Abstract：
:We have previously shown that breast-fed infants have a considerably larger thymus at 4 months than formula-fed infants. The aim of the present study was to investigate whether breast-feeding also influences the thymic size in late infancy. In a cohort of 50 infants, all being partially breast-fed when recruited at 8 months, ultrasound assessment of the thymic index (a volume estimate) was performed at both 8 and 10 months of age. At 10 months the thymic index was significantly higher in those still being breast-fed compared to infants who had stopped breast-feeding between 8 and 10 months of age (P=0.05). This difference became more significant when controlled for the influence of infectious diseases (P=0.03). In infants still breast-fed at 10 months there was a significant correlation between the number of breast-feeds per day and their thymic index (P=0.01). Conclusion The effect of breast-feeding on thymus size is likely to be caused by immune modulating factors in breast milk. Breast milk influences thymic size in late infancy.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Hasselbalch H,Engelmann MD,Ersboll AK,Jeppesen DL,Fleischer-Michaelsen Kdoi
10.1007/s004310051258keywords:
subject
Has Abstractpub_date
1999-12-01 00:00:00pages
964-7issue
12eissn
0340-6199issn
1432-1076pii
91580964.431journal_volume
158pub_type
杂志文章abstract：UNLABELLED:Infection is a well recognised cause of spontaneous early preterm labour. Preterm labour of infective aetiology is refractory to the use of tocolytic agents and affected women have a higher risk of subsequent chorio-amnionitis and neonatal infection. Antibiotics used prophylactically for the prevention of pr...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/pl00014313
更新日期：1999-12-01 00:00:00
abstract：:This review deals with podocyte proteins that play a significant role in the structure and function of the glomerular filter. Genetic linkage studies has identified several genes involved in the development of nephrotic syndrome and contributed to the understanding of the pathophysiology of glomerular proteinuria and/...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-009-1017-x
更新日期：2009-11-01 00:00:00
abstract：:Cough and wheezing are the predominant symptoms of acute bronchitis. Hitherto, the evaluation of respiratory symptoms was limited to subjective methods such as questionnaires. The main objective of this study was to objectively determine the time course of cough and wheezing in children with acute bronchitis. The impa...
journal_title：European journal of pediatrics
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1007/s00431-019-03426-4
更新日期：2019-09-01 00:00:00
abstract：UNLABELLED:The surgical approach to the inguinal canal in girls is identical to that in boys. The sliding hernia which contains the ovary with or without the fallopian tube occurs occasionally in female patients. In our clinical experience, we found that a hydrocele in the labium, also presenting with an asymptomatic p...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-003-1226-7
更新日期：2003-07-01 00:00:00
abstract：:Patients with Turner syndrome (n = 33) were subjected to a sequential oestrogen/gestagen replacement therapy (21 days 2 mg oestradiol valerate plus 0.5 mg norgestrel for 10 days) for 1-4 years. In individuals aged 12-17 years, growth velocities before treatment ranged between 2.9 and 1.9 cm/year and increased to 6.8-3...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00439400
更新日期：1986-09-01 00:00:00
abstract：:Iliac vessel disruption following blunt trauma is an unusual presentation, particularly in the absence of an orthopaedic injury. We present the unique case of a 14-year-old boy who sustained a blunt bicycle handlebar impalement that resulted in complete transection of the external iliac artery and laceration of the ex...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-012-1767-8
更新日期：2012-12-01 00:00:00
abstract：:A pure growth of Branhamella catarrhalis was obtained from a purulent bronchial exudate in a 28-month-old Rwandese girl, hospitalized for acute inspiratory dyspnoea with fever. The outcome was favourable under treatment with ampicillin, although the isolate was shown to produce a beta-lactamase in vitro. ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00442307
更新日期：1985-03-01 00:00:00
abstract：UNLABELLED:This study assessed health-related quality of life (HRQoL) reported by overweight adolescents and compared to their parent-proxy perception of HRQoL, according to adolescent gender, adolescent age, and parent gender. Patients and a total of 179 adolescents aged 10 to 18 years with excess weight were evaluate...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-013-2050-3
更新日期：2013-10-01 00:00:00
abstract：:Vitamin D is important for calcium homeostasis, muscle, and bone health. It has also immunomodulatory capacities in vivo and in vitro. Regulatory T cells (Treg) have been found to suppress a number of T cell-mediated immune disorders, including allergic responses and autoimmune diseases. This study aimed to investigat...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-012-1688-6
更新日期：2012-08-01 00:00:00
abstract：:Although thyroid medications are frequently prescribed during pregnancy, paediatricians treating the respective neonates often have no information about the underlying maternal thyroid disease, and inconsistencies in postnatal diagnostics may result. We analysed a cohort of 1819 mothers admitted for delivery in 1 year...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-018-3232-9
更新日期：2018-11-01 00:00:00
abstract：UNLABELLED:Suppurative parotitis is uncommon in newborns. During a 9-year study period, five cases of neonatal suppurative parotitis were detected in 3,624 hospital admissions. The relative risk of developing neonatal suppurative parotitis in admitted infants was 5.52 (0.62-49.35). Staphylococcus aureus was the causati...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310051079
更新日期：1999-04-01 00:00:00
abstract：UNLABELLED:High-flow nasal cannula (HFNC) is a widely used ventilatory support in children with bronchiolitis in the intensive care setting. No data is available on HFNC use in the general pediatric ward. The aim of this study was to evaluate the feasibility of HFNC oxygen therapy in infants hospitalized in a pediatric...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-013-2094-4
更新日期：2013-12-01 00:00:00
abstract：:We examined the long-term outcome in 111 children who had convulsions during shigellosis and were followed for 3-18 years after the incident. No deaths or persistent motor deficits occurred as sequellae. Poor coordination of fine hand movements were noted in 3.3% of the 92 children who had no pre-existing neurological...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02106298
更新日期：1990-01-01 00:00:00
abstract：:The aim of this retrospective study was to describe the epidemiology and spectrum of infections of admitted pediatric refugees and asylum seekers in a tertiary referral hospital in a high-income country in Europe. We identified recent refugees and asylum seekers < 18 years of age admitted to the University Children's ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-017-3014-9
更新日期：2017-12-01 00:00:00
abstract：:We present clinical and biochemical data on a further patient with hyperargininaemia and the results of neurophysiological tests both before and during dietary treatment with an essential amino acid mixture. With normalisation of plasma arginine concentrations, neurological functions improved and brain stem auditory e...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02171562
更新日期：1990-02-01 00:00:00
abstract：:Two siblings became very ill after BCG inoculation in the newborn period. A generalized BCG infection was assumed from the clinical symptomatology and the histological findings. Later on the boy suffered from enteric salmonellosis and osteomyelitis caused by the same organism, and as a todler he had intestinal pseudot...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00445481
更新日期：1976-02-04 00:00:00
abstract：UNLABELLED:Cystic adenomatoid malformation of the lung (CAML) is a rare pulmonary maldevelopment resulting from an abnormal growth of the terminal bronchial structures. This study proposes a possible management of prenatally diagnosed CAML. A group of nine cases of CAML diagnosed prenatally between January 1990 and Dec...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310051233
更新日期：1999-11-01 00:00:00
abstract：:In fourteen infants, aged 9--60 days, with generalized oedema seen during a one year period the common denominator was the administration of dipyrone one to two days prior to the development of oedema. None of the other causes of oedema in early life could be incriminated in any of these babies. Pediatricians should b...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00477053
更新日期：1977-11-04 00:00:00
abstract：UNLABELLED:The need to reappraise sedation policy is dictated by newer noninvasive imaging modalities. In this study we evaluate the safety and efficacy of rectally-administered thiopental in children undergoing MRI. Eighty-three consecutive patients with congenital heart disease (mean age 2.9 years, SD 2.5) undergoing...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：UNLABELLED:In phenylketonuria, compliance and diet is a difficult issue; it is hard to quantify and is under-researched. It is influenced by many factors. Failure to consume prescribed quantity of protein substitute has been commonly reported and is probably affected by their acceptability, format and timing of adminis...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/pl00014375
更新日期：2000-10-01 00:00:00
abstract：:Two patients developed clinical features of intracranial bleeding--which were confirmed by computerized axial tomograms--during their induction therapy for acute lymphocytic leukemia. Coagulation studies showed clotting abnormalities including severe hypofibrinogenemia. These findings most probably were related to the...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00443266
更新日期：1981-11-01 00:00:00
abstract：:Six patients are described with a combination of early onset of neurological symptoms, gross cerebral changes and elevated concentrations of pyruvate and lactate in cerebrospinal fluid. Although at least five of the six patients appear to have a generalised defect in pyruvate metabolism, reflected in deficient pyruvat...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00442603
更新日期：1988-01-01 00:00:00
abstract：:The main goal for the neonatologist is to facilitate the adaptation to extra-uterine life during initial transition, while minimizing lung injury opening and protecting the premature lung from the first breath onwards. An appropriate management from birth should lead to the achievement of an early functional residual ...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-017-2984-y
更新日期：2017-10-01 00:00:00
abstract：UNLABELLED:Extremely immature newborns develop a self-limiting normal anion gap metabolic acidosis in early life. This study examined the natural history of this acidosis in a population of infants of gestation less than 26 weeks in the first 14 days of life. The acidosis was maximal on day 4 with a mean base deficit o...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-014-2364-9
更新日期：2015-01-01 00:00:00
abstract：:Twenty patients with enzymatically proven glycogen storage disease type III (GSD III) aged 3-30 years underwent cardiological evaluation. Seventeen showed subclinical evidence of cardiac involvement in form of ventricular hypertrophy on ECG. Of 16 patients in whom an ECG examination was performed, 13 had abnormal echo...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00443106
更新日期：1989-08-01 00:00:00
abstract：:Using a randomized double blind study design, the bronchodilating effect of 200 micrograms inhaled oxitropium bromide (OB) was compared with 200 micrograms inhaled fenoterol (F) after an interval of 20 min, in 20 asthmatic children aged 12.7 years (range: 4.9-15.1 years), suffering from mild bronchoconstriction (mean ...
journal_title：European journal of pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF02190670
更新日期：1994-08-01 00:00:00
abstract：:The effect of intranasal LH-RH on cryptorchidism was investigated in 45 prepubertal boys with 68 undescended testes. A daily dose of 1.2 mg LH-RH was given for 4 weeks. A total of 16 testes (24%) descended. Follow-up examination 5 years later showed that relapse had occurred in two cases. Fifty-two testes did not desc...
journal_title：European journal of pediatrics
pub_type： 临床试验,杂志文章
doi：10.1007/BF00452869
更新日期：1987-01-01 00:00:00
abstract：:One year's experience in screening for congenital hypothyroidism in Greece is reported. Thyroid stimulating hormone (TSH) determination by a radioimmunoassay on dried blood spots was selected as the screening method. During the first year of screening 75,879 newborn infants were tested from Guthrie blood spots taken o...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00441314
更新日期：1981-10-01 00:00:00
abstract：UNLABELLED:Two years after an accident resulting in either a mild head injury or a fractured bone, two groups of 22 children each, aged 4-14 years, were examined for the existence of any neurobehavioural symptoms by means of a standardized questionnaire filled out by their caretakers. Selection of the children was base...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310051061
更新日期：1999-03-01 00:00:00
abstract：:Serum immunoglobulin levels and naturally occurring antibody titres against Streptococcus pneumoniae were measured in seven children aged 1-1.9 years with recurrent pneumococcal acute otitis media (AOM). Three of them had low IgG2 levels. Mean antibody levels of anti-pneumococcal IgG1 and anti-pneumococcal IgG2 were s...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01958979
更新日期：1994-03-01 00:00:00
