Intranasal LH-RH treatment of cryptorchidism. A clinical trial and 5 years follow-up.

Abstract:

:The effect of intranasal LH-RH on cryptorchidism was investigated in 45 prepubertal boys with 68 undescended testes. A daily dose of 1.2 mg LH-RH was given for 4 weeks. A total of 16 testes (24%) descended. Follow-up examination 5 years later showed that relapse had occurred in two cases. Fifty-two testes did not descend during the LH-RH treatment. However, seven of these testes descended spontaneously during puberty. So far surgical treatment has been carried out in 39 of the remaining 45 testes. Anatomical anomalies (ectopic position of the testis, open processus vaginalis, abnormal epididymis) explained the failure of LH-RH to cause descent in the majority of the surgically treated cases.

journal_name

Eur J Pediatr

authors

Bertelsen A,Thorup J,Pedersen PV,Mauritzen K,Skakkebaek NE

doi

10.1007/BF00452869

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

S40-1

eissn

0340-6199

issn

1432-1076

journal_volume

146 Suppl 2

pub_type

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