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Maculopapular rash in the convalescent phase of Kawasaki disease: case series and literature review.

Abstract：

UNLABELLED:Intravenous immunoglobulin (IVIG) is currently the standard treatment for Kawasaki disease (KD). Although IVIG therapy is generally well tolerated, several minor adverse reactions have been reported. We report a patient with KD treated with IVIG, who developed a cutaneous reaction in the convalescent phase (approximately 10 days after therapy). We identified seven additional KD cases with a similar presentation, accounting for 9.3 % of KD patients at our hospital. We performed a literature review and found that a maculopapular rash could be observed approximately 10 days after IVIG treatment, in patients with and those without KD. CONCLUSION:Maculopapular rash can occur in nearly 10 % of IVIG-treated children with KD in our cohort, approximately 10 days after treatment. A delayed-onset adverse event of IVIG could be a causative etiology of this unrecognized eruption.

journal_name

Eur J Pediatr

journal_title

European journal of pediatrics

authors

Takeuchi M,Oda Y,Suzuki I

doi

10.1007/s00431-012-1898-y

subject

Has Abstract

pub_date

2013-03-01 00:00:00

pages

405-7

issue

3

eissn

0340-6199

issn

1432-1076

journal_volume

172

pub_type

杂志文章,评审

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