factors associated with incomplete immunization, and missed opportunities for immunizations in children affected by HIV presenting for routine outpatient follow-up. METHODS:A cross-sectional study of immunization status of children affected by HIV presenting for routine ou...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-013-1049-0
更新日期：2014-09-01 00:00:00
